3


                                AMENDMENT 2006-1
                                     TO THE
                   STUART M. ESSIG RESTRICTED UNITS AGREEMENT
                         DATED AS OF DECEMBER 22, 2000


         AMENDMENT, dated as of October 30, 2006, between Integra LifeSciences
Holdings Corporation, a Delaware Corporation (the "Company") and Stuart M. Essig
(the "Executive").

                                    RECITALS

         WHEREAS, pursuant to a Restricted Units Agreement, dated as of December
22, 2000, (the "RSU Agreement") the Company granted to Executive an aggregate of
1,250,000 restricted units (the "Units") that represented an equal number of
shares of restricted common stock of the Company, par value $0.01 per share,
("Common Stock") under the Integra LifeSciences Holdings Corporation 2000 Equity
Incentive Plan;

         WHEREAS, the RSU Agreement provided that if Executive was employed by
the Company on December 31, 2005, the Units awarded to Executive would be paid
to him on January 1, 2006;

         WHEREAS, the RSU Agreement also provided that during the 20-year period
ending June 30, 2005, Executive had the right to defer delivery of the shares of
Common Stock of the Company corresponding to the Units (the "Unit Shares") on as
many occasions as Executive determines by providing written notice to the
Company no less than six months prior to the next scheduled delivery date for
the Unit Shares (which was extended to twelve months pursuant to Executive's
Second Amended and Restated Employment Agreement, dated as of July 27, 2004);

         WHEREAS, on December 21, 2004, Executive elected to defer receipt of
500,000 of the Unit Shares to March 4, 2008;

         WHEREAS, on January 3, 2006, the 750,000 Unit Shares that were not
deferred pursuant to Executive's prior deferral election were distributed to
him;

         WHEREAS, after the grant of the Units to Executive, section 409A was
added to the Internal Revenue Code of 1986, as amended (the `Code");

         WHEREAS, based on the available guidance issued under section 409A of
the Code, it was determined that the provisions of section 409A of the Code
apply to the Unit Shares that have not previously been paid;

         WHEREAS, the Company and Executive mutually desire to amend the RSU
Agreement to comply with the requirements of section 409A of the Code; and

         WHEREAS, Section 11 of the RSU Agreement provides that the RSU
Agreement may be amended if the amendment is agreed to in writing between
Executive and the Company.



         NOW, THEREFORE, the Company and Executive hereby agree that the RSU
Agreement shall be amended as follows:

         1. Effective as of January 1, 2005, Section 4(a) of the RSU Agreement
is hereby amended in its entirety to read as follows:

                  "(a) The shares of Common Stock underlying the Units (the
                  "Unit Shares") shall be paid out to Executive as follows, if
                  Executive is still employed by the Company on December 31,
                  2005; (i) 750,000 Unit Shares on January 3, 2006, and (ii)
                  500,000 Unit Shares on March 4, 2008, or as soon as
                  administratively practicable thereafter; provided, however,
                  that Executive may subsequently defer the receipt of the Unit
                  Shares covered by clause (ii) to a later date if the election
                  to defer meets the following requirements: (x) the election to
                  defer is made at least 12 months prior to the date the Unit
                  Shares are scheduled to be delivered, (y) the new delivery
                  date is no sooner than 5 years from the date the Unit Shares
                  were scheduled to be delivered, and (z) the new election is
                  irrevocable, but shall not become effective for 12 months
                  after the date the election is made. Notwithstanding the
                  immediately preceding sentence, if the election to defer is
                  made by December 31, 2007, the requirements of clauses (x),
                  (y) and (z) shall not be applicable and Executive may choose
                  any delivery date after December 31, 2007. If the election to
                  defer delivery is made after December 31, 2007, the delivery
                  date can be delayed as many times as Executive desires;
                  provided that the latest an election can be made is June 30,
                  2020 and the latest the delivery date can be paid is June 30,
                  2025. Notwithstanding the foregoing, if a Change in Control
                  (as defined in the Employment Agreement) occurs prior to the
                  delivery date designated by Executive, the Unit Shares shall
                  be delivered to Executive on the date of the Change in
                  Control; provided, however, that such delivery shall only
                  occur if the Change in Control meets the requirements of
                  section 409A(a)(2)(v) of the Internal Revenue Code of 1986, as
                  amended (the "Code"), and its corresponding regulations."

         2. Effective as of January 1, 2005, a new Section 20 is hereby added to
the end of the RSU Agreement to read as follows:

                  "20. SECTION 409A OF THE CODE. Notwithstanding anything in
                  this Agreement to the contrary, this Agreement is intended to
                  be operated in compliance with the requirements of section
                  409A of the Code and its corresponding regulations and related
                  guidance. As a result, the Company shall not make any payments
                  under this Agreement earlier than the earliest date permitted
                  by section 409A of the Code, or later than the latest date
                  permitted by section 409A of the Code, if, as determined in
                  the reasonable judgment of the Company, payment on the
                  originally scheduled date would cause Executive to incur
                  adverse tax consequences under section 409A of the Code.
                  Further, the Company may make any amendments to this Agreement
                  as it deems necessary and appropriate for the Agreement to

                                       2


                  comply with the requirements of section 409A of the Code, and
                  the consent of Executive is not required for such amendment of
                  the Agreement."

         3. In all respects not modified by this Amendment 2006-1, the RSU
Agreement is hereby ratified and confirmed.

         IN WITNESS WHEREOF, the Company and Executive agree to the terms of the
foregoing Amendment 2006-1, effective as of January 1, 2005.


         INTEGRA LIFESCIENCES HOLDINGS
         CORPORATION

         By:/s/ Richard E. Caruso                          /s/ Stuart M. Essig
            -----------------------                        -------------------
            Name: Richard E. Caruso                        Executive
            Title: Chairman

            10/30/06                                       10/30/06
            -----------------------                        ---------------------
            Date                                           Date

                                       3