UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 ------------------------------------------------------------ FORM 8-K/A (Amendment No. 5) CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 ------------------------------------------------------------------- Date of Report (Date of earliest event reported): April 6, 2005 BIONOVO, INC. ------------------------------------------ (Exact Name of Registrant as Specified in Charter) DELAWARE 000-50073 87-0576481 - ---------------------------- ------------------------ ------------------- (State or other jurisdiction (Commission File Number) (IRS Employer of incorporation) Identification No.) 5858 Horton Street, Suite 375 Emeryville, California 94608 ----------------------------- ---------- (Address of principal executive offices) (Zip Code) Registrant's telephone number, including area code: (510) 601-2000 LIGHTEN UP ENTERPRISES INTERNATIONAL, INC. 2200 Powell Street, Suite 675 Emeryville, California 94608 ------------------------------------------ (Former name or former address, if changed since last report) ================================================================================ Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions: [ ] Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) [ ] Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 DFR 240.14a-12) [ ] Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) [ ] Pre-commencement communications pursuant to Rule 13e-4 (c) under the Exchange Act (17 CFR 240.13e-4(c)) CURRENT REPORT ON FORM 8-K/A (AMENDMENT NO. 5) BIONOVO, INC. EXPLANATORY NOTE: This Amendment No. 5 on Form 8-K/A amends the Current Report on Form 8-K/A, Amendment No. 4, dated April 6, 2005, of Bionovo, Inc., a Delaware corporation (formerly Lighten Up Enterprises International, Inc., a Nevada Corporation) ("Registrant"), filed with the Securities and Exchange Commission ("SEC") on September 15, 2005, which amended the Current Report on Form 8-K/A, Amendment No. 3, dated April 6, 2005, of the Registrant filed with the SEC on June 27, 2005, which amended the Current Report on Form 8-K/A, Amendment No. 2, dated April 6, 2005, of the Registrant filed with the SEC on June 22, 2005, which amended the Current Report on Form 8-K/A, Amendment No. 1, dated April 6, 2005, of the Registrant filed with the SEC on June 3, 2005, which amended the Current Report on Form 8-K dated April 6, 2005 of the Registrant filed with the SEC on April 8, 2005. This Amendment No. 5 is being filed to re-file a previously identified material contract under Item 9.01(c). There are no changes to the financial information included in Items 9.01(a) and (b). ITEM 9.01. FINANCIAL STATEMENTS AND EXHIBITS (a) FINANCIAL STATEMENTS OF BUSINESSES ACQUIRED. In accordance with Item 9.01(a), attached hereto are the audited financial statements of Bionovo Biopharmaceuticals, Inc. (formerly Bionovo, Inc.) for the fiscal years ended December 31, 2004 and 2003. (b) PRO FORMA FINANCIAL INFORMATION. In accordance with Item 9.01(b), attached hereto are the pro forma financial statements of Bionovo Biopharmaceuticals, Inc. (formerly Bionovo, Inc.) (c) EXHIBITS. The exhibits listed in the following Exhibit Index are filed as part of this Report. EXHIBIT NO. DESCRIPTION ----------- ----------- 2.1 Agreement of Merger and Plan of Reorganization, dated as of April 6, 2005, among Lighten Up Enterprises International, Inc., LTUP Acquisition Corp. and Bionovo, Inc. (incorporated herein by reference from Exhibit 2.1 to the Registrant's Form 8-K filed with the SEC on April 8, 2005) 3.1(i) Articles of Incorporation of the Registrant (incorporated herein by reference from Exhibit 3.1(i) to the Registrant's Form 10-SB filed with the SEC on November 7, 2002) 3.1(ii) Restated and Amended Articles of Incorporation of the Registrant (incorporated herein by reference from Exhibit 3.1(ii) to the Registrant's Form 10-SB filed with the SEC on November 7, 2002) 3.1(iii) Certificate of Amendment to Restated and Amended Articles of Incorporation of the Registrant (incorporated herein by reference from Exhibit 3.1(iii) to the Registrant's Form 10-SB filed with the SEC on November 7, 2002) 3.2 By-laws of the Registrant (incorporated herein by reference from Exhibit 3.2 to the Registrant's Form 10-SB filed with the SEC on November 7, 2002) 4.1 Form of Private Placement Warrant (incorporated herein by reference from Exhibit 4.1 to the Registrant's Form 8-K filed with the SEC on May 11, 2005) 10.1 Form of Private Placement Subscription Agreement (incorporated herein by reference from Exhibit 10.1 to the Registrant's Form 8-K filed with the SEC on May 11, 2005) 10.2 Form of Private Placement Investor Questionnaire (incorporated herein by reference from Exhibit 10.2 to the Registrant's Form 8-K filed with the SEC on May 11, 2005) 10.3 Form of Private Placement Registration Rights Agreement (incorporated herein by reference from Exhibit 10.3 to the Registrant's Form 8-K filed with the SEC on May 11, 2005) 10.4 Form of Private Placement Acknowledgement and Amendment (incorporated herein by reference from Exhibit 10.4 to the Registrant's Form 8-K filed with the SEC on May 11, 2005) 10.5 Registration Rights Agreement, dated September 30, 2004 (incorporated herein by reference from Exhibit 10.5 to the Registrant's Form 8-K/A, Amendment No. 1, filed with the SEC on June 3, 2005) 10.6 Stock Incentive Plan, as amended (incorporated herein by reference from Exhibit 5 to the Registrant's Schedule 14C filed with the SEC on June 3, 2005) 10.7 Employment Agreement, dated July 1, 2004, between Bionovo, Inc. and Isaac Cohen (incorporated herein by reference from Exhibit 10.7 to the Registrant's Form 8-K/A, Amendment No. 1, filed with the SEC on June 3, 2005) 10.8 Assignment and Assumption Agreement, dated April 6, 2005, among Registrant, Bionovo, Inc. and Isaac Cohen regarding Employment Agreement (incorporated herein by reference from Exhibit 10.8 to the Registrant's Form 8-K/A, Amendment No. 1, filed with the SEC on June 3, 2005) 10.9 Employment Agreement, dated July 1, 2004, between Bionovo, Inc. and Mary Tagliaferri (incorporated herein by reference from Exhibit 10.9 to the Registrant's Form 8-K/A, Amendment No. 1, filed with the SEC on June 3, 2005) 10.10 Assignment and Assumption Agreement, dated April 6, 2005, among the Registrant, Bionovo, Inc. and Mary Tagliaferri regarding Employment Agreement (incorporated herein by reference from Exhibit 10.10 to the Registrant's Form 8-K/A, Amendment No. 1, filed with the SEC on June 3, 2005) 10.11 Licensing & Technology Transfer Agreement, dated November 6, 2003, with United Biotech Corporation (certain terms of this agreement have been omitted and are subject to a request for confidential treatment with the SEC) 21.1 Subsidiaries of Registrant (previously filed) SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized. Date: October 19, 2005 LIGHTEN UP ENTERPRISES INTERNATIONAL, INC. By: /s/ James P. Stapleton --------------------------------- James P. Stapleton Chief Financial Officer BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) TABLE OF CONTENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- PAGE ---- REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM 1 FINANCIAL STATEMENTS: Balance Sheets 2 Statements of Operations 3 Statements of Stockholders' Deficit 4 Statements of Cash Flows 5 Notes to Financial Statements 6-20 REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM Board of Directors BioNovo Biopharmaceuticals, Inc. (formerly BioNovo, Inc.) Emeryville, California We have audited the accompanying balance sheets of BioNovo Biopharmaceuticals, Inc. (formerly BioNovo, Inc.) (a Development Stage Company) as of December 31, 2004 and 2003, and the related statements of operations, stockholders' deficit, and cash flows for the years then ended and from inception, February 1, 2002, through December 31, 2004. These financial statements are the responsibility of the Company's management. Our responsibility is to express an opinion on these financial statements based on our audits. We conducted our audits in accordance with the standards of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audits to obtain reasonable assurance about whether the financial statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements. An audit also includes assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion. In our opinion, the financial statements referred to above present fairly, in all material respects, the financial position of BioNovo Biopharmaceuticals, Inc. (formerly BioNovo, Inc.) as of December 31, 2004 and 2003, and from inception, February 1, 2002, through December 31, 2004, and the results of its operations and its cash flows for the years then ended in conformity with accounting principles generally accepted in the United States of America. /s/ Stonefield Josephson, Inc. CERTIFIED PUBLIC ACCOUNTANTS San Francisco, California April 8, 2005, except for paragraph 6 of Note 12 which its date is June 28, 2005 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) BALANCE SHEETS - -------------------------------------------------------------------------------- December 31, December 31, 2004 2003 ------------ ------------ ASSETS CURRENT ASSETS: Cash and cash equivalents $ 196,013 $ 73,867 Due from officers 1,796 -- Prepaid expenses and other current assets -- 15,156 --------- --------- Total current assets 197,809 89,023 PROPERTY AND EQUIPMENT, net of accumulated depreciation 9,859 2,795 OTHER ASSETS: Deferred loan costs net of accumulated amortization 65,551 -- Patent pending costs 11,264 -- --------- --------- $ 284,483 $ 91,818 ========= ========= LIABILITIES AND STOCKHOLDERS' DEFICIT CURRENT LIABILITIES: Accounts payable and accrued expenses $ 163,613 $ -- Accrued pension payable 52,000 -- Deferred revenue 15,000 15,000 Convertible notes payable 500,000 -- --------- --------- Total current liabilities 730,613 15,000 --------- --------- DEFERRED REVENUE 117,500 132,500 --------- --------- STOCKHOLDERS' DEFICIT: Common stock, $0.001 par value: Authorized shares - 24,400,000 issued and outstanding common shares - 24,400,000 24,400 24,400 Additional paid-in capital 5,600 (24,400) Accumulated deficit (593,630) (55,682) --------- --------- Total stockholders' deficit (563,630) (55,682) --------- --------- $ 284,483 $ 91,818 ========= ========= The accompanying notes form an integral part of these financial statements. 2 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) STATEMENTS OF OPERATIONS - -------------------------------------------------------------------------------- Accumulated from Year Ended Year Ended February 1, 2002 December 31, December 31, (Date of Inception) to 2004 2003 December 31, 2004 ------------ ------------ ---------------------- REVENUE $ 45,240 $ 2,500 $ 47,740 ------------ ------------ ------------ OPERATING EXPENSES: Research and development 275,600 22,179 297,779 General and administrative 277,433 35,203 312,636 Sales and marketing 500 -- 500 ------------ ------------ ------------ Total operating expenses 553,533 57,382 610,915 ------------ ------------ ------------ LOSS FROM OPERATIONS (508,293) (54,882) (563,175) OTHER INCOME (EXPENSE): Interest expense, net of $495 in 2004, and $0 in 2003 of interest income (28,855) -- (28,855) ------------ ------------ ------------ LOSS BEFORE INCOME TAXES (537,148) (54,882) (592,030) PROVISION FOR INCOME TAXES (800) (800) (1,600) ------------ ------------ ------------ NET LOSS $ (537,948) $ (55,682) $ (593,630) ============ ============ ============ NET LOSS PER SHARE $ (0.02) $ (0.00) $ (0.02) ============ ============ ============ WEIGHTED AVERAGE SHARES OUTSTANDING 24,400,000 24,400,000 24,400,000 ============ ============ ============ The accompanying notes form an integral part of these financial statements. 3 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) STATEMENTS OF STOCKHOLDERS' DEFICIT INCEPTION THROUGH DECEMBER 31, 2004 - -------------------------------------------------------------------------------- Common Stock Accumulated ---------------------------- Additional Deficit During Number of Paid-In Development Shares Amount Capital Stage Total ---------- ---------- ---------- ---------- ---------- BALANCE AT INCEPTION (February 1, 2002)-Adjusted to reflect effect of stock split on June 17, 2004 and reverse merger on April 6, 2005 24,400,000 $ 2,440 $ (2,440) $ -- $ -- ---------- ---------- ---------- ---------- ---------- BALANCE, December 31, 2002 24,400,000 2,440 (2,440) -- -- NET LOSS (55,682) (55,682) ---------- ---------- ---------- ---------- ---------- BALANCE, December 31, 2003 24,400,000 2,440 (2,440) (55,682) (55,682) NONCASH COMPENSATION EXPENSE FOR OPTIONS ISSUED -- -- 30,000 -- 30,000 NET LOSS (537,948) (537,948) ---------- ---------- ---------- ---------- ---------- BALANCE, December 31, 2004 24,400,000 $ 2,440 $ 27,560 $ (593,630) $ (563,630) ========== ========== ========== ========== ========== The accompanying notes form an integral part of these financial statements. 4 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) STATEMENTS OF CASH FLOWS - -------------------------------------------------------------------------------- Accumulated from Year Ended Year Ended February 1, 2002 December 31, December 31, (Date of Inception) to 2004 2003 December 31, 2004 ------------ ------------ ---------------------- CASH FLOWS PROVIDED BY (USED FOR) OPERATING ACTIVITIES: Net loss $(537,948) $ (55,682) $(593,630) --------- --------- --------- ADJUSTMENTS TO RECONCILE NET LOSS TO NET CASH PROVIDED BY (USED FOR) OPERATING ACTIVITIES: Depreciation 1,821 3,090 4,911 Amortization of note discount 21,850 -- 21,850 Noncash compensation expense for options issued 30,000 30,000 CHANGES IN ASSETS AND LIABILITIES: (INCREASE) DECREASE IN ASSETS: Prepaid expenses 15,156 (15,156) -- INCREASE (DECREASE) IN LIABILITIES: Accounts payable and accrued expenses 163,613 -- 163,613 Deferred tax liability (15,000) 147,500 132,500 Accrued pension payable 52,000 -- 52,000 --------- --------- --------- Total adjustments 269,440 135,434 404,874 --------- --------- --------- Net cash provided by (used for) operating activities (268,508) 79,752 (188,756) --------- --------- --------- CASH FLOWS USED FOR INVESTING ACTIVITIES: Acquisition of intangible assets (11,264) -- (11,264) Acquisition of fixed assets (8,885) (5,885) (14,770) Advance to officers (1,796) -- (1,796) --------- --------- --------- Net cash used for investing activities (21,945) (5,885) (27,830) --------- --------- --------- CASH FLOWS PROVIDED BY FINANCING ACTIVITIES: Proceeds from convertible notes payable 500,000 -- 500,000 Payments for financing costs for convertible notes (87,401) -- (87,401) --------- --------- --------- Net cash provided by financing activities 412,599 -- 412,599 --------- --------- --------- NET INCREASE IN CASH 122,146 73,867 196,013 CASH, beginning of year 73,867 -- -- --------- --------- --------- CASH, end of year $ 196,013 $ 73,867 $ 196,013 ========= ========= ========= SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION: Interest paid $ -- $ -- $ -- ========= ========= ========= Income taxes paid $ 800 $ 800 $ 1,600 ========= ========= ========= SUPPLEMENTAL DISCLOSURE OF NONCASH INVESTING INVESTING ACTIVITIES- Noncash compensation expense for options issued $ 30,000 $ -- $ 30,000 ========= ========= ========= The accompanying notes form an integral part of these financial statements. 5 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) NOTES TO FINANCIAL STATEMENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- (1) BUSINESS AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES: FORMATION AND BUSINESS OF THE COMPANY: BioNovo, Inc., (the "Company") was incorporated in California on February 2, 2002. A new company was formed and incorporated in Delaware on March 3, 2004, and was merged and recapitalized with the California corporation. The Company is a drug discovery and development company focusing on cancer and women's health, primarily using select plant extracts to screen against well understood therapeutic targets. The Company has a unique developmental pathway that leverages understanding of modern drug discovery with experience in clinical development. DEVELOPMENT STAGE COMPANY: The Company has not generated any significant revenue since inception. The accompanying financial statement has, therefore, been prepared using the accounting formats prescribed for a development stage enterprise (DSE). Although the Company has recognized some revenue, the Company still believes it is devoting substantial efforts on developing the business and, therefore, still qualifies as a DSE. USE OF ESTIMATES: The preparation of financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the amounts in the financial statements and accompanying notes. Actual results could differ from those estimates. FAIR VALUE OF FINANCIAL INSTRUMENTS: The carrying amount of cash equivalents, accounts receivable, accounts payable, and notes payable approximates their fair value either due to the short duration to maturity or a comparison to market interest rates for similar instruments. CASH: CASH EQUIVALENTS The Company considers all highly liquid investments purchased with an original maturity of three months or less at the time of purchase to be cash equivalents. The Company maintains the majority of its cash and cash equivalents at two major banks. CASH CONCENTRATION The Company maintains its cash in bank accounts, which at times may exceed federally insured limits. The Company has not experienced any losses on such accounts. 6 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) NOTES TO FINANCIAL STATEMENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- (1) BUSINESS AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED): PROPERTY AND EQUIPMENT: Fixed assets are stated at cost less accumulated depreciation. Depreciation is calculated using the straight-line method over the estimated useful lives of the assets, which generally range from three to five years. IMPAIRMENT OF LONG-LIVED ASSETS: The Company assesses the impairment of its long-lived assets periodically in accordance with the provisions of Statement of Financial Accounting Standards ("SFAS") 144, "Accounting for the Impairment and Disposal of Long-Lived Assets". Whenever events or changes in circumstances indicate that the carrying amounts of long-lived assets may not be recoverable, the Company will compare undiscounted net cash flows estimated to be generated by those assets to the carrying amount of those assets. When these undiscounted cash flows are less than the carrying amounts of the assets, the Company will record impairment losses to write the asset down to fair value, measured by the discounted estimated net future cash flows expected to be generated from the assets. To date there has been no impairment. DEFERRED LOAN COSTS: Deferred loan costs relate to the direct costs related to obtaining debt financing for the Company and will be amortized over the life of the debt using the effective interest method of accounting. PATENT PENDING COSTS: Intangible assets consist of patent licensing costs to date. If the patents are awarded, the costs will be amortized over the term of the patents. If the patents are not awarded, the costs related to those patents will be expensed in the period that determination is made. INCOME TAXES: Deferred income taxes are recognized for the tax consequences in future years of differences between the tax basis of assets and liabilities and their financial reporting amounts at each year end based on enacted tax laws and statutory tax rates applicable to the periods in which the differences are expected to affect taxable income. Valuation allowances are established, when necessary, to reduce deferred tax assets to the amount expected to be realized. DEFERRED REVENUE: Deferred revenue consists of upfront fees received for technology licensing that have not yet been recognized or earned. 7 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) NOTES TO FINANCIAL STATEMENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- (1) BUSINESS AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED): CONVERTIBLE NOTES PAYABLE: In January 2001, the Financial Accounting Standards Board Emerging Issues Task Force issued EITF 00-27 effective for convertible debt instruments issued after November 16, 2000. This pronouncement requires the use of the intrinsic value method for recognition of the detachable and imbedded equity features included with indebtedness and requires amortization of the amount associated with the convertibility feature over the life of the debt instrument rather than the period for which the instrument becomes convertible. STOCK-BASED COMPENSATION: The Company accounts for stock-based compensation in accordance with Accounting Principles Board ("APB") Opinion No. 25, "Accounting for Stock Issued to Employees", and complies with the disclosure provisions of SFAS No. 123, "Accounting for Stock-Based Compensation". Under APB No. 25, compensation cost is recognized over the vesting period based on the excess, if any, on the date of grant of the market value of the Company's shares over the employee's exercise price. When the exercise price of the option is less than the fair value price of the underlying shares on the grant date, deferred stock compensation is recognized and amortized to expense in accordance with Financial Accounting Standards Board ("FASB") Interpretation No. 44 over the vesting period of the individual options. Accordingly, if the exercise price of the Company's employee options equals or exceeds the market price of the underlying shares on the date of grant, no compensation expense is recognized. Options or shares awards issued to nonemployees are valued using the Black-Scholes pricing model and expensed over the period services are provided. In December 2002, the FASB issued SFAS No. 148, "Accounting for Stock-Based Compensation - Transition and Disclosure", which amends SFAS No. 123, "Accounting for Stock-Based Compensation", to provide alternative methods of transition for a voluntary change to the fair value-based method of accounting for stock-based employee compensation. In addition, SFAS No. 148 expands the disclosure requirements of SFAS No. 123 to require more prominent disclosures in both annual and interim financial statements about the method of accounting for stock-based employee compensation and the effect of the method used on reported results. The transition provisions of SFAS No. 148 are effective for fiscal years ended after December 15, 2002. The transition provisions do not currently have an impact on the Company's financial position and results of operations as the Company has not elected to adopt the fair value-based method of accounting for stock-based employee compensation under SFAS NO. 123. The disclosure provisions of SFAS No. 148 are effective for financial statements for interim periods beginning after December 15, 2002. The Company adopted the disclosure requirements in the first quarter of fiscal year 2003. 8 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) NOTES TO FINANCIAL STATEMENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- (1) BUSINESS AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED): STOCK-BASED COMPENSATION (CONTINUED): The following table illustrates the effect on net loss and loss per share if the Company had applied the fair value recognition provisions of FASB Statement No. 123, Accounting for Stock-Based Compensation, to Stock-Based Employee Compensation. Years Ended December 31, ------------------------- 2004 2003 --------- --------- Net income (loss) available as reported $(537,948) $ (54,882) Compensation recognized under APB 25 30,000 -- Compensation recognized under SFAS 123 (100,000) -- --------- --------- Pro-forma net income (loss) available $(607,948) $ (54,882) ========= ========= Loss per share, as reported $ (0.026) $ (0.003) ========= ========= Loss per share, pro-forma $ (0.030) $ (0.003) ========= ========= For grants in 2004, the following assumptions were used: (i) no expected dividends; (ii) a risk-free interest rate ranging from 3.5% to 5.5% during the year ended December 31, 2004, (iii) expected volatility 0.0%, and (iv) an expected life of the stated life of the option for options granted in 2004. The fair value was determined using the Black-Scholes option-pricing model. The estimated fair value of grants of stock options and warrants to nonemployees of the Company is charged to expense, if applicable, in the financial statements. These options vest in the same manner as the employee options granted under each of the option plans as described above. REVENUE RECOGNITION: Revenue is generated from collaborative research and development arrangements, technology licenses, and government grants. To date only revenue from technology licenses has been received. Revenue is recognized when the four basic criteria of revenue recognition are met: (i) a contractual agreement exists; (ii) transfer of technology has been completed or services have been rendered; (iii) the fee is fixed or determinable, and (iv) collectibility is reasonably assured. Technology license agreements are for a term of ten years and consist of nonrefundable upfront license fees and royalty payments. In accordance with Staff Accounting Bulletin 104, nonrefundable upfront license fees are recognized over the license term using the straight-line method of accounting when the technology is transferred or accessed, provided that the technology transferred or accessed is not dependent on the outcome of the Company's continuing research and development efforts. 9 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) NOTES TO FINANCIAL STATEMENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- (1) BUSINESS AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED): RESEARCH AND DEVELOPMENT: Research and development expenses include internal and external costs. Internal costs include salaries and employment related expenses and allocated facility costs. External expenses consist of costs associated with outsourced clinical research organization activities, sponsored research studies, product registration, and investigator sponsored trials. In accordance with SFAS No. 2, "ACCOUNTING FOR RESEARCH DEVELOPMENT COSTS", all such costs are charged to expense as incurred. (2) RECENT ACCOUNTING PRONOUNCEMENTS: In December 2004, the Financial Accounting standards Board ("FASB") issued SFAS No. 123(R), "Share-Based Payment". SFAS No. 123(R) addresses accounting for share-based payments to employees, including grants of employee stock options. Under the new standard, companies will no longer be able to account for share-based compensation transactions using the intrinsic method in accordance with Accounting Principles Board ("APB") Opinion No. 25, "Accounting for Stock Issued to Employees". Instead, companies will be required to account for such transactions using a fair-value method and recognize the expense in the statement of income. SFAS No. 123(R) will be effective for periods beginning after June 15, 2005, and allows, but does not require, companies to restate the full fiscal year of 2005 to reflect the impact of expensing share-based payment under SFAS No. 123(R). The Company has not yet determined which fair-value method and transitional provision it will follow. However, it expects that the adoption of SFAS No. 123(R) will have a significant impact on its results of operations. The Company does not expect the adoption of SFAS No. 123(R) will impact its overall financial position. There was no impact on net income and net income per share from calculating stock-based compensation costs under the fair value alternative of SFAS No. 123. However, the calculation of compensation cost for share-based payment transactions after the effective date of SFAS 123(R) will be different from the calculation of compensation cost under SFAS No. 123, but such differences have not yet been quantified. In December 2004, the FASB issued SFAS No. 152, "Accounting for Real Estate Time-Sharing Transactions - an Amendment of FASB Statements No. 66 and 67" ("SFAS No. 152"). This Statement amends FASB Statement No. 66, "Accounting for Sales of Real Estate", to reference the financial accounting and reporting guidance for real estate time-sharing transactions that is provided in AICPA Statement of Position (SOP) 04-2, "Accounting for Real Estate Time-Sharing Transactions". This Statement also amends FASB Statement No. 67, "Accounting for Costs and Initial Rental Operations of Real Estate Projects", to state that the guidance for (a) incidental operations and (b) costs incurred to sell real estate projects do not apply to real estate time-sharing transactions. The accounting for those operations and costs is subject to the guidance in SOP 04-2. This Statement is effective for financial statements for fiscal years beginning after June 15, 2005, with earlier application encouraged. The Company has evaluated the impact of the adoption of SFAS No. 152 and does not believe the impact will be significant to the Company's overall results of operations or financial position, as the Company does not engage in these sorts of transactions. 10 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) NOTES TO FINANCIAL STATEMENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- (2) RECENT ACCOUNTING PRONOUNCEMENTS (CONTINUED): In December 2004, the FASB issued SFAS No. 153, "Exchanges of Nonmonetary Assets", an amendment of AOB Opinion No. 29. This statement was the result of a joint effort by the FASB and the International Accounting Standards Board ("IASB") to improve financial reporting by eliminating certain narrow differences between their existing standards. One such difference was the exception from fair value measurement in AOB Opinion No. 29, "Accounting for Nonmonetary Transactions", for nonmonetary exchanges of similar productive assets. SFAS No. 153 replaces this exception with a general exception from fair value measurement for exchanges of nonmonetary assets that do not have commercial substance. A nonmonetary exchange has commercial substance if the future cash flows of the entity are expected to change significantly as a result of the exchange. This statement shall be applied prospectively and is effective for nonmonetary asset exchanges occurring in fiscal periods beginning after June 15, 2005. The Company does not believe that the adoption of SFAS No. 153 will have a material effect on its financial statements. In November 2004, the FASB issued SFAS No. 151, "Inventory Costs - an Amendment of ARB No. 42, Chapter 4". The amendments made by Statement No. 151 clarify that abnormal amounts of idle facility expense, freight, handling costs, and wasted materials (spoilage) should be recognized as current-period charges and require the allocation of fixed production overheads to inventory based on the normal capacity of the production facilities. The guidance is effective for inventory costs incurred during fiscal years beginning after June 15, 2005. Earlier application is permitted for inventory costs incurred during fiscal years beginning after November 23, 2004. The Company has evaluated the impact of the adoption of SFAS No. 151 and does not believe the impact will be significant to the Company's overall results of operations or financial position. In March 2004, the Emerging Issues Task Force ("EITF") reached a consensus on recognition and measurement guidance previously discussed under EITF No. 03-01, "The Meaning of Other-Than-Temporary Impairment and Its Application To Certain Investments". The consensus clarified the meaning of other-than-temporary impairment and its application to debt and equity investments accounted for under SFAS No. 115 and other investments accounted for under the cost method. The recognition and measurement guidance for which the consensus was reached in March 2004 is to be applied to other-than-temporary impairment evaluations in reporting periods beginning after June 15, 2004. In September 2004, the FASB issued a final FASB Staff Position that delays the effective date for the measurement and recognition guidance for all investments within the scope of EITF No 03-01. The consensus reached in March 2004 also provided for certain disclosure requirements associated with cost method investments that were effective for fiscal years ending after June 15, 2004. The Company will evaluate the effect of adopting the recognition and measurement guidance when the final consensus is reached. In December 2003, the FASB issued Statement of Financial Accounting Standards (FAS) No. 132 (Revised 2003) "Employers' Disclosures about Pensions and Other Postretirement Benefits". This standard replaces FAS-132 of the same title, which was previously issued in February 1998. The revised FAS-132 was issued in response to concerns expressed by 11 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) NOTES TO FINANCIAL STATEMENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- (2) RECENT ACCOUNTING PRONOUNCEMENTS (CONTINUED): financial statement users about their need for more transparency of pension information. The revised standard increases the existing GAAP disclosures for defined benefit pension plans and other defined benefit postretirement plans. However, it does not change the measurement or recognition of those plans as required under FAS-87, "Employers' Accounting for Pensions", FAS-88, "Employers' Accounting for Settlements and Curtailments of Defined Benefit Pension Plans and for Termination Benefits", and FAS-106, "Employers' Accounting for Postretirement Benefits Other Than Pensions". Specifically, the revised standard requires companies to provide additional disclosures about pension plan assets, benefit obligations, cash flows, and benefit costs of defined benefit pension plans and other defined benefit postretirement plans. Also, for the first time, companies are required to provide a breakdown of plan assets by category, such as debt, equity, and real estate, and to provide certain expected rates of return and target allocation percentages for these asset categories. The revised FAS-132 is effective for financial statements with fiscal years ending after December 15, 2003, and for interim periods beginning after December 15, 2003. The adoption of this Statement did not have a material impact on the Company's financial position, results of operations, or cash flows. In December 2003, the Securities and Exchange Commission ("SEC") issued Staff Accounting Bulletin ("SAB") No. 104, "Revenue Recognition". SAB No. 104 supersedes SAB No. 101, "Revenue Recognition in Financial Statements". SAB 104's primary purpose is to rescind accounting guidance contained in SAB No. 101 related to multiple element revenue arrangements, superseded as a result of the issuance of EITF 00-21, "Accounting for Revenue Arrangements with Multiple Deliverables". Additionally, SAB No. 104 rescinds the SEC's Revenue Recognition in Financial Statements Frequently Asked Questions and Answers ("the FAQ") issued with SAB No. 101 that had been codified in SEC Topic 13, Revenue Recognition. Selected portions of the FAQ have been incorporated into SAB No. 104. While the wording of SAB No. 104 has changed to reflect the issuance of EITF 00-21, the revenue recognition principles of SAB No. 101 remain largely unchanged by the issuance of SAB No. 104, which was effective upon issuance. The adoption of SAB No. 104 did not impact the financial statements. In May 2003, the FASB issued SFAS No. 150, "Accounting for Certain Financial Instruments with Characteristics of both Liabilities and Equity". SFAS No. 150 establishes standards for how an issuer classifies and measures certain financial instruments with characteristics of both liabilities and equity. It requires that issuers classify a financial instrument that is within its scope as a liability (or an asset in some circumstances). With certain exceptions, this Statement is effective for financial instruments entered into or modified after May 31, 2003, and otherwise is effective at the beginning of the first interim period beginning after June 15, 2003. The adoption of this Statement did not have a material impact on the Company's financial position, results of operations, or cash flows. In April 2003, the FASB issued SFAS No. 149, "Amendment of Statement 133 on Derivative Instruments and Hedging Activities". SFAS No. 149 amends and clarifies financial accounting and reporting of derivative instruments, including certain derivative instruments embedded in other contracts (collectively referred to as derivatives) and for hedging activities under SFAS No. 133, "Accounting for Derivative Instruments and Hedging Activities". This Statement is effective for contracts entered into or modified after June 30, 2003, except for certain hedging 12 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) NOTES TO FINANCIAL STATEMENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- (2) RECENT ACCOUNTING PRONOUNCEMENTS (CONTINUED): relationships designated after June 30, 2003. The adoption of this Statement did not have a material impact on the Company's financial position, results of operations, or cash flows. In January 2003, the FASB issued FASB Interpretation No. ("FIN") 46 (revised December 2003 by FIN 46R), CONSOLIDATION OF VARIABLE INTEREST ENTITIES, which addresses how a business enterprise should evaluate whether it has a controlling financial interest in an entity through means other than voting rights and, accordingly, should consolidate the entity. The Company will be required to apply FIN 46R to variable interests in variable interest entities ("VIEs") created after December 31, 2004. For variable interests in VIEs that must be consolidated under FIN 46R that were created before January 1, 2004, the assets, liabilities, and noncontrolling interests of the VIE initially would be measured at their carrying amounts with any difference between the net amount added to the balance sheet and any previously recognized interest being recognized as the cumulative effect of an accounting change. If determining the carrying amounts is not practicable, fair value at the date FIN 46R first applies may be used to measure the assets, liability, and noncontrolling interest of the VIE. The Company believes the adoption of FIN 46R will not have a material impact to its financial position, results of operations, or cash flows as the Company does not have any VIEs. (3) MAJOR CUSTOMERS: During the year ended December 31, 2003, one nonrelated customer accounted for 100% of the revenue. There were no major customers for December 31, 2004. (4) PROPERTY AND EQUIPMENT: A summary is as follows: December 31, December 31, 2004 2003 ------------ ------------ Furniture and fixtures $14,770 $ 5,884 Less accumulated depreciation (4,911) (3,089) ------- ------- $ 9,859 $ 2,795 ======= ======= 13 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) NOTES TO FINANCIAL STATEMENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- (5) DEFERRED LOAN COSTS: A summary is as follows: December 31, December 31, 2004 2003 ------------ ------------ Loan Costs $ 87,401 $ -- Less accumulated amortization (21,850) -- -------- -------- $ 65,551 $ -- ======== ======== (6) PENSION PLAN: During the year ended December 31, 2004, the Company has adopted a simplified Employee Pension Program where the Company, on a discretionary basis, can contribute up 25% of eligible participant salaries up to an annual maximum in accordance with IRS regulations. The Company made a $ 52,000 contribution for the year ending December 31, 2004. (7) CONVERTIBLE NOTES PAYABLE: The Company issued $500,000 of convertible notes payable on September 30, 2004. The notes are secured and bear interest at 6% per annum. Principal and interest are due on September 30, 2005. The notes are convertible into common stock at a conversion price equal to $0.3596 per share of stock at the option of the holder prior to the due date. There are registration rights attached to the underlying shares of the convertible feature. It has been determined that there is no beneficial element of the conversion feature after the allocation of the warrants, discussed below, as set forth in EITF 00-27, as the conversion feature approximates the fair value of the shares on the date they were issued. Additionally, the note holders received 556,123 warrants to purchase common stock in connection with the issuance of convertible notes. The warrants are exercisable at $0.5394 per share of stock and are for a term of five years. The fair value attributable to these warrants was $0 as of September 30, 2004. The fair value was determined using Black-Scholes option-pricing method, a 3.50% risk-free interest rate, and .0% expected volatility for a nonpublic company. 14 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) NOTES TO FINANCIAL STATEMENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- (8) INCOME TAXES: The provision for income taxes consists of the following: December 31, December 31, 2004 2003 ------------ ------------ Current: Federal $ -- $ -- State (800) (800) Deferred taxes -- -- --------- --------- Income tax provision $ (800) $ (800) ========= ========= The difference between the provision for income taxes and the U.S. statutory income tax rate of 34% is as follows: December 31, December 31, 2004 2003 ------------ ------------ Tax benefit computed at 34% $(182,900) $ (18,900) Permanent tax difference on option accounting 10,000 -- Valuation allowance against net operating losses 173,700 19,700 --------- --------- Income tax expense $ 800 $ 800 ========= ========= Deferred income tax assets (liabilities) on the balance sheet are as follows: December 31, December 31, 2004 2003 ------------ ------------ Net current deferred tax assets- Net operating losses $ 193,400 $ 19,700 Valuation allowance (193,400) (19,700) --------- --------- Net deferred tax assets (liabilities) $ -- $ -- ========= ========= During the year ending December 31, 2004, the Company increased its valuation allowance $173,700 against deferred income taxes. The valuation allowance reduces deferred tax assets to an amount that represents management's best estimates of the amount of such deferred income taxes, that more likely than not, will be realized. Realization of the deferred tax assets is dependent on sufficient future taxable income during the period that temporary differences and carryforwards are expected to be available to reduce taxable income. 15 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) NOTES TO FINANCIAL STATEMENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- (8) INCOME TAXES (CONTINUED): At December 31, 2004, the Company had approximately $600,000 of net operating losses (NOL) carryforwards to offset against future income. If 50% or more of ownership of the Company changes hands in the future, the NOL may be subject to limitation on how much of the NOL could be utilized in any given year. The NOL will expire in the year 2023 for federal purposes. (9) STOCKHOLDERS' DEFICIT: COMMON STOCK: The Company was incorporated in the State of California on February 1, 2002. The Company was originally authorized to issue 25,000 shares of stock. On March 3, 2004, a new corporation was incorporated in Delaware with a par value of $ .001 per share with 20,000,000 shares authorized. On June 17, 2004, the two corporations were merged in a tax-free reorganization with the Delaware corporation being the surviving entity. This was treated as a recapitalization for financial statement purposes. Accordingly, the outstanding stock from inception is shown at the recapitalized amounts. On March 4, 2005, the Company increased its authorized stock to 24,000,000, effective with the increase in authorized stock the Company also declared a 1.2-for-1 stock split. Accordingly these financial statements retrospectively reflect these changes. Holders of the common stock are entitled to one vote per share. The majority shareholders (97%) are subject to the Company's right of first refusal should any stockholders decide to sell shares unless a public market exists for the Company's common stock, the Company is dissolved, or more than 65% of the outstanding stock is sold. STOCK OPTIONS: In 2004 the Company adopted the Stock Option Plan (the Plan) and reserved 3,000,000 shares of common stock for issuance under the Plan. Under the Plan, incentive options to purchase the Company's common stock may be granted to employees at prices not lower than fair market value at the date of the grant as determined by the Board of Directors. Nonstatutory options (options that do not qualify as incentive options) may be granted to employees and consultants at prices no lower that 85% of fair market value at the date of grant as determined by the Board of Directors. In addition, incentive or nonstatutory options may be granted to persons owning more than 10% of the voting power of all classes of stock at prices no lower than 110% of the fair market value at the date of grant as determined by options (no longer than ten years from the date of the grant, five years in certain instances). Options granted generally vest at a rate between 25% to 50% per year. 16 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) NOTES TO FINANCIAL STATEMENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- (9) STOCKHOLDERS' DEFICIT (CONTINUED): STOCK OPTIONS (CONTINUED): Activity under the plan is as follows: Weighted Shares Average Available Number Exercise Aggregate For Grant of Shares Price Price ---------- ---------- ---------- ---------- Plan Instituted 3,000,000 -- -- -- Options Granted (1,729,800) 1,729,800 $ .5388 932,016 Options Exercised -- -- -- -- Options Expired 164,546 (164,546) .5388 (88,658) ---------- ---------- ---------- ---------- Balance at December 31, 2004 1,434,746 1,565,254 $ .5388 $ 843,358 ========== ========== ========== ========== During the year ended December 31, 2004, the Company issued 1,069,800 options to purchase common stock to its employees and directors. The fair value of these options was $0 upon issuance. During the years ended December 31, 2004, the Company issued 660,000 options to purchase common stock for services rendered by nonemployees. The fair value of these options was $0 upon issuance. The fair value of nonemployee options issued was determined using the Black-Scholes method based on assumed volatility of 0.0%, an option life equal to ten years, a risk-free interest rate of 5.5% based on the grant date and the term of the option and assuming no dividends. Total options under the Plan at December 31, 2004, comprised the following: Weighted Number Average Number Option Outstanding Remaining Exercisable Exercise as of Contractual as of Price 12/31/04 Life (Years) 12/31/04 -------- ----------- ------------ -------------- $ .292 905,254 9.50 599,254 .833 660,000 9.33 165,000 --------- --------- 1,565,254 764,254 ========= ========= 17 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) NOTES TO FINANCIAL STATEMENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- (9) STOCKHOLDERS' DEFICIT (CONTINUED): STOCK OPTIONS (CONTINUED): In addition, the Company issued 103,212 options during the year ended December 31, 2004, to a former employee in a nonplan option grant. The fair value is computed on the date of the grant using the intrinsic value method in accordance with APB Opinion No. 25, "Accounting for Stock Issued to Employees"; $30,000 was recorded as a result of this computation. WARRANTS: The following warrants are each exercisable into shares of common stock: Average Weighted Number of Exercise Aggregate Shares Price Price --------- -------- --------- Balance at December 31, 2003 -- $ -- $ -- Warrants Granted 556,123 .53941 299,982 Warrants Exercised -- -- -- Warrants Canceled -- -- -- Warrants Expired -- -- -- -------- ------- -------- Balance at December 31, 2004 556,123 $.53941 $299,982 ======== ======= ======== All warrants issued during the year were issued in conjunction with convertible debt issuance (see Note 7), and all warrants will expire during the fiscal year ending December 31, 2005. SHARES RESERVED FOR FUTURE ISSUANCE: The Company has reserved shares of common stock for future issuance at December 31, 2004: Stock Option Plan 1,565,254 Stock Option Outside of Plan 103,212 Stock Warrants 556,123 --------- Total 2,224,589 ========= 18 BIONOVO BIOPHARMACEUTICALS, INC. (FORMERLY BIONOVO, INC.) (A DEVELOPMENT STAGE COMPANY) NOTES TO FINANCIAL STATEMENTS YEARS ENDED DECEMBER 31, 2004 AND 2003 - -------------------------------------------------------------------------------- (10) LICENSE AGREEMENT: In 2003, the Company entered into a licensing and technology transfer agreement with a Taiwan biotech corporation wherein the rights to certain technology restricted to a certain geographic region were transferred to the Taiwan corporation for a period of 10 years, which will automatically renew for periods of 3 years, unless a 12-month written notice is given by either party to the agreement. The license agreement was for a one-time fee of $150,000 and future royalties based on 10% of future sales. Additional fees may be earned by the Company in the future for additional clinical work. (11) CONTINGENCIES AND COMMITMENTS: The Company entered into a consulting agreement with Duncan Capital, LLC to provide certain financial consulting services. The agreement provides that Duncan Capital, LLC is to receive compensation in the form of a cash fee of $100,000 plus warrants exercisable at a price of $0.010 equal to 3.675% of the fully-diluted capital stock of the Company after a successful reverse merger. In addition, Duncan Capital, LLC will receive compensation of warrants exercisable at $0.6473 per share of stock in an amount equal to 10% of the aggregate number of fully- diluted shares of common stock converted by the convertible note payable holders. The term of the warrants will be for five years. Duncan Capital, LLC will receive 10% of the aggregate number of fully-diluted shares of common stock for any debt financing that it arranges. The strike price of the warrants will be equal to the strike price negotiated with the debt holders. (12) SUBSEQUENT EVENTS: During March 2005, the Company increased the shares available under the Stock Option Plan from 3,000,000 shares to 3,600,000. During April 2005, the Company closed a private placement memorandum wherein approximately $8,095,500 was raised for approximately 16,191,000 shares of common stock and approximately 4,047,500 warrants to purchase shares of common stock to investors and 3,688,730 warrants to others. On April 6, 2005, the Company completed a reverse merger with Lighten Up Enterprises International, Inc., a public company, whereby a newly- created, wholly-owned subsidiary of the public company merged with and into the Company in a tax free exchange, with the Company surviving. Following the reverse merger, the Company is a wholly-owned subsidiary of the public company. The stock of the public company continues to be quoted on the OTC Bulletin Board under the symbol LTUP.OB. The stockholders of the Company received stock of the public company representing approximately 90.4% of the common stock outstanding immediately after the reverse merger. Also, during April 2005, the convertible debt holders elected to convert $450,000 of the convertible debt to common stock pursuant to the terms of the note. Subsequent to year end, the Company executed an agreement with a university to conduct clinical coordinating services as part of a clinical trial of certain of its drugs. The cost of the service is approximately $800,000. The services will commence only when the Company provides the neccesary materials to start the clinical trial, which is expected in Fall of 2005. Payments will be made quarterly, as the clinical trial progresses. As of June 28, 2005, the Company, Bionovo, Inc., changed its name to Bionovo Biopharmaceuticals, Inc. 19 BIONOVO, INC. (FORMERLY LIGHTEN UP ENTERPRISES INTERNATIONAL, INC.) AND SUBSIDIARIES PRO FORMA COMBINED FINANCIAL STATEMENTS The following unaudited pro forma condensed combined balance sheet aggregates the balance sheet of Bionovo, Inc. (formerly Lighten Up Enterprises International, Inc.) as of December 31, 2004, and the balance sheet of Bionovo Biopharmaceuticals, Inc. (formerly Bionovo, Inc.), a Delaware corporation as of December 31, 2004. The following unaudited pro forma condensed combined statement of operations aggregates the statement of operations of Bionovo for the year ended December 31, 2004, and the statement of operations of Bionovo Biopharmaceuticals for the year ended December 31, 2004. The following unaudited pro forma condensed combined balance sheet and statement of operations were prepared giving effect to a transaction completed on April 6, 2005, wherein a subsidiary of Bionovo, LTUP Acquisition Corp., merged with and into Bionovo Biopharmaceuticals, with Bionovo Biopharmaceuticals surviving. On April 6, 2005, we completed a so-called "reverse merger" transaction, in which we caused LTUP Acquisition Corp., a Delaware corporation and our newly-created, wholly-owned subsidiary, to be merged with and into Bionovo Biopharmaceuticals, Inc. (formerly Bionovo, Inc.), a Delaware corporation. Bionovo Biopharmaceuticals is a drug discovery and development company focusing on cancer and women's health. As a result of the merger, Bionovo Biopharmaceuticals became our wholly-owned subsidiary, with Bionovo Biopharmaceutical's former security holders acquiring a majority of the outstanding shares of our common stock, par value $0.0001 per share. The reverse merger was consummated under Delaware law and pursuant to an Agreement of Merger and Plan of Reorganization, dated April 6, 2005 (the "Merger Agreement"). Immediately prior to the closing of the reverse merger, Bionovo Biopharmaceuticals completed the closing of a private offering of Units comprised of its common stock and warrants to purchase its common stock to new investors. Bionovo Biopharmaceuticals received gross proceeds of $8,095,500 at the closing of the private offering. Under the Merger Agreement, at closing, we issued 37,842,448 shares of our common stock to the former security holders of Bionovo Biopharmaceuticals, representing approximately 90.4% of our outstanding common stock following the merger, in exchange for 100% of the outstanding capital stock of Bionovo Biopharmaceuticals, subject to appraisal rights of former Bionovo Biopharmaceuticals stockholders. In addition, all warrants issued by Bionovo Biopharmaceuticals to purchase shares of Bionovo Biopharmaceuticals common stock outstanding immediately prior to the merger were amended to become warrants to purchase common stock of Bionovo on the same terms and conditions as those warrants issued by Bionovo Biopharmaceuticals, including the number of shares issuable upon the exercise of the warrants. Immediately prior to the closing of the merger, all outstanding Bionovo Biopharmaceuticals warrants were exercisable for 6,445,394 shares of Bionovo Biopharmaceuticals common stock, which included the warrants issued in Bionovo Biopharmaceuticals private offering. At the closing of the merger, these warrants were amended to become warrants to purchase the same number of shares of Bionovo common stock. Further, all stock options issued by Bionovo Biopharmaceuticals under its Stock Incentive Plan or otherwise to purchase shares of Bionovo Biopharmaceuticals common stock outstanding immediately prior to the merger were amended to become stock options to purchase common stock of Bionovo on the same terms and conditions as those stock options issued by Bionovo Biopharmaceuticals, including the number of shares issuable upon the exercise of such stock options. Immediately prior to the closing of the merger, all outstanding Bionovo Biopharmaceuticals stock options were exercisable for 1,740,465 shares of Bionovo Biopharmaceuticals common stock. At the closing of the merger, these stock options were amended to become stock options to purchase the same number of shares of Bionovo common stock. We did not have any stock options outstanding as of immediately prior to the closing of the merger. The following pro forma condensed balance sheet and statement of operations uses the assumptions as described in the notes and the historical financial information available at December 31, 2004. The financial statements of both Bionovo and Bionovo Biopharmaceuticals at December 31, 2004 are audited. The unaudited pro forma condensed combined balance sheet and statement of operations should be read in conjunction with the separate financial statements and related notes thereto of Bionovo and Bionovo Biopharmaceuticals. The unaudited pro forma condensed combined balance sheet and statement of operations are not necessarily indicative of the condensed combined balance sheet and statement of operations which might have existed for the periods indicated or the results of operations as they may appear now or in the future. BIONOVO, INC. (FORMERLY LIGHTEN UP ENTERPRISES INTERNATIONAL, INC.) AND SUBSIDIARIES PRO FORMA CONDENSED COMBINED BALANCE SHEETS As of December 31, 2004 (Unaudited) Bionovo Bionovo Biopharmaceuticals ADJUSTMENTS COMBINED --------------------------- ----------- --------- ASSETS CURRENT ASSETS: Cash and cash equivalents 37 $ 196,013 -- 196,050 Due from officers -- 1,796 -- 1,796 Prepaid expenses and other current assets -- -- -- -- ------------------------- --------- --------- Total current assets 37 197,809 -- 197,846 PROPERTY AND EQUIPMENT, net of accumulated depreciation -- 9,859 -- 9,859 OTHER ASSETS: Deferred loan costs net of accumulated amortization -- 65,551 -- 65,551 Patent costs -- 11,264 -- 11,264 ------------------------- --------- --------- $ 37 $ 284,483 $ -- $ 284,520 ========================= ========= ========= LIABILITIES AND STOCKHOLDERS' DEFICIT CURRENT LIABILITIES: Accounts payable and accrued expenses 131,169 $ 163,613 (131,169)(1) 163,613 Accrued pension payable -- 52,000 -- 52,000 Deferred revenue -- 15,000 -- 15,000 Convertible notes payable -- 500,000 -- 500,000 ------------------------- --------- --------- Total current liabilities 131,169 730,613 (131,169) 730,613 ------------------------- --------- --------- DEFERRED REVENUE 0 117,500 -- 117,500 ------------------------- --------- LONG TERM LIABILITIES Accrued interest - related party 41,152 -- (41,152) -- ------------------------- --------- --------- STOCKHOLDERS' DEFICIT: Common stock, $0.001 par value: Additional paid-in capital 2,504 24,400 (2,104)(2) 24,800 Accumulated deficit 221,403 5,600 (221,766)(2) 5,237 (396,191) (593,630) 396,191 (593,630) ------------------------- --------- --------- Total stockholders' deficit (172,284) (563,630) 172,321 (563,593) ------------------------- --------- --------- $ 37 $ 284,483 -- 284,520 ========================= ========= ========= (1) Bionovo related party forgave loans. (2) Bionovo shareholders surrendered 21,040,000 shares. SEE ACCOMPANYING NOTES TO UNAUDITED PRO FORMA CONDENSED COMBINED FINANCIAL STATEMENTS Unaudited Pro Forma Condensed Combined Financial Statements of Bionovo, Inc. (formerly Lighten Up Enterprises International, Inc.) and Subsidiaries: The following unaudited pro forma condensed combined financial statements give effect to the acquisition of Bionovo Biopharmaceuticals by the Company using the purchase method of accounting and include the pro forma adjustments described in the accompanying notes. The following unaudited pro forma condensed combined balance sheet as of December 31, 2004, and combined statements of operations for the year ended December 31, 2004 are based on the historical financial statements of Bionovo and Bionovo Biopharmaceuticals after giving the effect to the acquisition of Bionovo Biopharmaceuticals under the purchase method of accounting. BASIS OF PRESENTATION The unaudited pro forma condensed combined financial statements as of December 31, 2004 record the acquisition transaction as if the acquisition had taken place on January 1, 2004. The unaudited pro forma condensed combined balance sheet is presented to give effect to the acquisition as if it occurred on December 31, 2004, and combines the balance sheets of Bionovo and Bionovo Biopharmaceuticals as of that date. The pro forma information does not purport to be indicative of the results that would have been reported if the above transactions had been in effect for the periods presented or which may result in the future. BIONOVO, INC. (FORMERLY LIGHTEN UP ENTERPRISES INTERNATIONAL, INC.) AND SUBSIDIARIES PRO FORMA CONDENSED COMBINED STATEMENTS OF OPERATIONS YEAR ENDED DECEMBER 31, 2004 (Unaudited) Bionovo Bionovo Biopharmaceuticals ADJUSTMENTS COMBINED -------------------------------- ----------- ----------- REVENUE $ 4,087 $ 45,240 (4,087) 45,240 COST OF SALES -- -- -- -- -------------------------------- ----------- ----------- GROSS PROFIT 4,087 45,240 (4,087) 45,240 -------------------------------- ----------- ----------- OPERATING EXPENSES: Research and development -- 275,600 -- 275,600 General and administrative 31,077 277,433 (21,077) 287,433 Sales and marketing 39,548 500 (39,548) 500 -------------------------------- ----------- ----------- Total operating expenses 70,625 553,533 (60,625) 563,533 -------------------------------- ----------- ----------- LOSS FROM OPERATIONS (66,538) (508,293) 56,538 (518,293) OTHER INCOME (EXPENSE): Forgiveness of loan payable -- -- Interest expense (2,061) (28,855) 2,061 (28,855) -------------------------------- ----------- ----------- Total other income (2,061) (28,855) 2,061 (28,855) LOSS BEFORE INCOME TAXES (68,599) (537,148) 58,599 (547,148) PROVISION FOR INCOME TAXES -- (800) -- (800) -------------------------------- ----------- ----------- NET LOSS $ (68,599) $ (537,948) $ 58,599 $ (547,948) ================================ =========== =========== NET LOSS PER SHARE $ (0.00) $ (0.03) $ 0.00 $ (0.01) ================================ =========== =========== WEIGHTED AVERAGE SHARES OUTSTANDING 25,040,000 20,400,000 21,040,000 24,400,000 ================================ =========== =========== SEE ACCOMPANYING NOTES TO UNAUDITED PRO FORMA CONDENSED COMBINED FINANCIAL STATEMENTS SUMMARY OF TRANSACTION On April 6, 2005, we completed a so-called "reverse merger" transaction, in which we caused LTUP Acquisition Corp., a Delaware corporation and our newly-created, wholly-owned subsidiary, to be merged with and into Bionovo Biopharmaceuticals, Inc. (formerly Bionovo, Inc.), a Delaware corporation. Bionovo Biopharmaceuticals is a drug discovery and development company focusing on cancer and women's health. As a result of the merger, Bionovo Biopharmaceuticals became our wholly-owned subsidiary, with Bionovo Biopharmaceuticals' former security holders acquiring a majority of the outstanding shares of our common stock, par value $0.0001 per share. The reverse merger was consummated under Delaware law and pursuant to an Agreement of Merger and Plan of Reorganization, dated April 6, 2005. Pursuant to the Merger Agreement, at closing, stockholders of Bionovo Biopharmaceuticals received one share of our common stock for each share of Bionovo Biopharmaceuticals common stock in the merger. As a result, at closing we issued 37,842,448 shares of our common stock to the former stockholders of Bionovo Biopharmaceuticals, representing approximately 90.4% of our outstanding common stock following the merger, in exchange for 100% of the outstanding capital stock of Bionovo Biopharmaceuticals. The consideration issued in the merger was determined as a result of arm's-length negotiations between the parties. As of April 6, 2005, our board of directors also approved a change in our certifying accountant. Prior to effecting the change of our certifying accountant, the board of directors determined to retain our current accountants in connection with the preparation of our Form 10-QSB for the quarter ended March 31, 2005. The shares of our common stock issued to former holders of Bionovo Biopharmaceuticals common stock in connection with the merger, including the investors in the Bionovo Biopharmaceuticals private offering, and the shares of our common stock issued in our subsequent private offering, were not registered under the Securities Act of 1933 in reliance upon the exemption from registration provided by Section 4(2) of that Act and Regulation D promulgated under that section, which exempts transactions by an issuer not involving any public offering. These shares may not be offered or sold in the United States absent registration or an applicable exemption from the registration requirements. Certificates representing these shares contain a legend stating the same. PRO FORMA ADJUSTMENTS The pro forma combined balance sheet as of December 31, 2004 gives effect to the forgiveness of a liability of $131,169, and accrued interest of $41,152, as the related party that provided the loan agreed to forgive the loan and all accrued interest pursuant to the reverse merger. The pro forma condensed combined statements of operations for the year ended December 31, 2004, gives effect to the disposal of the cook book business. Additionally, shareholders of 21,040,000 shares surrendered shares to treasury pursuant to the reverse merger. PRO FORMA NET LOSS PER SHARE The pro forma basis and dilutive net loss per share are based on the weighted average number of shares of pro forma Bionovo's common stock as if the shares issued to acquire Bionovo Biopharmaceuticals had taken place at the beginning of the year. Dilutive shares are not included in the computation of pro forma dilutive net loss per share as their effect would be anti-dilutive. EXHIBIT INDEX EXHIBIT NO. DESCRIPTION - ----------- ----------- 10.11 Licensing & Technology Transfer Agreement, dated November 6, 2003, with United Biotech Corporation (certain terms of this agreement have been omitted and are subject to a request for confidential treatment with the SEC)