EXHIBIT 32.1


                            CERTIFICATION PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002


In connection  with the Annual Report of PDI, Inc. (the  "Company") on Form 10-K
for the fiscal year ended  December  31, 2004 as filed with the  Securities  and
Exchange Commission (the "SEC") on the date hereof (the "Report"), I, Charles T.
Saldarini,  Vice Chairman and Chief Executive  Officer of the Company,  certify,
pursuant  to 18  U.S.C.  ss.  1350,  as  adopted  pursuant  to  ss.  906  of the
Sarbanes-Oxley Act of 2002, that:

       (1)    The Report fully complies with the  requirements  of section 13(a)
or 15(d) of the Securities Exchange Act of 1934; and

       (2)    The information  contained in the Report fairly  presents,  in all
material  respects,  the  financial  condition  and result of  operations of the
Company.

A signed original of this written statement has been provided to the Company and
will be  retained  by the  Company  and  furnished  to the SEC or its staff upon
request.





/s/ Charles T. Saldarini
- ------------------------

Charles T. Saldarini
Vice Chairman and Chief Executive Officer
March 14, 2005