EXHIBIT 21.1 LIST OF SUBSIDIARIES - -------------------------------------------------------------------------------- Name State or Other Jurisdiction of Incorporation - -------------------------------------------------------------------------------- Signal Pharmaceuticals, Inc. California Anthrogenesis Corp. New Jersey Celgene International, Inc. Delaware Celgene International SARL Switzerland Celgene Luxembourg Finance Company SARL Luxembourg Celgene UK Holdings, Limited United Kingdom Celgene UK Manufacturing, Limited United Kingdom Celgene UK Manufacturing II, Limited United Kingdom Celgene UK Manufacturing III, Limited United Kingdom Celgene Edinburgh Finance United Kingdom Celgene Europe Ltd. United Kingdom Celgene International Holdings Corporation Delaware Celgene UK Distribution Limited United Kingdom Celgene Limited United Kingdom Celgene Srl Italy Celgene Sociedades por quotas Portugal Celgene Puerto Rico Distribution LLC Puerto Rico Celgene Spain Division, S.L. Spain Celgene Germany Distribution GmbH Germany Celgene Sarl France Celgene Limited Ireland Celgene Investment Company, LLC Delaware Celgene Financing Company, LLC Delaware Celgene Canadian Finance Company LP Canada 4319257 Canada, Inc. Canada 4319265 Canada, Inc. Canada Celgene (Partnership) Canada Celgene KK Japan Celgene Handels Gmbh Austria Celgene AB Sweden Celgene GmbH Switzerland Celgene BVBA Belgium Celgene Pty Australia Celgene BV Netherlands Celgene Netherlands BV Netherlands Celgene Chemicals Sarl Switzerland Celgene Logistics Sarl Switzerland Celgene Switzerland SA Switzerland Morris Avenue Investment LLC New Jersey