News Release

Contacts:

Integra LifeSciences Holdings Corporation

John B. Henneman, III                   Maria Platsis
Executive Vice President                Senior Director of Corporate Development
Chief Administrative Officer            and Investor Relations
(609) 936-2481                          (609) 936-2333
jhenneman@Integra-LS.com                mplatsis@Integra-LS.com


               Integra LifeSciences Closes its Acquisition of the
                 Radionics Division of Tyco Healthcare Group LP

Plainsboro, New Jersey / March 5, 2006 -- Integra LifeSciences Holdings
Corporation (NASDAQ: IART) announced today that it has acquired the assets of
the Radionics Division of Tyco Healthcare Group LP for $80 million in cash,
subject to certain adjustments.

Radionics, based in Burlington, Massachusetts, is a leader in the design,
manufacture and sale of advanced minimally-invasive medical instruments in the
fields of neurosurgery and radiation therapy. Radionics' products include the
CUSA EXcel(TM) ultrasonic surgical aspiration system, the CRW(TM) stereotactic
system, the XKnife(TM) stereotactic radiosurgery system, and the OmniSight(TM)
EXcel image guided surgery system.

As part of the transaction, Integra has assumed the lease on the Radionics
facility in Burlington, Massachusetts, which employs approximately 135
employees, and has entered into transitional supply and distribution agreements
with Tyco Healthcare Group LP for products currently manufactured at Tyco
facilities not included in the transaction.

The transaction offers a number of strategic benefits to Integra LifeSciences:

    o    Increases its global neurosurgery product offering with the addition of
         an ultrasonic surgical aspirator product line, including handpiece,
         tip, and energy delivery designs utilizing magnetostrictive technology.

    o    Positions the company to offer new stereotactic surgery products by
         combining its existing Mayfield(R) and Budde(TM) head-holding and
         retraction products with Radionics' CRW stereotactic head frame.

    o    Secures entry into the radiosurgery/radiotherapy and image-guided
         surgery device business.

    o    Adds to its manufacturing and R&D expertise in electronics,
         ultrasonics, and software.

    o    Enhances the efficiencies of its global infrastructure and distribution
         network through economies of scale and cost synergies.

"This acquisition represents an ideal strategic fit for Integra LifeSciences. It
expands our revenue base and enhances our cash flow and profitability," said
Stuart M. Essig, Integra's President and Chief Executive Officer. "It also
increases our international business significantly as approximately 50 percent
of Radionics' business is outside of the United States."




The CUSA EXcel(TM) ultrasonic surgical aspiration system is a well-recognized
medical device used in the selective removal of soft tissue in surgical
procedures. The Radionics products are primarily utilized by neurosurgeons in
the diagnosis and treatment of cancer and in the treatment of movement
disorders. Neurosurgeons use the CRW(TM) stereotactic system, which allows for
the positioning of fine instruments in the brain with submillimeter accuracy,
for minimally invasive brain biopsies, stereotactic craniotomies, and the
placement of radiofrequency probes or stimulating electrodes for the treatment
of neurological disorders. The XKnife(TM) system is used in the non-invasive
treatment of intracranial brain lesions, and the OmniSight(TM) EXcel system
provides neurosurgeons and orthopedic surgeons with enhanced three-dimensional
visualization of critical anatomy and the ability to perform less invasive
surgical procedures.

"The acquisition of Radionics strengthens Integra's product offering in
neurosurgery," said Mr. Essig. "The Radionics products provide an exceptional
complement to the portfolio of products already offered by Integra LifeSciences.
We have great respect for the Radionics team members who have brought so many
outstanding technologies to the neurosurgery device market," Mr. Essig added.

Tyco Healthcare Group LP sells the Radionics products in over 75 countries,
using a network of independent distributors in the United States and both
independent distributors and Tyco Healthcare Group LP affiliates
internationally.

Integra expects to provide detailed guidance regarding the financial aspects of
the transaction, including the impact of purchase accounting, and its expected
impact on Integra's future financial results on its fourth quarter earnings
conference call scheduled for March 6, 2006.

Integra LifeSciences Holdings Corporation is a diversified medical technology
company that develops, manufactures, and markets medical devices for use in a
variety of applications. The primary applications for our products are
neurosurgery, reconstructive surgery and general surgery. Integra is a leader in
applying the principles of biotechnology to medical devices that improve
patients' quality of life. Our corporate headquarters are in Plainsboro, New
Jersey, and we have manufacturing and research facilities located throughout the
world. We have approximately 1,400 employees. Please visit our website at
(http://www.Integra-LS.com).

This news release contains forward-looking statements within the meaning of the
Private Securities Litigation Reform Act of 1995. Forward-looking statements
include, but are not limited to, statements concerning expectations for this
newly acquired business and the expected impact of this acquisition on Integra's
future financial results. Such forward-looking statements involve risks and
uncertainties that could cause actual results to differ materially from
predicted or expected results. Among other things, Integra's ability to
successfully integrate the Radionics product lines into its operations could
affect the impact of this acquisition on Integra's future financial results. In
addition, the economic, competitive, governmental, technological and other
factors identified under the heading "Factors That May Affect Our Future
Performance" included in the Business section of Integra's Annual Report on Form
10-K for the year ended December 31, 2004 and information contained in
subsequent filings with the Securities and Exchange Commission could affect
actual results.

Source: Integra LifeSciences Holdings Corporation