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                              EXIBIT 99.1

                              [SPECTRX LETTERHEAD]
SpectRx, Inc.
October 4, 2002
Contacts
Bill Wells - Media
Thomas H. Muller, Jr. - Financial
770-242-8723

    SpectRx, Inc. May Seek Listing on NASDAQ SmallCap Market

     NORCROSS,  GA  (October 4, 2002) -- SpectRx,  Inc.  (NASDAQ:
SPRX)  today  announced that it may seek listing  on  the  NASDAQ
SmallCap Market.   The Company has received a determination  from
NASDAQ  that  it  does  not meet either the  NASDAQ  current  net
tangible  assets  requirement  or the  new  higher  stockholders'
equity  requirement for continued listing on the National  Market
tha.   SpectRx has requested a hearing to present reasons why  it
should  retain  its  National Market  Listing.   The  hearing  is
expected  to take place within 45 days and SpectRx will  continue
to  be  listed on the National Market during that time.   SpectRx
could also qualify for continued listing under alternative market
capitalization   rules,  if  its  market  capitalization   rises.
Although  there  are  no  assurances  that  the  appeal  will  be
successful or that a transfer application to the NASDAQ SmallCap
Market,  if  necessary, would be approved, the  Company  believes
that  it  meets  the  applicable SmallCap  Market  standards  for
inclusion.

     "We  believe we have the plans in place that will enable  us
to   take   steps   to  meet  NASDAQ  National   Market   listing
requirements," said Mark A. Samuels, SpectRx, Inc.  Chairman  and
CEO.   "We  have made significant progress toward those plans  --
laid  out  during  our second quarter conference  call  --  which
included  separately  funding  our non-invasive  cervical  cancer
development  program,  launching  our  initial  insulin  delivery
products,  and  moving our continuous glucose monitoring  program
forward.  If successful, these, and other activities, should help
us  raise our net tangible assets and stockholders' equity  above
the   minimum   requirement   and  perhaps   raise   our   market
capitalization as well."

     SpectRx must meet one of two maintenance standards to retain
its  National Market listing.  Standard 1 currently  requires  at
least  $4.0  million of net tangible assets but  will  change  to
$10.0 million of stockholders' equity effective November 1, 2002.
Maintenance  Standard  2  requires the  market  value  of  listed
securities to be $50 million.  There can be no assurance that the
Company  will  be able to successfully accomplish its  plans,  or
that,  if it does, that there would be any increase in the market
value of its listed securities.

About SpectRx

     SpectRx,  Inc.  is  a medical technology  company  providing
innovative detection, monitoring and treatment solutions for  the
diabetes   and   non-invasive  diagnostics  healthcare   markets.
SpectRx  is developing and will market the SimpleChoice  line  of
innovative  insulin delivery products for people  with  diabetes.
These  FDA-cleared products complement SpectRx's consumer  device
for  continuous glucose monitoring under development with  Abbott



Laboratories.   SpectRx  is also creating opportunities  for  its
leading-edge  biophotonic  detection and  monitoring  technology,
which  uses  light  and  spectral  energies  to  create  painless
alternatives  to  blood-based and tissue-based procedures.   Non-
invasive  products include a developmental non-invasive  cervical
cancer detection device.  SpectRx also markets the BiliChek  Non-
invasive   Bilirubin   Analyzer,  a  biophotonic,   non-invasive,
painless  monitor  for  infant jaundice.  For  more  information,
visit SpectRx's web site at www.spectrx.com.

     SpectRx  and BiliChek are trademarks owned by SpectRx,  Inc.
SimpleChoice,   a   SpectRx  Company,   owns   all   SimpleChoice
trademarks.

     "Safe   Harbor"  Statement  under  the  Private   Securities
Litigation  Reform  Act of 1995:  A number  of  the  matters  and
subject  areas  discussed  in this press  release  that  are  not
historical   or   current  facts  deal  with   potential   future
circumstances and developments.  The discussion of  such  matters
and  subject  areas  is  qualified  by  the  inherent  risks  and
uncertainties surrounding future expectations generally and  also
may  materially  differ from SpectRx's actual  future  experience
involving  any  of  or more of such matters  and  subject  areas.
SpectRx  has  attempted to identify, in context, certain  of  the
factors  that  it  currently believes  may  cause  actual  future
experience   and   results  to  differ  from  SpectRx's   current
expectations regarding the relevant matter or subject area.  Such
risks  and uncertainties include: the early stage of products  in
development,  its  dependence on collaborative arrangements,  the
uncertainty of market acceptance of its products, the uncertainty
of  development  or effectiveness of distribution  channels,  the
intense   competition  in  the  medical  device   industry,   the
uncertainty  of  capital to develop products, the uncertainty  of
regulatory  approval of its products, its dependence on  licensed
intellectual  property,  as well as those  that  are  more  fully
described  from  time  to  time in SpectRx's  reports  under  the
heading  "Risk  Factors" filed with the SEC, including  SpectRx's
Annual Report on Form 10-K for the fiscal year ended December 31,
2001 and subsequent quarterly reports.
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