Exhibit 10.35

               FIRST AMENDMENT TO MEMBERSHIP PURCHASE AGREEMENT &
                      COLOMBO EMPLOYMENT AGREEMENT & NOTE C
                              Dated APRIL 30, 2004

     The parties to this First  Amendment to Membership  Purchase  Agreement and
Colombo  Employment  Agreement  and Note C (the  "Agreement")  are PHC,  Inc., a
Massachusetts corporation ("PHC" or "Buyer"),  Pivotal Research Centers, L.L.C.,
an Arizona limited  liability  company  ("Pivotal"),  Louis C. Kirby  ("Kirby"),
Anthony A. Bonacci ("Bonacci") and Carol A. Colombo ("Columbo") (Kirby,  Bonacci
and Colombo may be collectively referred to herein as the "Sellers") and Michael
J. Colombo  ("MColumbo").  This  Amendment  shall amend that certain  Membership
Purchase Agreement between Buyer,  Pivotal and Sellers dated April 30, 2004 (the
"Agreement"),  the Colombo  Employment  Agreement  (as that term  defined in the
Agreement) and Note C (as that term is defined in the Agreement).

     All capitalized  terms not otherwise  defined herein shall have the meaning
ascribed  to  them  in  the  Membership  Purchase  Agreement  or the  Notes,  as
applicable.  For  purposes of this  Amendment,  "CEO" means the Chief  Executive
officer of Pivotal and the CEO of PHC divisions,  subsidiaries and/or affiliates
conducting  Clinical Research  Services.  MColumbo is the CEO under the terms of
the Colombo Employment Agreement.

     Except as specifically  amended  hereby,  all of the terms of the Agreement
and the Colombo Employment  Agreement shall remain in full force and effect. The
Agreement
is hereby amended as follows:

1.   Financial  Control Over Clinical  Research  Services.  Except to the extent
     prohibited  by all  applicable  laws,  Buyer hereby agrees that all routine
     accounting and financial  functions relating to Clinical Research Services,
     including but not limited to maintaining all books and records  relating to
     Clinical Research Services,  maintaining depository bank accounts,  payroll
     input, receipt and deposit of payment for accounts receivable,  and writing
     checks for immediate  needs  associated  with providing  Clinical  Research
     Services,  will be performed in Arizona under the authority of the CEO, and
     reported to Buyer's corporate office on a schedule  established by Buyer's.
     All accounting and financial functions for Clinical Research Services shall
     be  performed  in  accordance  with  industry  appropriate   processes  and
     procedures  shall comply with applicable Law, as approved by Bruce Shear on
     behalf  of  Buyer.  The  CEO  will  oversee  all  of the  above  referenced
     accounting and financial controls related to Clinical Research Services and
     such  oversight is hereby added to and included  within the  definition  of
     MColombo's   material  duties  under  the  Colombo  Employment   Agreement.
     Notwithstanding  the above,  Buyer shall retain the right to issue from its
     corporate office checks for payables related to Clinical Research Services.
     With respect to the Clinical Research Services payables,  Buyer's corporate
     office  will take all  reasonable  and  necessary  measures  to ensure that
     payables are paid when due. To ensure  prompt  payment of  payables,  Buyer
     hereby agrees to the  following  procedures:  (i) if the CEO  authorizes an
     expenditure  related  to  Clinical  Research  Services,  it will be paid by
     Buyer's   corporate  office  without  delay;  (ii)  payroll  for  employees
     performing  Clinical Research Services will be paid as scheduled  bi-weekly
     in the amount  specified by the CEO, (iii) Buyer will not adjust the amount


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     of or delay the  issuance  of bonus  checks to Clinical  Research  Services
     employees;  (v) cash  advances  for travel  will be approved by the CEO and
     processed by Buyer's corporate office in an expeditious  manner;  (vi) cash
     reimbursements  for  travel  will be paid  within  two weeks of  receipt by
     Buyer's  corporate  office  of an  expense  report,  provided  such  travel
     reimbursements  have been reviewed and approved by the CEO, and (vii) Louis
     Kirby, Shannon Bird, Mike Colombo,  shall each be issued a corporate credit
     card,  which they shall be responsible to use in a commercially  reasonable
     manner and only for company business, provided, however that any failure to
     use the  cards  in a  commercially  reasonable  manner  may  result  in the
     termination such privilege for the offending party. Airline travel shall be
     booked through PHC's corporate office.

2.   Full Operational Control over Clinical Research Services. Buyer agrees that
     all  operational  control  related to Clinical  Research  Services shall be
     maintained by CEO, which shall specifically include, but not be limited to,
     full  authority and control over:  (i) all  employees  performing  Clinical
     Research Services,  (ii) the employee  compensation  structure put in place
     annually  by the  CEO  for  Clinical  Research  Services  employees,  which
     compensation  structure  shall be  within  industry  market  ranges  unless
     otherwise approved by Buyer,  provided Buyer shall have the right to review
     and  approve  compensation  structure  for any  executive  level  employees
     proposed to be hired by the CEO related to Clinical Research Services,  and
     (iii) hiring and firing personnel  performing  Clinical Research  Services,
     with all such activities  being added to and included within the definition
     of MColombo's material duties under the Colombo Employment Contract.

3.   Financial  Reporting.  Buyer shall  provide to Sellers,  through the CEO, a
     monthly financial  statement relating to all Clinical Research Services and
     Buyer shall provide Sellers,  upon receipt of written request,  with access
     to the  information  used in or  underlying  such  financial  reports (this
     request,  if  made,  will be made to  PHC's  CEO,  who  will  fulfill  such
     request).

4.   Note C. With respect to Note C, the definition of Adjusted EBITDA is hereby
     modified to exclude any of Buyer's  intra-company  or related company debt,
     including but not limited to debt  attributed to PPR.  Adjusted EBITDA also
     shall  not  include  any  corporate  overhead  charges  on the  Non-Pivotal
     Business  in excess of $50,000 per annum,  and no direct  third party costs
     incurred  and paid by  Buyer's  corporate  office on behalf of  Non-Pivotal
     Business  shall  exceed the market  rate at which  such  services  could be
     obtained from unrelated third parties. If the Non-Pivotal Business pays any
     inter-company or related company debt, or any corporate overhead charges in
     excess of $50,000 per annum, or incurs any direct costs at prices in excess
     of prevailing  market rates, then all such amounts shall be added back into
     the Adjusted EBITDA.

5.   Insurance.  The  undersigned  parties agree that the Landmark  Professional
     Liability  Insurance Policy (the "Landmark  Policy") will be prorated as of
     Closing with Sellers  responsible  only for costs  related to the period of
     coverage  from  2/15/04 to  2/28/04,  and (ii) no  portion of the  Landmark
     Policy,  including  retroactive  coverage,  will be  charged  to Sellers or
     offset against amounts owed to Sellers.

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IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be signed
on the date and year first above written.


                                         PHC, INC., A MASSACHUSETTS
                                         CORPORATION




                                         By:  /s/ Bruce A. Shear, President




                                         PIVOTAL RESEARCH CENTERS, L.L.C.


                                         /s/ Louis C. Kirby


                                         MICHAEL J COLOMBO



                                         /s/ Michael J. Colombo





                                         SELLERS:



                                         /s/ Louis C. Kirby
                                             5633 North Royal Circle
                                             Paradise Valley, AZ  85253


                                         /s/ Carol A. Colombo
                                             2525 E. Camelback Road, Suite 840
                                             Phoenix, AZ  85016




                                         /s/ Anthony A. Bonacci
                                             2525 E. Camelback Road, Suite 840
                                             Phoenix, AZ  85016



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