EXHIBIT 10.12 		 		 		 		 		 		 		 AMENDMENT TO TOLL MANUFACTURING AGREEMENT 	 AGREEMENT dated as of this day of December, 1994 between PUREPAC PHARMACEUTICAL CO., a Delaware Corporation, having its principal office at 200 Elmora Avenue, Elizabeth, NJ 07207 ("Purepac"), and FAULDING INC., a Delaware corporation, having its office at 274 Riverside Avenue, Westport, CT 06880 ("Faulding"). 	 WHEREAS, the parties have entered into a Toll Manufacturing Agreement (the "Manufacturing Agreement") dated as of August 1, 1993, providing for the manufacture by Purepac and the purchase by Faulding of certain pharmaceutical products as contemplated therein; and 	 WHEREAS, the parties wish to amend certain provisions of the Manufacturing Agreement; 	 NOW, THEREFORE, in consideration of the foregoing and the mutual agreements contained herein, the parties hereto agree as follows: 	 1. The percentage "one hundred twenty percent (120%)" set forth in Section 1.4 of the Manufacturing Agreement shall be changed to "one hundred twenty-five percent (125%)". 	 2. The percentage "eighty percent (80%)" set forth in Section 1.5 of the Manufacturing Agreement shall be changed to "seventy-five percent (75%)". 	 3. The word "Kapanol" appearing in Section 1.15 of the Manufacturing Agreement shall be changed to "Kadian". 	 4. Section 1.17 of the Manufacturing Agreement is hereby amended to add to the end of such Section the words "and its territories and possessions, including without limitation Puerto Rico". 	 5. Section 16.1 of the Manufacturing Agreement is hereby deleted in its entirety and replaced with the following: 	 "16.1 Subject to any other provision hereof, this Agreement shall 	 remain in effect until December 31, 2010, and the term of this 	 Agreement shall automatically be renewed thereafter for up to four 	 successive five-year terms unless notice is given by Faulding to 	 Purepac at least six months prior to the date of any such renewal 	 of Faudling's desire not to renew such term. In addition to the 	 foregoing, at any time after December 31, 2010, this Agreement 	 may be terminated by Faulding upon not less than 24 months' 	 written notice to Purepac." 	 6. Section 16.2 of the Manufacturing Agreement is hereby deleted in its entirety and replaced with the following: 	 "16.2 The obligations of the parties set forth in this Agreement 	 may be terminated by notice in writing by either party (i) if the 	 other party shall default in the performance of any of its 	 obligations under this Agreement and such default shall continue 	 for a period of not less than sixty (60) days after written notice 	 specifying such default shall have been given, or (ii) the other 	 makes an arrangement with its creditors or goes into receivership 	 or liquidation, or if a receiver and manager is appointed in 	 respect of the whole or part of the property or business of such 	 other party." 	 7. Except as and to the extent specifically amended hereby, the Manufacturing Agreement shall remain in full force and effect. 	 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the day and date first set forth above. FAULDING INC. PUREPAC PHARMACEUTICAL CO. By: /s/ By: /s/ _______________________________ _____________________________ Michael R.D. Ashton, President Robert H. Burr, President