EXHIBIT 32.1

                            CERTIFICATION PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In  connection  with the Quarterly  Report of PDI, Inc. (the  "Company") on Form
10-Q for the period ending  September 30, 2004 as filed with the  Securities and
Exchange Commission on the date hereof (the "Report"),  I, Charles T. Saldarini,
Chief Executive Officer of the Company, certify, pursuant to 18 U.S.C. ss. 1350,
as adopted pursuant to ss. 906 of the Sarbanes-Oxley Act of 2002, to the best of
my knowledge, that:

      (1) The Report fully  complies with the  requirements  of section 13(a) or
15(d) of the Securities Exchange Act of 1934; and

      (2) The  information  contained  in the  Report  fairly  presents,  in all
material  respects,  the  financial  condition  and result of  operations of the
Company.

/s/ Charles T. Saldarini
- ------------------------
Charles T. Saldarini
Chief Executive Officer
November 3, 2004