EMPLOYMENT AGREEMENT

THIS AGREEMENT,  dated as of January 1, 1998, is made by and between  NEUROCRINE
BIOSCIENCES. INC., a Delaware corporation (hereinafter the "Company"), and BRUCE
CAMPBELL, Ph.D. (hereinafter "Executive").

                                 R E C I T A L S

         WHEREAS,  the Company and Executive wish to set forth in this Agreement
the terms and conditions  under which Executive is to be employed by the Company
on and after the date hereof; and

         NOW,  THEREFORE,  the Company and Executive,  in  consideration  of the
mutual promises set forth herein, agree as follows:

                                    ARTICLE 1

                                TERM OF AGREEMENT

         1.1 Commencement Date. Executive's fulltime employment with the Company
under this Agreement shall commence as of January 1, 1998 ("Commencement  Date")
and this  Agreement  shall  expire  after a period of three  (3) years  from the
Commencement Date, unless terminated earlier pursuant to Article 6.

         1.2 Renewal. The term of this Agreement shall be automatically  renewed
for  successive,  additional  three (3) year terms unless either party  delivers
written  notice to the other at least  ninety (90) days prior to the  expiration
date of this  Agreement of an intention to terminate  this Agreement or to renew
it for a term of less than  three  (3) years but not less than (1) year.  If the
term of this Agreement is renewed for a term of less than three (3) years,  then
thereafter  the  term of this  Agreement  shall  be  automatically  renewed  for
successive,  additional  identical  terms unless either party delivers a written
notice to the other at least ninety (90) days prior to a terminate  date of this
Agreement  of an  intention  to  terminate  this  Agreement or to renew it for a
different term of not less than one (1) year.

                                    ARTICLE 2

                                EMPLOYMENT DUTIES

         2.1  Title/Responsibilities.  Executive hereby accepts  employment with
the Company  pursuant to the terms and conditions  hereof.  Executive  agrees to
serve the Company in the  position of Vice  President -  Development.  Executive
shall have the powers and duties commensurate with such position,  including but
not limited to hiring personnel necessary to carry out the  responsibilities for
such position as set forth in the annual  business plan approved by the Board of
Directors.

         2.2 Full Time  Attention.  Executive  shall devote his best efforts and
his  full  business  time  and  attention  to the  performance  of the  services
customarily  incident to such office and to such other services as the President
or Board may reasonably request.

         2.3 Other  Activities.  Except  upon the prior  written  consent of the
President & Chief  Executive  Officer,  Executive shall not during the period of
employment  engage,  directly  or  indirectly,  in any other  business  activity
(whether or not pursued for pecuniary  advantage)  that is or may be competitive
with, or that might place him in a competing  position to that of the Company or
any other  corporation  or entity  that  directly  or  indirectly  controls,  is
controlled  by, or is under  common  control  with the Company  (an  "Affiliated
Company"),  provided  that  Executive  may own less than two percent (2%) of the
outstanding securities of any such publicly traded competing corporation.


                                    ARTICLE 3

                                  COMPENSATION

         3.1 Base  Salary.  Executive  shall  receive a Base Salary at an annual
rate of two hundred thousand dollars  (200,000),  payable  semi-monthly in equal
installments  in accordance  with the Company's  normal payroll  practices.  The
Company's  Board of Directors  shall provide  Executive with annual  performance
reviews,  and, thereafter,  Executive shall be entitled to such increase in Base
Salary as the Board of  Directors  may from time to time  establish  in its sole
discretion. In addition, upon signing this Agreement,  Executive will receive an
initial bonus of twenty thousand dollars ($20,000).

         3.2 Incentive  Bonus. In addition to any other bonus Executive shall be
awarded by the Company's  Board of Directors,  the Company shall pay Executive a
bonus payment of up to fifty  thousand  dollars  ($50,000)  annually  based upon
achievement  by the Company  against six to eight impact  goals  approved by the
Board of  Directors  annually.  Such goals  shall be set forth in writing by the
Board within ninety (90) days after the start of the Company's fiscal year and a
copy shall be delivered to Executive  within fifteen (15) days  thereafter.  The
Board of  Directors  shall,  in their sole  discretion,  determine  whether such
impact goals have been obtained.

         3.3  Equity.   Executive  has  previously  entered  into  a  Consulting
Agreement  ("Consulting  Agreement")  with the Company dated  September 9, 1997.
Pursuant to the Consulting  Agreement,  Executive has received a stock option to
purchase one hundred  twenty-five  thousand  (125,000)  shares of the  Company's
common stock with an exercise price of six dollars and ninety-one  cents ($6.91)
per  share,  representing  the  Company's  market  price  at the  time of  Board
approval.  Such option shall continue to vest in accordance  with the Consulting
Agreement and in accordance with the terms of the Company's 1992 Incentive Stock
Incentive  Plan, as amended.  Upon execution of this  Agreement,  the Consulting
Agreement will terminate.

         3.3  Withholdings.  All  compensation and benefits payable to Executive
hereunder and the Agreement  shall be subject to all federal,  state,  local and
other withholdings and similar taxes and payments required by applicable law.

                                    ARTICLE 4

                     EXPENSE ALLOWANCES AND FRINGE BENEFITS

         4.1 Vacation.  Executive  shall be entitled to the greater of three (3)
weeks of annual paid  vacation  or the amount of annual  paid  vacation to which
Executive may become  entitled under the terms of Company's  vacation policy for
employees during the term of this Agreement.

         4.2 Benefits. During the term of this Agreement, the Company shall also
provide Executive with the usual health insurance benefits it generally provides
to its other  senior  management  employees.  As Executive  becomes  eligible in
accordance with criteria to be adopted by the Company, the Company shall provide
Executive  with the right to  participate  in and to receive  benefit from life,
accident, disability, medical, pension, bonus, stock, profit-sharing and savings
plans and similar benefits made available  generally to employees of the Company
as such plans and benefits may be adopted by the Company.  The amount and extent
of benefits to which  Executive  is entitled  shall be governed by the  specific
benefit plan as it may be amended from time to time.

         4.3  Relocation to San Diego, CA. The Executive shall be reimbursed for
reasonable  and customary  relocation  expenses as follows:

     (a)  out of pocket expenses related to selling Executive's existing home in
          the United Kingdom, including customary real estate commissions not to
          exceed one percent (1%) of selling price and associated costs;

     (b)  reasonable  house hunting and up to sixty (60) days  temporary  living
          expenses;

     (c)  customary  closing  costs  associated  with the purchase of a new home
          including  up to one and  one-half  points of the  mortgage  financing
          amount related to the purchase of a new home;

     (d)  reasonable  and  customary  moving  expenses  of  household  goods and
          personal  property  (including  temporary  storage of up the three (3)
          months) to San Diego, CA;

     (e)  up to twenty thousand dollars ($20,000) for  miscellaneous  documented
          relocation expenses,  payable upon the purchase or rental of a home in
          San Diego, CA.

The Company will reimburse the Executive for the incremental increase in federal
and state income taxes  associated with the payment of expenses  associated with
items (a) through (d) above.  In  addition,  the Company  will retain at Company
expense,  for the benefit of Executive,  a tax  specialist  who will provide tax
guidance associated with the Executive's relocation to the United States for the
three tax periods  immediately  following  Executive's  relocation to the United
States.

         4.4 Relocation  Loan: In connection  with the purchase of a home in the
San Diego  area,  the  Company  will  provide to  Executive  a loan of up to two
hundred and fifty thousand dollars  ($250,000)  representing the excess over the
purchase  price  of a home in San  Diego  over  five  hundred  thousand  dollars
($500,000). Such loan will, at the option of the Company, be secured by a second
mortgage deed on the home purchased by Executive.  The principal  balance of the
loan will bear  interest  at a rate of one  percent  per annum  (1.0%  p.a.) and
principal  and  interest  will be payable upon the first to occur of (i) sale of
the home, (ii) six (6) months following voluntary or involuntary  termination of
Executive's employment with the Company,  (iii) the exercise,  pledge or sale of
all or part of the  stock  options  granted  by  Company  to  Executive  or (iv)
December 31, 1999.

         4.5 Relocation to the Untied Kingdom:  Upon  termination of Executive's
employment  with the Company,  the Company will  reimburse  Executive  for costs
associated with  relocation back to the United Kingdom  including (i) the lesser
of  customary  closing  costs and fees (not to exceed  six  percent  (6%) of the
selling  price)  related to the sale by Executive of the first home in San Diego
owned by Executive during the term of this Agreement or customary  closing costs
and fees (not to exceed six percent  (6%) of the selling  price)  related to the
sale of  Executive's  home in San  Diego  on the  date  of  termination  of this
Agreement, (ii) documented reasonable and customary moving expenses of household
goods and personal  property not to exceed in the aggregate ten thousand dollars
($10,000).  The foregoing provision shall not apply in the event (i) at the time
of relocation,  Executive has accepted  employment with another company or it is
Executive's intention to do so within a period of six (6) months, (ii) Executive
has not completed  four (4) full years of employment at the Company  (other than
by reason of the failure of the Company to renew the term of this  Agreement) or
(iii)  termination  of Executive's  employment  with the Company is for Cause as
defined in paragraph 6.3 below.

         4.6  Other  Relocation  Expenses.  The  Company  will  provide  to  the
Executive's wife, mother and  mother-in-law,  one round trip coach ticket to and
from San Diego and London. The Company will arrange for a Business Class upgrade
for these tickets.

         4.7 Business Expense Reimbursement.  During the term of this Agreement,
Executive shall be entitled to receive proper  reimbursement  for all reasonable
out-of-pocket  expenses  incurred by him (in  accordance  with the  policies and
procedures  established  by the Company for its senior  executive  officers)  in
performing  services  hereunder.  Executive  agrees to  furnish  to the  Company
adequate  records  and other  documentary  evidence  of such  expense  for which
Executive seeks  reimbursement.  Such expenses shall be reimbursed and accounted
for under the policies and  procedure  established  by the Company and the Audit
Committee of the Board of Directors.

                                    ARTICLE 5

                                 CONFIDENTIALITY

         5.1 Proprietary Information.  Executive represents and warrants that he
has  previously  executed and  delivered to the Company the  Company's  standard
Proprietary  Information  and  Inventions  Agreement in form  acceptable  to the
Company's counsel.

         5.2 Return of Property. All documents,  records,  apparatus,  equipment
and other  physical  property  which is furnished to or obtained by Executive in
the  course of his  employment  with the  Company  shall be and  remain the sole
property of the Company.  Executive  agrees that,  upon the  termination  of his
employment,  he shall  return all such  property  (whether or not it pertains to
Proprietary Information as defined in the Proprietary Information and Inventions
Agreement), and agrees not to make or retain copies,  reproductions or summaries
of any such property.

                                    ARTICLE 6

                                   TERMINATION

         6.1 By Death.  The period of employment  shall terminate  automatically
upon the death of Executive. In such event, the Company shall pay to Executive's
beneficiaries  or his estate,  as the case may be, any accrued Base Salary,  any
bonus compensation to the extent earned, any vested deferred compensation (other
than  pension  plan  or  profit-sharing  plan  benefits  which  will  be paid in
accordance  with the  applicable  plan),  any  benefits  under  any plans of the
Company in which  Executive is a participant  to the full extent of  Executive's
rights under such plans, any accrued  vacation pay and any appropriate  business
expenses incurred by Executive in connection with his duties  hereunder,  all to
the  date of  termination  (collectively  Accrued  Compensation),  but no  other
compensation  or  reimbursement  of any  kind,  including,  without  limitation,
severance  compensation,  and thereafter,  the Company's  obligations  hereunder
shall terminate.

         6.2 By Disability.  If Executive is prevented from properly  performing
his duties hereunder by reason of any physical or mental incapacity for a period
of 120 consecutive days, or for 180 days in the aggregate in any 365-day period,
then, to the extent  permitted by law, the Company may terminate the  employment
of Executive at such time. In such event, the Company shall pay to Executive all
Accrued  Compensation,  and shall  continue to pay to Executive  the Base Salary
until such time (but not more than 90 days following termination),  as Executive
shall  become  entitled  to  receive  disability  insurance  payments  under the
disability insurance policy maintained by the Company, but no other compensation
or  reimbursement  of  any  kind,   including  without   limitation,   severance
compensation,   and  thereafter  the  Company's   obligations   hereunder  shall
terminate.  Nothing in this Section  shall affect  Executive's  rights under any
disability plan in which he is a participant.

         6.3 By Company for Cause.  The Company may  terminate  the  Executive's
employment for Cause (as defined  below)  without  liability at any time with or
without advance notice to Executive. The Company shall pay Executive all Accrued
Compensation,  but no other compensation or reimbursement of any kind, including
without  limitation,   severance  compensation,  and  thereafter  the  Company's
obligations  hereunder shall terminate.  Termination shall be for "Cause" in the
event of the occurrence of any of the following:  (a) any intentional  action or
intentional  failure to act by Executive which was performed in bad faith and to
the material detriment of the Company;  (b) Executive  intentionally  refuses or
intentionally fails to act in accordance with any lawful and proper direction or
order of the Board; (c) Executive  willfully and habitually  neglects the duties
of employment;  or (d) Executive is convicted of a felony crime  involving moral
turpitude, provided that in the event that an of the foregoing events is capable
of being cured, the Company shall provide written notice to Executive describing
the nature of such event and Executive  shall  thereafter have ten (10) business
days to cure such event.

         6.4  Termination  Without Cause. At any time, the Company may terminate
the employment of Executive without liability other than as set forth below, for
any reason not  specified  in Section  6.3  above,  by giving  thirty  (30) days
advance  written  notice  to  Executive.  If the  Company  elects  to  terminate
Executive  pursuant to this Section 6.4, (a) the Company  shall pay to Executive
all Accrued  Compensation  (b) the Company shall continue to pay to Executive as
provided herein Executive's Base Salary over the period equal to nine (9) months
from the date of such termination as severance compensation,  (c) if Executive's
employment  terminates  in the second half of the  Company's  fiscal  year,  the
Company  shall make a lump sum payment to  Executive in an amount equal to a pro
rata portion of the Executive's annual actual cash incentive bonus for Company's
fiscal year preceding the year of  termination  based on the number of completed
months of Executive's employment in the fiscal year divided by nine (9); (d) the
vesting of all outstanding  stock options held by Executive shall be accelerated
so that the amount of shares vested under such option shall equal that number of
shares  which would have been vested if the  Executive  had  continued to render
services  to the Company for nine (9)  continuous  months  after the date of his
termination  of  employment;  and (e) the Company  shall pay all costs which the
Company would otherwise have incurred to maintain all of Executive's  health and
welfare, and retirement benefits (either on the same or substantially equivalent
terms and  conditions) if the Executive had continued to render  services to the
Company for nine (9)  continuous  months  after the date of his  termination  of
employment.  The Company shall have no further  obligations  to Executive  other
than those set forth in the preceding sentence. During the period when such Base
Salary  severance  compensation is being paid to Executive,  Executive shall not
(i) engage, directly or indirectly,  in providing services to any other business
program or project that is competitive  to a program or project being  conducted
by the  Company  or any  Affiliated  Company  at the  time  of  such  employment
termination  (provided  that Executive may own less than two percent (2%) of the
outstanding  securities  of any  publicly  traded  corporation),  or (ii)  hire,
solicit,  or attempt  to solicit on behalf of himself or any other  party or any
employee or exclusive  consultant of the Company. If the Company terminates this
Agreement or the employment of Executive with the Company other than pursuant to
Section 6.1, 6.2 or 6.3, then this section 6.4 shall apply.

         6.5 Constructive Termination A Constructive Termination shall be deemed
to be a termination of employment of Executive without cause pursuant to Section
6.4 For Purposes of this Agreement, a "Constructive  Termination" means that the
Executive  voluntarily  terminates his employment after any of the following are
undertaken without Executive's express written consent:

     (a)  the  assignment to Executive of any duties or  responsibilities  which
          result in any diminution or adverse  change of  Executive's  position,
          status or  circumstances  of  employment;  or any removal of Executive
          from or any failure to re-elect  Executive  to any of such  positions,
          except in connection with the termination of his employment for death,
          disability, retirement, fraud, misappropriation,  embezzlement (or any
          other occurrence which  constitutes  "Cause" under section 6.3) or any
          other  voluntary  termination of employment by Executive  other than a
          Constructive Termination;

     (b)  a  reduction  by the  Company in  Executive's  annual  Base  Salary by
          greater than five percent (5%);

     (c)  a relocation of Executive or the Company's principal executive offices
          if Executive's principal office is at such offices, to a location more
          than forty (40) miles from the  location  at which  Executive  is then
          performing his duties,  except for an opportunity to relocate which is
          accepted by Executive in writing;

     (d)  any material breach by the Company of any provision of this Agreement;
          or

     (e)  any failure by the Company to obtain the  assumption of this Agreement
          by any successor or assign of the Company.

         6.6  Termination  Following  Change  in  Control  In  the  event  of  a
non-renewal  of this  Agreement,  a termination  without Cause or a Constructive
Termination within eighteen (18) months following a Change in Control, Executive
shall receive the same benefits  package as Executive would have received upon a
termination  without Cause (except that the payment of Base Salary shall be made
in the form of a lump sum) and in addition, the vesting of all outstanding stock
options  held by  Executive  shall  be  accelerated  so  that  the  options  are
immediately exercisable in full.

         6.7 Change in Control.  For  purposes of this  Agreement,  a "Change in
Control"  shall have  occurred  if at any time  during  the term of  Executive's
employment hereunder, any of the following events shall occur:

     (a)  The Company is merged,  or  consolidated.  or reorganized into or with
          another  corporation  or other legal  person,  and as a result of such
          merger,  consolidation or reorganization less than 50% of the combined
          voting power of the then-outstanding securities of such corporation or
          person immediately after such transaction are held in the aggregate by
          the holders of voting  securities of the Company  immediately prior to
          such transaction;

     (b)  The Company sells all or substantially  all of its assets or any other
          corporation or other legal person and thereafter, less than 50% of the
          combined voting power of the then-outstanding voting securities of the
          acquiring  or  consolidated  entity are held in the  aggregate  by the
          holders of voting securities of the Company  immediately prior to such
          sale;

     (c)  There is a report  filed after the date of this  Agreement on Schedule
          13 D or schedule 14 D-1 (or any successor  schedule,  form or report),
          each as promulgated  pursuant to the  Securities  Exchange Act of l934
          (the "Exchange Act")  disclosing that any person (as the term "person"
          is used in Section  13(d)(3) or Section  14(d)(2) of the exchange Act)
          has  become  the  beneficial  owner (as the term  beneficial  owner is
          defined  under  Rule  13d-3  or  any  successor   rule  or  regulation
          promulgated  under the Exchange Act)  representing  50% or more of the
          combined voting power of the then-outstanding voting securities of the
          Company;

     (d)  The Company shall file a report or proxy statement with the Securities
          and Exchange  Commission  pursuant to the Exchange Act  disclosing  in
          response to item 1 of Form 8-X  thereunder or Item 5(f) of Schedule 14
          A  thereunder  (or any  successor  schedule,  form or  report  or item
          therein)  that the change in control  of the  Company  has or may have
          occurred  or  will  or  may  occur  in  the  future  pursuant  to  any
          then-existing contract or transaction; or

     (e)  During any period of two  consecutive  years,  individuals  who at the
          beginning of any such period  constitute  the directors of the Company
          cease for any reason to constitute at least a majority  thereof unless
          the  election  to  the   nomination  for  election  by  the  Company's
          shareholders of each director of the Company first elected during such
          period was approved by a vote of at least  two-thirds of the directors
          of the Company then still in office who were  directors of the Company
          at the beginning of such period.

         6.8 Termination by Executive.  At any time, Executive may terminate his
employment by giving thirty (30) days advance written notice to the Company. The
Company shall pay Executive all Accrued Compensation,  but no other compensation
or  reimbursement  of  any  kind,   including  without   limitation,   severance
compensation,   and  thereafter  the  Company's   obligations   hereunder  shall
terminate.

         6.9  Mitigation  Except  as  otherwise  specifically  provided  herein,
Executive  shall not be required to mitigate the amount of any payment  provided
under this Agreement by seeking other employment or  self-employment,  nor shall
the amount of any payment  provided  for under this  Agreement be reduced by any
compensation  earned by Executive as a result of employment by another  employer
or  through  self-employment  or  by  retirement  benefits  after  the  date  of
Executive's termination of employment from the Company.

         6.10 Coordination If upon termination of employment,  Executive becomes
entitled to rights under other plans,  contracts or arrangements entered into by
the Company, this Agreement shall be coordinated with such other arrangements so
that  Executive's  rights under this  Agreement  are not  reduced,  and that any
payments  under  this  Agreement  offset the same  types of  payments  otherwise
provided under such other arrangements, but do not otherwise reduce any payments
or benefits under such other arrangements to which Executive becomes entitled.

                                    ARTICLE 7

                               GENERAL PROVISIONS

         7.1  Governing  law. The  validity,  interpretation,  construction  and
performance of this Agreement and the rights of the parties  thereunder shall be
interpreted and enforced under California law without reference to principles of
conflicts of laws.  The parties  expressly  agree that inasmuch as the Company's
headquarters  and principal  place of business are located in California,  it is
appropriate that California law govern this Agreement.

         7.2 Assignment; Successors Binding Agreement.

                  7.2.1  Executive  may  not  assign,  pledge  or  encumber  his
         interest in this Agreement or any part thereof.

                  7.2.2 The Company will require any successor  (whether  direct
         or indirect, by purchase, merger, consolidation or otherwise) to all or
         substantially  all of the business  and/or  assets of the  Company,  by
         operation  of law or by  agreement  in form  and  substance  reasonably
         satisfactory  to  Executive,  to  assume  and  agree  to  perform  this
         Agreement  in the same  manner and to the same  extent that the Company
         would be required to perform it if no such succession had taken place.

                  7.2.3  This  Agreement  shall  inure to the  benefit of and be
         enforceable   by   Executive's   personal  or  legal   representatives,
         executors, administrators, successors, heirs, distributee, devisees and
         legatees.  If  Executive  should  die while any  amount is at such time
         payable to his hereunder,  all such amounts,  unless otherwise provided
         herein, shall be paid in accordance with the terms of this Agreement to
         Executive's devisee,  legates or other designee or, if there be no such
         designee, to his estate.

         7.3  Certain  Reduction  of  Payments  In the event that any payment or
benefit  received or to be  received by  Executive  under this  Agreement  would
result in all or a portion  of such  payment  to be subject to the excise tax on
"golden  parachute  payments" under Section 4999 of the Internal Revenue Code of
1986, as amended (the "Code"),  then Executive's payment shall be either (a) the
full  payment or (b) such lesser  amount which would result in no portion of the
payment being subject to excise tax under Section 4999 of the Code, whichever of
the foregoing  amounts,  taking into account the applicable  Federal,  state and
local employment taxes, income taxes, and the excise tax imposed by Section 4999
of the Code,  results in the receipt by Executive on an after-tax  basis, of the
greatest amount of the payment  notwithstanding  that all or some portion of the
payment may be taxable under Section 4999 of the Code.

         7.4 Notice.  For the purposes of this Agreement,  notices and all other
communications  provided for in this Agreement  shall be in writing and shall be
deemed  to have been duly  given  when  delivered  or  mailed  by  certified  or
registered mail,  return receipt  requested,  postage prepaid,  addressed to the
respective  addresses  set forth below or to such other  address as either party
may have furnished to the other in writing in accordance  herewith,  except that
notice of change of address shall be effective only upon receipt.

         To the Company:

         Neurocrine Biosciences, Inc.
         10555 Science Center Drive
         San Diego, CA 92121
         Attn.: President & Chief Executive Officer

     To Executive:
         Ms. Margaret Valeur-Jensen
         4507 South Lane
         Del Mar, CA  92014


         7.5  Modification;  Waiver;  Entire  Agreement.  No  provisions of this
Agreement may be modified, waived or discharged unless such waiver, modification
or discharge is agreed to in writing signed by Executive and such officer as may
be  specifically  designated  by the Board of the  Company.  No waiver by either
party  hereto at any time of any  breach by the  other  party of, or  compliance
with, any condition or provision of this Agreement to be performed by such other
party shall be deemed a waiver of similar or dissimilar provisions or conditions
at the same or any prior or subsequent  time. No agreements or  representations,
oral or otherwise, express or implied, with respect to the subject matter hereof
have  been  made by  either  party  which  are not  expressly  set forth in this
Agreement.

         7.6 Validity.  The invalidity or  unenforceability  of any provision of
this  Agreement  shall not affect the  validity or  enforceability  of any other
provision of this Agreement, which shall remain in full force and effect.

         7.7  Controlling  Document.  Except to the extent  described in Section
6.l0,  in case of  conflict  between  any of the  terms  and  condition  of this
Agreement and the document  herein referred to, the terms and conditions of this
Agreement shall control.

         7.8 Executive  Acknowledgment.  Executive  acknowledges (a) that he has
consulted with or has had the opportunity to consult with independent counsel of
his own choice  concerning this Agreement,  and has been advised to do so by the
Company, and (b) that he has read and understands the Agreement,  is fully aware
of its legal effect, and has entered into it freely based on his own judgment.

         7.9 Remedies

                  7.9.1 Injunctive  Relief.  The parties agree that the services
         to be rendered by Executive  hereunder  are of a unique nature and that
         in the event of any breach or threatened breach of any of the covenants
         contained  herein,  the damage or imminent  damage to the value and the
         goodwill of the Company's  business will be  irreparable  and extremely
         difficult  to  estimate,  making  any  remedy  at  law  or  in  damages
         inadequate.  Accordingly,  the parties  agree that the Company shall be
         entitled to  injunctive  relief  against  Executive in the event of any
         breach or threatened  breach of any such  provisions  by Executive,  in
         addition  to any  other  relief  (including  damage)  available  to the
         Company under this Agreement or under law.

                  7.9.2 Exclusive.  Both parties agree that the remedy specified
         in Section  7.9.1 above is not  exclusive  of any other  remedy for the
         breach by Executive of the terms hereof.

         7.10  Counterparts.  This  Agreement  may be  executed  in one or  more
counterparts,  all of which taken  together  shall  constitute  one and the same
Agreement.

         7.11  Prevailing  Party  Expenses.  In the  event  that any  action  or
proceeding is commenced to enforce the  provisions of the  Agreement,  the court
adjudicating  such action or proceeding  shall award to the prevailing party all
costs and  expenses  thereof,  including,  but not  limited  to, all  reasonable
attorneys' fees, court costs, and all other related expenses.

Executed by the parties as of the day and year first above written.

EXECUTIVE                                    NEUROCRINE BIOSCIENCES, INC

By: /s/Bruce Campbell, Ph.D.                 By: /s/Gary A. Lyons
    Bruce Campbell, Ph.D.                    Gary A. Lyons
                                             President & Chief Executive Officer