UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

          ------------------------------------------------------------

                                   FORM 8-K/A
                                (Amendment No. 5)

                                 CURRENT REPORT

     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

       -------------------------------------------------------------------

         Date of Report (Date of earliest event reported): April 6, 2005

                                  BIONOVO, INC.
                   ------------------------------------------
               (Exact Name of Registrant as Specified in Charter)


          DELAWARE                       000-50073               87-0576481
- ----------------------------     ------------------------    -------------------
(State or other jurisdiction     (Commission File Number)       (IRS Employer
      of incorporation)                                      Identification No.)


                5858 Horton Street, Suite 375
                   Emeryville, California                     94608
                -----------------------------               ----------
          (Address of principal executive offices)          (Zip Code)


       Registrant's telephone number, including area code: (510) 601-2000


                   LIGHTEN UP ENTERPRISES INTERNATIONAL, INC.
                         2200 Powell Street, Suite 675
                          Emeryville, California 94608
                   ------------------------------------------
          (Former name or former address, if changed since last report)


================================================================================


Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions:

[ ] Written communications pursuant to Rule 425 under the Securities Act (17 CFR
    230.425)

[ ] Soliciting  material  pursuant to Rule 14a-12 under the Exchange Act (17 DFR
    240.14a-12)

[ ] Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange
    Act (17 CFR 240.14d-2(b))

[ ] Pre-commencement  communications  pursuant  to  Rule  13e-4  (c)  under  the
    Exchange Act (17 CFR 240.13e-4(c))



                          CURRENT REPORT ON FORM 8-K/A
                                (AMENDMENT NO. 5)

                                  BIONOVO, INC.


                                EXPLANATORY NOTE:

         This  Amendment  No. 5 on Form 8-K/A amends the Current  Report on Form
8-K/A,  Amendment  No. 4, dated  April 6, 2005,  of  Bionovo,  Inc.,  a Delaware
corporation  (formerly  Lighten Up  Enterprises  International,  Inc.,  a Nevada
Corporation)  ("Registrant"),  filed with the Securities and Exchange Commission
("SEC") on September 15, 2005,  which amended the Current  Report on Form 8-K/A,
Amendment  No. 3, dated April 6, 2005, of the  Registrant  filed with the SEC on
June 27, 2005, which amended the Current Report on Form 8-K/A,  Amendment No. 2,
dated  April 6, 2005,  of the  Registrant  filed with the SEC on June 22,  2005,
which amended the Current Report on Form 8-K/A,  Amendment No. 1, dated April 6,
2005, of the  Registrant  filed with the SEC on June 3, 2005,  which amended the
Current Report on Form 8-K dated April 6, 2005 of the Registrant  filed with the
SEC on  April 8,  2005.  This  Amendment  No. 5 is  being  filed  to  re-file  a
previously identified material contract under Item 9.01(c). There are no changes
to the financial information included in Items 9.01(a) and (b).

ITEM 9.01.    FINANCIAL STATEMENTS AND EXHIBITS

         (a)      FINANCIAL  STATEMENTS  OF BUSINESSES  ACQUIRED.  In accordance
with Item  9.01(a),  attached  hereto are the audited  financial  statements  of
Bionovo Biopharmaceuticals, Inc.  (formerly  Bionovo, Inc.) for the fiscal years
ended December 31, 2004 and 2003.

         (b)      PRO  FORMA  FINANCIAL  INFORMATION.  In  accordance  with Item
9.01(b),  attached  hereto  are  the  pro forma  financial statements of Bionovo
Biopharmaceuticals, Inc. (formerly Bionovo, Inc.)

         (c)      EXHIBITS.

         The exhibits listed in the following Exhibit Index are filed as part of
this Report.

    EXHIBIT NO.                           DESCRIPTION
    -----------                           -----------

       2.1        Agreement  of Merger and Plan of  Reorganization,  dated as of
                  April 6, 2005,  among  Lighten Up  Enterprises  International,
                  Inc., LTUP Acquisition Corp. and Bionovo,  Inc.  (incorporated
                  herein by reference from Exhibit 2.1 to the Registrant's  Form
                  8-K filed with the SEC on April 8, 2005)

       3.1(i)     Articles  of  Incorporation  of the  Registrant  (incorporated
                  herein by reference  from Exhibit  3.1(i) to the  Registrant's
                  Form 10-SB filed with the SEC on November 7, 2002)

       3.1(ii)    Restated  and  Amended   Articles  of   Incorporation  of  the
                  Registrant  (incorporated  herein by  reference  from  Exhibit
                  3.1(ii) to the  Registrant's  Form 10-SB filed with the SEC on
                  November 7, 2002)

       3.1(iii)   Certificate  of Amendment to Restated and Amended  Articles of
                  Incorporation  of  the  Registrant   (incorporated  herein  by
                  reference from Exhibit 3.1(iii) to the Registrant's Form 10-SB
                  filed with the SEC on November 7, 2002)

       3.2        By-laws of the  Registrant  (incorporated  herein by reference
                  from Exhibit 3.2 to the Registrant's Form 10-SB filed with the
                  SEC on November 7, 2002)

       4.1        Form of  Private  Placement  Warrant  (incorporated  herein by
                  reference from Exhibit 4.1 to the Registrant's  Form 8-K filed
                  with the SEC on May 11, 2005)



      10.1        Form of Private Placement Subscription Agreement (incorporated
                  herein by reference from Exhibit 10.1 to the Registrant's Form
                  8-K filed with the SEC on May 11, 2005)

      10.2        Form of Private Placement Investor Questionnaire (incorporated
                  herein by reference from Exhibit 10.2 to the Registrant's Form
                  8-K filed with the SEC on May 11, 2005)

      10.3        Form  of  Private  Placement   Registration  Rights  Agreement
                  (incorporated  herein by  reference  from  Exhibit 10.3 to the
                  Registrant's Form 8-K filed with the SEC on May 11, 2005)

      10.4        Form  of  Private  Placement   Acknowledgement  and  Amendment
                  (incorporated  herein by  reference  from  Exhibit 10.4 to the
                  Registrant's Form 8-K filed with the SEC on May 11, 2005)

      10.5        Registration  Rights  Agreement,   dated  September  30,  2004
                  (incorporated  herein by  reference  from  Exhibit 10.5 to the
                  Registrant's  Form 8-K/A,  Amendment No. 1, filed with the SEC
                  on June 3, 2005)

      10.6        Stock  Incentive  Plan,  as  amended  (incorporated  herein by
                  reference  from  Exhibit 5 to the  Registrant's  Schedule  14C
                  filed with the SEC on June 3, 2005)

      10.7        Employment  Agreement,  dated July 1, 2004,  between  Bionovo,
                  Inc. and Isaac Cohen  (incorporated  herein by reference  from
                  Exhibit 10.7 to the Registrant's Form 8-K/A,  Amendment No. 1,
                  filed with the SEC on June 3, 2005)

      10.8        Assignment  and  Assumption  Agreement,  dated  April 6, 2005,
                  among  Registrant,  Bionovo,  Inc.  and Isaac Cohen  regarding
                  Employment  Agreement  (incorporated  herein by reference from
                  Exhibit 10.8 to the Registrant's Form 8-K/A,  Amendment No. 1,
                  filed with the SEC on June 3, 2005)

      10.9        Employment  Agreement,  dated July 1, 2004,  between  Bionovo,
                  Inc. and Mary  Tagliaferri  (incorporated  herein by reference
                  from Exhibit 10.9 to the  Registrant's  Form 8-K/A,  Amendment
                  No. 1, filed with the SEC on June 3, 2005)

      10.10       Assignment  and  Assumption  Agreement,  dated  April 6, 2005,
                  among  the  Registrant,  Bionovo,  Inc.  and Mary  Tagliaferri
                  regarding   Employment   Agreement   (incorporated  herein  by
                  reference from Exhibit 10.10 to the  Registrant's  Form 8-K/A,
                  Amendment No. 1, filed with the SEC on June 3, 2005)

      10.11       Licensing &  Technology Transfer Agreement,  dated November 6,
                  2003, with United Biotech  Corporation (certain  terms of this
                  agreement  have been  omitted and are subject to a request for
                  confidential  treatment with the SEC)

      21.1        Subsidiaries of Registrant (previously filed)



                                   SIGNATURES

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  Registrant  has duly  caused  this report to be signed on its behalf by the
undersigned thereunto duly authorized.


Date:  October 19, 2005               LIGHTEN UP ENTERPRISES INTERNATIONAL, INC.


                                      By: /s/ James P. Stapleton
                                          ---------------------------------
                                           James P. Stapleton
                                           Chief Financial Officer



BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
TABLE OF CONTENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------



                                                                    PAGE
                                                                    ----
REPORT OF INDEPENDENT REGISTERED
  PUBLIC ACCOUNTING FIRM                                             1

FINANCIAL STATEMENTS:
  Balance Sheets                                                     2
  Statements of Operations                                           3
  Statements of Stockholders' Deficit                                4
  Statements of Cash Flows                                           5
  Notes to Financial Statements                                     6-20



             REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM



Board of Directors
BioNovo Biopharmaceuticals, Inc. (formerly BioNovo, Inc.)
Emeryville, California

We have audited the accompanying  balance sheets of BioNovo  Biopharmaceuticals,
Inc. (formerly  BioNovo,  Inc.) (a Development Stage Company) as of December 31,
2004 and 2003, and the related statements of operations,  stockholders' deficit,
and cash flows for the years then ended and from  inception,  February  1, 2002,
through December 31, 2004. These financial  statements are the responsibility of
the Company's  management.  Our responsibility is to express an opinion on these
financial statements based on our audits.

We conducted our audits in accordance  with the standards of the Public  Company
Accounting Oversight Board (United States). Those standards require that we plan
and  perform  the  audits to  obtain  reasonable  assurance  about  whether  the
financial  statements  are free of  material  misstatement.  An  audit  includes
examining,  on a test basis,  evidence supporting the amounts and disclosures in
the  financial  statements.  An audit also  includes  assessing  the  accounting
principles  used  and  significant  estimates  made  by  management,  as well as
evaluating the overall  financial  statement  presentation.  We believe that our
audits provide a reasonable basis for our opinion.

In our opinion,  the financial  statements  referred to above present fairly, in
all material  respects,  the financial  position of BioNovo  Biopharmaceuticals,
Inc.  (formerly  BioNovo,  Inc.) as of  December  31,  2004 and  2003,  and from
inception,  February 1, 2002,  through December 31, 2004, and the results of its
operations  and its cash  flows  for the years  then  ended in  conformity  with
accounting principles generally accepted in the United States of America.


/s/ Stonefield Josephson, Inc.

CERTIFIED PUBLIC ACCOUNTANTS

San Francisco, California
April 8, 2005, except for paragraph 6 of Note 12 which its date is June 28, 2005



BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
BALANCE SHEETS
- --------------------------------------------------------------------------------

                                                    December 31,    December 31,
                                                        2004            2003
                                                    ------------    ------------
ASSETS

CURRENT ASSETS:
  Cash and cash equivalents                           $ 196,013       $  73,867
  Due from officers                                       1,796              --
  Prepaid expenses and other current assets                  --          15,156
                                                      ---------       ---------

         Total current assets                           197,809          89,023

PROPERTY AND EQUIPMENT,
  net of accumulated depreciation                         9,859           2,795

OTHER ASSETS:
  Deferred loan costs
     net of accumulated amortization                     65,551              --
  Patent pending costs                                   11,264              --
                                                      ---------       ---------

                                                      $ 284,483       $  91,818
                                                      =========       =========

LIABILITIES AND STOCKHOLDERS' DEFICIT

CURRENT LIABILITIES:
  Accounts payable and accrued expenses               $ 163,613       $      --
  Accrued pension payable                                52,000              --
  Deferred revenue                                       15,000          15,000
  Convertible notes payable                             500,000              --
                                                      ---------       ---------

         Total current liabilities                      730,613          15,000
                                                      ---------       ---------

DEFERRED REVENUE                                        117,500         132,500
                                                      ---------       ---------

STOCKHOLDERS' DEFICIT:
  Common stock, $0.001 par value:
     Authorized shares - 24,400,000 issued
      and outstanding common shares - 24,400,000
                                                         24,400          24,400
  Additional paid-in capital                              5,600         (24,400)
  Accumulated deficit                                  (593,630)        (55,682)
                                                      ---------       ---------

          Total stockholders' deficit                  (563,630)        (55,682)
                                                      ---------       ---------

                                                      $ 284,483       $  91,818
                                                      =========       =========



The accompanying notes form an integral part of these financial statements.    2


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
STATEMENTS OF OPERATIONS
- --------------------------------------------------------------------------------



                                                                                            Accumulated from
                                                   Year Ended            Year Ended         February 1, 2002
                                                  December 31,          December 31,     (Date of Inception) to
                                                      2004                  2003            December 31, 2004
                                                  ------------          ------------     ----------------------

                                                                                     
REVENUE                                           $     45,240          $      2,500          $     47,740
                                                  ------------          ------------          ------------

OPERATING EXPENSES:
  Research and development                             275,600                22,179               297,779
  General and administrative                           277,433                35,203               312,636
  Sales and marketing                                      500                    --                   500
                                                  ------------          ------------          ------------

         Total operating expenses                      553,533                57,382               610,915
                                                  ------------          ------------          ------------

LOSS FROM OPERATIONS                                  (508,293)              (54,882)             (563,175)

OTHER INCOME (EXPENSE):
  Interest expense, net of $495
  in 2004, and $0 in 2003 of
  interest income                                      (28,855)                   --               (28,855)
                                                  ------------          ------------          ------------

LOSS BEFORE INCOME
 TAXES                                                (537,148)              (54,882)             (592,030)

PROVISION FOR INCOME TAXES                                (800)                 (800)               (1,600)
                                                  ------------          ------------          ------------

NET LOSS                                          $   (537,948)         $    (55,682)         $   (593,630)
                                                  ============          ============          ============

NET LOSS PER SHARE                                $      (0.02)         $      (0.00)         $      (0.02)
                                                  ============          ============          ============

WEIGHTED AVERAGE SHARES OUTSTANDING                 24,400,000            24,400,000            24,400,000
                                                  ============          ============          ============




The accompanying notes form an integral part of these financial statements.    3


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
STATEMENTS OF STOCKHOLDERS' DEFICIT
INCEPTION THROUGH DECEMBER 31, 2004
- --------------------------------------------------------------------------------



                                                Common Stock                                 Accumulated
                                       ----------------------------        Additional       Deficit During
                                        Number of                           Paid-In          Development
                                         Shares            Amount           Capital             Stage              Total
                                       ----------        ----------        ----------         ----------         ----------

                                                                                                  
BALANCE AT INCEPTION
  (February 1, 2002)-Adjusted to
  reflect effect of stock split
  on June 17, 2004 and reverse
  merger on April 6, 2005              24,400,000        $    2,440        $   (2,440)        $       --         $       --
                                       ----------        ----------        ----------         ----------         ----------

BALANCE, December 31, 2002             24,400,000             2,440            (2,440)                --                 --

NET LOSS                                                                                         (55,682)           (55,682)
                                       ----------        ----------        ----------         ----------         ----------

BALANCE, December 31, 2003             24,400,000             2,440            (2,440)           (55,682)           (55,682)

NONCASH COMPENSATION
  EXPENSE FOR OPTIONS ISSUED                   --                --            30,000                 --             30,000

NET LOSS                                                                                        (537,948)          (537,948)
                                       ----------        ----------        ----------         ----------         ----------

BALANCE, December 31, 2004             24,400,000        $    2,440        $   27,560         $ (593,630)        $ (563,630)
                                       ==========        ==========        ==========         ==========         ==========




The accompanying notes form an integral part of these financial statements.    4


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
STATEMENTS OF CASH FLOWS
- --------------------------------------------------------------------------------



                                                                                                       Accumulated from
                                                                   Year Ended         Year Ended       February 1, 2002
                                                                  December 31,       December 31,   (Date of Inception) to
                                                                      2004               2003         December 31, 2004
                                                                  ------------       ------------   ----------------------

                                                                                                 
CASH FLOWS PROVIDED BY (USED FOR) OPERATING
 ACTIVITIES:

 Net loss                                                           $(537,948)         $ (55,682)         $(593,630)
                                                                    ---------          ---------          ---------

 ADJUSTMENTS TO RECONCILE NET LOSS
  TO NET CASH PROVIDED BY (USED FOR)
  OPERATING ACTIVITIES:
    Depreciation                                                        1,821              3,090              4,911
    Amortization of note discount                                      21,850                 --             21,850
    Noncash compensation expense for options issued                    30,000                                30,000

 CHANGES IN ASSETS AND LIABILITIES:
  (INCREASE) DECREASE IN ASSETS:
    Prepaid expenses                                                   15,156            (15,156)                --

  INCREASE (DECREASE) IN LIABILITIES:
    Accounts payable and accrued expenses                             163,613                 --            163,613
    Deferred tax liability                                            (15,000)           147,500            132,500
    Accrued pension payable                                            52,000                 --             52,000
                                                                    ---------          ---------          ---------

    Total adjustments                                                 269,440            135,434            404,874
                                                                    ---------          ---------          ---------

    Net cash provided by (used for) operating activities             (268,508)            79,752           (188,756)
                                                                    ---------          ---------          ---------

CASH FLOWS USED FOR INVESTING ACTIVITIES:
  Acquisition of intangible assets                                    (11,264)                --            (11,264)
  Acquisition of fixed assets                                          (8,885)            (5,885)           (14,770)
  Advance to officers                                                  (1,796)                --             (1,796)
                                                                    ---------          ---------          ---------

    Net cash used for investing activities                            (21,945)            (5,885)           (27,830)
                                                                    ---------          ---------          ---------

CASH FLOWS PROVIDED BY FINANCING ACTIVITIES:
  Proceeds from convertible notes payable                             500,000                 --            500,000
  Payments for financing costs for convertible notes                  (87,401)                --            (87,401)
                                                                    ---------          ---------          ---------

    Net cash provided by financing activities                         412,599                 --            412,599
                                                                    ---------          ---------          ---------

NET INCREASE IN CASH                                                  122,146             73,867            196,013

CASH, beginning of year                                                73,867                 --                 --
                                                                    ---------          ---------          ---------

CASH, end of year                                                   $ 196,013          $  73,867          $ 196,013
                                                                    =========          =========          =========

SUPPLEMENTAL DISCLOSURE OF CASH FLOW
 INFORMATION:

  Interest paid                                                     $      --          $      --          $      --
                                                                    =========          =========          =========

  Income taxes paid                                                 $     800          $     800          $   1,600
                                                                    =========          =========          =========

SUPPLEMENTAL DISCLOSURE OF NONCASH INVESTING
 INVESTING ACTIVITIES-
    Noncash compensation expense for options issued                 $  30,000          $      --          $  30,000
                                                                    =========          =========          =========




The accompanying notes form an integral part of these financial statements.    5


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
NOTES TO FINANCIAL STATEMENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------

(1)      BUSINESS AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES:

         FORMATION AND BUSINESS OF THE COMPANY:

                  BioNovo,  Inc., (the "Company") was incorporated in California
                  on February 2, 2002. A new company was formed and incorporated
                  in Delaware on March 3, 2004, and was merged and recapitalized
                  with the California corporation.

                  The  Company  is a  drug  discovery  and  development  company
                  focusing on cancer and women's health,  primarily using select
                  plant extracts to screen against well  understood  therapeutic
                  targets. The Company has a unique  developmental  pathway that
                  leverages   understanding   of  modern  drug   discovery  with
                  experience in clinical development.

         DEVELOPMENT STAGE COMPANY:

                  The Company has not  generated any  significant  revenue since
                  inception.   The   accompanying   financial   statement   has,
                  therefore,   been  prepared  using  the   accounting   formats
                  prescribed for a development stage enterprise (DSE).  Although
                  the Company has  recognized  some  revenue,  the Company still
                  believes it is devoting  substantial efforts on developing the
                  business and, therefore, still qualifies as a DSE.

         USE OF ESTIMATES:

                  The  preparation  of financial  statements in conformity  with
                  accounting  principles generally accepted in the United States
                  of  America   requires   management  to  make   estimates  and
                  assumptions   that  affect  the   amounts  in  the   financial
                  statements and accompanying notes. Actual results could differ
                  from those estimates.

         FAIR VALUE OF FINANCIAL INSTRUMENTS:

                  The carrying amount of cash equivalents,  accounts receivable,
                  accounts payable,  and notes payable  approximates  their fair
                  value  either  due to the  short  duration  to  maturity  or a
                  comparison to market interest rates for similar instruments.

         CASH:

                  CASH EQUIVALENTS

                  The Company considers all highly liquid investments  purchased
                  with an original  maturity of three months or less at the time
                  of purchase to be cash equivalents.  The Company maintains the
                  majority of its cash and cash equivalents at two major banks.

                  CASH CONCENTRATION

                  The  Company  maintains  its cash in bank  accounts,  which at
                  times may exceed federally insured limits. The Company has not
                  experienced any losses on such accounts.

                                                                               6


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
NOTES TO FINANCIAL STATEMENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------

(1)      BUSINESS AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED):

         PROPERTY AND EQUIPMENT:

                  Fixed assets are stated at cost less accumulated depreciation.
                  Depreciation is calculated using the straight-line method over
                  the  estimated  useful  lives of the assets,  which  generally
                  range from three to five years.

         IMPAIRMENT OF LONG-LIVED ASSETS:

                  The Company  assesses the impairment of its long-lived  assets
                  periodically in accordance with the provisions of Statement of
                  Financial  Accounting  Standards ("SFAS") 144, "Accounting for
                  the  Impairment and Disposal of Long-Lived  Assets".  Whenever
                  events or changes in circumstances  indicate that the carrying
                  amounts  of  long-lived  assets  may not be  recoverable,  the
                  Company will compare  undiscounted net cash flows estimated to
                  be generated  by those assets to the carrying  amount of those
                  assets.  When these  undiscounted cash flows are less than the
                  carrying  amounts  of the  assets,  the  Company  will  record
                  impairment  losses  to write  the  asset  down to fair  value,
                  measured  by the  discounted  estimated  net future cash flows
                  expected to be  generated  from the assets.  To date there has
                  been no impairment.

         DEFERRED LOAN COSTS:

                  Deferred  loan  costs  relate to the direct  costs  related to
                  obtaining debt financing for the Company and will be amortized
                  over the life of the debt using the effective  interest method
                  of accounting.

         PATENT PENDING COSTS:

                  Intangible  assets consist of patent  licensing costs to date.
                  If the patents are awarded,  the costs will be amortized  over
                  the term of the patents.  If the patents are not awarded,  the
                  costs  related to those patents will be expensed in the period
                  that determination is made.

         INCOME TAXES:

                  Deferred income taxes are recognized for the tax  consequences
                  in future years of differences between the tax basis of assets
                  and liabilities and their financial  reporting amounts at each
                  year end based on  enacted  tax laws and  statutory  tax rates
                  applicable  to  the  periods  in  which  the  differences  are
                  expected to affect taxable  income.  Valuation  allowances are
                  established,  when necessary, to reduce deferred tax assets to
                  the amount expected to be realized.

         DEFERRED REVENUE:

                  Deferred   revenue  consists  of  upfront  fees  received  for
                  technology  licensing  that  have not yet been  recognized  or
                  earned.

                                                                               7


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
NOTES TO FINANCIAL STATEMENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------

(1)      BUSINESS AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED):

         CONVERTIBLE NOTES PAYABLE:

                  In January 2001,  the  Financial  Accounting  Standards  Board
                  Emerging  Issues Task Force  issued EITF 00-27  effective  for
                  convertible debt  instruments  issued after November 16, 2000.
                  This  pronouncement  requires the use of the  intrinsic  value
                  method for  recognition of the detachable and imbedded  equity
                  features included with indebtedness and requires  amortization
                  of the amount associated with the convertibility  feature over
                  the life of the debt  instrument  rather  than the  period for
                  which the instrument becomes convertible.

         STOCK-BASED COMPENSATION:

                  The  Company   accounts  for   stock-based   compensation   in
                  accordance  with Accounting  Principles  Board ("APB") Opinion
                  No.  25,  "Accounting  for  Stock  Issued to  Employees",  and
                  complies  with the  disclosure  provisions  of SFAS  No.  123,
                  "Accounting for Stock-Based  Compensation".  Under APB No. 25,
                  compensation  cost is recognized over the vesting period based
                  on the  excess,  if any,  on the date of  grant of the  market
                  value of the  Company's  shares over the  employee's  exercise
                  price.  When the exercise price of the option is less than the
                  fair value price of the  underlying  shares on the grant date,
                  deferred  stock  compensation  is recognized  and amortized to
                  expense in  accordance  with  Financial  Accounting  Standards
                  Board ("FASB")  Interpretation  No. 44 over the vesting period
                  of the individual options.

                  Accordingly,  if the exercise price of the Company's  employee
                  options  equals or exceeds the market price of the  underlying
                  shares  on the  date of  grant,  no  compensation  expense  is
                  recognized.  Options or shares awards  issued to  nonemployees
                  are valued using the Black-Scholes  pricing model and expensed
                  over the period services are provided.

                  In December  2002,  the FASB issued SFAS No. 148,  "Accounting
                  for  Stock-Based  Compensation - Transition  and  Disclosure",
                  which  amends  SFAS  No.  123,   "Accounting  for  Stock-Based
                  Compensation",  to provide  alternative  methods of transition
                  for a  voluntary  change  to the fair  value-based  method  of
                  accounting for stock-based employee compensation. In addition,
                  SFAS No. 148 expands the disclosure  requirements  of SFAS No.
                  123 to require more  prominent  disclosures in both annual and
                  interim  financial  statements  about the method of accounting
                  for stock-based  employee  compensation  and the effect of the
                  method used on reported results. The transition  provisions of
                  SFAS No.  148 are  effective  for  fiscal  years  ended  after
                  December 15, 2002. The transition  provisions do not currently
                  have an impact on the Company's financial position and results
                  of operations as the Company has not elected to adopt the fair
                  value-based  method of  accounting  for  stock-based  employee
                  compensation under SFAS NO. 123. The disclosure  provisions of
                  SFAS  No.  148 are  effective  for  financial  statements  for
                  interim periods beginning after December 15, 2002. The Company
                  adopted the  disclosure  requirements  in the first quarter of
                  fiscal year 2003.

                                                                               8


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
NOTES TO FINANCIAL STATEMENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------

(1)      BUSINESS AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED):

         STOCK-BASED COMPENSATION (CONTINUED):

                  The  following  table  illustrates  the effect on net loss and
                  loss per  share if the  Company  had  applied  the fair  value
                  recognition  provisions of FASB Statement No. 123,  Accounting
                  for   Stock-Based   Compensation,   to  Stock-Based   Employee
                  Compensation.



                                                                Years Ended December 31,
                                                               -------------------------
                                                                 2004            2003
                                                               ---------       ---------

                                                                         
                  Net income (loss) available as reported      $(537,948)      $ (54,882)
                  Compensation recognized under APB 25            30,000              --
                  Compensation recognized under SFAS 123        (100,000)             --
                                                               ---------       ---------

                  Pro-forma net income (loss) available        $(607,948)      $ (54,882)
                                                               =========       =========
                  Loss per share, as reported                  $  (0.026)      $  (0.003)
                                                               =========       =========
                  Loss per share, pro-forma                    $  (0.030)      $  (0.003)
                                                               =========       =========


                  For grants in 2004, the following  assumptions  were used: (i)
                  no expected dividends;  (ii) a risk-free interest rate ranging
                  from 3.5% to 5.5%  during the year ended  December  31,  2004,
                  (iii) expected  volatility  0.0%, and (iv) an expected life of
                  the stated life of the option for options granted in 2004. The
                  fair   value   was   determined   using   the    Black-Scholes
                  option-pricing model.

                  The  estimated  fair  value of  grants  of stock  options  and
                  warrants to nonemployees of the Company is charged to expense,
                  if applicable, in the financial statements. These options vest
                  in the same manner as the employee  options granted under each
                  of the option plans as described above.

         REVENUE RECOGNITION:

                  Revenue  is   generated   from   collaborative   research  and
                  development arrangements,  technology licenses, and government
                  grants. To date only revenue from technology licenses has been
                  received.

                  Revenue is recognized  when the four basic criteria of revenue
                  recognition are met: (i) a contractual  agreement exists; (ii)
                  transfer of  technology  has been  completed or services  have
                  been  rendered;  (iii) the fee is fixed or  determinable,  and
                  (iv) collectibility is reasonably assured.

                  Technology  license agreements are for a term of ten years and
                  consist of  nonrefundable  upfront  license  fees and  royalty
                  payments.  In accordance with Staff  Accounting  Bulletin 104,
                  nonrefundable  upfront  license fees are  recognized  over the
                  license term using the straight-line method of accounting when
                  the technology is  transferred or accessed,  provided that the
                  technology  transferred  or accessed is not  dependent  on the
                  outcome of the Company's  continuing  research and development
                  efforts.

                                                                               9


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
NOTES TO FINANCIAL STATEMENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------

(1)      BUSINESS AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED):

         RESEARCH AND DEVELOPMENT:

                  Research  and  development   expenses   include  internal  and
                  external costs. Internal costs include salaries and employment
                  related  expenses  and  allocated  facility  costs.   External
                  expenses consist of costs associated with outsourced  clinical
                  research organization activities,  sponsored research studies,
                  product  registration,  and investigator  sponsored trials. In
                  accordance   with  SFAS  No.  2,   "ACCOUNTING   FOR  RESEARCH
                  DEVELOPMENT  COSTS",  all such costs are charged to expense as
                  incurred.

(2)      RECENT ACCOUNTING PRONOUNCEMENTS:

         In December 2004,  the Financial  Accounting  standards  Board ("FASB")
         issued  SFAS  No.  123(R),   "Share-Based  Payment".  SFAS  No.  123(R)
         addresses accounting for share-based  payments to employees,  including
         grants of employee  stock  options.  Under the new standard,  companies
         will  no  longer  be  able  to  account  for  share-based  compensation
         transactions  using the intrinsic  method in accordance with Accounting
         Principles  Board ("APB") Opinion No. 25,  "Accounting for Stock Issued
         to Employees".  Instead, companies will be required to account for such
         transactions using a fair-value method and recognize the expense in the
         statement  of income.  SFAS No.  123(R) will be  effective  for periods
         beginning  after  June 15,  2005,  and  allows,  but does not  require,
         companies to restate the full fiscal year of 2005 to reflect the impact
         of expensing share-based payment under SFAS No. 123(R). The Company has
         not yet determined which fair-value  method and transitional  provision
         it will  follow.  However,  it expects  that the  adoption  of SFAS No.
         123(R) will have a significant impact on its results of operations. The
         Company does not expect the adoption of SFAS No. 123(R) will impact its
         overall financial  position.  There was no impact on net income and net
         income per share from calculating stock-based  compensation costs under
         the fair value alternative of SFAS No. 123. However, the calculation of
         compensation  cost  for  share-based  payment  transactions  after  the
         effective date of SFAS 123(R) will be different from the calculation of
         compensation cost under SFAS No. 123, but such differences have not yet
         been quantified.

         In December  2004, the FASB issued SFAS No. 152,  "Accounting  for Real
         Estate Time-Sharing  Transactions - an Amendment of FASB Statements No.
         66 and 67" ("SFAS No. 152").  This Statement  amends FASB Statement No.
         66,  "Accounting for Sales of Real Estate",  to reference the financial
         accounting  and  reporting   guidance  for  real  estate   time-sharing
         transactions  that is provided  in AICPA  Statement  of Position  (SOP)
         04-2,  "Accounting  for Real Estate  Time-Sharing  Transactions".  This
         Statement also amends FASB Statement No. 67,  "Accounting for Costs and
         Initial Rental Operations of Real Estate  Projects",  to state that the
         guidance for (a)  incidental  operations and (b) costs incurred to sell
         real  estate  projects  do  not  apply  to  real  estate   time-sharing
         transactions.  The accounting for those operations and costs is subject
         to the guidance in SOP 04-2.  This Statement is effective for financial
         statements for fiscal years beginning after June 15, 2005, with earlier
         application  encouraged.  The Company has  evaluated  the impact of the
         adoption  of SFAS No.  152 and  does not  believe  the  impact  will be
         significant to the Company's overall results of operations or financial
         position,   as  the   Company   does  not  engage  in  these  sorts  of
         transactions.

                                                                              10


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
NOTES TO FINANCIAL STATEMENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------

(2)      RECENT ACCOUNTING PRONOUNCEMENTS (CONTINUED):

         In  December  2004,  the  FASB  issued  SFAS  No.  153,  "Exchanges  of
         Nonmonetary Assets", an amendment of AOB Opinion No. 29. This statement
         was the  result  of a joint  effort  by the FASB and the  International
         Accounting  Standards Board ("IASB") to improve financial  reporting by
         eliminating   certain   narrow   differences   between  their  existing
         standards.  One such  difference  was the  exception  from  fair  value
         measurement  in  AOB  Opinion  No.  29,   "Accounting  for  Nonmonetary
         Transactions",  for nonmonetary exchanges of similar productive assets.
         SFAS No. 153 replaces this exception with a general exception from fair
         value measurement for exchanges of nonmonetary  assets that do not have
         commercial  substance.  A nonmonetary exchange has commercial substance
         if the  future  cash  flows  of  the  entity  are  expected  to  change
         significantly  as a result of the  exchange.  This  statement  shall be
         applied  prospectively and is effective for nonmonetary asset exchanges
         occurring in fiscal periods  beginning after June 15, 2005. The Company
         does not believe that the adoption of SFAS No. 153 will have a material
         effect on its financial statements.

         In November 2004, the FASB issued SFAS No. 151,  "Inventory  Costs - an
         Amendment of ARB No. 42, Chapter 4". The  amendments  made by Statement
         No.  151  clarify  that  abnormal  amounts  of idle  facility  expense,
         freight,  handling costs,  and wasted  materials  (spoilage)  should be
         recognized  as  current-period  charges and require the  allocation  of
         fixed production overheads to inventory based on the normal capacity of
         the  production  facilities.  The guidance is effective  for  inventory
         costs  incurred  during  fiscal  years  beginning  after June 15, 2005.
         Earlier  application is permitted for inventory  costs incurred  during
         fiscal  years  beginning  after  November  23,  2004.  The  Company has
         evaluated  the  impact  of the  adoption  of SFAS No.  151 and does not
         believe the impact will be significant to the Company's overall results
         of operations or financial position.

         In March  2004,  the  Emerging  Issues  Task Force  ("EITF")  reached a
         consensus on recognition and measurement  guidance previously discussed
         under EITF No. 03-01, "The Meaning of  Other-Than-Temporary  Impairment
         and Its Application To Certain  Investments".  The consensus  clarified
         the meaning of  other-than-temporary  impairment and its application to
         debt and equity investments  accounted for under SFAS No. 115 and other
         investments  accounted for under the cost method.  The  recognition and
         measurement  guidance for which the consensus was reached in March 2004
         is to be  applied to  other-than-temporary  impairment  evaluations  in
         reporting periods beginning after June 15, 2004. In September 2004, the
         FASB issued a final FASB Staff  Position that delays the effective date
         for the measurement and recognition guidance for all investments within
         the scope of EITF No 03-01.  The  consensus  reached in March 2004 also
         provided  for  certain  disclosure  requirements  associated  with cost
         method  investments  that were  effective for fiscal years ending after
         June 15,  2004.  The Company  will  evaluate the effect of adopting the
         recognition  and  measurement  guidance  when the  final  consensus  is
         reached.

         In December  2003,  the FASB issued  Statement of Financial  Accounting
         Standards (FAS) No. 132 (Revised 2003)  "Employers'  Disclosures  about
         Pensions and Other  Postretirement  Benefits".  This standard  replaces
         FAS-132 of the same  title,  which was  previously  issued in  February
         1998. The revised FAS-132 was issued in response to concerns  expressed
         by

                                                                              11


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
NOTES TO FINANCIAL STATEMENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------

(2)      RECENT ACCOUNTING PRONOUNCEMENTS (CONTINUED):

         financial  statement  users about their need for more  transparency  of
         pension  information.  The revised standard increases the existing GAAP
         disclosures for defined benefit pension plans and other defined benefit
         postretirement  plans.  However,  it does not change the measurement or
         recognition  of  those  plans as  required  under  FAS-87,  "Employers'
         Accounting   for   Pensions",   FAS-88,   "Employers'   Accounting  for
         Settlements  and  Curtailments of Defined Benefit Pension Plans and for
         Termination   Benefits",   and  FAS-106,   "Employers'  Accounting  for
         Postretirement Benefits Other Than Pensions". Specifically, the revised
         standard  requires  companies to provide  additional  disclosures about
         pension plan assets, benefit obligations, cash flows, and benefit costs
         of  defined   benefit   pension   plans  and  other   defined   benefit
         postretirement  plans. Also, for the first time, companies are required
         to  provide  a  breakdown  of plan  assets by  category,  such as debt,
         equity,  and real  estate,  and to provide  certain  expected  rates of
         return and target  allocation  percentages for these asset  categories.
         The revised  FAS-132 is effective for financial  statements with fiscal
         years ending after December 15, 2003, and for interim periods beginning
         after  December 15, 2003. The adoption of this Statement did not have a
         material  impact  on  the  Company's  financial  position,  results  of
         operations, or cash flows.

         In December 2003, the Securities and Exchange Commission ("SEC") issued
         Staff Accounting Bulletin ("SAB") No. 104, "Revenue  Recognition".  SAB
         No. 104  supersedes  SAB No. 101,  "Revenue  Recognition  in  Financial
         Statements".  SAB  104's  primary  purpose  is  to  rescind  accounting
         guidance  contained in SAB No. 101 related to multiple  element revenue
         arrangements,  superseded  as a result of the  issuance  of EITF 00-21,
         "Accounting  for  Revenue  Arrangements  with  Multiple  Deliverables".
         Additionally,  SAB No. 104 rescinds the SEC's  Revenue  Recognition  in
         Financial Statements Frequently Asked Questions and Answers ("the FAQ")
         issued with SAB No. 101 that had been codified in SEC Topic 13, Revenue
         Recognition.  Selected  portions of the FAQ have been incorporated into
         SAB No.  104.  While the  wording of SAB No. 104 has changed to reflect
         the issuance of EITF 00-21, the revenue  recognition  principles of SAB
         No. 101 remain largely  unchanged by the issuance of SAB No. 104, which
         was effective upon issuance. The adoption of SAB No. 104 did not impact
         the financial statements.

         In May 2003,  the FASB  issued SFAS No.  150,  "Accounting  for Certain
         Financial  Instruments  with  Characteristics  of both  Liabilities and
         Equity".   SFAS  No.  150  establishes  standards  for  how  an  issuer
         classifies   and   measures   certain   financial    instruments   with
         characteristics  of both  liabilities  and  equity.  It  requires  that
         issuers  classify a financial  instrument that is within its scope as a
         liability (or an asset in some circumstances). With certain exceptions,
         this Statement is effective for financial  instruments  entered into or
         modified  after  May  31,  2003,  and  otherwise  is  effective  at the
         beginning of the first interim  period  beginning  after June 15, 2003.
         The adoption of this  Statement  did not have a material  impact on the
         Company's financial position, results of operations, or cash flows.

         In April 2003,  the FASB issued SFAS No. 149,  "Amendment  of Statement
         133 on Derivative  Instruments  and Hedging  Activities".  SFAS No. 149
         amends and clarifies  financial  accounting and reporting of derivative
         instruments, including certain derivative instruments embedded in other
         contracts  (collectively  referred to as  derivatives)  and for hedging
         activities under SFAS No. 133,  "Accounting for Derivative  Instruments
         and Hedging  Activities".  This  Statement is effective  for  contracts
         entered  into or  modified  after June 30,  2003,  except  for  certain
         hedging

                                                                              12


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
NOTES TO FINANCIAL STATEMENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------

(2)      RECENT ACCOUNTING PRONOUNCEMENTS (CONTINUED):

         relationships  designated  after June 30,  2003.  The  adoption of this
         Statement  did not have a material  impact on the  Company's  financial
         position, results of operations, or cash flows.

         In January 2003,  the FASB issued FASB  Interpretation  No.  ("FIN") 46
         (revised December 2003 by FIN 46R),  CONSOLIDATION OF VARIABLE INTEREST
         ENTITIES,  which  addresses how a business  enterprise  should evaluate
         whether it has a controlling  financial  interest in an entity  through
         means other than voting rights and, accordingly, should consolidate the
         entity.  The  Company  will be  required  to apply FIN 46R to  variable
         interests in variable interest entities ("VIEs") created after December
         31,  2004.  For variable  interests  in VIEs that must be  consolidated
         under FIN 46R that were  created  before  January 1, 2004,  the assets,
         liabilities, and noncontrolling interests of the VIE initially would be
         measured at their carrying amounts with any difference  between the net
         amount  added  to the  balance  sheet  and  any  previously  recognized
         interest  being  recognized as the  cumulative  effect of an accounting
         change.  If determining the carrying amounts is not  practicable,  fair
         value at the date FIN 46R  first  applies  may be used to  measure  the
         assets,  liability, and noncontrolling interest of the VIE. The Company
         believes the adoption of FIN 46R will not have a material impact to its
         financial position, results of operations, or cash flows as the Company
         does not have any VIEs.

(3)      MAJOR CUSTOMERS:

         During  the year ended  December  31,  2003,  one  nonrelated  customer
         accounted  for 100% of the revenue.  There were no major  customers for
         December 31, 2004.

(4)      PROPERTY AND EQUIPMENT:

         A summary is as follows:

                                                   December 31,     December 31,
                                                       2004             2003
                                                   ------------     ------------

         Furniture and fixtures                       $14,770          $ 5,884
         Less accumulated depreciation                 (4,911)          (3,089)
                                                      -------          -------

                                                      $ 9,859          $ 2,795
                                                      =======          =======

                                                                              13


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
NOTES TO FINANCIAL STATEMENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------

(5)      DEFERRED LOAN COSTS:

         A summary is as follows:

                                                   December 31,     December 31,
                                                       2004             2003
                                                   ------------     ------------

         Loan Costs                                  $ 87,401         $     --
         Less accumulated amortization                (21,850)              --
                                                     --------         --------

                                                     $ 65,551         $     --
                                                     ========         ========


(6)      PENSION PLAN:

         During the year ended  December  31,  2004,  the  Company has adopted a
         simplified   Employee   Pension   Program  where  the  Company,   on  a
         discretionary  basis,  can  contribute  up 25% of eligible  participant
         salaries up to an annual  maximum in accordance  with IRS  regulations.
         The Company made a $ 52,000  contribution  for the year ending December
         31, 2004.

(7)      CONVERTIBLE NOTES PAYABLE:

         The Company issued  $500,000 of convertible  notes payable on September
         30,  2004.  The notes are  secured  and bear  interest at 6% per annum.
         Principal  and interest are due on  September  30, 2005.  The notes are
         convertible  into common stock at a  conversion  price equal to $0.3596
         per share of stock at the option of the  holder  prior to the due date.
         There are registration  rights attached to the underlying shares of the
         convertible feature. It has been determined that there is no beneficial
         element of the conversion feature after the allocation of the warrants,
         discussed below, as set forth in EITF 00-27, as the conversion  feature
         approximates the fair value of the shares on the date they were issued.

         Additionally,  the note holders  received  556,123 warrants to purchase
         common stock in connection with the issuance of convertible  notes. The
         warrants  are  exercisable  at $0.5394 per share of stock and are for a
         term of five years.  The fair value  attributable to these warrants was
         $0 as of  September  30,  2004.  The fair  value was  determined  using
         Black-Scholes  option-pricing  method, a 3.50% risk-free interest rate,
         and .0% expected volatility for a nonpublic company.

                                                                              14


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
NOTES TO FINANCIAL STATEMENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------

(8)      INCOME TAXES:

         The provision for income taxes consists of the following:



                                                                 December 31,        December 31,
                                                                     2004                2003
                                                                 ------------        ------------
                                                                                 
                  Current:
                    Federal                                        $      --           $      --
                    State                                               (800)               (800)

                  Deferred taxes                                          --                  --
                                                                   ---------           ---------

                  Income tax provision                             $    (800)          $    (800)
                                                                   =========           =========


         The  difference  between the  provision  for income  taxes and the U.S.
         statutory income tax rate of 34% is as follows:



                                                                 December 31,        December 31,
                                                                     2004                2003
                                                                 ------------        ------------
                                                                                 

                  Tax benefit computed at 34%                      $(182,900)          $ (18,900)
                  Permanent tax difference on option
                    accounting                                        10,000                  --
                  Valuation allowance against net
                    operating losses                                 173,700              19,700
                                                                   ---------           ---------

                  Income tax expense                               $     800           $     800
                                                                   =========           =========


         Deferred  income tax assets  (liabilities)  on the balance sheet are as
         follows:



                                                                 December 31,        December 31,
                                                                     2004                2003
                                                                 ------------        ------------
                                                                                 
                  Net current deferred tax assets-
                    Net operating losses                           $ 193,400           $  19,700

                    Valuation allowance                             (193,400)            (19,700)
                                                                   ---------           ---------

                    Net deferred tax assets (liabilities)          $      --           $      --
                                                                   =========           =========


         During the year ending  December 31, 2004,  the Company  increased  its
         valuation   allowance  $173,700  against  deferred  income  taxes.  The
         valuation  allowance  reduces  deferred  tax  assets to an amount  that
         represents  management's  best estimates of the amount of such deferred
         income taxes, that more likely than not, will be realized.  Realization
         of the deferred tax assets is dependent on  sufficient  future  taxable
         income during the period that temporary  differences and  carryforwards
         are expected to be available to reduce taxable income.

                                                                              15


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
NOTES TO FINANCIAL STATEMENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------

(8)      INCOME TAXES (CONTINUED):

         At December 31,  2004,  the Company had  approximately  $600,000 of net
         operating  losses (NOL)  carryforwards to offset against future income.
         If 50% or more of ownership of the Company changes hands in the future,
         the NOL may be  subject to  limitation  on how much of the NOL could be
         utilized  in any given  year.  The NOL will expire in the year 2023 for
         federal purposes.

(9)      STOCKHOLDERS' DEFICIT:

         COMMON STOCK:

                  The Company was  incorporated  in the State of  California  on
                  February 1, 2002.  The Company was  originally  authorized  to
                  issue  25,000  shares  of  stock.  On  March  3,  2004,  a new
                  corporation was incorporated in Delaware with a par value of $
                  .001 per share with 20,000,000 shares authorized.  On June 17,
                  2004,  the  two   corporations   were  merged  in  a  tax-free
                  reorganization   with  the  Delaware   corporation  being  the
                  surviving entity.  This was treated as a recapitalization  for
                  financial  statement  purposes.  Accordingly,  the outstanding
                  stock from inception is shown at the recapitalized amounts.

                  On March 4, 2005, the Company  increased its authorized  stock
                  to 24,000,000, effective with the increase in authorized stock
                  the Company also declared a 1.2-for-1 stock split. Accordingly
                  these  financial  statements   retrospectively  reflect  these
                  changes.

                  Holders  of the  common  stock  are  entitled  to one vote per
                  share.  The  majority  shareholders  (97%) are  subject to the
                  Company's  right  of first  refusal  should  any  stockholders
                  decide to sell shares  unless a public  market  exists for the
                  Company's common stock, the Company is dissolved, or more than
                  65% of the outstanding stock is sold.

         STOCK OPTIONS:

                  In 2004 the Company  adopted the Stock  Option Plan (the Plan)
                  and  reserved  3,000,000  shares of common  stock for issuance
                  under the Plan.

                  Under the Plan,  incentive  options to purchase the  Company's
                  common  stock may be granted to  employees at prices not lower
                  than fair market value at the date of the grant as  determined
                  by the Board of Directors.  Nonstatutory options (options that
                  do  not  qualify  as  incentive  options)  may be  granted  to
                  employees and  consultants at prices no lower that 85% of fair
                  market value at the date of grant as  determined  by the Board
                  of Directors.  In addition,  incentive or nonstatutory options
                  may be granted to persons  owning  more than 10% of the voting
                  power of all  classes of stock at prices no lower than 110% of
                  the fair market  value at the date of grant as  determined  by
                  options  (no longer than ten years from the date of the grant,
                  five years in certain  instances).  Options granted  generally
                  vest at a rate between 25% to 50% per year.

                                                                              16


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
NOTES TO FINANCIAL STATEMENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------

(9)      STOCKHOLDERS' DEFICIT (CONTINUED):

         STOCK OPTIONS (CONTINUED):

                  Activity under the plan is as follows:



                                                                                       Weighted
                                                    Shares                              Average
                                                   Available          Number           Exercise        Aggregate
                                                   For Grant         of Shares           Price           Price
                                                   ----------        ----------       ----------       ----------

                                                                                           
                         Plan Instituted            3,000,000                --               --               --
                         Options Granted           (1,729,800)        1,729,800       $    .5388          932,016
                         Options Exercised                 --                --               --               --
                         Options Expired              164,546          (164,546)           .5388          (88,658)
                                                   ----------        ----------       ----------       ----------

                         Balance at
                           December 31, 2004        1,434,746         1,565,254       $    .5388       $  843,358
                                                   ==========        ==========       ==========       ==========


                  During the year ended  December 31, 2004,  the Company  issued
                  1,069,800  options to purchase  common stock to its  employees
                  and  directors.  The fair value of these  options  was $0 upon
                  issuance.

                  During the years ended  December 31, 2004,  the Company issued
                  660,000 options to purchase common stock for services rendered
                  by  nonemployees.  The fair value of these options was $0 upon
                  issuance.

                  The fair value of  nonemployee  options  issued was determined
                  using the Black-Scholes  method based on assumed volatility of
                  0.0%, an option life equal to ten years, a risk-free  interest
                  rate of 5.5%  based  on the  grant  date  and the  term of the
                  option and assuming no dividends.


                  Total options  under the Plan at December 31, 2004,  comprised
                  the following:



                                                                                      Weighted
                                                                    Number             Average            Number
                                                    Option        Outstanding         Remaining        Exercisable
                                                   Exercise          as of           Contractual          as of
                                                     Price         12/31/04         Life (Years)         12/31/04
                                                   --------       -----------       ------------       --------------

                                                                                                   
                                                    $ .292           905,254            9.50                599,254
                                                      .833           660,000            9.33                165,000
                                                                   ---------                              ---------

                                                                   1,565,254                                764,254
                                                                   =========                              =========


                                                                              17


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
NOTES TO FINANCIAL STATEMENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------

(9)      STOCKHOLDERS' DEFICIT (CONTINUED):

         STOCK OPTIONS (CONTINUED):

                  In addition,  the Company  issued  103,212  options during the
                  year  ended  December  31,  2004,  to a former  employee  in a
                  nonplan  option grant.  The fair value is computed on the date
                  of the grant using the  intrinsic  value method in  accordance
                  with APB  Opinion  No.  25,  "Accounting  for Stock  Issued to
                  Employees";   $30,000  was   recorded  as  a  result  of  this
                  computation.

         WARRANTS:

                  The  following  warrants are each  exercisable  into shares of
                  common stock:



                                                                       Average
                                                                       Weighted
                                                        Number of      Exercise      Aggregate
                                                          Shares        Price          Price
                                                        ---------      --------      ---------

                                                                            
                     Balance at December 31, 2003             --       $    --       $     --
                     Warrants Granted                    556,123        .53941        299,982
                     Warrants Exercised                       --            --             --
                     Warrants Canceled                        --            --             --
                     Warrants Expired                         --            --             --
                                                        --------       -------       --------

                     Balance at December 31, 2004        556,123       $.53941       $299,982
                                                        ========       =======       ========


                  All warrants issued during the year were issued in conjunction
                  with  convertible debt issuance (see Note 7), and all warrants
                  will expire during the fiscal year ending December 31, 2005.

         SHARES RESERVED FOR FUTURE ISSUANCE:

                  The Company  has  reserved  shares of common  stock for future
                  issuance at December 31, 2004:

                     Stock Option Plan                  1,565,254
                     Stock Option Outside of Plan         103,212
                     Stock Warrants                       556,123
                                                        ---------

                     Total                              2,224,589
                                                        =========

                                                                              18


BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.)
(A DEVELOPMENT STAGE COMPANY)
NOTES TO FINANCIAL STATEMENTS
YEARS ENDED DECEMBER 31, 2004 AND 2003
- --------------------------------------------------------------------------------

(10)     LICENSE AGREEMENT:

         In 2003, the Company  entered into a licensing and technology  transfer
         agreement  with a Taiwan  biotech  corporation  wherein  the  rights to
         certain  technology  restricted  to a certain  geographic  region  were
         transferred to the Taiwan  corporation for a period of 10 years,  which
         will  automatically  renew for  periods  of 3 years,  unless a 12-month
         written notice is given by either party to the  agreement.  The license
         agreement was for a one-time fee of $150,000 and future royalties based
         on 10% of future sales. Additional fees may be earned by the Company in
         the future for additional clinical work.

(11)     CONTINGENCIES AND COMMITMENTS:

         The Company  entered into a consulting  agreement with Duncan  Capital,
         LLC to provide certain  financial  consulting  services.  The agreement
         provides that Duncan  Capital,  LLC is to receive  compensation  in the
         form of a cash fee of $100,000 plus warrants  exercisable at a price of
         $0.010  equal  to  3.675%  of the  fully-diluted  capital  stock of the
         Company after a successful reverse merger. In addition, Duncan Capital,
         LLC will receive  compensation  of warrants  exercisable at $0.6473 per
         share of stock in an  amount  equal to 10% of the  aggregate  number of
         fully- diluted shares of common stock converted by the convertible note
         payable  holders.  The term of the  warrants  will be for  five  years.
         Duncan  Capital,  LLC  will  receive  10% of the  aggregate  number  of
         fully-diluted  shares of common  stock for any debt  financing  that it
         arranges.  The strike price of the warrants will be equal to the strike
         price negotiated with the debt holders.

(12)     SUBSEQUENT EVENTS:

         During March 2005, the Company increased the shares available under the
         Stock Option Plan from 3,000,000 shares to 3,600,000.

         During April 2005,  the Company closed a private  placement  memorandum
         wherein   approximately   $8,095,500   was  raised  for   approximately
         16,191,000 shares of common stock and approximately  4,047,500 warrants
         to purchase shares of common stock to investors and 3,688,730  warrants
         to others.

         On April 6, 2005,  the Company  completed a reverse merger with Lighten
         Up Enterprises International,  Inc., a public company, whereby a newly-
         created,  wholly-owned subsidiary of the public company merged with and
         into the Company in a tax free  exchange,  with the Company  surviving.
         Following the reverse merger, the Company is a wholly-owned  subsidiary
         of the public company.  The stock of the public company continues to be
         quoted  on the  OTC  Bulletin  Board  under  the  symbol  LTUP.OB.  The
         stockholders  of the  Company  received  stock  of the  public  company
         representing  approximately  90.4%  of  the  common  stock  outstanding
         immediately after the reverse merger.

         Also,  during  April 2005,  the  convertible  debt  holders  elected to
         convert  $450,000 of the  convertible  debt to common stock pursuant to
         the terms of the note.

         Subsequent  to year end,  the  Company  executed  an  agreement  with a
         university  to  conduct  clinical  coordinating  services  as part of a
         clinical  trial of  certain of its  drugs.  The cost of the  service is
         approximately  $800,000.  The  services  will  commence  only  when the
         Company  provides the neccesary  materials to start the clinical trial,
         which is expected in Fall of 2005. Payments will be made quarterly,  as
         the clinical trial progresses.

         As of June 28, 2005, the Company,  Bionovo,  Inc.,  changed its name to
         Bionovo Biopharmaceuticals, Inc.

                                                                              19



BIONOVO, INC. (FORMERLY LIGHTEN UP ENTERPRISES INTERNATIONAL, INC.)
AND SUBSIDIARIES PRO FORMA COMBINED FINANCIAL STATEMENTS

The following unaudited pro forma condensed combined balance sheet aggregates
the balance sheet of Bionovo, Inc. (formerly Lighten Up Enterprises
International, Inc.) as of December 31, 2004, and the balance sheet of Bionovo
Biopharmaceuticals, Inc. (formerly Bionovo, Inc.), a Delaware corporation as of
December 31, 2004. The following unaudited pro forma condensed combined
statement of operations aggregates the statement of operations of Bionovo for
the year ended December 31, 2004, and the statement of operations of Bionovo
Biopharmaceuticals for the year ended December 31, 2004. The following unaudited
pro forma condensed combined balance sheet and statement of operations were
prepared giving effect to a transaction completed on April 6, 2005, wherein a
subsidiary of Bionovo, LTUP Acquisition Corp., merged with and into Bionovo
Biopharmaceuticals, with Bionovo Biopharmaceuticals surviving.

On April 6, 2005, we completed a so-called "reverse merger" transaction, in
which we caused LTUP Acquisition Corp., a Delaware corporation and our
newly-created, wholly-owned subsidiary, to be merged with and into Bionovo
Biopharmaceuticals, Inc. (formerly Bionovo, Inc.), a Delaware corporation.
Bionovo Biopharmaceuticals is a drug discovery and development company focusing
on cancer and women's health. As a result of the merger, Bionovo
Biopharmaceuticals became our wholly-owned subsidiary, with Bionovo
Biopharmaceutical's former security holders acquiring a majority of the
outstanding shares of our common stock, par value $0.0001 per share. The reverse
merger was consummated under Delaware law and pursuant to an Agreement of Merger
and Plan of Reorganization, dated April 6, 2005 (the "Merger Agreement").

Immediately prior to the closing of the reverse merger, Bionovo
Biopharmaceuticals completed the closing of a private offering of Units
comprised of its common stock and warrants to purchase its common stock to new
investors. Bionovo Biopharmaceuticals received gross proceeds of $8,095,500 at
the closing of the private offering.

Under the Merger Agreement, at closing, we issued 37,842,448 shares of our
common stock to the former security holders of Bionovo Biopharmaceuticals,
representing approximately 90.4% of our outstanding common stock following the
merger, in exchange for 100% of the outstanding capital stock of Bionovo
Biopharmaceuticals, subject to appraisal rights of former Bionovo
Biopharmaceuticals stockholders. In addition, all warrants issued by Bionovo
Biopharmaceuticals to purchase shares of Bionovo Biopharmaceuticals common stock
outstanding immediately prior to the merger were amended to become warrants to
purchase common stock of Bionovo on the same terms and conditions as those
warrants issued by Bionovo Biopharmaceuticals, including the number of shares
issuable upon the exercise of the warrants. Immediately prior to the closing of
the merger, all outstanding Bionovo Biopharmaceuticals warrants were exercisable
for 6,445,394 shares of Bionovo Biopharmaceuticals common stock, which included
the warrants issued in Bionovo Biopharmaceuticals private offering. At the
closing of the merger, these warrants were amended to become warrants to
purchase the same number of shares of Bionovo common stock. Further, all stock
options issued by Bionovo Biopharmaceuticals under its Stock Incentive Plan or
otherwise to purchase shares of Bionovo Biopharmaceuticals common




stock outstanding immediately prior to the merger were amended to become stock
options to purchase common stock of Bionovo on the same terms and conditions as
those stock options issued by Bionovo Biopharmaceuticals, including the number
of shares issuable upon the exercise of such stock options. Immediately prior to
the closing of the merger, all outstanding Bionovo Biopharmaceuticals stock
options were exercisable for 1,740,465 shares of Bionovo Biopharmaceuticals
common stock. At the closing of the merger, these stock options were amended to
become stock options to purchase the same number of shares of Bionovo common
stock. We did not have any stock options outstanding as of immediately prior to
the closing of the merger.

The following pro forma condensed balance sheet and statement of operations uses
the assumptions as described in the notes and the historical financial
information available at December 31, 2004. The financial statements of both
Bionovo and Bionovo Biopharmaceuticals at December 31, 2004 are audited.

The  unaudited  pro forma  condensed  combined  balance  sheet and  statement of
operations should be read in conjunction with the separate financial  statements
and  related  notes  thereto  of Bionovo  and  Bionovo  Biopharmaceuticals.  The
unaudited pro forma condensed combined balance sheet and statement of operations
are not  necessarily  indicative  of the  condensed  combined  balance sheet and
statement of  operations  which might have existed for the periods  indicated or
the results of operations as they may appear now or in the future.


BIONOVO, INC. (FORMERLY LIGHTEN UP ENTERPRISES INTERNATIONAL, INC.) AND
SUBSIDIARIES PRO FORMA CONDENSED COMBINED BALANCE SHEETS
As of December 31, 2004
(Unaudited)



                                                                 Bionovo
                                                   Bionovo  Biopharmaceuticals    ADJUSTMENTS   COMBINED
                                                   ---------------------------    -----------   ---------
                                                                                   
ASSETS

CURRENT ASSETS:
  Cash and cash equivalents                               37       $ 196,013             --      196,050
  Due from officers                                       --           1,796             --        1,796
  Prepaid expenses and other current assets               --              --             --           --
                                                   -------------------------      ---------    ---------

         Total current assets                             37         197,809             --      197,846

PROPERTY AND EQUIPMENT,
  net of accumulated depreciation                         --           9,859             --        9,859

OTHER ASSETS:
  Deferred loan costs
     net of accumulated amortization                      --          65,551             --       65,551
  Patent costs                                            --          11,264             --       11,264
                                                   -------------------------      ---------    ---------

                                                   $      37       $ 284,483      $      --    $ 284,520
                                                   =========================      =========    =========

LIABILITIES AND STOCKHOLDERS' DEFICIT

CURRENT LIABILITIES:
   Accounts payable and accrued expenses             131,169       $ 163,613       (131,169)(1)  163,613
   Accrued pension payable                                --          52,000             --       52,000
   Deferred revenue                                       --          15,000             --       15,000
   Convertible notes payable                              --         500,000             --      500,000
                                                   -------------------------      ---------    ---------

         Total current liabilities                   131,169         730,613       (131,169)     730,613
                                                   -------------------------      ---------    ---------

DEFERRED REVENUE                                           0         117,500             --      117,500
                                                   -------------------------                   ---------

LONG TERM LIABILITIES
   Accrued interest - related party                   41,152              --        (41,152)          --
                                                   -------------------------      ---------    ---------

STOCKHOLDERS' DEFICIT:
  Common stock, $0.001 par value:
  Additional paid-in capital                           2,504          24,400         (2,104)(2)   24,800
  Accumulated deficit                                221,403           5,600       (221,766)(2)    5,237
                                                    (396,191)       (593,630)       396,191     (593,630)
                                                   -------------------------      ---------    ---------

          Total stockholders' deficit               (172,284)       (563,630)       172,321     (563,593)
                                                   -------------------------      ---------    ---------

                                                   $      37       $ 284,483             --      284,520
                                                   =========================      =========    =========


(1)  Bionovo related party forgave loans.

(2)  Bionovo shareholders surrendered 21,040,000 shares.


SEE  ACCOMPANYING  NOTES TO UNAUDITED  PRO FORMA  CONDENSED  COMBINED  FINANCIAL
STATEMENTS


Unaudited Pro Forma Condensed Combined Financial Statements of Bionovo, Inc.
(formerly Lighten Up Enterprises International, Inc.) and Subsidiaries:

The following unaudited pro forma condensed combined financial statements give
effect to the acquisition of Bionovo Biopharmaceuticals by the Company using the
purchase method of accounting and include the pro forma adjustments described in
the accompanying notes.

The following unaudited pro forma condensed combined balance sheet as of
December 31, 2004, and combined statements of operations for the year ended
December 31, 2004 are based on the historical financial statements of Bionovo
and Bionovo Biopharmaceuticals after giving the effect to the acquisition of
Bionovo Biopharmaceuticals under the purchase method of accounting.


BASIS OF PRESENTATION

The unaudited pro forma condensed combined financial statements as of December
31, 2004 record the acquisition transaction as if the acquisition had taken
place on January 1, 2004. The unaudited pro forma condensed combined balance
sheet is




presented to give effect to the acquisition as if it occurred on December 31,
2004, and combines the balance sheets of Bionovo and Bionovo Biopharmaceuticals
as of that date. The pro forma information does not purport to be indicative of
the results that would have been reported if the above transactions had been in
effect for the periods presented or which may result in the future.

BIONOVO, INC. (FORMERLY LIGHTEN UP ENTERPRISES INTERNATIONAL, INC.) AND
SUBSIDIARIES PRO FORMA CONDENSED COMBINED STATEMENTS OF OPERATIONS
YEAR ENDED DECEMBER 31, 2004
(Unaudited)



                                                          Bionovo
                                      Bionovo       Biopharmaceuticals    ADJUSTMENTS     COMBINED
                                      --------------------------------    -----------    -----------
                                                                             
REVENUE                               $     4,087          $    45,240         (4,087)        45,240

COST OF SALES                                  --                   --             --             --
                                      --------------------------------    -----------    -----------

GROSS PROFIT                                4,087               45,240         (4,087)        45,240
                                      --------------------------------    -----------    -----------

OPERATING EXPENSES:
  Research and development                     --              275,600             --        275,600
  General and administrative               31,077              277,433        (21,077)       287,433
  Sales and marketing                      39,548                  500        (39,548)           500
                                      --------------------------------    -----------    -----------

          Total operating expenses         70,625              553,533        (60,625)       563,533
                                      --------------------------------    -----------    -----------

LOSS FROM OPERATIONS                      (66,538)            (508,293)        56,538       (518,293)

OTHER INCOME (EXPENSE):
  Forgiveness of loan payable                                                      --             --
  Interest expense                         (2,061)             (28,855)         2,061        (28,855)
                                      --------------------------------    -----------    -----------

          Total other income               (2,061)             (28,855)         2,061        (28,855)

LOSS BEFORE INCOME
 TAXES                                    (68,599)            (537,148)        58,599       (547,148)

PROVISION FOR INCOME TAXES                     --                 (800)            --           (800)
                                      --------------------------------    -----------    -----------

NET LOSS                              $   (68,599)         $  (537,948)   $    58,599    $  (547,948)
                                      ================================    ===========    ===========

NET LOSS PER SHARE                    $     (0.00)         $     (0.03)   $      0.00    $     (0.01)
                                      ================================    ===========    ===========

WEIGHTED AVERAGE SHARES OUTSTANDING    25,040,000           20,400,000     21,040,000     24,400,000
                                      ================================    ===========    ===========


SEE  ACCOMPANYING  NOTES TO UNAUDITED  PRO FORMA  CONDENSED  COMBINED  FINANCIAL
STATEMENTS


SUMMARY OF TRANSACTION

On April 6, 2005, we completed a so-called "reverse merger" transaction, in
which we caused LTUP Acquisition Corp., a Delaware corporation and our
newly-created, wholly-owned subsidiary, to be merged with and into Bionovo
Biopharmaceuticals, Inc. (formerly Bionovo, Inc.), a Delaware corporation.
Bionovo Biopharmaceuticals is a drug discovery and development company focusing
on cancer and women's health. As a result of the merger, Bionovo
Biopharmaceuticals became our wholly-owned subsidiary, with Bionovo
Biopharmaceuticals' former security holders acquiring a majority of the
outstanding shares of our common stock, par value $0.0001 per share. The reverse
merger was consummated under Delaware law and pursuant to an Agreement of Merger
and Plan of Reorganization, dated April 6, 2005.

Pursuant to the Merger Agreement, at closing, stockholders of Bionovo
Biopharmaceuticals received one share of our common stock for each share of
Bionovo Biopharmaceuticals common stock in the merger. As a result, at closing
we issued 37,842,448 shares of our common stock to the former stockholders of
Bionovo Biopharmaceuticals, representing approximately 90.4% of our outstanding
common stock following the merger, in exchange for 100% of the outstanding
capital stock of Bionovo Biopharmaceuticals. The consideration issued in the
merger was determined as a result of arm's-length negotiations between the
parties. As of April 6, 2005, our board of directors also approved a change in
our certifying accountant. Prior to effecting the change of our certifying
accountant, the board of directors determined to retain our current accountants
in connection with the preparation of our Form 10-QSB for the quarter ended
March 31, 2005.

The shares of our common stock issued to former holders of Bionovo
Biopharmaceuticals common stock in connection with the merger, including the
investors in the Bionovo Biopharmaceuticals private offering, and the shares of
our common stock issued in our subsequent private offering, were not registered
under the Securities Act of 1933 in reliance upon the exemption from
registration provided by Section 4(2) of that Act and Regulation D promulgated
under that section, which exempts transactions by an issuer not involving any
public offering. These shares may not be offered or sold in the United States
absent registration or an applicable exemption from the registration
requirements. Certificates representing these shares contain a legend stating
the same.


PRO FORMA ADJUSTMENTS

The pro forma combined balance sheet as of December 31, 2004 gives effect
to the forgiveness of a liability of $131,169, and accrued interest of $41,152,
as the related party that provided the loan agreed to forgive the loan and all
accrued interest pursuant to the reverse merger.

The pro forma condensed combined statements of operations for the year ended
December 31, 2004, gives effect to the disposal of the cook book business.

Additionally, shareholders of 21,040,000 shares surrendered shares to treasury
pursuant to the reverse merger.


PRO FORMA NET LOSS PER SHARE

The pro forma basis and dilutive net loss per share are based on the weighted
average number of shares of pro forma Bionovo's common stock as if the shares
issued to acquire Bionovo Biopharmaceuticals had taken place at the beginning of
the year. Dilutive shares are not included in the computation of pro forma
dilutive net loss per share as their effect would be anti-dilutive.



                                 EXHIBIT INDEX

EXHIBIT NO.        DESCRIPTION
- -----------        -----------
10.11         Licensing & Technology Transfer Agreement, dated November 6, 2003,
              with United Biotech Corporation (certain terms of this agreement
              have been omitted and are subject to a request for confidential
              treatment with the SEC)