SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549

                                    FORM 10-Q

                QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(D)
                     OF THE SECURITIES EXCHANGE ACT OF 1934

                  FOR THE QUARTERLY PERIOD ENDED JUNE 30, 2001

                         COMMISSION FILE NUMBER 0-26224

                    INTEGRA LIFESCIENCES HOLDINGS CORPORATION
             (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)

           DELAWARE                                               51-0317849
(STATE OR OTHER JURISDICTION OF                                (I.R.S. EMPLOYER
INCORPORATION OR ORGANIZATION)                               IDENTIFICATION NO.)


                          311 ENTERPRISE DRIVE
                      PLAINSBORO, NEW JERSEY              08536
           (ADDRESS OF PRINCIPAL EXECUTIVE OFFICES)     (ZIP CODE)

                                 (609) 275-0500
              (REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE)

               INDICATE BY CHECK MARK WHETHER THE REGISTRANT: (1)
              HAS FILED ALL REPORTS REQUIRED TO BE FILED BY SECTION
                  13 OR 15(D) OF THE SECURITIES EXCHANGE ACT OF
                1934 DURING THE PRECEDING 12 MONTHS (OR FOR SUCH
               SHORTER PERIOD THAT THE REGISTRANT WAS REQUIRED TO
                      FILE SUCH REPORTS), AND (2) HAS BEEN
                       SUBJECT TO SUCH FILING REQUIREMENTS
                              FOR THE PAST 90 DAYS.
                               /X/ - YES / / - NO

   AS OF AUGUST 13, 2001 THE REGISTRANT HAD OUTSTANDING 25,590,875 SHARES OF
                         COMMON STOCK, $.01 PAR VALUE.

                                       1



                    INTEGRA LIFESCIENCES HOLDINGS CORPORATION

                                      INDEX


                                                                     Page Number
                                                                     -----------


PART I.  FINANCIAL INFORMATION

Item 1.  Financial Statements

Consolidated Balance Sheets as of June 30, 2001 (Unaudited)
  and December 31, 2000                                                        3

Consolidated Statements of Operations for the three and
  six months ended June 30, 2001 and 2000 (Unaudited)                          4

Consolidated Statements of Cash Flows for the six months ended
  June 30, 2001 and 2000 (Unaudited)                                           5

Notes to Unaudited Consolidated Financial Statements                           6

Item 2.  Management's Discussion and Analysis of Financial Condition
  and Results of Operations                                                   13


PART II. OTHER INFORMATION

Item 2.  Changes in Securities and Use of Proceeds                            22

Item 4.  Submission of Matters to a Vote of Security Holders                  22

Item 6.  Exhibits and Reports on Form 8-K                                     22


SIGNATURES                                                                    23

                                       2



PART I.  FINANCIAL INFORMATION

Item 1.  Financial Statements

           INTEGRA LIFESCIENCES HOLDINGS CORPORATION AND SUBSIDIARIES
                           CONSOLIDATED BALANCE SHEETS


In thousands, except per share amounts

                                                        June 30,    December 31,
                                                          2001         2000
                                                        ---------   -----------
                                                       (Unaudited)
ASSETS
Current Assets:
  Cash and cash equivalents ..........................  $   8,602     $  14,086
  Short-term investments .............................      3,053         1,052
  Accounts receivable, net of allowances of
    $1,512 and $1,003 ................................     15,032        13,087
  Inventories ........................................     22,651        16,508
  Prepaid expenses and other current assets ..........      1,106         1,484
                                                        ---------     ---------
      Total current assets ...........................     50,444        46,217
 Property, plant, and equipment, net .................     11,537        11,599
 Goodwill and other intangible assets, net ...........     29,558        25,299
 Other assets ........................................      2,654         3,399
                                                        ---------     ---------
Total assets .........................................  $  94,193     $  86,514
                                                        =========     =========

LIABILITIES AND STOCKHOLDERS' EQUITY
Current Liabilities:
  Short-term debt ....................................  $   7,189     $   8,872
  Accounts payable, trade ............................      3,601         3,363
  Income taxes payable ...............................      1,266         1,200
  Customer advances and deposits .....................      2,358           823
  Deferred revenue ...................................        967         1,675
  Accrued expenses and other current liabilities .....      6,764         5,107
                                                        ---------     ---------
      Total current liabilities ......................     22,145        21,040

 Long-term debt ......................................      2,514         4,758
 Deferred revenue ....................................      4,358         4,728
 Deferred income taxes ...............................      2,278         1,788
 Other liabilities ...................................        376           419
                                                        ---------     ---------
Total liabilities ....................................     31,671        32,733

Commitments and contingencies

Stockholders' Equity:
  Preferred stock; $0.01 par value; 15,000 authorized
    shares; 0 and 100 Series B Convertible shares
    issued and outstanding at June 30, 2001 and
    December 31, 2000, respectively; 54 Series C
    Convertible shares issued and outstanding at
    June 30, 2001 and December 31, 2000, $6,075
    including a 10% annual cumulative dividend
    liquidation preference ...........................          1             2
  Common stock; $0.01 par value; 60,000 authorized
    shares; 20,745 and 17,334 issued and outstanding
    at June 30, 2001 and December 31, 2000,
    respectively .....................................        207           173
  Additional paid-in capital .........................    164,707       160,134
  Treasury stock, at cost; 20 shares at June 30, 2001
    and December 31, 2000 ............................       (180)         (180)
  Other ..............................................        (51)          (66)
  Accumulated other comprehensive loss ...............     (1,191)         (553)
  Accumulated deficit ................................   (100,971)     (105,729)
                                                        ---------     ---------
    Total stockholders' equity .......................     62,522        53,781
                                                        ---------     ---------
 Total liabilities and stockholders' equity ..........  $  94,193     $  86,514
                                                        =========     =========


               The accompanying notes are an integral part of the
                       consolidated financial statements

                                       3



           INTEGRA LIFESCIENCES HOLDINGS CORPORATION AND SUBSIDIARIES
                      CONSOLIDATED STATEMENTS OF OPERATIONS
                                   (UNAUDITED)

(In thousands, except per share amounts)



                                                        Three Months Ended June 30,     Six Months Ended June 30,
                                                        ---------------------------     -------------------------
                                                         2001              2000            2001          2000
                                                         ----              ----            ----          ----
                                                                                           
REVENUES

Product sales ....................................      $21,385          $15,827         $41,669       $29,159
Other revenue ....................................        1,535            1,259           2,935         2,458
                                                        -------          -------         -------       -------
         Total revenues ..........................       22,920           17,086          44,604        31,617

COSTS AND EXPENSES

Cost of product sales.............................        8,310            7,212          16,904        13,899
Research and development .........................        1,837            2,004           3,910         3,894
Selling and marketing ............................        5,269            3,904          10,020         6,853
General and administrative .......................        3,319            3,884           6,523         7,631
Amortization .....................................          729              670           1,409         1,150
                                                        -------          -------         -------       -------
         Total costs and expenses ................       19,464           17,674          38,766        33,427

Operating income (loss)...........................        3,456             (588)          5,838        (1,810)

Interest income ..................................          108              141             315           432
Interest expense .................................         (222)            (320)           (507)         (600)
Gain on disposition of product line ..............          --             1,031             --          1,146
Other income (expense), net ......................         (151)               9            (213)          132
                                                        -------          -------         -------       -------
Income (loss) before income taxes ................        3,191              273           5,433          (700)
Income tax expense ...............................          429              161             675           223
                                                        -------          -------         -------       -------
Income (loss) before accounting change............        2,762              112           4,758          (923)
Cumulative effect of accounting change............          --               --              --           (470)
                                                        -------          -------         -------       -------
Net income (loss) ................................      $ 2,762          $   112         $ 4,758       $(1,393)
                                                        =======          =======         =======       =======

Earnings (loss) per share:

   Basic net income (loss) per share before
     accounting change............................      $  0.12          $ (0.02)        $  0.20       $ (0.33)
   Accounting change..............................          --               --              --          (0.03)
                                                        -------          -------         -------       -------
   Basic net income (loss) per share                    $  0.12          $ (0.02)        $  0.20       $ (0.36)

   Diluted net income (loss) per share before
     accounting change............................      $  0.10          $ (0.02)        $  0.18       $ (0.33)
   Accounting change..............................          --               --              --          (0.03)
                                                        -------          -------         -------       -------
   Diluted net income (loss) per share                  $  0.10          $ (0.02)        $  0.18       $ (0.36)

Weighted average common shares outstanding:
   Basic..........................................       20,245           17,341          19,931        17,282
   Diluted........................................       25,049           17,341          22,211        17,282


               The accompanying notes are an integral part of the
                       consolidated financial statements

                                       4



           INTEGRA LIFESCIENCES HOLDINGS CORPORATION AND SUBSIDIARIES
                      CONSOLIDATED STATEMENTS OF CASH FLOWS
                                   (UNAUDITED)

(In thousands)
                                                             Six Months Ended
                                                                  June 30,
                                                            -------------------
                                                              2001       2000
                                                            --------   --------

OPERATING ACTIVITIES:

    Net income (loss) ....................................  $  4,758   $ (1,393)
    Adjustments to reconcile net income (loss)
    to net cash provided by (used in) operating
    activities:
       Depreciation and amortization .....................     2,855      2,444
       Gain on sale of product line ......................        --     (1,146)
       Other, net ........................................        82       (211)
       Changes in assets and liabilities, net of
       business acquisitions:
          Accounts receivable ............................    (1,492)    (1,147)
          Inventories ....................................    (5,406)    (1,761)
          Prepaid expenses and other current assets ......       605         28
          Non-current assets .............................       642       (561)
          Accounts payable, accrued expenses and
          other liabilities ..............................       520         11
          Customer advances and deposits .................     1,535     (1,364)
          Deferred revenue ...............................    (1,115)         7
                                                            --------   --------
       Net cash provided by (used in) operating
       activities ........................................     2,984     (5,093)
                                                            --------   --------
INVESTING ACTIVITIES:

    Proceeds from sale of product line and
    other assets .........................................        --      1,600
    Proceeds from sale/maturity of investments ...........     1,000     16,072
    Purchases of available-for-sale investments ..........    (2,891)   (14,928)
    Cash used in business acquisition,
    net of cash acquired .................................    (5,899)   (15,712)
    Purchases of property and equipment ..................    (1,168)    (2,223)
                                                            --------   --------
       Net cash used in investing activities .............    (8,958)   (15,191)
                                                            --------   --------
FINANCING ACTIVITIES:

    Net proceeds from revolving credit facility ..........       747      1,008
    Repayments of term loan ..............................    (3,203)    (1,000)
    Repayment of note payable ............................    (1,540)        --
    Proceeds from sale of preferred stock ................        --      5,375
    Proceeds from stock option and warrant exercises .....     4,533      1,429
    Treasury stock purchases .............................        --       (130)
    Collection of related party note receivable ..........        --         36
    Preferred dividends paid .............................        --        (40)
                                                            --------   --------
       Net cash provided by financing activities .........       537      6,678
                                                            --------   --------

Effect of exchange rate changes on cash and
cash equivalents .........................................       (47)       (19)

Net decrease in cash and cash equivalents ................    (5,484)   (13,625)

Cash and cash equivalents at beginning of period .........    14,086     19,301
                                                            --------   --------
Cash and cash equivalents at end of period ...............  $  8,602   $  5,676
                                                            ========   ========

Non-cash investing and financing activities:

     Business acquisition costs accrued in liabilities ...  $    716   $    634
     Note issued in a business acquisition ...............        --      2,654

               The accompanying notes are an integral part of the
                       consolidated financial statements

                                       5



           INTEGRA LIFESCIENCES HOLDINGS CORPORATION AND SUBSIDIARIES
              NOTES TO UNAUDITED CONSOLIDATED FINANCIAL STATEMENTS
                                   (UNAUDITED)


1.   BASIS OF PRESENTATION

In the  opinion of  management,  the June 30  unaudited  consolidated  financial
statements  contain  all  adjustments   (consisting  only  of  normal  recurring
accruals) which the Company  considers  necessary for a fair presentation of the
financial  position and results of operations of the Company.  Operating results
for the  periods  ended  June 30,  2001 are not  necessarily  indicative  of the
results to be expected for the entire  year.  Certain  information  and footnote
disclosures  normally  included in financial  statements  prepared in accordance
with generally accepted accounting principles have been condensed or omitted.

The preparation of financial  statements in conformity  with generally  accepted
accounting principles requires management to make estimates and assumptions that
affect the reported amounts of assets and liabilities,  including disclosures of
contingent  assets and  liabilities  and the  reported  amounts of revenues  and
expenses  during the reporting  periods.  Actual results could differ from those
estimates.

As of December 31,  2000,  the Company had  provided a $44.8  million  valuation
allowance against its consolidated  deferred tax asset due to the uncertainty of
its realization.  Because the Company has generated taxable income during recent
quarters,  management is continuing to reassess the potential  realizability  of
this asset through the generation of future taxable  income.  The recognition of
the deferred tax asset could affect the  Company's  income tax  provision in the
near term.

These unaudited  consolidated financial statements should be read in conjunction
with the Company's consolidated financial statements for the year ended December
31, 2000 included in the Company's Annual Report on Form 10-K/A.

Certain  prior year amounts have been  reclassified  to conform with the current
year's presentation.


2.   ACQUISITIONS

On April 27, 2001, the Company  acquired  Satelec  Medical,  a subsidiary of the
Satelec-Pierre  Rolland  group,  for $3.8 million in cash, of which $3.6 million
was paid at closing. Satelec Medical, based in France,  manufactures and markets
the Dissectron(R)  ultrasonic  surgical  aspirator console and a line of related
handpieces. The Dissectron(R) product has United States FDA 510(k) clearance for
neurosurgical  applications  and CE Mark  Certification  in the European  Union.
Revenues of the acquired business were approximately $1.5 million in 2000.

On April 4, 2001, the Company  acquired GMSmbH,  the German  manufacturer of the
LICOX(R) Brain Tissue Oxygen Monitoring System,  for $2.9 million.  The purchase
price consisted of $2.3 million in cash paid at closing, the forgiveness of $0.2
million in notes  receivable  from GMSmbH,  and $0.4  million of future  minimum
royalty payments to the seller. Prior to the acquisition,  the Company's Integra
NeuroSciences  division had exclusive  marketing rights to the LICOX(R) products
in the  United  States and  certain  other  markets.  Revenues  of the  acquired
business were approximately $1.2 million in 2000,  consisting primarily of sales
of the LICOX(R) products in Germany and to various  international  distributors,
including Integra.

                                       6



These  acquisitions  have  been  accounted  for  using  the  purchase  method of
accounting,  and the results of operations of the acquired  businesses have been
included in the consolidated  financial  statements since their respective dates
of  acquisition.  The  preliminary  allocation  of the purchase  price for these
acquisitions  resulted in  approximately  $6.2  million of  acquired  intangible
assets and residual goodwill, which are being amortized on a straight-line basis
over lives ranging from 5 to 15 years.

The  following  unaudited  pro  forma  financial  information  assumes  that the
acquisitions  had  occurred as of the  beginning  of each period (in  thousands,
except per share data):

                                                       For the Six Months
                                                         Ended June 30,
                                                        2001        2000
                                                      -------     -------
       Total revenue .............................    $45,018     $32,940
       Net income(loss) ..........................      4,556      (1,777)

       Net income (loss) per share:
          Basic ..................................    $  0.19     $ (0.38)
          Diluted.................................    $  0.17     $ (0.38)

The pro forma  results  do not  necessarily  represent  results  that would have
occurred if the acquisition had taken place on the basis assumed above,  nor are
they indicative of the results of future combined operations.


3.   NEW ACCOUNTING PRONOUNCEMENTS

In July 2001,  the Financial  Accounting  Standards  Board issued  Statements of
Financial Accounting Standards No. 141, BUSINESS  COMBINATIONS  (Statement 141),
and No.  142,  GOODWILL  AND OTHER  INTANGIBLE  ASSETS  (Statement  142).  These
Statements  change the  accounting  for  business  combinations,  goodwill,  and
intangible assets. Statement 141 eliminates the  pooling-of-interests  method of
accounting for business combinations except for qualifying business combinations
that were initiated prior to July 1, 2001.  Statement 141 further  clarifies the
criteria  to  recognize   intangible  assets   separately  from  goodwill.   The
requirements of Statement 141 are effective for any business combination that is
completed after June 30, 2001.

Under  Statement 142,  goodwill and indefinite  lived  intangible  assets are no
longer  amortized  but are reviewed  annually (or more  frequently if impairment
indicators  arise) for  impairment.  Separable  intangible  assets  that are not
deemed to have an  indefinite  life will  continue  to be  amortized  over their
useful lives. Goodwill and intangible assets acquired prior to July 1, 2001 will
continue  to be  amortized  through  December  31,  2001 for all  calendar  year
companies.   After  December  31,  2001,  such  goodwill  and  indefinite  lived
intangible assets will cease being amortized. Management is reviewing the impact
of these two statements on the Company's consolidated financial statements.

In  December  1999 (as  amended  in March  2000 and June  2000) the staff of the
Securities and Exchange  Commission (SEC) issued Staff Accounting  Bulletin 101,
Revenue  Recognition (the "SAB").  As the result of the adoption of the SAB, the
Company recorded a $470,000 cumulative effect of an accounting change to defer a
portion of a nonrefundable,  up-front fee received and recorded in other revenue
in 1998.  The  cumulative  effect of this  accounting  change was  measured  and
recorded as of January 1, 2000.

In June 1998, the Financial Accounting Standards Board issued Statement No. 133,
"Accounting for Derivative  Instruments and Hedging  Activities."  Statement No.
133,  as amended  by  Statement  No.  138  "Accounting  for  Certain  Derivative
Instruments and Certain Hedging Activities," requires companies to recognize all
derivatives  as either  assets or  liabilities  in the balance sheet and measure
such instruments at fair value.  The Company's  adoption of Statement No. 133 as
of January 1, 2001 did not have a material  impact on the  Company's  results of
operations or financial position.

                                       7



4.   INCOME (LOSS) PER SHARE

Basic and diluted net income (loss) per share for the periods ended June 30 were
as follows:

(In thousands, except per share amounts)



                                                     Three Months Ended June 30,       Six Months Ended June 30,
                                                     ---------------------------       -------------------------
                                                        2001            2000            2001             2000
                                                      -------         --------         -------          -------
                                                                                            
Basic net income (loss) per share:
  Net income (loss) ..............................    $ 2,762         $    112         $ 4,758          $(1,393)
  Dividends on preferred stock ...................       (371)            (405)           (756)            (675)
  Beneficial conversion feature preferred stock...        --               --              --            (4,170)
                                                      -------         --------         -------          -------
    Net income (loss) applicable to common stock..    $ 2,391         $   (293)        $ 4,002          $(6,238)

    Basic net income (loss) per share ............    $  0.12         $  (0.02)        $  0.20          $ (0.36)
                                                      =======         ========         =======          =======

Diluted net income (loss) per share:
  Net income (loss) ..............................    $ 2,762         $    112         $ 4,758          $(1,393)
  Dividends on preferred stock ...................       (135)            (405)           (756)            (675)
  Beneficial conversion feature preferred stock...        --               --              --            (4,170)
                                                      -------         --------         -------          -------
    Net income (loss) applicable to common stock..    $ 2,627         $   (293)        $ 4,002          $(6,238)

    Diluted net income (loss) per share ..........    $  0.10         $  (0.02)        $  0.18          $ (0.36)
                                                      =======         ========         =======          =======

Weighted average shares outstanding:
    Basic.........................................     20,245           17,341          19,931           17,282
    Effect of dilutive securities:
        Options and warrants......................      2,330              --            2,280              --
        Preferred stock...........................      2,474              --              --               --
                                                      -------         --------         -------          -------
    Diluted.......................................     25,049           17,341          22,211           17,282
                                                      =======         ========         =======          =======


For the three and six month periods ended June 30, 2001,  the Series C Preferred
Stock  convertible  into 600,000  shares of common stock was not included in the
computation  of diluted net income per share  because its effect would have been
antidilutive.  Prior to its  conversion on June 26, 2001, the Series B Preferred
Stock  convertible into 2,617,800 shares of common stock was not included in the
computation  of diluted  net income per share for the six months  ended June 30,
2001  because its effect would have been  antidilutive.  Options and warrants to
purchase  4,365,816 shares of common stock and preferred stock  convertible into
3,467,800  shares of common  stock at June 30,  2000  were not  included  in the
computation  of diluted  net loss per share for the three and six  months  ended
June 30, 2000 because their effect would have been antidilutive.

In  connection  with the  issuance of 54,000  shares of Series C  Preferred  and
common  stock  warrants in March  2000,  the  Company  reflected a $4.2  million
nonrecurring,  non-cash dividend related to the beneficial conversion feature of
the Series C Preferred in the  calculation  of net loss per share  applicable to
common  stock for the six month  period  ended  June 30,  2000.  The  beneficial
conversion  feature  is based  upon the  excess of the  price of the  underlying
common  stock  as  compared  to the  fixed  conversion  price  of the  Series  C
Preferred,  after  taking into  account the value  assigned to the common  stock
warrants.

                                       8



5.   COMPREHENSIVE INCOME (LOSS)

Comprehensive income (loss) for the periods ended June 30 was as follows:

(In thousands)



                                                     Three Months Ended June 30,       Six Months Ended June 30,
                                                     ---------------------------       -------------------------
                                                        2001             2000            2001             2000
                                                      --------         --------        --------         --------
                                                                                            
    Net income (loss) .........................       $ 2,762          $   112         $ 4,758          $(1,393)
    Foreign currency translation adjustment....          (414)            (338)           (745)            (338)
    Unrealized gain (loss) on investments .....            26               (7)             12              117
    Reclassification for Other than temporary
       decline in value of available for sale
       securities..............................            95               --              95              --
                                                      --------         --------        --------         --------
    Comprehensive income (loss) ...............       $ 2,469          $  (233)        $ 4,120          $(1,614)
                                                      ========         ========        ========         ========


6.   INVENTORIES

Inventories consist of the following:
                                                      June 30,      December 31,
                                                        2001            2000
                                                      --------        --------
(In thousands)
   Raw materials..............................         $ 7,248        $ 5,805
   Work-in process............................           4,361          3,825
   Finished goods.............................          11,042          6,878
                                                       -------        -------
                                                       $22,651        $16,508
                                                       =======        =======

7.   STOCKHOLDERS' EQUITY

In March 2001,  warrants to purchase 240,000 shares of common stock at $3.82 per
share were exercised, for which the Company received proceeds of $916,800.

On June 26, 2001, all of the holders of the Company's  Series B Preferred  stock
converted their 100,000 shares of Series B Preferred Stock into 2,617,800 shares
of common stock.

                                       9



8.   SEGMENT AND GEOGRAPHIC REPORTING

The Company's reportable business segments consist of the Integra  NeuroSciences
division, which is a leading provider of implants,  devices and monitors used in
neurosurgery,   neurotrauma,   and  related   critical  care,  and  the  Integra
LifeSciences  division,  which  develops and  manufactures  a variety of medical
products and devices,  including  products  based on the  Company's  proprietary
tissue  regeneration  technology,  which  are  used  to  treat  soft-tissue  and
orthopedic  conditions.  Integra  NeuroSciences sells primarily through a direct
sales organization,  and Integra  LifeSciences sells primarily through strategic
alliances and  distributors.  The Company has reclassified  certain items within
its  segments  to conform to the current  methodology  for  determining  segment
profitability.  These reclassifications were not material and did not change the
basic nature of the business  segments.  Selected  financial  information on the
Company's business segments is reported below (in thousands):

                                          Integra     Integra      Total
                                           Neuro-       Life     Reportable
                                          Sciences    Sciences    Segments
                                          --------    --------    --------
                                                   (in thousands)
     Three months ended June 30, 2001
     ----
     Product sales ....................   $ 15,724    $  5,661    $ 21,385
     Total revenue ....................     16,002       6,918      22,920
     Operating expenses ...............     12,295       4,667      16,962
     Operating income .................      3,707       2,251       5,958

     Depreciation included in segment
        operating expenses ............        373         257         630

     Three months ended June 30, 2000
     ----
     Product sales ....................   $ 11,138    $  4,689    $ 15,827
     Total revenue ....................     11,416       5,670      17,086
     Operating expenses ...............      9,792       4,902      14,694
     Operating income .................      1,624         768       2,392

     Depreciation included in segment
        operating expenses ............        299         326         625

     Six months ended June 30, 2001
     ----
     Product sales ....................   $ 30,203    $ 11,466    $ 41,669
     Total revenue ....................     30,759      13,845      44,604
     Operating expenses ...............     23,648       9,869      33,517
     Operating income .................      7,111       3,976      11,087

     Depreciation included in segment
        operating expenses ............        790         519       1,309

     Six months ended June 30, 2000
     ----
     Product sales ....................   $ 19,958    $  9,201    $ 29,159
     Total revenue ....................     20,514      11,103      31,617
     Operating expenses ...............     17,807       9,605      27,412
     Operating income .................      2,707       1,498       4,205

     Depreciation included in segment
        operating expenses ............        559         611       1,170

                                       10



A reconciliation  of the amounts  reported for total reportable  segments to the
consolidated financial statements is as follows:



                                             Three Months Ended June 30,    Six Months Ended June 30,
                                                2001            2000          2001            2000
                                              --------        --------      --------        --------
                                                                  (in thousands)
                                                                                
  Operating expenses:
  Total reportable segments ............      $ 16,962        $ 14,694      $ 33,517        $ 27,412
  Plus: Corporate general and
           administrative expenses .....         1,773           2,310         3,840           4,865
        Amortization ...................           729             670         1,409           1,150
                                              --------        --------      --------        --------
  Consolidated total operating expenses.      $ 19,464        $ 17,674      $ 38,766        $ 33,427

  Operating income (loss):
  Total reportable segments ............      $  5,958        $  2,392        11,087           4,205
  Less: Corporate general and
           administrative expenses .....         1,773           2,310         3,840           4,865
        Amortization ...................           729             670         1,409           1,150
                                              --------        --------      --------        --------
  Consolidated operating income (loss)..      $  3,456        $   (588)     $  5,838        $ (1,810)


Product sales consisted of the following:
                                              Three Months Ended June 30,
                                                  2001           2000
                                                --------       --------
                                                     (in thousands)
     Integra NeuroSciences:
        Neuro intensive care unit..........     $  6,811       $  5,549
        Neuro operating room...............        8,913          5,589
                                                --------       --------
        Total product sales................       15,724         11,138

     Integra LifeSciences:
        Private label products.............        3,330          2,713
        Distributed products...............        2,331          1,976
                                                --------       --------
        Total product sales................        5,661          4,689

     Consolidated product sales............     $ 21,385       $ 15,827


                                               Six Months Ended June 30,
                                                  2001           2000
                                                --------       --------
                                                     (in thousands)
     Integra NeuroSciences:
        Neuro intensive care unit..........     $ 13,344       $ 11,081
        Neuro operating room...............       16,859          8,877
                                                --------       --------
        Total product sales................       30,203         19,958

     Integra LifeSciences:
        Private label products.............        6,773          5,434
        Distributed products...............        4,693          3,767
                                                --------       --------
        Total product sales................       11,466          9,201

     Consolidated product sales............     $ 41,669       $ 29,159

                                       11



Product sales by major geographic area are summarized below:



                                          United                   Asia       Other
                                          States      Europe     Pacific     Foreign      Total
                                         --------    --------    --------    --------    --------
(in thousands)

                                                                          
Three months ended June 30, 2001.....    $ 16,819    $  2,330    $  1,390    $    846    $ 21,385
Three months ended June 30, 2000.....    $ 12,340    $  1,870    $  1,073    $    544    $ 15,827

Six months ended June 30, 2001.......    $ 32,750    $  4,714    $  2,505    $  1,700    $ 41,669
Six months ended June 30, 2000.......    $ 22,928    $  2,951    $  2,343    $    937    $ 29,159



9.   LEGAL MATTERS

In July  1996,  we filed a patent  infringement  lawsuit  in the  United  States
District  Court for the Southern  District of  California  against Merck KGaA, a
German  corporation,   Scripps  Research  Institute,   a  California   nonprofit
corporation,  and David A. Cheresh,  Ph.D.,  a research  scientist with Scripps,
seeking  damages and  injunctive  relief.  The  complaint  charged,  among other
things,  that the defendant Merck KGaA willfully and deliberately  induced,  and
continues to willfully and  deliberately  induce,  defendants  Scripps  Research
Institute  and Dr.  David A. Cheresh to infringe  certain of our patents.  These
patents  are part of a group of patents  granted to The  Burnham  Institute  and
licensed  by us that  are  based on the  interaction  between  a family  of cell
surface proteins called integrins and the arginine-glycine-aspartic acid peptide
sequence found in many  extracellular  matrix  proteins.  The defendants filed a
countersuit  asking for an award of defendants'  reasonable  attorney fees. This
case went to trial in February  2000,  and on March 17, 2000, a jury  returned a
unanimous  verdict for us finding that Merck KGaA had  willfully  infringed  and
induced the infringement of our patents, and awarded $15,000,000 in damages. The
court  dismissed  Scripps and Dr. Cheresh from the case. On October 6, 2000, the
United States  District  Court for the Southern  District of California  entered
judgment  in our favor and  against  Merck  KGaA in the case.  In  entering  the
judgment,  the court also  granted us  pre-judgment  interest  of  approximately
$1,350,000,  bringing  the  total  amount  to  approximately  $16,350,000,  plus
post-judgment  interest.  Various  post-trial  motions are pending,  including a
request  by Merck  KGaA for a judgment  as a matter of law  notwithstanding  the
verdict,  which could have the effect of reducing the judgment or reversing  the
verdict of the jury. In addition,  if we win these post-trial motions, we expect
Merck  KGaA to appeal  various  decisions  of the  Court.  No  amounts  for this
favorable verdict have been reflected in our financial statements.

We are also subject to other  claims and lawsuits in the ordinary  course of our
business, including claims by employees and with respect to our products. In the
opinion  of  management,  the other  claims  are  either  adequately  covered by
insurance or otherwise indemnified, and are not expected, individually or in the
aggregate,  to result in a material  adverse effect on our financial  condition.
Our financial statements do not reflect any material amounts related to possible
unfavorable  outcomes of the matters  above or others.  However,  it is possible
that these  contingencies  could  materially  affect our results of  operations,
financial position and cash flows in a particular period.


10.  SUBSEQUENT EVENT

On August 13, 2001,  the Company  issued  4,747,500  shares of common stock in a
public  offering at $25.50 per share for net  proceeds of  approximately  $113.8
million after deducting  expenses related to the offering.  The Company plans to
use the proceeds from the offering for general corporate  purposes,  which could
include,  among  other  things,  acquisition  of  product  lines  or  companies,
repayment of indebtedness, the expansion of sales and marketing, the development
of new technologies and increases in working capital.

                                       12



ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
         OF OPERATIONS

The  following  discussion  should  be read in  conjunction  with the  Company's
consolidated  financial  statements,  the notes thereto and the other  financial
information  included  elsewhere in this report and in the Company's 2000 Annual
Report on Form 10-K/A filed with the Securities and Exchange Commission.

OVERVIEW

The Company  develops,  manufactures and markets medical  devices,  implants and
biomaterials for the  neurosurgical,  orthopedic and soft tissue repair markets.
The Company's operations consist of:

o    Integra  NeuroSciences,  which is a leading provider of implants,  devices,
     and monitors used in neurosurgery,  neurotrauma, and related critical care;
     and

o    Integra LifeSciences,  which develops and manufactures a variety of medical
     products and devices,  including  products based on our proprietary  tissue
     regeneration  technology which are used to treat soft tissue and orthopedic
     conditions.

Integra  NeuroSciences  sells primarily through a direct sales  organization and
Integra   LifeSciences   sells  primarily   through   strategic   alliances  and
distributors.

Certain items within the Company's  business  segments have been reclassified to
conform to the current methodology for determining segment profitability.  These
reclassifications  were not  material and did not change the basic nature of the
business segments.

RECENT ACQUISITIONS

On  April  27,  2001,  we  acquired  Satelec   Medical,   a  subsidiary  of  the
Satelec-Pierre  Rolland  group,  for $3.8 million in cash, of which $3.6 million
was paid at closing. Satelec Medical, based in France,  manufactures and markets
the  Dissectron(R)  ultrasonic  surgical  aspirator  console and a broad line of
related handpieces. The Dissectron(R) product is the leading ultrasonic surgical
system in  France.  The  Dissectron(R)  product  has FDA  510(k)  clearance  for
neurosurgical  applications  and CE Mark  Certification  in the European  Union.
Revenues of the acquired business were approximately $1.5 million in 2000.

On April 4, 2001, we acquired all of the outstanding stock of GMSmbH, the German
manufacturer  of the LICOX(R) Brain Tissue Oxygen  Monitoring  System,  for $2.9
million  of  which  $2.3  million  was  paid in cash at  closing.  Prior  to the
acquisition,  our Integra NeuroSciences  division had exclusive marketing rights
to the  LICOX(R)  products  in the United  States  and  certain  other  markets.
Revenues of the acquired GMS business were  approximately  $1.2 million in 2000,
consisting primarily of sales of the LICOX(R) products in Germany and to various
international distributors, including Integra.

On April 6, 2000, we purchased the Selector(R) Ultrasonic Aspirator, Ruggles(TM)
hand-held  neurosurgical  instruments and Spembly(R) Medical cryosurgery product
lines,  including  certain assets and  liabilities,  from NMT Medical,  Inc. for
$11.6 million in cash.

On January 17, 2000,  the Company  purchased  the  business,  including  certain
assets and liabilities,  of Clinical Neuro Systems,  Inc. for $6.8 million.  CNS
designs,  manufactures and sells  neurosurgical  external  ventricular  drainage
systems,  including catheters and drainage bags, as well as cranial access kits.
The purchase  price of the CNS business  consisted of $4.0 million in cash and a
$2.8 million 5% secured  promissory  note issued to the seller.  The  promissory
note, of which approximately $1.4 million remains outstanding, is collateralized
by  inventory,  property  and  equipment of the CNS business and by a collateral
assignment of a $2.8 million promissory note from one of our subsidiaries.

                                       13



These  acquisitions  have  been  accounted  for  using  the  purchase  method of
accounting,  and our consolidated  financial  statements  include the results of
operations  of  the  acquired   businesses   since  their  respective  dates  of
acquisition. As a result of these acquisitions,  the Company's segment financial
results  for the three and six months  ended  June 30,  2001 and 2000 may not be
directly comparable.

RESULTS OF OPERATIONS

Comparison  of Three  Months  Ended June 30, 2001 to Three Months Ended June 30,
2000

Product Sales and Gross Margins on Product Sales:

                                              Three Months Ended June 30,
                                                  2001           2000
                                                --------       --------
                                                     (in thousands)
     Integra NeuroSciences:
        Neuro intensive care unit..........     $  6,811       $  5,549
        Neuro operating room...............        8,913          5,589
                                                --------       --------
        Total product sales................       15,724         11,138
        Cost of product sales..............        5,752          4,817
                                                --------       --------
        Gross margin on product sales......        9,972          6,321
        Gross margin percentage............          63%            57%

     Integra LifeSciences:
        Private label products.............        3,330          2,713
        Distributed products...............        2,331          1,976
                                                --------       --------
        Total product sales................        5,661          4,689
        Cost of product sales..............        2,558          2,395
                                                --------       --------
        Gross margin on product sales......        3,103          2,294
        Gross margin percentage............          55%            49%

     Consolidated:
     Product sales.........................     $ 21,385       $ 15,827
     Consolidated gross margin percentage..          61%            54%

In the second quarter of 2001,  total revenues  increased $5.8 million,  or 34%,
over the second  quarter of 2000 to $22.9  million.  Revenue growth was led by a
$5.6 million increase in product sales to $21.4 million, a 35% increase over the
second  quarter of 2000.  Included in this increase was $0.4 million in sales of
product  lines  acquired  in the  quarter.  Sales in the  Integra  NeuroSciences
division  increased $4.6 million to $15.7 million in the second quarter of 2001,
and included $0.4 million in sales of acquired  product lines.  Contributing  to
the  strong  growth in the  Integra  NeuroSciences  division  were  sales of the
DuraGen(R) Dural Graft Matrix, our line of intracranial  monitoring products for
the neuro intensive care unit, and the Selector(R) Integra Ultrasonic  Aspirator
for the  ablation of cranial  tumors.  For the second  quarter of 2001 and 2000,
Integra NeuroSciences' reported gross margin on product sales was reduced by one
percentage point and two percentage points, respectively, relating to fair value
inventory   purchase   accounting   adjustments   recorded  in  connection  with
acquisitions.  The  adjusted  gross  margin  on  product  sales  increased  five
percentage points to 64% in the second quarter of 2001 through an improved sales
mix of higher margin products.

Future  product  sales in the Integra  NeuroSciences  division  are  expected to
benefit from growth in the division's  existing  product lines and the launch of
new or recently developed  products,  including the LICOX(R) Brain Tissue Oxygen
Monitoring  System, the Ventrix(R) True Tech Tunneling Catheter for intracranial
pressure monitoring,  and the NeuraGen(TM) Nerve Guide for the repair of damaged
peripheral nerves.

Sales of Integra  LifeSciences  division products increased $1.0 million to $5.7
million  in the  second  quarter  of 2001  primarily  because  of  growth in the
Company's  private  label  products.  Sales of private  label  products can vary
significantly  from quarter to quarter and are dependent upon the efforts of our
strategic  marketing   partners.   For  the  second  quarter  of  2000,  Integra
LifeSciences'  reported  gross  margin  on  product  sales  was  reduced  by two
percentage

                                       14



points relating to fair value inventory purchase accounting adjustments recorded
in connection with an  acquisition.  As compared to the adjusted gross margin of
51% in the second quarter of 2000,  gross margin on product sales increased four
percentage  points to 55% in the second quarter of 2001 primarily as a result of
increased capacity utilization.

Other revenue, which increased $0.3 million to $1.5 million in the first quarter
of 2001,  consisted  of $1.1 million of research  and  development  funding from
strategic  partners and government  grants,  $0.3 million of royalty income, and
$0.1 million of license and distribution revenues.

Research and development expenses were as follows:

                                      Three Months Ended June 30,
                                          2001           2000
                                        --------       --------
                                            (in thousands)
Integra NeuroSciences.............      $   712        $   735
Integra LifeSciences..............        1,125          1,269
                                        -------        -------
   Total..........................      $ 1,837        $ 2,004
                                        =======        =======

The  future  allocation  and timing of  research  and  development  expenditures
between segments and programs will vary depending on various factors,  including
the  timing  and  outcome  of  pre-clinical  and  clinical   results,   changing
competitive  conditions,  continued  program funding levels,  potential  funding
opportunities and determinations with respect to the commercial potential of the
Company's technologies.

Selling and marketing expenses were as follows:

                                      Three Months Ended June 30,
                                          2001           2000
                                        --------       --------
                                            (in thousands)
Integra NeuroSciences.............      $ 4,784        $ 3,038
Integra LifeSciences..............          485            866
                                        -------        -------
   Total..........................      $ 5,269        $ 3,904
                                        =======        =======

Integra  NeuroSciences  selling and marketing expenses increased $1.7 million as
compared to the second quarter of 2000 primarily  because of the increase in the
size of the direct  sales force in the United  States  throughout  2000 and into
2001 from 18 to 44 neurospecialists.

Within the Integra LifeSciences division, product sales and marketing activities
are  primarily  the  responsibility  of our  strategic  marketing  partners  and
distributors.  The $0.4  million  decrease  in Integra  LifeSciences'  sales and
marketing  expenses to $0.5 million in the second  quarter of 2001  reflects the
transition of selling and  marketing  activities  to these  strategic  marketing
partners and lower distributor selling costs.

                                       15



General and administrative expenses were as follows:

                                      Three Months Ended June 30,
                                          2001           2000
                                        --------       --------
                                            (in thousands)
Integra NeuroSciences.............      $ 1,047        $ 1,202
Integra LifeSciences..............          499            372
Corporate.........................        1,773          2,310
                                        -------        -------
   Total..........................      $ 3,319        $ 3,884
                                        =======        =======

The $0.2 million decrease in Integra  NeuroSciences'  general and administrative
expenses was primarily  related to headcount  reductions in 2001 and  consulting
costs incurred in 2000 related to the CNS acquisition.

The $0.5 million decrease in corporate general and  administrative  expenses was
primarily the result of decreased legal fees.

Other income (expense), net includes the following:

                                      Three Months Ended June 30,
                                          2001           2000
                                        --------       --------
                                            (in thousands)
Other than temporary decline in
   available for sale securities..      $   (95)       $   --
Other, net........................          (56)             9
                                        -------        -------
   Total..........................      $  (151)       $     9
                                        =======        =======

The provision for income taxes  increased  $0.3 million in the second quarter of
2001 to $0.4 million,  which brings the effective tax rate for the  year-to-date
period to approximately 12.5%. The decrease in the effective rate as compared to
the second quarter of 2000 is the result of greater taxable income  generated in
2001 in  jurisdictions  where the Company has net operating  loss  carryforwards
available to offset taxable income.

Net income for the second quarter of 2001 was $2.8 million, or $0.10 per diluted
share, as compared to net income of $0.1 million for the second quarter of 2000,
or a $0.02 loss per share (after the effect of preferred stock  dividends).  The
net income for the second  quarter of 2000  includes a $1.0  million gain on the
sale of a  product  line and  $0.3  million  of fair  value  inventory  purchase
accounting adjustments. Excluding these items, the Company would have reported a
net loss of $0.6 million,  or a $0.06 per share loss,  for the second quarter of
2000.

Comparison of Six Months Ended June 30, 2001 to Six Months Ended June 30, 2000

                                       16



Product Sales and Gross Margins on Product Sales:

                                               Six Months Ended June 30,
                                                  2001           2000
                                                --------       --------
                                                     (in thousands)
     Integra NeuroSciences:
        Neuro intensive care unit..........     $ 13,344       $ 11,081
        Neuro operating room...............       16,859          8,877
                                                --------       --------
        Total product sales................       30,203         19,958
        Cost of product sales..............       11,389          8,995
                                                --------       --------
        Gross margin on product sales......       18,814         10,963
        Gross margin percentage............          62%            55%

     Integra LifeSciences:
        Private label products.............        6,773          5,434
        Distributed products...............        4,693          3,767
                                                --------       --------
        Total product sales................       11,466          9,201
        Cost of product sales..............        5,515          4,904
                                                --------       --------
        Gross margin on product sales......        5,951          4,297
        Gross margin percentage............          52%            47%

     Consolidated:
     Product sales.........................     $ 41,669       $ 29,159
     Consolidated gross margin percentage..          59%            52%

For the six months ended June 30, 2001, total revenues  increased $13.0 million,
or 41%, over the six month period ended June 30, 2000 to $44.6 million.  Revenue
growth was led by a $12.5 million increase in product sales to $41.7 million,  a
43% increase  over the six month  period  ended June 30, 2000.  Included in this
increase  was $0.4  million in sales of  product  lines  acquired  in the second
quarter  of 2001 and an  additional  three  months  of sales  of  product  lines
acquired  from NMT  Medical in April 2000.  Sales in the  Integra  NeuroSciences
division  increased $10.2 million to $30.2 million for the six months ended June
30, 2001,  and included $0.4 million in sales of product  lines  acquired in the
second  quarter of 2001 and six months of sales of product  lines  acquired from
NMT  Medical in April  2000.  Contributing  to the strong  growth in the Integra
NeuroSciences division were sales of the DuraGen(R) Dural Graft Matrix, our line
of intracranial  monitoring  products for the neuro intensive care unit, and the
Selector(R) Integra Ultrasonic Aspirator for the ablation of cranial tumors. For
the six month  periods  ended  June 30,  2001 and 2000,  Integra  NeuroSciences'
reported gross margin on product sales was reduced by one  percentage  point and
two percentage points,  respectively,  relating to fair value inventory purchase
accounting  adjustments  recorded in connection with acquisitions.  The adjusted
gross margin on product sales increased six percentage points to 63% for the six
months  ended June 30,  2001  through  an  improved  sales mix of higher  margin
products.

Sales of Integra LifeSciences  division products increased $2.3 million to $11.5
million for the six month period ended June 30, 2001 primarily because of growth
in both private label and  distributed  products.  For the six months ended June
30, 2000,  Integra  LifeSciences'  reported  gross  margin on product  sales was
reduced  by one  percentage  point  relating  to fair value  inventory  purchase
accounting  adjustments recorded in connection with an acquisition.  As compared
to the  adjusted  gross  margin of 48% for the six month  period  ended June 30,
2000, gross margin on product sales increased four percentage  points to 52% for
the six months ended June 30, 2001  primarily as a result of increased  capacity
utilization in the second quarter of 2001.

Other revenue,  which  increased $0.5 million to $2.9 million for the six months
ended June 30,  2001,  consisted  of $2.0  million of research  and  development
funding from strategic partners and government  grants,  $0.6 million of royalty
income, and $0.3 million of license and distribution revenues.

                                       17



Research and development expenses were as follows:

                                       Six Months Ended June 30,
                                          2001           2000
                                        --------       --------
                                            (in thousands)
Integra NeuroSciences.............      $ 1,400        $ 1,238
Integra LifeSciences..............        2,510          2,656
                                        -------        -------
   Total..........................      $ 3,910        $ 3,894
                                        =======        =======

The $0.2 million  increase in Integra  NeuroSciences'  research and  development
expenses to $1.4  million for the six months  ended June 30, 2001 was  primarily
related to  development  activities  for the  NeuraGen(TM)  Nerve  Guide,  which
received FDA approval in June 2001.

Selling and marketing expenses were as follows:

                                       Six Months Ended June 30,
                                          2001           2000
                                        --------       --------
                                            (in thousands)
Integra NeuroSciences.............      $ 9,022        $ 5,482
Integra LifeSciences..............          998          1,371
                                        -------        -------
   Total..........................      $10,020        $ 6,853
                                        =======        =======

Integra  NeuroSciences  selling and marketing expenses increased $3.5 million to
$9.0  million for the six months  ended June 30, 2001  primarily  because of the
increase in the size of the direct sales force in the United States.

The $0.4 million decrease in Integra  LifeSciences' sales and marketing expenses
to $1.0 million for the six months ended June 30, 2001  reflects the  transition
of selling and marketing  activities to strategic  marketing  partners and lower
distributor selling costs.

General and administrative expenses were as follows:

                                       Six Months Ended June 30,
                                          2001           2000
                                        --------       --------
                                            (in thousands)
Integra NeuroSciences.............      $ 1,837        $ 2,092
Integra LifeSciences..............          846            674
Corporate.........................        3,840          4,865
                                        -------        -------
   Total..........................      $ 6,523        $ 7,631
                                        =======        =======

The $0.3 million decrease in Integra  NeuroSciences'  general and administrative
expenses was primarily  related to headcount  reductions in 2001 and  consulting
costs incurred in 2000 related to the CNS acquisition.

The $0.2 million increase in Integra  LifeSciences'  general and  administrative
expenses was primarily related to increased headcount.

The $1.0 million decrease in corporate general and  administrative  expenses was
primarily the result of decreased legal fees.


                                       18



Other income (expense), net includes the following:

                                       Six Months Ended June 30,
                                          2001           2000
                                        --------       --------
                                            (in thousands)
Other than temporary decline in
   available for sale securities....    $   (95)       $   --
Gain on sale of available for sale
   securities.......................        --             176
Other, net..........................       (118)           (44)
                                        -------        -------
   Total............................    $  (213)       $   132
                                        =======        =======

The provision for income taxes  increased  $0.5 million for the six month period
ended June 30, 2001 to $0.7 million, which brings the effective tax rate for the
year-to-date period to approximately 12.5%.

Net income for the six months ended June 30, 2001 was $4.8 million, or $0.18 per
diluted  share,  as compared to a net loss of $1.4 million,  or $0.36 per share,
for the six  months  ended  June 30,  2000.  The net loss per  share for the six
months ended June 30, 2000 includes a $4.2 million beneficial conversion feature
associated  with the issuance of  convertible  preferred  stock and common stock
warrants in March 2000, which is treated as a non-cash dividend in computing per
share earnings.  The beneficial  conversion  feature is based upon the excess of
the price of the  underlying  common  stock as compared to the fixed  conversion
price of the convertible  preferred  stock,  after taking into account the value
assigned  to the  warrants.  Included  in the $1.4  million net loss for the six
months ended June 30, 2000 was a $0.5 million cumulative effect of an accounting
change,  $0.4 million of fair value inventory purchase  accounting  adjustments,
and a $1.1 million gain on the sale of product lines.  Excluding these items and
the $4.2 million  beneficial  conversion feature associated with the convertible
preferred  stock, the Company would have reported a $0.09 net loss per share for
the six months ended June 30, 2000.


INTERNATIONAL PRODUCT SALES AND OPERATIONS

For the six months  ended June 30, 2001,  sales to customers  outside the United
States totaled $8.9 million,  or 21% of  consolidated  product  sales,  of which
approximately  53% were to Europe.  Of this amount,  $3.0 million of these sales
were generated in foreign  currencies  from our  foreign-based  subsidiaries  in
England,  Germany and France. Our international sales and operations are subject
to the risk of foreign  currency  fluctuations,  both in terms of exchange  risk
related to  transactions  conducted in foreign  currencies  and the price of our
products in those markets for which sales are denominated in the U.S. dollar.

For the six months  ended June 30, 2000,  sales to customers  outside the United
States totaled $6.2 million,  or 21% of  consolidated  product  sales,  of which
approximately  47% were to Europe.  Of this amount,  $1.1 million of these sales
were  generated  in foreign  currencies  from our  foreign-based  subsidiary  in
England.

We seek to increase  our  presence in  international  markets,  particularly  in
Europe,  through acquisitions of businesses with an existing international sales
and marketing  infrastructure or the capacity to develop such an infrastructure.
The Company  acquired  operations in Germany and France with the acquisitions of
GMS and Satelec Medical in April 2001.


LIQUIDITY AND CAPITAL RESOURCES

To date, the Company has experienced  significant  cumulative  operating losses.
Historically, we have funded our operations primarily through private and public
offerings of equity  securities,  product  revenues,  research and collaboration
funding,  borrowings  under  a  revolving  credit  line  and  cash  acquired  in
connection with business acquisitions and dispositions.  Recently,  however, the
Company has  substantially  reduced  its cash burn rate and,  for the six months
ended June 30, 2001,  generated  positive  operating cash flows of $3.0 million.
Included in operating cash flows was a $5.4 million use of cash due to inventory
growth,  $1.5 million use of cash due to accounts  receivable growth, and a $1.5
million  source of cash from  advanced  payments and customer  deposits from our
strategic alliance partners.

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At June 30,  2001,  the  Company  had  cash,  cash  equivalents  and  short-term
investments  of  approximately  $11.7  million  and $9.7  million  in short  and
long-term debt.

The Company's  principal uses of funds during the six months ended June 30, 2001
were $5.9 million for business acquisitions, $4.7 million of debt repayments and
$1.2 million in purchases of property and equipment.  Principal sources of funds
were $3.0 million of positive operating cash flow, $0.7 million of proceeds from
short-term borrowings, and $4.5 million from the issuance of common stock.

The  Company  maintains a term loan and  revolving  credit  facility  from Fleet
Capital  Corporation  (collectively,  the  "Fleet  Credit  Facility"),  which is
collateralized  by all of the assets and  ownership  interests of various of our
subsidiaries  including Integra NeuroCare LLC, and NeuroCare Holding Corporation
(the parent company of Integra  NeuroCare LLC) has guaranteed  Integra NeuroCare
LLC's  obligations.  Integra  NeuroCare LLC is subject to various  financial and
non-financial  covenants under the Fleet Credit Facility,  including significant
restrictions  on its  ability  to  transfer  funds to the  Company  or its other
subsidiaries and restrictions on its ability to borrow more money. The financial
covenants  specify  minimum levels of interest and fixed charge coverage and net
worth,  and also  specify  maximum  levels  of  capital  expenditures  and total
indebtedness to operating cash flow, among others. While the Company anticipates
that Integra  NeuroCare  LLC will be able to satisfy the  requirements  of these
financial  covenants,  there can be no assurance that Integra NeuroCare LLC will
generate   sufficient   earnings  before  interest,   taxes,   depreciation  and
amortization  to meet the  requirements  of such  covenants.  The  term  loan is
subject to  mandatory  prepayment  amounts  if  certain  levels of cash flow are
achieved.  In April  2001,  Integra  NeuroCare  LLC prepaid  approximately  $2.1
million in principal as a result of such provisions in addition to the scheduled
quarterly principal payment.

On August 13, 2001,  the Company  issued  4,747,500  shares of common stock in a
public  offering at $25.50 per share for net  proceeds of  approximately  $113.8
million after deducting  expenses related to the offering.  The Company plans to
use the proceeds from the offering for general corporate  purposes,  which could
include,  among  other  things,  acquisition  of  product  lines  or  companies,
repayment of indebtedness, the expansion of sales and marketing, the development
of new technologies and increases in working capital. The Company expects to use
some of the proceeds to reduce or  eliminate  borrowings  under the Fleet Credit
Facility.

In the short-term, the Company believes that it has sufficient resources to fund
its operations.  In the absence of a material  acquisition or a material adverse
change in our  business,  we believe we have the ability to fund our  operations
from our existing capital resources and cash generated from the business through
the end of 2002. However, in the longer-term, there can be no assurance that the
Company  will  be able to  generate  sufficient  revenues  to  sustain  positive
operating cash flows or  profitability  or to find  acceptable  alternatives  to
finance future acquisitions.

                                       20



OTHER MATTERS

At  December  31,  2000,  the  Company had  provided a $44.8  million  valuation
allowance against its consolidated  deferred tax asset due to the uncertainty of
its realization.  Because the Company has generated taxable income during recent
quarters,  management is continuing to reassess the potential  realizability  of
this asset through the generation of future taxable  income.  The recognition of
the deferred tax asset could affect the  Company's  income tax  provision in the
near term.

New Accounting Pronouncements

In July 2001,  the Financial  Accounting  Standards  Board issued  Statements of
Financial Accounting Standards No. 141, BUSINESS  COMBINATIONS  (Statement 141),
and No.  142,  GOODWILL  AND OTHER  INTANGIBLE  ASSETS  (Statement  142).  These
Statements  change the  accounting  for  business  combinations,  goodwill,  and
intangible assets. Statement 141 eliminates the  pooling-of-interests  method of
accounting for business combinations except for qualifying business combinations
that were initiated prior to July 1, 2001.  Statement 141 further  clarifies the
criteria  to  recognize   intangible  assets   separately  from  goodwill.   The
requirements of Statement 141 are effective for any business combination that is
completed after June 30, 2001.

Under  Statement 142,  goodwill and indefinite  lived  intangible  assets are no
longer  amortized  but are reviewed  annually (or more  frequently if impairment
indicators  arise) for  impairment.  Separable  intangible  assets  that are not
deemed to have an  indefinite  life will  continue  to be  amortized  over their
useful lives. Goodwill and intangible assets acquired prior to July 1, 2001 will
continue  to be  amortized  through  December  31,  2001 for all  calendar  year
companies.   After  December  31,  2001,  such  goodwill  and  indefinite  lived
intangible assets will cease being amortized. Management is reviewing the impact
of these two statements on the Company's consolidated financial statements.

In  December  1999 (as  amended  in March  2000 and June  2000) the staff of the
Securities and Exchange  Commission (SEC) issued Staff Accounting  Bulletin 101,
Revenue  Recognition (the "SAB").  As the result of the adoption of the SAB, the
Company recorded a $470,000 cumulative effect of an accounting change to defer a
portion of a nonrefundable,  up-front fee received and recorded in other revenue
in 1998.  The  cumulative  effect of this  accounting  change was  measured  and
recorded as of January 1, 2000.

In June 1998, the Financial Accounting Standards Board issued Statement No. 133,
"Accounting for Derivative  Instruments and Hedging  Activities."  Statement No.
133,  as amended  by  Statement  No.  138  "Accounting  for  Certain  Derivative
Instruments and Certain Hedging Activities," requires companies to recognize all
derivatives  as either  assets or  liabilities  in the balance sheet and measure
such instruments at fair value.  The Company's  adoption of Statement No. 133 as
of January 1, 2001 did not have a material  impact on the  Company's  results of
operations or financial position.


FORWARD-LOOKING STATEMENTS

We have made statements in this report, including statements under "Management's
Discussion and Analysis of Financial  Condition and Results of Operations" which
constitute  forward-looking  statements within the meaning of Section 27A of the
Securities Act of 1933 and Section 21E of the  Securities  Exchange Act of 1934.
These forward-looking statements are subject to a number of risks, uncertainties
and  assumptions  about the  Company,  including  those  described  under  "Risk
Factors"  in the  Company's  Annual  Report on Form  10-K/A  for the year  ended
December 31, 2000 filed with the Securities and Exchange Commission. In light of
these risks and  uncertainties,  the  forward-looking  events and  circumstances
discussed  in  this  report  may not  occur  and  actual  results  could  differ
materially from those anticipated or implied in the forward-looking statements.

You can identify these forward-looking  statements by forward-looking words such
as "believe,"  "may," "could,"  "will,"  "estimate,"  "continue,"  "anticipate,"
"intend," "seek," "plan," "expect," "should," "would" and similar expressions in
this report.

                                       21



PART II.  OTHER INFORMATION

ITEM 2.   CHANGES IN SECURITIES AND USE OF PROCEEDS

On May 4,  2001,  we  notified  the  holders of the  100,000  shares of Series B
Preferred  of our  intention  to redeem  these shares on June 29, 2001 for $12.3
million.  The holders of the Series B Preferred  had the right to convert  their
shares into common stock prior to this  redemption.  As of June 26, 2001, all of
the  holders of the Series B  Preferred  exercised  this right to convert  their
100,000 shares of Series B Preferred into 2,617,800 shares of common stock.


ITEM 4.   SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

The results of matters voted on at the Company's  Annual Meeting of Stockholders
held on May 15,  2001 were  filed in a Current  Report on Form 8-K dated May 15,
2001 filed with the Securities and Exchange Commission on May 25, 2001.


ITEM 6.   EXHIBITS AND REPORTS ON FORM 8-K

(a) Exhibits

None

(b) Reports on Form 8-K

The Company filed with the Securities  and Exchange  Commission a Report on Form
8-K dated May 15, 2001 with  respect to the  results of the matters  voted on at
the Company's Annual Meeting of Stockholders held on May 15, 2001.

                                       22



                                   SIGNATURES

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized.

                    INTEGRA LIFESCIENCES HOLDINGS CORPORATION

      Date: August 14, 2001         /s/  Stuart M. Essig
                                    --------------------

                                    Stuart M. Essig
                                    President and Chief Executive Officer

      Date: August 14, 2001         /s/  David B. Holtz
                                    -------------------

                                    David B. Holtz
                                    Senior Vice President, Finance and Treasurer

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