Exhibit 8.1
                              Lathrop & Gage L.C.
                              2345 Grand Boulevard
                          Kansas City, Missouri 64108

Russell D. Jones
(816) 460-5725
Email: rjones@lathropgage.com

                                __________, 1999
                                    (Draft)
Lab Holdings, Inc.
5000 West 95th Street
Suite 260, Box 7568
Shawnee Mission, Kansas  66207

LabOne, Inc.
10101 Renner Boulevard
Lenexa, Kansas  66219

   Re: Merger of LabOne, Inc. into Lab Holdings, Inc.

Dear Sirs:

   We represent Lab Holdings, Inc., a Missouri corporation ("Lab Holdings"),  in
connection  with  the  merger  (the  "Merger")  of  LabOne,   Inc.,  a  Delaware
corporation ("LabOne"), into Lab Holdings pursuant to that certain Agreement and
Plan of Merger, as amended and restated,  dated as of March 7, 1999 (the "Merger
Agreement").  The Merger is described in a joint Proxy  Statement/Prospectus  of
Lab Holdings and LabOne (as amended to date, the "Prospectus")  that is included
in a Registration  Statement on Form S-4 (Registration No. 333-_____) filed with
the Securities and Exchange Commission with respect to the Merger (as amended to
date, the "Registration Statement").

   Section 6.1(g) of the Merger  Agreement  provides that the obligation of each
of you to effect  the  Merger  shall be  subject  to your  receipt of an opinion
letter of counsel to the effect that the Merger will have certain federal income
tax consequences. This opinion letter is being delivered to each of you pursuant
to such Section 6.1(g).

   We have  examined such  documents  and records and made such  inquiries as we
consider  relevant  and  necessary  for  purposes  of this  opinion  letter.  In
particular  we have  reviewed  the Merger  Agreement,  the  Prospectus,  and the
Registration  Statement.  Also in particular we have reviewed upon a Certificate
of Fact that has been  provided to us by you.  Based upon such  examination  and
inquiry,  and further based on the assumptions and subject to the qualifications
set forth below, we are of the opinion that the federal income tax  consequences
of the Merger include the following.




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Page 2

Holdings

   With respect to Holdings the Merger will qualify as a tax-free liquidation of
LabOne  under  Section 332 of the Internal  Revenue  Code of 1986 (the  "Code").
Accordingly,  and taking into account other  applicable  rules,  no gain or loss
will be  recognized  by  Holdings  upon  the  receipt  by it of all of  LabOne's
property and the cancellation of its LabOne stock pursuant to the Merger or as a
result of the stock split that precedes the Merger. However, and notwithstanding
the preceding  sentence,  Holdings will at the time of the Merger  recognize any
gain or loss that is realized by it upon its receipt of property  from LabOne in
satisfaction  of any debt that is then  owed to it by  LabOne.  Also,  and again
notwithstanding  the first sentence of this paragraph,  Holdings may at the time
of the  Merger  recognize  income  from the  discharge  of  indebtedness  if any
indebtedness is then owed by it to LabOne.

   Holdings'  initial  tax basis in each of the  properties  received by it from
LabOne  pursuant to the Merger will be the same as  LabOne's  tax basis  therein
immediately  before  the  Merger.  Holdings'  holding  period  for the  property
received  by it from LabOne  pursuant to the Merger will  include the period for
which the property was held by LabOne.

LabOne

   With respect to LabOne the Merger will qualify as a tax-free  liquidation  of
LabOne under  Section 332.  Accordingly,  no gain or loss will be  recognized by
LabOne upon the  distribution by it of all of its property to Holdings  pursuant
to the Merger.

Holdings Stockholders

   In general the Merger will have no effect on Holdings stockholders.  However,
and notwithstanding the preceding  sentence,  Holdings  stockholders who receive
cash in lieu of  fractional  shares  in  connection



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with  the  stock split that  precedes the Merger will  be treated as if they had
received the  fractional  shares and such shares were then redeemed by Holdings.
As discussed in more detail  below,  the specific tax  consequences  to Holdings
stockholders  of a deemed  redemption  of  Holdings  stock  will  depend  on the
stockholders'  individual  circumstances.  Therefore, we express no opinion with
respect to the specific tax  consequences  to any  Holdings  stockholder  of the
receipt of cash in lieu of a  fractional  share of  Holdings  stock in the stock
split that  precedes the Merger.  We note,  however,  that the Internal  Revenue
Service (the "IRS") has ruled that a stockholder  who receives cash in lieu of a
fractional  share  in  connection  with a stock  dividend  or stock  split  will
generally  recognize  gain or loss on the deemed  redemption of such  fractional
share in an amount equal to the  difference  between the amount of cash received
and the stockholder's tax basis in such fractional share, provided that the cash
is distributed  solely for the purpose of saving the corporation the expense and
inconvenience  of  issuing  and  transferring   fractional  shares  and  is  not
separately bargained-for consideration.

   Similarly,  and also  notwithstanding  the first  sentence  of the  preceding
paragraph,  Holdings stockholders who receive cash as a result of their exercise
of statutory  dissenters' rights will be treated as if their Holdings stock were
redeemed  by  Holdings.  This  deemed  redemption  will be  treated as a sale or
exchange of such a stockholder's  Holdings stock,  and thus will trigger capital
gain or  loss,  if it is  considered  to be  "not  essentially  equivalent  to a
dividend"  under Section  302(b)(1) or if it is considered to be  "substantially
disproportionate"  with respect to the stockholder under Section 302(b)(2) or if
it results in a complete  termination of the stockholder's  interest in Holdings
under  Section  302(b)(3);  otherwise  the cash  received  will be  treated as a
dividend.  In determining  whether the deemed redemption is treated as a sale or
exchange the  constructive  ownership rules of Section 318,  pursuant to which a
stockholder  is treated as owning stock that is actually  owned by certain other
related parties, are generally applicable.

   A  deemed  redemption  of  Holdings  stock  held  by  a  dissenting  Holdings
stockholder will be considered to be "not essentially  equivalent to a dividend"
under Section 302(b)(1) if the redemption results in a



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Page 4

"meaningful  reduction"   in   the  stockholder's   proportionate   interest  in
Holdings.  U.S. v. Davis, 397 U.S. 301, 313, reh'g denied, 397 U.S. 1071 (1970).
The  existence  and extent of any decrease in voting  control  appears to be the
most  significant  factor to be taken into account in applying this  "meaningful
reduction"  test,  although  the  existence  and extent of decreases in economic
ownership are also relevant considerations.

   A  deemed  redemption  of  Holdings  stock  held  by  a  dissenting  Holdings
stockholder  will be  considered  to be  "substantially  disproportionate"  with
respect to the stockholder under Section  302(b)(2) if the stockholder  actually
and  constructively  owns  less  than 50  percent  of the  voting  power  of the
outstanding  Holdings stock after the deemed redemption and if the percentage of
Holdings stock actually and  constructively  owned by such stockholder after the
deemed  redemption is less than 80 percent of the  percentage of Holdings  stock
actually and  constructively  owned by such stockholder  immediately  before the
deemed redemption.

   As indicated in the foregoing discussion,  the specific tax consequences of a
deemed  redemption of the Holding stock of a Holdings  stockholder who exercises
statutory  dissenters'  rights  will  depend  on such  stockholder's  individual
circumstances. Therefore, we express no opinion with respect to the specific tax
consequences  of such deemed  redemption  treatment to any  particular  Holdings
stockholder.

LabOne Stockholders (Other Than Holdings)

   With respect to LabOne  stockholders  (other than  Holdings)  the Merger will
qualify as a tax-free  reorganization under Section 368(a) and both Holdings and
LabOne will be parties to such reorganization under Section 368(b). Accordingly,
the  principal  tax  consequences  of the  Merger  to such  stockholders  are as
follows.

   No gain or loss will be  recognized by LabOne  stockholders  who receive only
Holdings stock in exchange for their LabOne stock pursuant to the Merger.



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   LabOne  stockholders who receive only cash in exchange for their LabOne stock
pursuant to the Merger will likely be treated as if they had  received  Holdings
stock  in the  Merger  and such  stock  was  redeemed  by  Holdings  immediately
thereafter, although the law in this regard is unclear and such stockholders may
be  treated  as if they had  sold  their  LabOne  stock  to  Holdings.  A deemed
redemption  of LabOne  stock will be treated,  under the rules  discussed  above
regarding deemed redemptions of Holdings stock,  either as a sale or exchange of
LabOne  stock (with the  recognition  of capital gain or loss) or as a dividend,
depending on the stockholder's individual circumstances. A deemed sale of LabOne
stock to Lab  Holdings  would  cause the  recognition  of capital  gain or loss.
Because of the  uncertainty in the law, and because of the LabOne  stockholders'
varying  circumstances,  we express no opinion  with respect to the specific tax
consequences  of the  Merger to LabOne  stockholders  who  receive  only cash in
exchange for their LabOne stock pursuant thereto.

   LabOne stockholders who receive some Holdings stock and some cash in exchange
for their LabOne stock pursuant to the Merger will recognize gain, but not loss,
on such exchange.  The amount of the gain recognized by such a stockholder  will
be equal to the lesser of: one, the total gain realized by such  stockholder  on
the  exchange  (i.e.,  the value of the Merger  consideration  received  by such
stockholder, including both cash and Holdings stock, less such stockholder's tax
basis in the LabOne stock that is given up in the exchange);  or two, the amount
of cash  received.  The gain that is  realized  by a LabOne  stockholder  may be
capital  gain or ordinary  income,  depending  on the  stockholder's  individual
circumstances   (determined  in  accordance  with  the  rules  regarding  deemed
redemptions  that are  discussed  above,  applied as if the  LabOne  stockholder
exchanged  all of his LabOne stock for Holdings  stock and Holdings  immediately
redeemed  a portion  of such  Holdings  stock for  cash).  Because of the LabOne
stockholders' varying  circumstances,  we express no opinion with respect to the
character of the gain,  if any,  recognized by LabOne  stockholders  who receive
some Holdings stock and some cash in exchange for their LabOne stock pursuant to
the Merger.

   The aggregate tax basis of the shares of Holdings  stock received by a LabOne
stockholder pursuant to the Merger will equal the aggregate



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tax  basis  of  such  stockholder's  shares of LabOne  stock  exchanged  in  the
Merger,  increased by the amount of any gain recognized by such  stockholder and
decreased by the amount of any cash  received by such  stockholder.  The holding
period for shares of Holdings stock received by a LabOne stockholder pursuant to
the Merger  will  include  the  holding  period  for the shares of LabOne  stock
exchanged in the Merger.

   The  foregoing  opinions  are based on the  Code,  its  legislative  history,
Treasury  Regulations,   judicial  authority,  and  administrative  rulings  and
practice,  all as currently  existing and in effect.  This opinion letter is not
binding  on the IRS or upon the  courts,  and if the IRS  challenges  any of the
opinions  that are  expressed  herein  substantial  expense  may at a minimum be
incurred in dealing therewith. Legislative,  judicial, or administrative changes
or  interpretations  may be forthcoming  that could alter or modify the opinions
expressed by us herein.  Any such changes may be  retroactive  and could affect,
possibly adversely, the tax consequences of the Merger.

   In  rendering  the  foregoing  opinions we have  assumed the  accuracy of all
statements  of fact  contained  in the Merger  Agreement,  the  Prospectus,  the
Registration  Statement,  and other  documents  examined  by us or made to us by
officers or other  representatives of Lab Holdings and LabOne in response to our
inquiries.  We have also assumed the due authorization,  execution and delivery,
and  binding  effect  of all  contracts  examined  by us by  and on all  parties
thereto.  We have  further  assumed the  genuineness  of all  signatures  on all
contracts and other documents  examined by us, the authenticity of all documents
submitted to us as originals,  and the  conformity to original  documents of all
documents submitted to us as copies.

   We express no opinion as to the federal income tax consequences of the Merger
if any of the  assumptions  that we are  relying  upon in issuing  this  opinion
letter are incorrect.  We also express no opinion as to the tax  consequences of
the Merger under any state, local, or foreign tax law.

   The opinions set forth in this letter are effective as of the date hereof. We
express no opinions other than as herein  expressly set forth,  and no expansion
of our opinions may be made by implication or otherwise.  We do not undertake to
advise you of any  matter  within the scope of this  letter  which  comes to our
attention after the delivery of this letter and disclaim any  responsibility  to
advise you of future changes in law or fact which may affect the above opinions.



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Page 7

   This opinion letter may not be filed with any governmental  agency or be used
for any other  purpose  without  our prior  written  consent,  except  that this
opinion letter may be filed as an exhibit to the Registration  Statement.  Also,
we  consent  to the  reference  that  is  made to  this  opinion  letter  in the
Prospectus  under the caption "The Proposed  Merger--Federal Income Tax
Consequences."

                                                Very truly yours,

                                                LATHROP & GAGE L.C.


                                                By:
                                                   ----------------------------
                                                   Russell D. Jones