As filed with the Securities and Exchange Commission on June 24, 1999

                                            Registration Statement No. 333-_____


                       SECURITIES AND EXCHANGE COMMISSION
 -------------------------------------------------------------------------------

                             Washington, D.C. 20549

                                    FORM S-8
                             REGISTRATION STATEMENT
                                      Under
                           The Securities Act of 1933

                             ISOLYSER COMPANY, INC.
             (Exact name of registrant as specified in its charter)

         Georgia                                            58-1746149
  (State or Other Jurisdiction of                        (I.R.S. Employer
  Incorporation or Organization)                         Identification No.)

                        4320 International Boulevard, NW
                             Norcross, Georgia 30093

   (Address, including zip code, of registrant's principal executive offices)

                          1999 Long-Term Incentive Plan
                              (Full Title of Plan)

                               Migirdic Nalbantyan
                        4320 International Boulevard, NW
                             Norcross, Georgia 30093
                                 (770) 806-9898
          (Name and address, including zip code, and telephone number,
                   including area code, of agent for service)

                                    Copy to:

                              Stephen D. Fox, Esq.
                          Arnall Golden & Gregory, LLP
                            2800 One Atlantic Center
                           1201 West Peachtree Street
                           Atlanta, Georgia 30309-3450



                         CALCULATION OF REGISTRATION FEE
- ------------------------------------------------------------------------------------------------------------------------

                                                     Proposed maximum        Proposed maximum           Amount of
Title of each class of              Amount to be     offering price per      aggregate                  registration
securities to be registered         registered       share(1)                offering price(1)          fee

- ------------------------------------------------------------------------------------------------------------------------
                                                                                           
Common Stock, $.001 par value       1,200,000        $3.944                  $4,612,800                $1,283.00

- ------------------------------------------------------------------------------------------------------------------------

(1)  Estimated  solely for purposes of calculating the registration fee pursuant
     to Rule 457 (c) and (h) based on the  average of the bid and asked price of
     the  Company's  Common  Stock on June 21,  1999,  as reported by The Nasdaq
     Stock Market.


840108v1


                                     PART II

Item 3. Incorporation of Documents by Reference.

           The  following  documents  filed  with the  Securities  and  Exchange
Commission are hereby incorporated by reference:

     (a) The Company's  Annual  Report on Form 10-K for the year ended  December
31, 1998, as amended (File No. 0-24866);

     (b) The Company's Quarterly Report on Form 10-Q for the quarter ended March
31, 1999 (File No. 0-24866) filed May 14, 1999; and

     (c) The  description  of the  Registrant's  Common  Stock  set forth in the
Registrant's Form 8-A Registration Statements (File No. 0-24866) filed September
27, 1994 and December 20, 1996.

           All  documents  subsequently  filed  by the  Registrant  pursuant  to
Sections 13(a),  13(c), 14 and 15(d) of the Securities  Exchange Act of 1934, as
amended (the "Exchange Act"), after the filing hereof and prior to a filing of a
post-effective amendment which indicates that all securities offered hereby have
been sold or which de-registers all securities remaining unsold, shall be deemed
to be incorporated by reference  herein and to be a part hereof from the date of
the filing of such reports and documents.

Item 4. Description of Securities.

           Not applicable.

Item 5. Interests of Named Experts and Counsel.

           Not applicable.

Item 6. Indemnification of Directors and Officers.

           Pursuant  to  Sections  14-2-851  through  14-2-857  of  the  Georgia
Business  Corporation Code, as amended, the directors,  officers,  employees and
agents of the Company may, and in some cases must, be indemnified by the Company
under certain  circumstances  against  expenses and  liabilities  incurred by or
imposed upon them as a result of actions,  suits or proceedings  brought against
them as  directors,  officers,  employees  and agents of the Company  (including
actions, suits or proceedings brought against them for violations of the federal
securities   laws).   Article  Nine  of  the  Company's   Bylaws   provides  for
indemnifications  of  directors to the fullest  extent  permitted by the Georgia
Business  Corporation Code. These provisions  generally mirror Sections 14-2-851
through 14-2-857 of the Georgia Business Corporation Code.

                                      II-2


           Insofar  as  indemnification   for  liabilities   arising  under  the
Securities Act of 1933, as amended,  may be permitted to directors,  officers or
persons  controlling  the Company  pursuant to the  foregoing  provisions of the
Georgia Business Corporation Code and the Company's Bylaws, the Company has been
informed  that  indemnification  is considered  by the  Securities  and Exchange
Commission to be against public policy and therefore unenforceable.

Item 7. Exemption from Registration Claimed.

           Not applicable.

Item 8. Exhibits.

         Exhibit No.     Description

         5               Opinion of counsel as to legality of the
                         securities being registered

         10(a)           1999  Long-Term  Incentive  Plan  (incorporated  by
                         reference to Exhibit A to the  Company's Schedule
                         14A filed with the Commission on April 19, 1999)

         23(a)           Consent  of  Arnall  Golden &  Gregory,  LLP
                         (included in opinion filed as Exhibit 5)

         23(b)           Consent of Deloitte & Touche LLP

         24              Power of Attorney (included on page II-5)

Item 9. Undertakings.

         The undersigned Registrant hereby undertakes as follows:

         (1) To file, during any period in which offers or sales are being made,
a post-effective amendment to this registration statement:

      (i)    To include any prospectus required by Section 10(a)(3) of the Act;

     (ii)     To  reflect  in the  prospectus  any  facts or events
              arising after the effective date of the  registration
              statement   (or  the   most   recent   post-effective
              amendment   thereof)   which,   individually   or  in
              aggregate,  represent  a  fundamental  change  in the
              information set forth in this registration statement;

                                      II-3


     (iii)    To include any material  information  with respect to
              the plan of distribution not previously  disclosed in
              this registration statement or any material change to
              such information in this registration statement;

provided,  however,  that the  undertakings set forth in paragraphs (i) and (ii)
above  do  not  apply  if  the   information   required  to  be  included  in  a
post-effective  amendment by those  paragraphs is contained in periodic  reports
filed by the  Registrant  pursuant  to  Section  13(a) or  Section  15(d) of the
Exchange Act that are incorporated by reference in this registration statement.

         (2) That, for the purpose of determining  any liability  under the Act,
each such  post-effective  amendment  shall be  deemed to be a new  registration
statement relating to the securities  offered therein,  and the offering of such
securities  at the time  shall be deemed to be the  initial  bona fide  offering
thereof.

         (3) To remove from registration by means of a post-effective  amendment
any of the securities being registered which remain unsold at the termination of
the offering.

         (4) That, for purposes of determining  any liability under the Act each
filing of the  registrant's  annual report  pursuant to Section 13(a) or Section
15(d) of the Exchange  Act (and,  where  applicable,  each filing of an employee
benefit plan's annual report pursuant to Section 15(d) of the Exchange Act) that
is incorporated by reference in this  registration  statement shall be deemed to
be a new registration  statement relating to the securities offered therein, and
the offering of such  securities  at that time shall be deemed to be the initial
bona fide offering thereof.

         (5) Insofar as  indemnification  for liabilities  arising under the Act
may  be  permitted  to  directors,  officers,  and  controlling  persons  of the
Registrant pursuant to the foregoing provisions or otherwise, the Registrant has
been advised that in the opinion of the Securities and Exchange  Commission such
indemnification  is  against  public  policy  as  expressed  in the  Act and is,
therefore,  unenforceable. In the event that a claim for indemnification against
such liabilities  (other than the payment by the Registrant of expenses incurred
or paid by a director,  officer or  controlling  person of the Registrant in the
successful  defense of any  action,  suit or  proceeding)  is  asserted  by such
director,  officer or controlling person in connection with the securities being
registered, the Registrant will, unless in the opinion of its counsel the matter
has been  settled by  controlling  precedent,  submit to a court of  appropriate
jurisdiction the question whether such  indemnification  by it is against public
policy as expressed in the Act and will be governed by the final adjudication of
such issue.



                         [SIGNATURES ON FOLLOWING PAGE]

                                      II-4



                                   SIGNATURES


         In accordance with the  requirements of the Securities Act of 1933, the
Registrant certifies that it has reasonable grounds to believe that it meets all
of the  requirements  of filing  on Form S-8 and  authorized  this  registration
statement to be signed on its behalf by the undersigned, in the City of Atlanta,
State of Georgia, on June 23, 1999.


                               ISOLYSER COMPANY, INC.



                               By: /s/ MIGIRDIC NALBANTYAN
                                   ----------------------------------
                                   Migirdic Nalbantyan, President and
                                   Chief Executive Officer



                                POWER OF ATTORNEY

         KNOW ALL MEN BY THESE PRESENTS that each person whose signature appears
below  constitutes and appoints  Migirdic  Nalbantyan and Peter A. Schmitt,  and
each of them,  as his true and lawful  attorneys-in-fact  and agents,  with full
power of substitution  and  resubstitution,  for him and in his name,  place and
stead,  in any and all  capacities,  to sign any and all  amendments  (including
post-effective  amendments) to this Registration Statement, and to file the same
with all exhibits thereto, and other documents in connection therewith, with the
Securities and Exchange  Commission,  granting unto said  attorneys-in-fact  and
agents,  and each of them,  full power and  authority to do and perform each and
every  act and  thing  requisite  and  necessary  to be done  in and  about  the
premises,  as  fully  to all  intents  and  purposes  as he might or could do in
person,  hereby  ratifying and  confirming all that said  attorneys-in-fact  and
agents,  or either  of them,  or their or his  substitute  or  substitutes,  may
lawfully do or cause to be done by virtue hereof.








                    [ADDITIONAL SIGNATURES ON FOLLOWING PAGE]

                                      II-5



         Pursuant  to the  requirements  of the  Securities  Act of  1933,  this
Registration  Statement on Form S-8 was signed by the  following  persons in the
capacities indicated on June 23, 1999.

SIGNATURE                                            TITLE

/s/ MIGIRDIC NALBANTYAN             President, Chief Executive Officer and
Migirdic Nalbantyan                 Director (principal executive officer)

/s/ TRAVIS W. HONEYCUTT             Executive Vice President, Secretary and
Travis W. Honeycutt                 Director

/s/ DAN R. LEE                      Executive Vice President and Director
Dan R. Lee

/s/ GENE R. MCGREVIN                Chairman of the Board of Directors
Gene R. McGrevin

                                    Director
Rosdon Hendrix

/s/ KENNETH F. DAVIS                Director
Kenneth F. Davis

                                    Director
John E. McKinley

                                    Director
Ronald L. Smorada

/s/ PETER A. SCHMITT                Executive Vice President, Chief Financial
Peter A. Schmitt                    Officer and Treasurer (principal financial
                                    and accounting officer)

                                 EXHIBIT INDEX


Exhibit No.     Description
- -----------     -----------

5*              Opinion of counsel as to legality of the
                securities being registered

10(a)           1999  Long-Term  Incentive  Plan  (incorporated  by
                reference to Exhibit A to the  Company's Schedule 14A
                filed with the Commission on April 19, 1999)

23(a)           Consent  of  Arnall  Golden &  Gregory,  LLP
                (included in opinion filed as Exhibit 5)

23(b)*          Consent of Deloitte & Touche LLP

24              Power of Attorney (included on page II-5)

- -------------------
*   Filed herewith.


840108v1