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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                        --------------------------------

                                    FORM 8-K
                        --------------------------------


                                 CURRENT REPORT
                     PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

        DATE OF REPORT (DATE OF EARLIEST EVENT REPORTED): AUGUST 1, 2005

                             -----------------------

                         MICROTEK MEDICAL HOLDINGS, INC.
             (Exact name of registrant as specified in its charter)
                            -------------------------



                                                                  
           GEORGIA                            0-24866                        58-1746149
           -------                            -------                        ----------
(State or Other Jurisdiction         (Commission File Number)               (IRS Employer
      of Incorporation)                                                  Identification No.)


          13000 DEERFIELD PARKWAY, SUITE 300, ALPHARETTA, GEORGIA 30004
               (Address of principal executive office) (zip code)

       REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE: (678) 896-4400


          (Former name or former address, if changed since last report)

                            -------------------------

     Check the  appropriate  box below if the Form 8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_|  Written  communications  pursuant to Rule 425 under the  Securities Act (17
     CFR 230.425)

|_|  Soliciting  material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
     240.14a-12)

|_|  Pre-commencement   communications  pursuant  to  Rule  14d-2(b)  under  the
     Exchange Act (17 CFR 240.14d-2(b))

|_|  Pre-commencement   communications  pursuant  to  Rule  13e-4(c)  under  the
     Exchange Act (17 CFR 240.13e-4(c))

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ITEM 1.01 ENTRY INTO A MATERIAL DEFINITIVE AGREEMENT.

     As  described  in  Item  5.02  below,   Microtek  Medical  Holdings,   Inc.
     ("Company")  hired Mark J.  Alvarez as the Chief  Operating  Officer of the
     Company  effective  August 1, 2005. In connection  with the foregoing,  the
     Company and Mr. Alvarez entered into an Employment  Agreement  effective as
     of  August 1,  2005.  The  Employment  Agreement  has a term of 38  months,
     specifies  a  minimum   annual  base  salary  of  $225,000,   and  contains
     restrictive  covenants  including  covenants  relating to the protection of
     confidential  information and restricting  competition against the Company.
     Mr.  Alvarez was also  granted a one time  signing  bonus of  $10,000.  Mr.
     Alvarez is also  eligible  for a bonus up to 50% of his annual  base salary
     subject to the terms and  conditions  of the Annual  Executive  Performance
     Bonus Plan.  The  Employment  Agreement is terminable by the Company or the
     employee  with or without  cause.  In the event of the  termination  of the
     Employment  Agreement by the Company  without cause (as the term "cause" is
     defined in the Employment Agreement),  Mr. Alvarez is generally entitled to
     severance  equal to one year's salary and the Company will maintain in full
     force and effect at the Company's  expense for the continued benefit of the
     employee and his dependents until the first anniversary of the date of such
     termination of employment (or, if earlier,  upon the  commencement  date of
     equivalent  benefits from a new  employer) the Company's  health and dental
     insurance  benefits.  In the  event of any  termination  of the  employee's
     employment  within six months following a change of control (as defined) of
     the Company, other than a termination of employment as a result of death or
     disability  or cause,  the  employee is  entitled  to the same  benefits as
     payable in the event of a termination of employment by the Company  without
     cause.

     The Company issued a press release  publicly  announcing the appointment of
     Mark J. Alvarez as the Company's  Chief  Operating  Officer on the same day
     the Company filed this Current Report.

ITEM 5.02 DEPARTURE OF DIRECTORS OR PRINCIPAL  OFFICERS;  ELECTION OF DIRECTORS;
APPOINTMENT OF PRINCIPAL OFFICERS.

     Mark J.  Alvarez  was  appointed  Chief  Operating  Officer of the  Company
     effective  August 1, 2005. Prior to joining the Company and since 2002, Mr.
     Alvarez  served  as the  President  of Recall  North  America,  a  document
     management  solutions company with 2,000 employees across 150 facilities in
     the U.S.,  Canada and Mexico.  Prior to joining Recall North  America,  Mr.
     Alvarez served in progressively more senior positions with General Electric
     Company from 1983 to 2002, initially with GE Medical Systems and thereafter
     in more senior  leadership  positions within General  Electric's  Corporate
     Marketing  and  Sales  group  across  all of  the  industrial  and  capital
     businesses of General  Electric  Company.  Mr. Alvarez earned his B.A. from
     the University of Louisville and his M.B.A. from Illinois State University.

     A description  of the Company's  Employment  Agreement  with Mr. Alvarez is
     contained in Item 1.01 above.



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SECTION 9 - FINANCIAL STATEMENTS AND EXHIBITS.

ITEM 9.01  FINANCIAL STATEMENTS AND EXHIBITS.

     (a) Financial Statements.

         Not applicable

     (b) Pro Forma Financial Information.

         Not applicable

     (c) Exhibits.

         Exhibit Number       Description
         --------------       -----------

               10.1           Employment  Agreement  effective  as of  August 1,
                              2005 with Mark Alvarez




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                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
Company  has  duly  caused  this  report  to be  signed  on  its  behalf  by the
undersigned hereunto duly authorized.

                                            MICROTEK MEDICAL HOLDINGS, INC.



Date: August 4, 2005                        By: /s/ Dan R. Lee
                                                --------------------------------
                                                Dan R. Lee
                                                Chairman, President and Chief
                                                Executive Officer



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                                  EXHIBIT INDEX



         Exhibit Number       Description
         --------------       -----------

               10.1           Employment  Agreement  effective  as of  August 1,
                              2005 with Mark Alvarez





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