Certification of Principal Executive Officer
            Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

I, Stuart M. Essig, President and Chief Executive Officer of Integra
LifeSciences Holdings Corporation (the "Company"), hereby certify that, to my
knowledge:

1.   The Quarterly Report on Form 10-Q of the Company for the quarter ended
     September 30, 2006 (the "Report") fully complies with the requirement of
     Section 13(a) or Section 15(d), as applicable, of the Securities Exchange
     Act of 1934, as amended; and

2.   The information contained in the Report fairly presents, in all material
     respects, the financial condition and results of operations of the Company.

Date: November 9, 2006                     /s/ Stuart M. Essig
                                           -------------------
                                           Stuart M. Essig
                                           President and Chief Executive Officer