EXHIBIT 10.8

                       ASSIGNMENT AND ASSUMPTION AGREEMENT


        THIS  ASSIGNMENT AND ASSUMPTION  AGREEMENT  ("Agreement")  is made as of
this 6th day of April 2005 by and among  LIGHTEN UP  ENTERPRISES  INTERNATIONAL,
INC., a Nevada corporation  ("Assignee"),  BIONOVO, INC., a Delaware corporation
("Assignor"), and Isaac Cohen ("Executive").

                                    RECITALS:

        A.      Assignee and Executive have entered into that certain Employment
Agreement as of July 1, 2004 ("Employment Agreement");

        B.      Assignor,  Assignee and LTUP  Acquisition  Corp., a wholly-owned
subsidiary  of  Assignee  ("Acquisition  Corp."),  are  parties to that  certain
Agreement  of Merger  and Plan of  Reorganization  dated of even  date  herewith
("Merger  Agreement"),  pursuant to which, among other things,  LTUP Acquisition
Corp. will merge with and into Assignee (the "Merger"); and

        C.      The execution  and delivery of this  Agreement is a condition to
the closing of the Merger pursuant to the Merger Agreement.

        NOW,  THEREFORE,  in  consideration  of these  premises  and the  mutual
promises  and  covenants  hereinafter  set forth and of other good and  valuable
consideration, the receipt and sufficiency of which are hereby acknowledged, the
parties agree as follows:

        1.      ASSIGNMENT AND  ASSUMPTION.  Assignor  hereby assigns all of its
rights and obligations  under the Employment  Agreement to Assignee and Assignee
hereby agrees to assume all such rights and obligations.

        2.      CONSENT.  Executive hereby consents to the within assignment and
assumption.

        3.      GENERAL.  This  Agreement  may  be  executed  and  delivered  in
counterparts  and by facsimile  machine,  each of which shall be deemed to be an
original but all of which together shall constitute one and the same instrument.
This  Agreement  shall be  governed  by and  construed  in  accordance  with the
domestic  laws of  California  without  giving  effect  to any  choice of law or
conflicting   law  provision  or  rule  (whether  of  California  or  any  other
jurisdiction)  that would cause the application of the laws of any  jurisdiction
other than  California.  The recitals  hereto are a material part hereof and are
incorporated  in this  Agreement by reference as if fully set forth  herein.  No
change or  modification  of this Agreement  shall be valid unless the same is in
writing and is signed by both parties.  In the event that any of the  provisions
of this Agreement shall be held by a court of law or other tribunal of competent
jurisdiction to be illegal,  invalid or unenforceable,  the remaining provisions
shall remain in full force and effect,  and to this end the  provisions  of this
Agreement  are  declared  to  be  severable.   Captions  and  headings  are  for
convenience  only,  are not deemed to be part of this Agreement and shall not be
used in the interpretation of this Agreement.




        IN  WITNESS  WHEREOF,  the  parties  have  caused  this  Assignment  and
Assumption  Agreement  to be  executed  as of the day and year first set for the
above.


                                    ASSIGNEE:

                                    LIGHTEN UP ENTERPRISES INTERNATIONAL, INC.

                                    By:
                                       -----------------------------------------
                                    Name:
                                         ---------------------------------------
                                    Title:
                                          --------------------------------------


                                    ASSIGNOR:

                                    BIONOVO, INC.

                                    By:
                                       -----------------------------------------
                                    Name:
                                         ---------------------------------------
                                    Title:
                                          --------------------------------------


                                    EXECUTIVE:



                                    --------------------------------------------
                                    Isaac Cohen