STOCK PURCHASE AGREEMENT

                  This Stock Purchase Agreement (the  "Agreement"),  dated as of
July 15, 1997,  is entered  into by and between  Unigene  Laboratories,  Inc., a
Delaware corporation ("Unigene"), and Warner-Lambert Company, a Delaware
corporation ("Purchaser").

                              W I T N E S S E T H: 

                  WHEREAS,  Unigene and  Purchaser  simultaneously  herewith are
entering  into a License  Agreement,  dated as of July 15,  1997  (the  "License
Agreement"),  pursuant to which Unigene has licensed to Purchaser  rights to use
certain of Unigene's proprietary technology; and

                  WHEREAS,  Unigene in connection  therewith wishes to issue and
sell to Purchaser,  and Purchaser wishes to purchase from Unigene,  on the terms
and  conditions set forth in this  Agreement,  the number of shares of Unigene's
common  stock,  par value $.01 per share (the  "Common  Stock"),  determined  in
accordance with the provisions of Section 1.1 hereof.

                  NOW THEREFORE,  in consideration of the foregoing premises and
the mutual covenants contained in this Agreement and for other good and valuable
consideration, the receipt and sufficiency of which are hereby acknowledged, the
parties hereto, intending to be legally bound, hereby agree as follows:


                                    ARTICLE I
                           PURCHASE AND SALE OF STOCK 

         1.1 Purchase of Stock.  On the terms and  conditions  set forth in this
Agreement,  Unigene agrees to issue and sell to Purchaser,  and Purchaser agrees
to purchase  from  Unigene,  at a purchase  price of  $3,000,000,  the number of
shares of Common  Stock  that is equal to the total  obtained  by  dividing  (i)
$3,000,000,  by (ii) the average of the closing  sale prices of the Common Stock
as  reported  by the  Nasdaq  Stock  Market for each  trading  day during the 30
calendar days  preceding  and the 30 calendar days  beginning on the date of the
first  public  announcement  of  the  entry  by the  parties  into  the  License
Agreement;  provided that if the calculation described in this Section 1.1 would
create a fractional  share,  such fractional  share shall be disregarded and the
number of  shares of Common  Stock  purchased  and sold  hereunder  shall be the
number of whole shares.

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         1.2  Deliveries.  On the  date  of the  execution  of  this  Agreement,
Purchaser  shall deliver to Unigene,  by wire transfer of immediately  available
funds to such bank account as shall be designated by Unigene, an amount equal to
$3,000,000.  Promptly  following the conclusion of the 60-day period referred to
in  Section  1.1,  Unigene  shall  deliver  to  Purchaser  a  stock  certificate
registered in the name of Purchaser  representing the number of shares of Common
Stock determined in accordance with Section 1.1 hereof.


                                   ARTICLE II
                         REPRESENTATIONS AND WARRANTIES

         2.1 Representations  and Warranties of Unigene.  Unigene represents and
warrants to Purchaser that, as of the date hereof:

                  (a) Organization, Good Standing and Qualification.  Unigene is
duly  incorporated,  validly existing and in good standing under the laws of the
State of Delaware.

                  (b)  Authorization.  Unigene has the corporate power necessary
to execute, deliver and perform this Agreement, and such execution, delivery and
performance  have been duly authorized by all necessary  corporate action on the
part of Unigene.  This Agreement has been duly executed and delivered by Unigene
and constitutes a legal,  valid and binding  obligation of Unigene,  enforceable
against Unigene in accordance with its terms.

                  (c) No Violations. The execution,  delivery and performance of
this  Agreement by Unigene  does not and will not: (i) violate any  provision of
Unigene's  Certificate  of  Incorporation  or By-laws;  (ii) violate,  breach or
constitute a default (or an event or condition that with the giving of notice or
the  passage of time or both could  give rise to a default)  under any  material
contract or agreement to which  Unigene is a party or by which Unigene is bound;
(iii) result in the creation of a lien, security interest, charge or encumbrance
on any  property or assets of Unigene;  (iv)  except for such  filings  with the
Securities and Exchange Commission or any state securities  commission as may be
required to perfect a private  placement or limited  offering  exemption for the
sale of the  shares of Common  Stock,  require  the  authorization,  consent  or
approval of, or filing with,  any court or any  administrative  or  governmental
body  pursuant  to any law,  statute,  rule or  regulation  to which  Unigene is
subject  or any order,  judgement  or decree by which  Unigene is bound;  or (v)
constitute a default  under or violate any law,  statute,  rule or regulation to
which Unigene is subject or any

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order, judgement or decree of any court,  administrative agency or arbitrator by
which Unigene is bound.

                  (d) Litigation.  There is no suit,  action or other proceeding
of any nature pending or, to the best knowledge of Unigene,  threatened  against
Unigene before any court or other  governmental  agency or  instrumentally  that
challenges or seeks to prevent the consummation of the transactions contemplated
by this Agreement.

                  (e) Valid Issuance of Common Stock. The shares of Common Stock
to be issued  pursuant to this  Agreement  have been duly  authorized  and, upon
issuance in accordance with the terms of this Agreement, will be validly issued,
fully paid and nonassessable.

                  (f)  Capitalization.  (a)  The  authorized  capital  stock  of
Unigene  consists of 60,000,000  shares of Common Stock, of which, as of May 15,
1997,  (i) 37,264,165  shares were  outstanding  and (ii) 7,434,719  shares were
reserved for issuance  either upon the  conversion  of  outstanding  convertible
securities or upon the exercise of  outstanding  options and warrants.  There is
only one class of Common Stock.

                  (g)   Securities   Laws.   Assuming   the   accuracy   of  the
representations  and warranties of Purchaser  contained in this  Agreement,  the
sale of the shares of Common  Stock to be issued  pursuant  to the terms of this
Agreement will be exempt from registration  under the Securities Act of 1933, as
amended (the "Securities Act").

         2.2 Representations and Warranties of Purchaser.  Purchaser  represents
and warrants to Unigene that, as of the date hereof:

                  (a) Organization,  Good Standing and Qualification.  Purchaser
is duly  incorporated,  validly  existing and in good standing under the laws of
the State of Delaware.

                  (b) Authorization. Purchaser has the corporate power necessary
to execute, deliver and perform this Agreement, and such execution, delivery and
performance  have been duly authorized by all necessary  corporate action on the
part of  Purchaser.  This  Agreement  has been duly  executed  and  delivered by
Purchaser and  constitutes a legal,  valid and binding  obligation of Purchaser,
enforceable against Purchaser in accordance with its terms.

                  (c) No Violations. The execution,  delivery and performance of
this Agreement by Purchaser does not and will

                                        4

not: (i) violate any provision of Purchaser's  Certificate of  Incorporation  or
By-laws; (ii) violate,  breach or constitute a default (or an event or condition
that with the giving of notice or the passage of time or both could give rise to
a default)  under any material  contract or  agreement  to which  Purchaser is a
party or by which  Purchaser  is bound;  (iii) result in the creation of a lien,
security interest, change or encumbrance on any property or assets of Purchaser,
(iv) require the  authorization,  consent or approval  of, or filing  with,  any
court or any  administrative  or governmental body pursuant to any law, statute,
rule or  regulation  to which  Purchaser  is subject or any order,  judgement or
decree  by which  Purchaser  is bound;  or (iv)  constitute  a default  under or
violate any law,  statute,  rule or regulation to which  Purchaser is subject or
any order, judgement or decree of any court, administrative agency or arbitrator
by which Purchaser is bound.

                  (d) Litigation.  There is no suit,  action or other proceeding
of any nature pending or, to the best knowledge of Purchaser, threatened against
Purchaser before any court or other governmental  agency or instrumentally  that
challenges or seeks to prevent the consummation of the transactions contemplated
by this Agreement.

                  (e) Purchase Entirely For Own Account;  Investment Experience;
Access to  Information.  Purchaser is purchasing  the shares of Common Stock for
its own account without a view to any  distribution  thereof in violation of the
Securities  Act, or any  applicable  state  securities  laws,  and  Purchaser is
experienced  in  evaluation  and making  investments  of this type,  and has had
access  to,  and  has  received,  all  information  concerning  Unigene  that it
reasonably  has  required to  evaluate  its  investment  in the shares of Common
Stock.

                  (f) Accredited Investor. Purchaser is financially able to bear
the risks of an investment  in the shares of Common Stock and is an  "accredited
investor"  within the meaning of Rule 501 of  Regulation D under the  Securities
Act.  Purchaser  understands and  acknowledges  that an investment in the Common
Stock is speculative and involves a high degree of risk.

                  (g) Restricted Securities. Purchaser acknowledges that Unigene
is selling the shares of Common Stock pursuant to an exemption from registration
under Section 4(2) of the Securities Act in reliance on the  representations and
warranties of Purchaser  herein,  and agrees that the shares of Common Stock may
be offered,  sold,  pledged or otherwise  transferred  by Purchaser  only if the
transaction is registered under the Securities Act or is effected pursuant to an
exemption from such registration requirements.

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                  (h) Legends.  Purchaser agrees that the following legend shall
be placed on the  certificate(s)  evidencing  the shares of Common  Stock for so
long as the shares remain "restricted securities" within the meaning of Rule 144
under the Securities Act:

                  "The  shares  represented  by this  certificate  have not been
                  registered under the Securities Act of 1933, as amended.  Such
                  shares  have  been  acquired  for  investment  and  may not be
                  offered,  sold,  pledged or otherwise  transferred,  except in
                  compliance with the  registration  requirements of said Act or
                  pursuant to an exemption therefrom."

Purchaser  understands  that,  while such legend  remains on the  certificate(s)
evidencing the shares of Common Stock, Unigene will direct its transfer agent to
maintain "stop transfer"  procedures with respect to the shares.  Unigene agrees
that,  when the Shares of Common Stock become  eligible for sale pursuant to the
provisions  of Rule 144(k)  under the  Securities  Act,  Unigene will direct the
transfer  agent to remove  the  above-referenced  legend  from any  certificates
tendered by Purchaser for such purpose.


                                   ARTICLE III
                                  MISCELLANEOUS

         3.1  Expenses.  All legal and other  costs  and  expenses  incurred  in
connection with this Agreement and the transactions contemplated hereby shall be
paid by the party incurring such expenses.

         3.2  Amendments;  Waivers.  Any  provisions  of this  Agreement  may be
amended  or waived by the  parties  hereto if, but only if,  such  amendment  or
waiver is in writing and is signed by both parties  hereto.  No failure or delay
by any party hereto in exercising any right, power or privilege  hereunder shall
operate as a waiver  thereof  nor shall any single or  partial  exercise  of any
right,  power or  privilege  hereunder  preclude  any other or further  exercise
thereof or the exercise of any other right, power or privilege.

         3.3 No Third Party Beneficiaries. This Agreement is made solely for the
benefit  of the  parties  hereto  and shall not  confer  any rights on any other
person.

         3.4 Notices. Any notice, demand,  request,  consent,  approval or other
communication  that is required or  permitted  to be given or made by a party to
the other pursuant to any provision of this Agreement  shall be given or made in
writing

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and shall be served  personally  or shall be sent by facsimile  transmission  or
overnight delivery addressed to the party as follows:

         If to Unigene:

                  Unigene Laboratories, Inc.
                  110 Little Falls Road
                  Fairfield, NJ 07004
                  Attention: Chief Executive Officer
                  Telephone: (973) 882-0860
                  Fax: (973) 227-6088

         If to Purchaser:

                  Warner-Lambert Company
                  201 Tabor Road
                  Morris Plains, New Jersey 07950
                  Attn:  President, Pharmaceutical Sector
                  Fax: (973) 540-4009

         With a copy to:

                  Warner-Lambert Company
                  201 Tabor Road
                  Morris Plains, New Jersey 07950
                  Attn:  Vice President and General Counsel
                  Fax: (973) 540-3927


or to such other  address as either party may from time to time advise the other
party hereto by notice in writing. Every such notice so given shall be deemed to
be received only upon delivery to the party to be charged with notice.

         3.5 Severability. Should any provision of this Agreement for any reason
be  declared  invalid or  unenforceable,  such  invalidity  shall not affect the
validity or  enforceability  of any of the other  provisions of this  Agreement,
which shall remain in full force and effect, and the application of such invalid
or unenforceable  provision to persons or  circumstances  other than those as to
which it is held  invalid or  unenforceable  shall be valid and  enforced to the
fullest extent permitted by law.

         3.6  Headings.  The  descriptive  headings of the several  Articles and
Sections of this Agreement are inserted for convenience  only, do not constitute
a part of this  Agreement  and  shall  not  affect  in any  way the  meaning  or
interpretation of this Agreement.

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         3.7 Applicable Law. The validity and  interpretation of this Agreement,
and the performance by the parties of their  respective  obligations  hereunder,
shall be  governed by the laws of the State of New York,  without  regard to the
choice of law provisions thereof.

         3.8  Counterparts.  This Agreement may be executed in two counterparts,
each of which  shall be deemed an  original,  and it shall not be  necessary  in
making  proof  of this  Agreement  to  produce  or  account  for  more  than one
counterpart signed by the party to be charged thereby.

         3.9 Entire Agreement.  This Agreement  contains the entire agreement of
the parties hereto with respect to the subject matter hereof, and supersedes all
previous agreements and understandings  between the parties with respect to such
matters.

         3.10  Successors and Assigns.  This Agreement shall be binding upon and
inure to the benefit of the parties hereto and their  respective  successors and
permitted assigns and transferees.  This Agreement may not be assigned by either
party without the prior written consent of the other;  provided,  however,  that
either  party may  assign its rights and  delegate  its duties  hereunder  to an
Affiliate  thereof without  obtaining such consent,  provided that the assigning
party agrees to remain  primarily (and not secondarily or  derivatively)  liable
for the full and timely  performance  by such  Affiliate of all its  obligations
hereunder.


                  IN WITNESS  WHEREOF,  the  parties  hereto  have  caused  this
Agreement to be executed as of the date first above written.

                                                     UNIGENE LABORATORIES, INC.


                                                     By: /s/ WARREN P. LEVY
                                                        -------------------
                                                        Warren P. Levy
                                                        President


                                                     WARNER-LAMBERT COMPANY


                                                     By: /s/ MAURICE RENSHAW
                                                        --------------------
                                                        Maurice Renshaw
                                                        Vice President and
                                                        President, Parke-Davis,
                                                        U.S. and Mexico