Exhibit 32.1

                        CERTIFICATION OF CEO PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002




      In connection with the Annual Report of E. I. du Pont de Nemours and
Company (the "Company") on Form 10-K for the period ending December 31, 2003 as
filed with the Securities and Exchange Commission on the date hereof (the
"Report"), Charles O. Holliday, Jr., as Chief Executive Officer of the Company,
hereby certifies, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to
Section 906 of the Sarbanes-Oxley Act of 2002, that:

          (1)   The Report fully complies with the requirements of Section 13(a)
                of the Securities Exchange Act of 1934; and

          (2)   The information contained in the Report fairly presents, in
                all material respects, the financial condition and results of
                operations of the Company.











                                               /s/ Charles O. Holliday, Jr.
                                            ------------------------------------
                                                   Charles O. Holliday, Jr.
                                                    Chief Executive Officer
                                                         March 3, 2004