UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) [x] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended June 30, 2001 OR [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period from ______ to ______ Commission File Number: 0-21990 OXiGENE, INC. - -------------------------------------------------------------------------------- (Exact name of Registrant as specified in its charter) Delaware 13-3679168 - -------------------------------------------------------------------------------- (State or other jurisdiction of (IRS Employer incorporation or organization) Identification No.) 321 ARSENAL STREET WATERTOWN, MA 02472 - -------------------------------------------------------------------------------- (Address of principal executive offices, including zip code) (617) 673-7800 - -------------------------------------------------------------------------------- (Telephone number, including area code) Not applicable - -------------------------------------------------------------------------------- (Former name, former address and former fiscal year, if changed since last report) Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes [X] No [ ] As of August 3, 2001, there were 11,373,593 shares of the Registrant's Common Stock issued and outstanding and 42,000 shares of the Registrant's Common Stock issuable but not outstanding. OXiGENE, INC. CAUTIONARY FACTORS THAT MAY AFFECT FUTURE RESULTS ------------------------------------------------- Our disclosure and analysis in this report contain "forward-looking statements." Forward-looking statements give our current expectations or forecasts of future events. You can identify these statements by the fact that they do not relate strictly to historic or current facts. They use words such as "anticipate," "estimate," "expect," "project," "intend," "plan," "believe," and other words and terms of similar meaning. These include statements, among others, related to future actions, prospective products or product approvals, future performance or results of current and anticipated products, sales efforts, expenses, and the outcome of contingencies, such as financial results. From time to time, we also may provide oral or written forward-looking statements in other materials we release to the public. Any or all of our forward-looking statements in this report and in any other written and oral statements we make may turn out to be wrong. They can be affected by inaccurate assumptions we might make or by known or unknown risks and uncertainties. Consequently, no forward-looking statement can be guaranteed. Actual results may vary materially. Among the uncertainties that may cause differences include, but are not limited to, the availability of necessary funds and the ability to raise capital when needed and on reasonable terms, the efficacy of our technology and its efficacy at acceptable dosage levels, developing the necessary manufacturing processes, gaining all necessary regulatory approvals and protecting the intellectual property developed through our joint venture with Peregrine Pharmaceuticals (formerly Techniclone Corporation), forming ARCUS Therapeutics, LLC. We undertake no obligation to publicly update forward-looking statements, whether as a result of new information, future events or otherwise. You are advised, however, to consult any further disclosures we make in our reports to the Securities and Exchange Commission including our 10-Q, 8-K and 10-K reports. Our filings list various important factors that could cause actual results to differ materially from expected and historic results. We note these factors for investors as permitted by the Private Securities Litigation Reform Act of 1995. You should understand that it is not possible to predict or identify all such factors. Consequently, you should not consider any such list to be a complete set of all potential risks or uncertainties. -ii- INDEX Page No. -------- PART I - FINANCIAL INFORMATION...............................................1 Item 1. Financial Statements..............................................1 Condensed Consolidated Balance Sheets.............................1 Condensed Consolidated Statements of Operations...................2 Condensed Consolidated Statements of Cash Flows...................3 Notes to Condensed Consolidated Financial Statements..............4 Item 2. Management's Discussion and Analysis of Financial Condition and Results of Operations.......................................5 Item 3. Quantitative and Qualitative Disclosures about Market Risks.......9 PART II - OTHER INFORMATION.................................................10 Item 1. Legal Proceedings................................................10 Item 2. Changes in Securities and Use of Proceeds........................10 Item 3. Defaults upon Senior Securities..................................10 Item 4. Submission of Matters to a Vote of Security Holders..............10 Item 5. Other Information................................................11 Item 6. Exhibits and Reports on Form 8-K.................................11 Signatures..................................................................12 -iii- PART I - FINANCIAL INFORMATION ITEM 1. FINANCIAL STATEMENTS OXIGENE, INC. Condensed Consolidated Balance Sheets (All amounts, except share amounts, in thousands of dollars) (Unaudited) June 30, December 31, 2001 2000 ----------- ------------ ASSETS Current assets: Cash and cash equivalents $ 22,802 $ 27,063 Available-for-sale security -0- 549 Prepaid expenses 111 287 Interest receivable 147 277 Other 65 61 -------- -------- Total current assets 23,125 28,237 Furniture, fixtures and equipment, at cost 956 827 Accumulated depreciation (259) (173) -------- -------- Net property and equipment 697 654 License agreements, net of accumulated amortization 2,088 2,236 Deposits 85 102 -------- -------- Total assets $ 25,995 $ 31,229 ======== ======== LIABILITIES AND STOCKHOLDERS' EQUITY Current liabilities: Amount payable under sub-license agreement - current $ 255 $ 251 Accrued expenses: Research and development expenses 420 687 Other accrued expenses 290 499 Other payables 478 494 -------- -------- Total current liabilities 1,443 1,931 Amount payable under sub-license agreement - noncurrent 577 707 Deferred licensing revenue 7,178 7,445 Stockholders' equity Common stock, $0.01 par value: Authorized shares - 60,000,000 shares Issued and outstanding - 11,373,593 at June 30, 2001 and December 31, 2000 114 114 Common stock issuable - 42,000 shares at June 30, 2001 and December 31, 2000 380 370 Additional paid-in capital 82,113 81,984 Accumulated deficit (62,384) (56,502) Accumulated other comprehensive income (loss) 454 (973) Notes receivable (3,705) (3,609) Deferred compensation (175) (238) -------- -------- Total stockholders' equity 16,797 21,146 -------- -------- Total liabilities and stockholders' equity $ 25,995 $ 31,229 The accompanying notes are an integral part of this statement. -1- OXIGENE, INC. Condensed Consolidated Statements of Operations (All amounts in thousands, except per share data) (Unaudited) Three months ended Six months ended June 30, June 30, ------------------------- ------------------------- 2001 2000 2001 2000 -------- -------- -------- -------- REVENUES Licensing revenue $ 491 $ 380 $ 1,248 $ 863 Unrealized gain on short-term investment -0- 267 -0- 267 Interest income 166 529 518 978 -------- -------- -------- -------- Total revenues 657 1,176 1,766 2,108 EXPENSES Costs relating to licensing revenue 358 249 982 596 Amortization of license agreement 74 24 148 49 Research and development 2,021 1,780 3,272 4,257 General and administrative 1,472 586 2,659 1,464 Loss on sale and write-down of available-for-sale security 452 -0- 551 -0- Interest expense 19 32 36 57 -------- -------- -------- -------- Total expenses 4,396 2,671 7,648 6,423 -------- -------- -------- -------- NET LOSS $ (3,739) $ (1,495) $ (5,882) $ (4,315) ======== ======== ======== ======== NET LOSS $ (3,739) $ (1,495) $ (5,882) $ (4,315) OTHER COMPREHENSIVE LOSS: Unrealized loss from available- for-sale security including reclassification adjustment for loss included in net loss 1,041 -0- 1,451 -0- Foreign currency translation adjustment (19) (249) (24) (303) -------- -------- -------- -------- Total other comprehensive income (loss) 1,022 (249) 1,427 (303) -------- -------- -------- -------- COMPREHENSIVE LOSS $ (2,717) $ (1,744) $ (4,455) $ (4,618) ======== ======== ======== ======== NET LOSS PER COMMON SHARE $ (0.33) $ (0.13) $ (0.52) $ (0.38) ======== ======== ======== ======== WEIGHTED AVERAGE NUMBER OF COMMON SHARES OUTSTANDING 11,233 11,310 11,226 11,296 ======== ======== ======== ======== The accompanying notes are an integral part of this statement. -2- OXIGENE, INC. Condensed Consolidated Statements of Cash Flows (All amounts in thousands) (Unaudited) Six months ended June 30, 2001 2000 -------- -------- OPERATING ACTIVITIES Net loss $ (5,882) $ (4,315) Adjustment to reconcile net loss to cash (used in) provided by operating activities: Unrealized gain on short-term investment -0- (267) Loss on sale and write-down of available-for-sale security 551 -0- Depreciation 87 28 Compensation related to issuance of options and stock appreciation rights 105 110 Amortization of licensing revenue (267) (267) Amortization of licensing agreement 148 49 Changes in operating assets and liabilities: Accounts receivable - license agreement -0- 9,250 Prepaid expenses and other current assets 281 560 Accounts payable and accrued expenses (430) (1,268) -------- -------- Net cash (used in) provided by operating activities (5,407) 3,880 FINANCING ACTIVITIES Proceeds from issuance of common stock and capital contribution -0- 357 -------- -------- Net cash provided by financing activities -0- 357 INVESTING ACTIVITIES Investment in joint venture -0- (1,000) Amounts paid for licensing agreement (126) (102) Short-term investment -0- (2,000) Proceeds from sale of available-for-sale security 1,449 -0- Deposits 17 (74) Purchase of furniture, fixture and equipment (141) (97) -------- -------- Net cash provided by (used in) investing activities 1,199 (3,273) Effect of exchange rate on changes in cash (53) (269) -------- -------- Net (decrease) increase in cash and cash equivalents (4,261) 695 Cash and cash equivalents at beginning of period 27,063 30,448 -------- -------- Cash and cash equivalents at end of period $ 22,802 $ 31,143 ======== ======== The accompanying notes are an integral part of this statement. -3- OXIGENE, INC. Notes to Condensed Consolidated Financial Statements (Unaudited) June 30, 2001 1. BASIS OF PRESENTATION The accompanying unaudited condensed financial statements have been prepared in accordance with generally accepted accounting principles for interim financial information and with the instructions to Form 10-Q and Article 10 of Regulation S-X. Accordingly, they do not include all of the information and footnotes required by generally accepted accounting principles for complete financial statements. In the opinion of management, all adjustments (consisting of normal recurring accruals) considered necessary for a fair presentation have been included. Operating results for the three months and six months ended June 30, 2001 are not necessarily indicative of the results that may be expected for the year ending December 31, 2001. The condensed consolidated balance sheet at December 31, 2000 has been derived from the audited financial statements at that date but does not include all of the information and footnotes required by generally accepted accounting principles for complete financial statements. For further information, refer to the consolidated financial statements and footnotes thereto included in the Company's annual report on Form 10-K for the year ended December 31, 2000. 2. NET LOSS PER SHARE Basic and diluted net loss per share was calculated in accordance with the provisions of Statement of Financial Accounting Standards No. 128, Earnings Per Share, by dividing the net loss per share by the weighted-average number of shares outstanding, excluding an insignificant number of antidilutive restricted shares. All options and warrants issued by the Company were antidilutive and, accordingly, excluded from the calculation of weighted-average shares. 3. STOCKHOLDERS' EQUITY The market value of the Company's Common Stock at June 30, 2001 was lower than the exercise price of issued SAR's. Accordingly, there was no financial reporting impact for the six months ended June 30, 2001. During the six months ended June 30, 2001, the Company recorded stock-based compensation expense of approximately $105,000 in connection with options issued to non-employees in the prior years. In connection with the write-down and sale of available-for-sale security in March and June 2001, respectively, the Company reclassified from accumulated other comprehensive loss into earnings for the six-month period ended June 30, 2001, all related unrealized holding loss as of December 31, 2000 of approximately $1,451,000. -4- ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS DESCRIPTION OF BUSINESS OXiGENE is an international biopharmaceutical company engaged principally in research into and the development of products for use in the treatment of cancer. The Company's activities initially were directed primarily towards products designed to complement and enhance the clinical efficacy of radiation and chemotherapy, which are the most common and traditional forms of non-surgical cancer treatment. In recent years, however, the Company's efforts have focused on developing products for application as direct cancer treatment agents, particularly vascular targeting agents ("VTA"). Additionally, the Company is investigating whether certain of its developmental-stage products may have a use as anti-inflammatory agents and in other applications such as treating ocular neo-vascularization and skin disorders. OXiGENE has devoted substantially all of its efforts and resources to research and development conducted on its own behalf and through strategic collaborations with clinical institutions and other organizations, particularly the University of Lund (Lund, Sweden), Baylor University (Waco, Texas), the Danish Cancer Society (Aarhus, Denmark), the Gray Laboratory Cancer Research Trust (Middlesex, United Kingdom) and Arizona State University (Tempe, Arizona). Consequently, OXiGENE believes that its research and development expenditures have been somewhat lower than those of other comparable companies. On December 15, 1999, the Company entered into a Research Collaboration and License Agreement with Bristol-Myers Squibb Company ("BMS"), to sub-license the rights to certain patent rights and other know-how and technology to which the Company had an exclusive license (the "Sub-License Agreement"). Pursuant to the terms of the Sub-License Agreement, BMS paid a non-refundable license fee, will reimburse certain expenses incurred by the Company and fund future research to be performed by the Company based on a research program determined by a joint development committee. In addition, BMS will pay additional amounts upon certain milestones being reached and royalties on future net sales of products. On May 17, 2000, the Company entered into a joint venture agreement with Peregrine Pharmaceuticals ("Peregrine") (formerly Techniclone Corporation), forming ARCUS Therapeutics, LLC ("ARCUS") to develop and commercialize VTA technologies. ARCUS retains patent protection over VTA technologies used in the treatment of solid tumors by disrupting the function of the tumor vessels. Under the terms of the agreement, Peregrine will supply its intellectual property to the joint venture, and OXiGENE will provide licenses with respect to its next generation tubulin-binding compounds for use in conjunction with a Peregrine antibody and, based on the development success of the joint venture, will be required to spend up to $20 million to fund the development expenses of ARCUS. Any further funding of the joint venture thereafter would be shared by the partners on an equal basis. In addition, the Company has paid Peregrine an upfront licensing fee of $1 million in cash and purchased $2 million, or 585,009 shares, of Peregrine's common stock, all of which were sold by the end of June 2001 with the Company recording a loss on the sale and write-down of available-for-sale security of approximately $0.6 million for the six months ended June 30, 2001. Under the terms of the joint venture agreement, any sublicensing fees generated within the joint venture will be allocated 75% to Peregrine and 25% to the Company until Peregrine has reached $10 million in sublicense fee revenues. Thereafter, the joint venture partners will share licensing fees on an equal basis. The Company -5- will also be required to pay Peregrine $1 million in cash and purchase an additional $1 million in Peregrine common stock upon the filing of an Investigational New Drug application for the first clinical candidate developed by ARCUS. Furthermore, Peregrine and OXiGENE will share equally any royalty income or profit from the joint venture. In June 1999, the Company entered into a research collaboration agreement with Active Biotech of Sweden to explore the use of OXiGENE's benzamide and nicotinamide technology (the benzamide technology also being the platform technology for Declopramide) in the treatment of inflammatory diseases. Under the agreement, Active Biotech will evaluate the technology's potential as a treatment for inflammatory diseases. Active Biotech will conduct research with an option to jointly develop anti-inflammatory drug candidates with OXiGENE upon successful completion of the initial research. The Company completed the sale of its Nicoplex and Thiol test products to CampaMed LLC ("CampaMed") on July 2, 2001. Under the terms of the agreement, CampaMed will provide up to $3.3 million in future installment payments based upon sales of the products. In addition, OXiGENE was granted a 10% equity position in CampaMed. During the second quarter of 2001, the Company completed the transition of its scientific, administrative and financial functions to its Watertown, Massachusetts offices. As part of the move, OXiGENE Chairman and CEO, Bjorn Nordenvall, M.D., Ph.D., relocated to Boston, Massachusetts from Sweden. OXiGENE has generated a cumulative net loss of approximately $62.4 million for the period from its inception through June 30, 2001. OXiGENE expects to incur significant additional operating losses over at least the next several years, principally as a result of its continuing clinical trials and anticipated research and development expenditures. The principal source of OXiGENE's working capital has been the proceeds of private and public equity financing and the exercise of warrants and stock options. Prior to entering into the Sub-License Agreement, the Company had no material amount of licensing or other fee income. As of June 30, 2001, OXiGENE had no long-term debt or loans payable except for certain liabilities under the Sub-License Agreement. RESULTS OF OPERATIONS - THREE AND SIX MONTHS ENDED JUNE 30, 2001 AND 2000 REVENUES THREE MONTHS ENDED JUNE 30, 2001 AND 2000 During the three months ended June 30, 2001 and 2000, the Company had licensing revenue of approximately $0.5 million and approximately $0.4 million, respectively, and approximately $0.2 million and approximately $0.5 million in interest income, respectively. SIX MONTHS ENDED JUNE 30, 2001 AND 2000 For the six months ended June 30, 2001 and 2000, the Company had licensing revenue of approximately $1.2 million and approximately $0.9 million, respectively, and approximately $0.5 million and approximately $1.0 million in interest income, respectively. The approximate $0.3 million increase in licensing revenue between June 30, 2000 and 2001 is due to the BMS Sub-License Agreement, under which approximately $1.0 million of research and development expenses in the six months ended June 30, 2001, compared to approximately $0.6 million in the respective period in 2000, were recoverable and, accordingly, classified as licensing revenue and costs relating to licensing revenue. -6- EXPENSES THREE MONTHS ENDED JUNE 30, 2001 AND 2000 Total expenses for the three months ended June 30, 2001 amounted to approximately $4.4 million, compared to approximately $2.7 million for the comparable 2000 period. Research and development expenses increased to approximately $2.0 million from approximately $1.8 million for the comparable 2000 period. The Company recorded a loss on the sale of available-for-sale security totaling approximately $0.5 million for the three months ended June 30, 2001 related to Peregrine stock previously purchased pursuant to the Company's joint venture agreement with Peregrine. No sales of Peregrine stock were made in the comparable 2000 period. General and administrative expenses for the three months ended June 30, 2001 increased to approximately $1.5 million from approximately $0.6 million for the comparable 2000 period. The higher general and administrative expenses related to higher costs associated with the Company's new corporate headquarters in Watertown, Massachusetts following the transfer of functions from the Company's Swedish offices and non-recurring administrative and advisory expenses. SIX MONTHS ENDED JUNE 30, 2001 AND 2000 Operating expenses for the six months ended June 30, 2001 and 2000 were approximately $7.6 million and approximately $6.4 million, respectively. The increase in total expenses is primarily attributable to higher general and administrative costs associated with the Company's new corporate headquarters in Watertown, Massachusetts following the transfer of functions from the Company's Swedish offices and a loss on the sale and write-down of available-for-sale security of Peregrine of approximately $0.6 million. Research and development expenses for the six-month period ended June 30, 2001 decreased to approximately $3.3 million from approximately $4.3 million for the comparable 2000 period. The costs associated with the Phase I clinical trials for CA4P and Declopramide were significantly reduced for the six-month period ended June 30, 2001 as compared to the same period in 2000. The Company records non-cash charges related to the stock appreciation rights ("SARs") previously granted by the Company to certain clinical investigators and consultants and non-qualified stock options ("NQSOs") granted to certain non-employee consultants and advisory board members. Because the market value of the Company's Common Stock at June 30, 2001 was lower than the SARs' exercise price, there were no charges related to SARs during the six months ended June 30, 2001. Similarly, because the market value of the Company's Common Stock at June 30, 2000 was lower than the market value on December 31, 1999, the charge previously recorded for financial reporting purposes decreased by approximately $0.1 million for the six months ended June 30, 2000. During the six months ended June 30, 2001 and 2000, the Company recorded approximately $0.1 million and approximately $0.3 million, respectively, of research and development expenses related to the fair value of the NQSOs vested during the respective period. Without giving effect to the charges related to SARs or NQSOs, research and development expenses for the six months ended June 30, 2001 decreased by approximately $1.0 million, compared to the comparable 2000 period. Generally, the Company makes payments to its clinical investigators if and when certain predetermined milestones in its clinical trials are reached, rather than on a fixed quarterly or monthly basis. As a result of the foregoing and the existence of outstanding SARs and NQSOs, research and development expenses have -7- fluctuated, and are expected to continue to fluctuate, from quarter to quarter. General and administrative expenses for the six-month period ended June 30, 2001 amounted to approximately $2.7 million compared to approximately $1.5 million for the comparable 2000 period. The higher general and administrative expenses related to higher costs associated with the Company's new corporate headquarters in Watertown, Massachusetts following the transfer of functions from the Company's Swedish offices and non-recurring administrative and advisory expenses. LIQUIDITY AND CAPITAL RESOURCES OXiGENE has experienced net losses and negative cash flow from operations each year since its inception, except for the year ended December 31, 2000, and, as of June 30, 2001, had an accumulated deficit of approximately $62.4 million. The Company expects to incur substantial additional expenses, resulting in significant losses, over at least the next several years due to, among other factors, its continuing clinical trials and anticipated research and development activities. To date, the Company has financed its operations principally through net proceeds it has received from private and public equity financing and the exercise of warrants and stock options. The Company had cash and cash equivalents of approximately $22.8 million at June 30, 2001, compared to approximately $27.1 million at December 31, 2000. The decrease in cash and cash equivalents of approximately $4.3 million was primarily attributable to the funding of the basic research programs associated with the next generation of tubulin binding vascular targeting agents and costs associated with ARCUS for the development of antibody VTA's. OXiGENE's policy is to contain its fixed expenditures by maintaining a relatively small number of employees and relying as much as possible on outside services for its research, development, preclinical testing and clinical trials. The Company makes quarterly payments to the University of Lund, Lund, Sweden, and Baylor University, Waco, TX, for pre-clinical research. The Company anticipates that its cash and cash equivalents as of June 30, 2001, should be sufficient to satisfy the Company's projected cash requirements as of that date for the foreseeable future. However, working capital and capital requirements may vary materially from those now planned due to numerous factors including, but not limited to, the progress with preclinical testing and clinical trials; progress of the Company's research and development programs; the time and costs required to obtain regulatory approvals; the resources the Company devotes to manufacturing methods and advanced technologies; the ability of the Company to obtain collaborative or licensing arrangements; the costs of filing, prosecuting and, if necessary, enforcing patent claims; the cost of commercialization activities and arrangements; and the demand for its products if and when approved. The Company anticipates that it will have to seek substantial additional private or public financing or enter into collaborative arrangements with one or more third parties to complete the development of any products or bring products to market. There can be no assurance that additional financing will be available on acceptable terms, if at all. The Company had no material commitments for capital expenditures as of June 30, 2001. TAX MATTERS As of December 31, 2000, the Company had net operating loss carryforwards of approximately $76.8 million for U.S. and foreign income tax purposes, of which approximately $45.9 million expires for U.S. purposes through 2020. The -8- utilization of approximately $2.5 million of such U.S. net operating losses is subject to an annual limitation, pursuant to Section 382 of the U.S. Internal Revenue Code, of approximately $350,000. ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISKS The Company's cash and cash equivalents are maintained primarily in U.S. dollar accounts and amounts payable for research and development to research organizations are contracted in U.S. dollars. Accordingly, the Company's exposure to foreign currency risk is limited because its transactions are primarily based in U.S. dollars. The Company does not have any other exposure to market risk. The Company will develop policies and procedures to manage market risk in the future as circumstances may require. -9- PART II - OTHER INFORMATION ITEM 1. LEGAL PROCEEDINGS There are no material suits or claims pending or, to the best of the Company's knowledge, threatened against the Company. ITEM 2. CHANGES IN SECURITIES AND USE OF PROCEEDS None. ITEM 3. DEFAULTS UPON SENIOR SECURITIES None. ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS On June 11, 2001, the Company held its Annual Meeting of Stockholders (the "Meeting") at the Company's principal offices in Watertown, Massachusetts. On April 12, 2001, the record date, there were 11,373,593 shares of outstanding Common Stock of the Company that could be voted at the Meeting. A total of 10,401,175 shares were present, in person or by proxy, and voted at the Meeting. At the Meeting, all nominees for director, Professor Marvin H. Caruthers, Joel-Tomas Citron, Gerald A. Eppner, Michael Ionata, Arthur B. Laffer, Dr. Bjorn Nordenvall, Dr. Ronald W. Pero and Per-Olof Soderberg, were elected as follows: - ----------------------------------------------------------------------------------------- Name of Director Votes For Votes Against - ----------------------------------------------------------------------------------------- Number of Percentage of Number of Percentage of Shares Vote Shares Vote - ----------------------------------------------------------------------------------------- Marvin H. Caruthers 10,360,643 99.61% 40,532 0.39% - ----------------------------------------------------------------------------------------- Joel-Tomas Citron 10,360,643 99.61% 40,532 0.39% - ----------------------------------------------------------------------------------------- Gerald A. Eppner 10,360,643 99.61% 40,532 0.39% - ----------------------------------------------------------------------------------------- Michael Ionata 10,360,643 99.61% 40,532 0.39% - ----------------------------------------------------------------------------------------- Arthur B. Laffer 10,360,643 99.61% 40,532 0.39% - ----------------------------------------------------------------------------------------- Bjorn Nordenvall 10,359,343 99.60% 41,832 0.40% - ----------------------------------------------------------------------------------------- Ronald W. Pero 10,360,643 99.61% 40,532 0.39% - ----------------------------------------------------------------------------------------- Per-Olof Soderberg 10,360,643 99.61% 40,532 0.39% - ----------------------------------------------------------------------------------------- At the Meeting, the Company's stockholders also ratified the appointment of Ernst & Young LLP as the Company's independent auditors for the year ending December 31, 2001, with 10,370,792 votes or 99.71% cast in favor, 6,062 votes against, and 24,321 abstentions. -10- ITEM 5. OTHER INFORMATION Not applicable. ITEM 6. EXHIBITS AND REPORTS ON FORM 8-K (a) Exhibits. None. (b) Reports on Form 8-K. The Company filed no reports on Form 8-K during the second quarter of 2001. -11- SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized. OXiGENE, INC. (Registrant) Date: August 14, 2001 By: /s/ Frederick Driscoll ------------------------------------- Frederick Driscoll, President of Operations and Finance (Principal Financial Officer) -12-