UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                   FORM 12B-25

                           NOTIFICATION OF LATE FILING

(Check one):   [X] Form 10-K [ ] Form 20-F [ ] Form 11-K [ ] Form 10-Q
               [ ] Form 10-D [ ] Form N-SAR [ ] Form N-CSR
               For Period Ended: DECEMBER 31, 2007
               [ ] Transition Report on Form 10-K
               [ ] Transition Report on Form 20-F
               [ ] Transition Report on Form 11-K
               [ ] Transition Report on Form 10-Q
               [ ] Transition Report on Form N-SAR
               For the Transition Period Ended:______________________________

If the notification relates to a portion of the filing checked above, identify
the Item(s) to which the notification relates:
- -------------------------------------------------------------------------------

PART I -- REGISTRANT INFORMATION

TETRAGENEX PHARMACEUTICALS, INC.
- -------------------------------------------------------------------------------
Full Name of Registrant

- -------------------------------------------------------------------------------
Former Name if Applicable

1 MAYNARD DRIVE, SUITE 105
- -------------------------------------------------------------------------------
Address of Principal Executive Office (Street and Number)

PARK RIDGE, NEW JERSEY 07656
- -------------------------------------------------------------------------------
City, State and Zip Code

PART II-- RULES 12B-25(b) AND (c)

If the subject report could not be filed without unreasonable effort or expense
and the registrant seeks relief pursuant to Rule 12b-25(b), the following should
be completed. (Check box if appropriate)

[X]  (a)  The reason  described  in  reasonable  detail in Part III of this form
          could not be eliminated without unreasonable effort or expense;

[X]  (b)  The subject annual report,  semi-annual  report,  transition report on
          Form 10-K,  Form 20-F, Form 11-K, Form D, Form N-SAR or Form N-CSR, or
          portion thereof, will be filed on or before the fifteenth calendar day
          following the prescribed due date; or the subject  quarterly report or
          transition report on Form 10-Q or subject  distribution report on Form
          10-D,  or  portion  thereof,  will be filed  on or  before  the  fifth
          calendar day following the prescribed due date; and

[ ]  (c)  The accountant's statement or other exhibit required by Rule l2b-25(c)
          has been attached if applicable.


                    PERSONS WHO ARE TO RESPOND TO THE COLLECTION OF INFORMATION
                    CONTAINED IN THIS FORM ARE NOT REQUIRED TO RESPOND  UNLESS
SEC 1344 (05-06)    THE FORM DISPLAYS A CURRENTLY VALID OMB CONTROL NUMBER.





                              PART III -- NARRATIVE

State below in reasonable  detail why Forms 10-K, 20-F, 11-K, l0-Q, 10-D, N-SAR,
N-CSR, or the transition  report or portion  thereof,  could not be filed within
the prescribed time period.

Despite  diligent  efforts,  the work necessary for Tetragenex  Pharmaceuticals,
Inc.'s (the "Company") preparation of its Annual Report on Form 10-KSB could not
be completed without  unreasonable effort or expense.  Such difficulties prevent
the Company from filing the balance of the report  because such  information  is
integral to the balance of the report.  The Company  fully expects to be able to
file within the additional time allowed by this report.

                          PART IV -- OTHER INFORMATION

(1)  Name  and  telephone  number  of  person  to  contact  in  regard  to  this
     notification

  ARTHUR S. MARCUS, ESQ.               (212)                      752-9700
- -------------------------       ----------------          ---------------------
       (Name)                     (Area Code)                (Telephone Number)

(2)  Have all other periodic  reports  required under Section 13 or 15(d) of the
     Securities Exchange Act of 1934 or Section 30 of the Investment Company Act
     of 1940 during the preceding 12 months or for such shorter  period that the
     registrant  was required to file such  report(s)  been filed ? If answer is
     no, identify report(s).                                      Yes [X] No [ ]

(3)  Is it anticipated that any significant change in results of operations from
     the corresponding  period for the last fiscal year will be reflected by the
     earnings  statements  to be  included  in the  subject  report  or  portion
     thereof?                                                     Yes [ ] No [X]

     If so, attach an explanation of the anticipated  change,  both  narratively
     and quantitatively, and, if appropriate, state the reasons why a reasonable
     estimate of the results cannot be made.

- --------------------------------------------------------------------------------

                        TETRAGENEX PHARMACEUTICALS, INC.
                 -----------------------------------------------
                  (Name of Registrant as Specified in Charter)

has  caused  this  notification  to be signed on its  behalf by the  undersigned
hereunto duly authorized.

Date: April 1, 2008                           By:   /s/ MARTIN F. SCHACKER
                                                    ---------------------------
                                                    Martin F. Schacker
                                                    Co-Chief Executive Officer
                                                    Chairman of the Board

                                       2