EXHIBIT 32.1

                    CERTIFICATION OF CHIEF EXECUTIVE OFFICER
                       PURSUANT TO 18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly Report of American Home Mortgage Investment
Corp. (the "Registrant") on Form 10-Q for the quarter ended September 30, 2005,
as filed with the Securities and Exchange Commission on the date hereof (the
"Report"), I, Michael Strauss, Chairman of the Board, Chief Executive Officer
and President of the Registrant, certify, pursuant to 18 U.S.C. Section 1350, as
adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, to the best
of my knowledge, that:

           (1)  The Report fully complies with the requirements of Section 13(a)
                or 15(d) of the Securities Exchange Act of 1934; and

           (2)  The information contained in the Report fairly presents, in all
                material respects, the financial condition and results of
                operations of the Registrant.

November 9, 2005

                                    /s/ Michael Strauss
                               -------------------------------------
                               Michael Strauss
                               Chairman, Chief Executive Officer
                               and President