FORM 12b-25(b)
                        NOTIFICATION OF LATE FILING

                               (Check One):

[ ] Form 10-KSB   [ ] Form 20-F  [ ] Form 11-K [x] Form 10-QSB
[ ] Form N-SAR

      For Period Ended: April 30, 2000

      [ ]   Transition Report on Form 10-K
      [ ]   Transition Report on Form 20-F
      [ ]   Transition Report on Form 11-K
      [ ]   Transition Report on Form 10-Q
      [ ]   Transition Report on Form N-SAR
            For the Transition Period Ended: . . . . . . . . . . .
 . . . . .
__________________________________________________________________

      Read Attached Instruction Sheet Before Preparing Form.
Please Print or Type.

     Nothing in this form shall be construed to imply that the
Commission has verified any information contained herein.
__________________________________________________________________

     If the notification relates to a portion of the filing
checked above, identify the Item(s) to which the notification
relates:  . . . . . . . . . . .
 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
 . . . . . .
__________________________________________________________________

PART I - Registrant Information
__________________________________________________________________

     Full Name of Registrant

     Former Name if Applicable

    MedPlus, Inc.

     Address of Principal Executive Office (Street and Number)

    8805 Governor's Hill Drive, Ste. 100

     City, State and Zip Code

   Cincinnati, Ohio  45249




_____________________________________________________________

PART II - Rules 12b-25 (b) and (c)
_____________________________________________________________

If the subject report could not be filed without unreasonable
effort or expense and the registrant seeks relief pursuant to Rule
12b-25(b) [paragraph 23,047], the following should be completed.
(Check box if appropriate)

(a)   The reasons described in reasonable detail in Part III of
this form could not be eliminated without unreasonable effort or
expense;

(b)   The subject annual report, semi-annual report, transition
report on Form 10-K, Form 20-F, 11-K or Form N-SAR, or portion
thereof will be filed on or before the fifteenth calendar day
following the prescribed due date; or the subject quarterly report
or transition report on Form 10-Q, or portion thereof will be
filed on or before the fifth calendar day following the prescribed
due date; and [Amended in Release No. 34-26589 (paragraph 72,435),
effective April 12, 1989, 54 F.R. 10306.]

(c)  The accountant's statement or other exhibit required by Rule
12b-25(c) has been attached if applicable.

__________________________________________________________________

PART III - Narrative
__________________________________________________________________

State below in reasonable detail the reasons why Form 10-K, 20-F,
11-K, 10-Q, N-SAR or the transition report or portion thereof
could not be filed within the prescribed period. [Amended in
Release No. 34-26589 (paragraph 72,435), effective April 12, 1989,
54 F.R. 10306.]

The quarterly report on Form 10-QSB for MedPlus, Inc. as of April
30, 2000, could not be filed within the prescribed time period due
to unanticipated delays in the completion of certain information
in Part I of the Form 10-QSB.
__________________________________________________________________

PART IV - Other Information
__________________________________________________________________

(1)  Name and telephone number of person to contact in regard to
this notification:

Marla Kouche                   (513)          583-0500
   (Name)                  (Area Code)  (Telephone Number)

(2)  Have all other periodic reports required under Section 13 or
15(d) of the Securities Exchange Act of 1934 or section 30 of the
Investment Company Act of 1940 during the preceding 12 months or
for such shorter period that the registrant was required to file
such report(s) been filed?  If the answer is no, identify
report(s).

           [X] Yes   [ ] No

(3)  Is it anticipated that any significant change in results of
operations from the corresponding period for the last fiscal year
will be reflected by the earnings statements to be included in the
subject report or portion thereof?

                                                        [ ] Yes
[X] No

If so: attach an explanation of the anticipated change, both
narratively and quantitatively, and, if appropriate, state the
reasons why a reasonable estimate of the results cannot be made.

                          MedPlus, Inc.
         (Name of Registrant as specified in charter)

has caused this notification to be signed on its behalf by the
undersigned thereunto duly authorized.


Date: June 14, 2000               By: /s/Daniel A. Silber
                                      Daniel A. Silber
                                  Chief Financial Officer

INSTRUCTION:  This form may be signed by an executive officer of
the registrant or by any other duly authorized representative.
The name and title of the person signing the form shall be typed
or printed beneath the signature.  If the statement is signed on
behalf of the registrant by an authorized representative (other
than an executive officer), evidence of the representative's
authority to sign on behalf of the registrant shall be filed with
the form, accountant's statement or other exhibit.