EXHIBIT 32 (b)

                             CERTIFICATE PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

         In  connection  with the  Annual  Report  of Enzo  Biochem,  Inc.,  and
Subsidiaries  ("the  Company")  on Form 10-K for the fiscal  year ended July 31,
2005 as filed with the  Securities  and Exchange  Commission  on the date hereof
(the  "Report"),  I, Barry  Weiner.,  Chief  Financial  Officer of the  Company,
certify,  pursuant to 18 U.S.C.  ss. 1350, as adopted pursuant to ss. 906 of the
Sarbanes-Oxley Act of 2002, that:

               (1)  The Report fully complies with the  requirements  of Section
13 (a) or 15 (d) of the Securities Exchange Act of 1934; and


               (2)  The information  contained in the Report fairly presents, in
all material respects,  the financial condition and results of operations of the
Company.



Date:  October 14, 2005                         By: /s/ Barry Weiner
                                                    ----------------

                                                        Barry Weiner
                                                        Chief Financial Officer





         A signed original of this written statement required by Section 906, or
other  document  authenticating,   acknowledging,   or  otherwise  adopting  the
signature  that  appears in typed form  within  the  electronic  version of this
written statement  required by Section 906, has been provided to the Company and
will be retained by the Company and furnished to the Securities and Exchange Act
Commission or its staff upon request.