Exhibit 24.1



                               POWER OF ATTORNEY



     KNOW ALL MEN BY THESE PRESENTS THAT the undersigned directors and officers
of McKesson HBOC, Inc., a Delaware corporation (the "Company"), do hereby
constitute and appoint Ivan D. Meyerson and Nancy A. Miller his or her true and
lawful attorney and agent, each with full power and authority (acting alone and
without the other) to execute in the name and on behalf of the undersigned as
such director and/or officer, a Registration Statement on Form S-8 under the
Securities Act of 1933, as amended, with respect to the registration of shares
of the Company's Common Stock that may be issued in connection with the
assumption of stock option plans and employee stock purchase plans of HBO &
Company in accordance with the terms of the Merger Agreement dated October 17,
1998 as amended November 9, 1998, among HBO & Company, McKesson Merger Sub, Inc.
and McKesson Corporation, and to execute any and all amendments to such
Registration Statement, whether filed prior or subsequent to the time such
Registration Statement becomes effective. The undersigned hereby grants unto
such attorneys and agents, and each of them, full power of substitution and
revocation in the premises and hereby ratifies and confirms all that such
attorneys and agents may do or cause to be done by virtue of these presents.


SIGNATURE                                     TITLE
- ---------                                     -----

/s/ Mark A. Pulido
________________________          President, Chief Executive Officer and 
    Mark A. Pulido                Director (principal executive officer)

/s/ Charles W. McCall
________________________          Chairman of the Board of Directors
    Charles W. McCall             and Director

/s/ Richard H. Hawkins
________________________          Senior Vice President and Chief Financial 
    Richard H. Hawkins            Officer (principal financial officer)
 
/s/ Heidi E. Yodowitz
________________________          Controller
    Heidi E. Yodowitz             (principal accounting officer)

/s/ Alfred C. Eckert III
________________________          Director
    Alfred C. Eckert III

/s/ Tully M. Friedman
________________________          Director
    Tully M. Friedman

/s/ Alton F. Irby III
________________________          Director
    Alton F. Irby III

/s/ Gerald E. Mayo
________________________          Director
    Gerald E. Mayo

/s/ James V. Napier
________________________          Director
    James V. Napier


/s/ Carl E. Reichardt 
________________________          Director
    Carl E. Reichardt

/s/ Alan Seelenfreund
________________________          Director
    Alan Seelenfreund

/s/ Jane E. Shaw
________________________          Director
    Jane E. Shaw

 



Dated:    January 12, 1999