Exhibit 21.1 Name of Subsidiary Doing Business As (Name) State of Incorporation PHC, Inc. Pioneer Behavioral Health Massachusetts PDS2 Massachusetts Pioneer Recovery Systems Massachusetts PHC of Utah, Inc. Highland Ridge Hospital Massachusetts Wellplace Massachusetts PHC of Virginia, Inc. Mount Regis Center Massachusetts Changes PHC of Michigan, Inc. Harbor Oaks Hospital Massachusetts Pioneer Healthcare of Michigan Massachusetts Wellplace Call Center Massachusetts Detroit Behavioral Institute Massachusetts PHC of Nevada, Inc. Harmony Healthcare Massachusetts Harmony Behavioral Healthcare Nevada Northpoint-Pioneer, Inc. Pioneer Counseling Center Massachusetts Pioneer Healthcare of Michigan Massachusetts Pioneer Pharmaceutical Research Massachusetts PHC of Kansas, Inc. Total Concept, EAP Massachusetts Pioneer Counseling of Virginia, Inc. Counseling Associates of Virginia Massachusetts BSC-NY, Inc. Behavioral Stress Center New York Professional Health Associates, Inc. New York Behavioral Health Online BehavioralHealthOnLine.com Massachusetts Wellplace Detroit Behavioral Institute, Inc. Massachusetts Wellplace, Inc. Massachusetts Pivotal Research Centers, Inc. Pivotal Research Centers Delaware Pivotal Research Centers, LLC