SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                               __________________

                                    FORM 8-K

              CURRENT REPORT PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934


        DATE OF REPORT (DATE OF EARLIEST EVENT REPORTED) August 30, 2002


                           UNIGENE LABORATORIES, INC.
             (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)


          DELAWARE                     0-16005                    22-2328609
(STATE OR OTHER JURISDICTION        (COMMISSION               (I.R.S. EMPLOYER
     OF INCORPORATION)               FILE NUMBER)            IDENTIFICATION NO.)

                              110 LITTLE FALLS ROAD
                           FAIRFIELD, NEW JERSEY 07004
               (ADDRESS OF PRINCIPAL EXECUTIVE OFFICES) (ZIP CODE)

REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE      (973) 882-0860





ITEM 4.     CHANGES IN REGISTRANT'S CERTIFYING ACCOUNTANT

     On August 30, 2002, Unigene Laboratories, Inc. (the "Company"), decided to
appoint Grant Thornton LLP as its new independent auditor. The Company's Audit
Committee and Board of Directors participated in and approved the decision to
appoint Grant Thornton.

     During the two most recent fiscal years ended December 31, 2001 and 2000
and through the date of this Form 8-K, neither the Company, nor anyone on its
behalf, has consulted with Grant Thornton regarding either the application of
accounting principles to a specified transaction, either completed or proposed,
or the type of audit opinion that might be rendered on the Company's financial
statements, or any matters or reportable events described under Item
304(a)(2)(i) and (ii) of Regulation S-K.





                                   SIGNATURES

     Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                                     UNIGENE LABORATORIES, INC.

                                                     /s/  Warren P. Levy
                                                     ---------------------------
Date:    September 20, 2002                          By: Warren P. Levy
                                                     President
                                                     (Chief Executive Officer)