EXHIBIT 3.1.2

                           CERTIFICATE OF DESIGNATION

                                       OF

                         CELSION (DELAWARE) CORPORATION

  Certificate              of Designations,  Preferences  Rights and Limitations
                           of SERIES A 10%  CONVERTIBLE  PREFERRED  STOCK  under
                           Section 151 of the Delaware General Corporation Law

                                                   ---------

    Spencer J. Volk and John Mon HEREBY CERTIFY that they are, respectively, the
President and Chief Executive Officer, and the Secretary,  of CELSION (DELAWARE)
CORPORATION (the "Corporation"),  a corporation organized and existing under the
laws of the State of Delaware,  and that,  pursuant to (i)  authority  conferred
upon the Board of Directors by the  Corporations'  Certificate of  Incorporation
and (ii)  Section 151 of the  Delaware  General  Corporation  Law,  the Board of
Directors of the Corporation has duly adopted the following resolution providing
for the issuance of a series of convertible preferred stock, as follows:

        RESOLVED,  that pursuant to authority expressly granted to and vested in
    the Board of Directors by the provisions of the Certificate of Incorporation
    and  Section  151 of the  Delaware  General  Corporation  Law,  the Board of
    Directors hereby creates a series consisting of 7,000 shares of Series A 10%
    Convertible Preferred Stock of the Corporation, and hereby fixes the powers,
    designation,  preferences  and rights of the shares of such Series,  and the
    qualifications,  limitations,  or restrictions thereof (in addition to those
    provisions  set  forth in the  Certificate  of  Incorporation  which  may be
    applicable to the Preferred Stock), as follows:

    FIRST: Pursuant to authority contained in the Corporation's  Charter,  Seven
Thousand  (7,000)  authorized but unissued shares of the  Corporation's  capital
stock,  $.01 par value, have been duly reclassified by the Board of Directors of
the  Corporation as authorized but unissued  shares of Series A 10%  Convertible
Preferred Stock.

    SECOND: A description of the Series A 10% Convertible Preferred Stock and of
the powers,  designation,  preferences  and rights of the shares of such Series,
and the qualifications, limitations, or restrictions thereof, is as follows:

1.     Designation and Par Value.

    The  formal  designation  of the  shares  so  reclassified  by the  Board of
Directors shall be Series A 10% Convertible  Preferred Stock (referred to herein
for convenience as "Series A Preferred Stock" or as "Preferred Shares"). The par
value of Series A Preferred Stock is $.01 per share.

2.     Liquidation Preference and Ranking.

    (a) Upon any voluntary or involuntary liquidation, dissolution or winding up
of the business and affairs of the Corporation, and before the holders of shares
of Common Stock or any other class or series of stock of the Corporation ranking
junior on liquidation  to the Series A Preferred  Stock shall be entitled to any
payment on account of such shares,  the holders of Series A Preferred Stock then
outstanding shall be entitled to receive, as a liquidation preference, an amount
equal to One Thousand  ($1,000.00) dollars per share (the "Original Cost"), plus
any accrued but unpaid  dividends (the Original Cost plus such  dividends  being
referred to as the  "Liquidation  Preference") to which such  shareholders  have
become entitled and which have not theretofore  been paid.  After the holders of
Series A Preferred  Stock shall have  received  such payment of the  Liquidation
Preference  plus  all  accrued  and  unpaid  dividends  in the  course  of  such
liquidation, dissolution or winding up, they shall have no right or claim to any
of the remaining assets of the Corporation.

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    (b) If upon any  liquidation,  dissolution  or winding  up, the  Corporation
shall  have  insufficient  funds to permit  payment  to the  holders of Series A
Preferred Stock then outstanding of the entire amount to which they are entitled
as a Liquidations  Preference  thereunder,  then such funds as are available for
such purpose shall be distributed  among such holders on the basis of the number
of shares of  Series A  Preferred  Stock  held by each such  holder so that,  as
nearly as may be  practicable,  the amount each such holder shall  receive shall
represent the same  proportion of such  available  funds as such holder's  total
holding of shares of Series A Preferred Stock  represents of the total shares of
Series A Preferred Stock at the time outstanding.

    (c) For all purposes under this  Certificate of  Designation,  all shares of
Series A Preferred Stock shall be of equal rank with each other.

3.     Dividends.

    (a) The  holders of Series A  Preferred  Stock shall be entitled to receive,
when,  as and if declared by the Board of Directors of the  Corporation,  out of
capital surplus or earnings at the time legally available therefor, dividends at
the annual  rate of 10% per  share,  payable in  fully-paid  and  non-assessable
shares of Series A Preferred Stock which shall be valued,  for this purpose,  at
an amount equal to the Original  Cost.  Dividends  shall accrue,  whether or not
declared,  unless such  dividends are then  prohibited by the  provisions of the
Delaware   General   Corporation  Law  or  the   Corporation's   Certificate  of
Incorporation.

    (b) Dividends  shall be  cumulative  and shall be payable  semi-annually  on
March 31 and on  September  30 in each  year  commencing  January  1,  2000,  to
stockholders  of record on the  immediately  preceding  March 15th and September
15th, respectively, or such other record date fixed for the purpose by the Board
of Directors. Dividends payable with respect to any shares of Series A Preferred
Stock  for the  initial  dividend  period  and for any  period  less than a full
six-month period shall accrue from the date of issuance of such shares of Series
A Preferred Stock on which such dividends are payable, and shall be computed and
apportioned  on the basis of a 180-day  period  composed  of six 30-day  months.
Holders of Series A Preferred  Stock shall not be entitled to any  dividends  in
excess of the full  dividends  provided  for  herein,  and no interest or sum of
money in lieu of interest  shall be payable in respect of any  dividend  payment
which may be in arrears. No dividends shall be payable on any fractional or full
shares of Series A  Preferred  Stock  which  shall have been  declared,  paid or
distributed as dividends on outstanding Preferred Shares.

4.     No Dividends or Distributions to Junior Securities.

    Except as may be otherwise  provided in this Certificate of Designation,  so
long as any shares of Series A Preferred  Stock are  outstanding,  no  dividends
shall be declared or paid or set aside for  payment,  and no other  distribution
shall be declared or made,  upon any Common Stock of the Corporation or upon any
other  shares of a class or series of stock which is junior in right and ranking
to the Series A Preferred  Stock,  unless all amounts then due to the holders of
Series A Preferred Stock, including the dividends provided for herein, have been
paid.

5.     Voting Rights.

    Except as  otherwise  expressly  provided  herein or as provided by law, the
Series A Preferred Stock shall have no voting rights.  However,  notwithstanding
the  foregoing,  the  written  consent or  affirmative  vote of the holders of a
majority of the outstanding  Series A Preferred Stock is required to approve (i)
any proposed amendment to the Company's  Certificate of Incorporation that would
materially  alter or change the powers,  preferences,  or special  rights of the
Series A  Preferred  Stock so as to affect the holders  adversely,  and (ii) any
plan of merger or consolidation that contains  provisions which, if contained in
a proposed amendment to the Company's  Certificate of Incorporation,  would have
entitled the holders of the Series A Preferred Stock to vote, as a class, on the
issue.

6.     Exchange and Conversion Rights.

    The Preferred  Shares and any fractional  Preferred Shares  (including,  for
such purposes, any shares and fractional shares issued or issuable as dividends)
will be entitled to the following rights of exchange and conversion,  subject to
any limitations and conditions provided in this Certificate of Designation:

                                       5


        (a) (i) If the  Corporation  undertakes  a  public  securities  offering
    (Public  Offering")  registered with the Securities and Exchange  Commission
    ("SEC")  consisting of either (i) equity  securities of the  Corporation  or
    (ii) units ("Units")  comprised of equity  securities of the Corporation and
    of shares of any subsidiary of the Corporation (the securities  and/or Units
    to be sold in such public  offering  being  referred to as "Public  Offering
    Securities"),  and provided that such Public  Offering is consummated by the
    first  anniversary of the date of sale in a private  placement (the "Private
    Placement")  offering of at least  $2,500,000 in aggregate  Original Cost of
    Series A  Preferred  Stock  (such date  being  referred  to as the  "Minimum
    Closing  Date"),  the  Corporation  will  promptly  furnish each holder with
    written  notice of the  Corporation's  filing with the SEC of a registration
    statement concerning the Public Offering. Within 30 days after the giving of
    such  notice  (the  "30-day  Election  Period"),  each such  holder  will be
    required to notify the  Corporation,  by returning a form to be furnished to
    each holder of Preferred Shares by the Corporation, that such holder elects,
    contingent  on  the  consummation  of the  Public  Offering,  either  (1) to
    exchange  100% of the Preferred  Shares then held by such holder  (including
    Preferred  Shares and fractional  Preferred  Shares issued as dividends) for
    such Public Offering  Securities at an exchange price which will be equal to
    70% of the public offering price of the Public Offering  Securities,  or (2)
    to exchange 50% of the Preferred Shares then held by such holder  (including
    Preferred  Shares and  fractional  Shares  issued as  dividends)  for Public
    Offering  Securities at an exchange  price which will be equal to 70% of the
    public offering price of the Public  Offering  Securities and to convert the
    remaining  50% of such  Preferred  Shares into the  Company's  Common  Stock
    ("Common  Stock") at a conversion  price of $0.41 per share of Common Stock,
    as such  price  may be  adjusted  from time to time in  accordance  with the
    provisions  of Section 7 below (as so  adjusted,  the  "Conversion  Price").
    Concurrently  with the consummation of the Public Offering,  each holder who
    has made such an election shall  surrender and deliver to the Corporation or
    to the exchange agent or transfer  agent  designated for such purpose by the
    Corporation,  certificates  for the  Preferred  Shares being  exchanged,  or
    exchanged  and  converted as the case may be, as set forth in such  holder's
    election as described in the immediately preceding sentence. Within five (5)
    business days  thereafter,  the Corporation  will cause to be issued to each
    holder certificates representing the Public Offering Securities being issued
    in exchange for such Preferred Shares, and, as the case may be, certificates
    representing  shares of Common Stock into which 50% of such Preferred Shares
    are being  converted if such holder has so elected in  accordance  with this
    Paragraph (a).

        (ii) In addition,  if the Corporation shall,  within 12 months after the
    Minimum  Closing  Date,  consummate  the  sale  of  any  subsidiary  of  the
    Corporation (or all or  substantially  all of the assets of such subsidiary)
    to a public  company,  or shall complete a merger of such  subsidiary into a
    public company (a "Disposition  Transaction"),  for consideration consisting
    of securities of such public company (the  "Disposition  Securities"),  each
    holder of  Preferred  Shares will be promptly  notified of such  Disposition
    Transaction  in a manner  similar to that  provided  for in the  immediately
    preceding  sub-paragraph,  and will have similar 30-day  Election  Period to
    elect either (1) to exchange 100% of the holder's  Preferred Shares for such
    Disposition Securities at an exchange price equal to 70% of the price of the
    Disposition Securities established in the Disposition Transaction, or (2) to
    exchange 50% of such holder's Preferred Shares for Disposition Securities on
    the same terms and to convert the  remainder of such  Preferred  Shares into
    Common Stock at the Conversion Price. Within 20 days after the expiration of
    the  applicable  30-day  Election  Period,  each holder who had made such an
    election shall  surrender and deliver to the  Corporation or to the exchange
    agent or transfer  agent  designated  for such  purpose by the  Corporation,
    certificates  for the  Preferred  Shares being  exchanged,  or exchanged and
    converted  as the case may be, as set  forth in such  holder's  election  as
    described in the immediately  preceding  sentence.  Within five (5) business
    days  thereafter,  the  Corporation  will cause to be issued to each  holder
    certificates   representing  the  Disposition  Securities  being  issued  in
    exchange for such Preferred  Shares,  and, as the case may be,  certificates
    representing  shares of Common Stock into which 50% of such Preferred Shares
    are being converted if such holder has so elected.

    (b) If any  holder  of  Preferred  Shares  does not  elect  either  exchange
alternative (1) or exchange alternative (2) described in sub-paragraph (a)(i) or
(a)(ii) above, as the case may be, within the applicable 30-day Election Period,
all rights of any such non-electing holder to exchange such Preferred Shares for
Public Offering Securities (or Disposition Securities, as the case may be) or to
convert  such  Preferred  Shares into  Common  Stock at such time or at any time
thereafter shall,  provided the Public Offering or the Disposition  Transaction,
as the case may be, is  consummated  by the  first  anniversary  of the  Minimum
Closing Date, immediately lapse and completely terminate.  The Corporation will,
within a reasonable time  thereafter,  redeem the Preferred  Shares held by such
non-electing  holder  at a  redemption  price  per  share  equal  to 105% of the
Liquidation  Preference,  in accordance  with the provisions of Section 8 below,
except that such  non-electing  holder  shall not be  permitted  to exercise any
right to convert  the  Preferred  Shares  into Common  Stock  granted  under the
provisions of paragraph (c) of this Section 6.

    (c) Other than as set forth in Paragraph  (a) of this Section 6, the holders
of Series A Preferred  Stock will not have any right to convert their  Preferred
Shares prior to the earlier of (i) the first  anniversary of the Minimum Closing
Date or (ii) the  Corporation's  issuance of a  Redemption  Notice as defined in
paragraph  (b) of Section 8. If the Public  Offering is not  consummated  by the
first  anniversary  of the Minimum  Closing  Date,  then, at the election of any
holder of Preferred Shares at any time thereafter,  and subject to the condition
set for in  Paragraph  (d) of this  Section  6,  such  holder  may  convert  his
Preferred Shares (including any whole or fractional Preferred Shares received as
dividends  under the provisions of Section 3) in whole or in part into shares of
the Company's  Common Stock at the  Conversion  Price,  in  accordance  with the
conversion procedure set fort in Paragraph (e) of this Section 6.

                                       6


    (d) In addition,  if at any time subsequent to the first  anniversary of the
Minimum  Closing  Date  (no  sale of  Public  Offering  Securities  having  been
consummated  by such first  anniversary),  the  Corporation  undertakes a public
offering  consisting  of the sale of Common Stock for its own account,  then, at
the specific  election of the  Corporation  and upon notice to me holders of the
Preferred  Stock,  such  holders  may be  required  to convert  their  shares of
Preferred Stock (including any whole or fractional  Preferred Shares received as
dividends  under the provisions of Section 3) into shares of Common Stock at the
Conversion  Price.  Such  election by the  Corporation  may be  exercised by the
giving of notice to holders of Preferred Shares,  establishing a period of least
30 days from the date of such notice,  during which  holders shall convert their
Preferred Shares into shares of Common Stock at the Conversion  Price, and after
which  all  conversion  rights  of  such  holders  shall  lapse  and  completely
terminate.

    (e) A right to convert  Preferred  Shares into shares of Common  Stock under
paragraph  (c) or (d) of this  Section  6 shall  be  exercised  by a  holder  by
delivering to the Corporation during regular business hours, or to such agent as
may be designated by the Corporation,  the original  certificate or certificates
for the shares to be converted, duly endorsed or assigned either in blank or tot
he Corporation,  accompanied by written notice in substantially the form annexed
hereto as Exhibit A, stating  that the holder  elects to convert such shares (or
the amount  thereof as to which the conversion  right is to be exercised,  which
amount  shall be not less than that  represented  by shares  having an aggregate
Original  Cost of $5,000) and stating the name or names (with address and Social
Security or Federal Taxpayer  Identification Number) in which the certificate or
certificates  for the shares of Common Stock are to be issued.  Conversion shall
be deemed to have been effected on the date when the aforesaid  delivery is made
(the "Conversion Date"). As promptly as practicable thereafter,  the Corporation
shall  issue and  deliver  to such  holder  (or upon the  written  order of such
holder) to the place  designated by such holder,  a certificate or  certificates
for the number of shares of Common Stock to which such holder is  entitled.  The
person in whose name the certificate or certificates  for Common Stock are to be
issued shall be deemed to have become a stockholder  of record on the applicable
Conversion  Date unless the transfer books of the Corporation are closed on that
date, in which event such person shall be deemed to have become a stockholder of
record on the next  succeeding  date on which the transfer books are open.  Upon
conversion  of only a portion of the number of shares  covered by a  certificate
representing shares of Series A Preferred Stock surrendered for conversion,  the
Corporation shall issue and deliver to such holder, or upon the written order of
the holder of the certificate so surrendered  for conversion,  at the expense of
the  Corporation,  a new  certificate  covering the number of shares of Series A
Preferred  Stock  representing  the  unconverted  portion of the  certificate so
surrendered.

    (f) The Corporation  shall, at all times when Series A Preferred Stock shall
be  outstanding,  reserve and keep  available out of its authorized but unissued
stock,  for the purpose of effecting the conversion of Series A Preferred Stock,
such number of its duly authorized  shares of Common Stock as shall from time to
time be sufficient to effect the conversion of all outstanding  shares of Series
A Preferred Stock.

    (g) All shares of Common  Stock which may be issued in  connection  with the
conversion  provisions set forth herein will, upon issuance by the  Corporation,
be validly issued,  fully paid and  non-assessable.  No adjustment shall be made
for dividends on any share of Series A Preferred  Stock which is being converted
(unless such dividends have been accrued and are unpaid as the Conversion  Date)
or on any share of Common  Stock  issued on  exercise  of a holder's  Conversion
Right.

    (h) No fractional  shares of Common Stock shall be issued upon conversion of
the Series A Preferred Stock and, in lieu of any fractional  shares to which the
holder  would  otherwise  be  entitled,  the  number of  shares of Common  Stock
issuable upon conversion shall be rounded to the nearest whole number.

    (i) All shares of Series A Preferred Stock which shall have been surrendered
for  conversion or exchange as herein  provided  shall no longer be deemed to be
outstanding,  and all rights with respect to such shares,  including the rights,
if any, to receive notices and to vote, shall immediately cease and terminate on
the Conversion  Date, with respect  Preferred  Shares which have been converted,
and on the specified  effective date of exchange for Preferred Shares which have
been  exchanged,  except only the right of the holders thereof to receive shares
of Common  Stock,  or Public  Offering  Securities,  in  conversion  or exchange
therefor. Any shares of Series A Preferred Stock so converted or exchanged shall
be retired and canceled and shall not be reissued,  and the Corporation (without
the need for  stockholder  action)  may from time to time take such  appropriate
action as may be necessary to reduce the authorized number of shares of Series A
Preferred Stock accordingly.

                                       7


    (j) The Corporation  shall pay any and all issue and other taxes that may be
payable in respect of any  issuance or  delivery of shares of Common  Stock upon
conversion of shares of Series A Preferred Stock pursuant to this Section 6. The
Corporation shall not, however,  be required to pay any tax which may be payable
in respect of any  transfer  involved in the  issuance and delivery of shares of
Common Stock in a name other than that in which the shares of Series A Preferred
Stock so converted  were  registered,  and no such issuance or delivery shall be
made unless and until the person or entity  requesting such issuance has paid to
the  Corporation  the  amount  of  any  such  tax  or  has  established,  to the
satisfaction of the Corporation, that such tax has been paid.

7.     Adjustments to Conversion Price.

    The  Conversion  Price (which is initially  established at $.41 per share of
Common Stock) in effect from time to time shall be subject to adjustment (to the
nearest cent) from time to time as follows:

    (a) If the  Corporation,  at any time after the Minimum  Closing Date and at
any time prior to the conversion of a Preferred  Share shall have subdivided its
outstanding  shares of Common  Stock by  recapitalization,  reclassification  or
split-up  thereof,  or if  the  Corporation  shall  have  declared  a  stock  or
distributed  shares of Common Stock to its  stockholders,  the Conversion  Price
immediately prior to such conversion shall be proportionately  increased; and if
the Corporation,  prior to such conversion,  shall have at any time combined the
outstanding  shares of Common  Stock by  recapitalizatoin,  reclassification  or
comparable  combination  thereof, the Conversion Price immediately prior to such
conversion shall be proportionately increased.

    (b)  In  case  the  Corporation,  after  the  Minimum  Closing  Date,  shall
consolidate   with  or  merge  into  another   corporation   or  convey  all  or
substantially all of its assets to another  corporation,  then, and in each such
case, the Conversion  Prices shall be adjusted in such manner that the holder of
Preferred Shares, upon the conversion thereof as provided in Section 6 above, at
any time after the  consummation  of such  consolidation,  merger or conveyance,
shall be entitled to received  the  securities  or property to which such holder
would have been entitled upon such consummation if such holder had exercised his
right to convert such Preferred Shares immediately prior thereto.

    (c) For purposes hereof,  the term "Additional Shares of Common Stock" shall
mean all shares of Common  Stock  issued by the  Corporation  after the  Minimum
Closing Date, or shares of Common Stock issuable upon  conversion or exchange of
any  securities  (including,  for this purpose,  preferred  stock other than the
Preferred  Shares,  and notes and  debentures)  convertible  into  Common  Stock
("Convertible Securities"), but not warrants or options issued after the Minimum
Closing  Date,  except to the  extent  such  warrants  or options  are  actually
exercised. If the Corporation at any time or from time to time after the Minimum
Closing  Date shall  agree to issue any  Convertible  Securities  or shall fix a
record date for the determination of holders of any class of securities entitled
to receive any such Convertible Securities, then the maximum number of shares of
Common Stock (as set forth in the instrument  relating thereto without regard to
any  provision  contained  therein for a subsequent  adjustment  of such number)
issuable upon the conversion such  Convertible  Securities shall be deemed to be
Additional  Shares of Common Stock,  but only as of the time of such issuance of
Convertible  Securities  or, in case such a record  date shall have been  fixed,
only as of the close of business on such record date,  provided that  Additional
Shares of Common  Stock  shall not be  deemed  to have been  issued  unless  the
consideration per share (determined pursuant to paragraph (e) of this Section 7)
of such Additional Shares of Common Stock would be less than the Adjustment Base
Price as  defined  below in effect on the date of an  immediately  prior to such
issue, or such record date, as the case may be, and provided further that in any
such case in which  Additional  Shares of Common  Stock are  deemed to be issued
pursuant to this  paragraph (c), no further  adjustment in the Conversion  Price
shall be made upon the  subsequent  issuance of Common  Stock at the time of the
actual conversion of such Convertible Securities.

    (d) In the event the Corporation shall at any time after the Minimum Closing
Date issue Additional  Shares of Common Stock,  including  Additional  Shares of
Common  Stock deemed to be issued  pursuant to  paragraph  (c) of this Section 7
(except for issuances of Common Stock  described in paragraph (f) below) without
consideration or for a consideration  per share less than the greater of (a) the
applicable  conversion Price in effect  immediately prior to such issuance,  and
(B) 50% of the Current Market Value per share of Common Stock (as defined below)
as of the date of such  issuance  (such  greater  amount  being  defined  as the
"Adjustment Base Price"),  then and in such event,  such Conversion Prices shall
be reduced,  concurrently  with such  issuance,  to a price  (calculated  to the
nearest cent) determined by multiplying such Conversion Price by a fraction: (A)
the  numerator  of which  shall be (1) the  number of  shares  of  Common  Stock
outstanding  immediately prior to such issuance plus (2) the quotient derived by
dividing the  aggregate  consideration  received  from such issuance of Addition
Shares of Common Stock by the Adjustment Base Price;  and (B) the denominator of
which  shall be the  number of shares of Common  Stock  outstanding  immediately
prior to such issue plus the number of such Additional Shares of Common Stock so
issued.  For purposes  hereof,  Current Market Value shall mean the Common Stock
average  closing  price  over a period  of 60  trading  days  ending  on the day
immediately  preceding  the date of issuance of the shares which are the subject
of the above calculations.

                                       8


    (e) for  purposes  of  Paragraph  (d) of this  Section 7, the  consideration
received by the  Corporation  for the issue of any  Additional  Shares of Common
Stock referred to therein shall be computed as follows:

         Cash and Property:  Such consideration shall:

    (i)  insofar as it consists  of cash,  be  computed  at the gross  amount of
    aggregate  cash  received  by the  Corporation,  excluding  amounts  paid or
    payable for accrued interest and the costs of the issuance;

    (ii) insofar as it consists of property  other than cash, be computed at the
    fair market value  thereof at the time of such issue,  as determined in good
    faith by the Board of Directors; and

    (iii) in the event  Additional  Shares of Common  Stock are issued  together
    with other  shares or  securities  or other  assets of the  Corporation  for
    consideration  so  received,  computed  as  provided in clauses (i) and (ii)
    above, as determined in good faith by the Board of Directors.

    (f) Notwithstanding  anything to the contrary contained in this Section 7 or
elsewhere  in  these  Certificate  of  Designation,   the  following  issuances,
transactions  or occurrences  shall be excluded from those events  requiring any
adjustment in accordance with Paragraph (d):

    (i)  The accrual or payment in kind of  dividends  on the Series A Preferred
         Stock;

    (ii) The issuance or re-issuance of the Preferred Shares to any investors in
         the Private  Placement  (or any  subsequent  issuance or  reissuance to
         their  transferees)  and any exchange,  conversion or redemption of any
         Preferred  Shares  (and of any  shares  of  Series  A  Preferred  Stock
         representing  dividends  paid in kind) in  accordance  with  provisions
         governing such  exchange,  conversion or redemption as set forth in the
         corporation's Articles of Incorporation, Certificate of Designation and
         By-Laws;

    (iii)The  issuance  to  any  of  the  Corporation's  executives,  directors,
         employees and consultants of options,  warrants or shares granted under
         any incentive,  stock option,  bonus or other benefit plan,  program or
         policy  of  the  Corporation,  provided  that  such  issuances  in  the
         aggregate do not exceed 15% in the aggregate of the Corporation's  then
         outstanding shares of Common Stock;

    (iv) The  issuance of shares of Common Stock upon the exercise of any option
         or warrant of the  Corporation  outstanding on the Minimum Closing Date
         (including  all  warrants  to be issued to the  placement  agent in the
         Private  Placement,  whether  issued  on or after the  Minimum  Closing
         Date);

    (v)  The issuance of shares of Common Stock,  or warrants or options for the
         purchase  of shares  of  Common  Stock,  to pay,  settle or  compromise
         Corporation obligations to suppliers, vendors,  contractors,  licensors
         and joint venture partners,  including, without limiting the generality
         of the foregoing,  Duke University and assignees or designees of Warren
         C. Stearns and Stearns Management Company; and

    (vi) The future issuance of shares,  or options or warrants for the purchase
         of  shares,  at a  discount  from  the  current  market  value,  to the
         placement agent in the Private Placement or to another placement agent,
         or to an underwriter,  bank, commercial lender or other institution, or
         to a  broker-dealer  or  investor  which  is  furnishing  or  arranging
         financing for the Company,  provided that any such issuance is not at a
         price which is less than the Adjustment Base Price, it being understood
         that,  if such  price  is less  than the  Adjustment  Base  Price,  the
         provisions  of  Paragraph  (d) of  this  Section  7  shall  govern  the
         adjustment to be made to the Conversion Price.

    (g)  The   Corporation   will  not,  by  amendment  of  its  Certificate  of
Incorporation or through any reorganization,  transfer of assets, consolidation,
merger, dissolution,  issue or sale of securities or any other voluntary action,
avoid or seek to avoid the  observance or  performance of any of the terms to be
observed or preformed  hereunder by the  Corporation,  will at all times in good
faith assist in the carrying out of all the  provisions of this Section 7 and in
the taking of all such actions as may be necessary  or  appropriate  in order to
protect the  conversion  rights of the  holders of the Series A Preferred  Stock
against impairment.

                                       9


    (h) Upon the occurrence of each adjustment or readjustment of the Conversion
Price pursuant to this Section 7, the  Corporation at its expense shall promptly
compute such  adjustment or readjustment in accordance with the terms hereof and
furnish to each  holder of Series A  Preferred  Stock,  upon the request of such
holder, a certificate  setting forth such adjustment or readjustment and showing
the facts upon  which  such  adjustment  or  readjustment  is based and the then
Conversion Price.

8.     Redemption.

    (a) Beginning six (6) months after the Minimum Closing Date the Corporation,
at its sole option,  expressed by resolution of its Board of Directors, may call
for  redemption and may redeem shares of Series A Preferred  Stock in whole,  or
from time to time in part, upon notice as set forth below.  the redemption price
per share of Series A Preferred  Stock shall be equal to 105% of the Liquidation
Preference plus accrued and unpaid dividends.

    (b)  Notice  of  any  redemption  of  the  Series  A  Preferred  Stock  (the
"Redemption  Notice") shall be given at least 30 days prior to the date fixed in
such notice for such redemption (the "Redemption Date") to each holder of record
of shares of Series A  Preferred  Stock,  at such  holder's  address as the same
shall appear on the books of the  Corporation.  Such noticed  shall  specify the
time and place of redemption,  the redemption  price,  and, if less than all the
outstanding  Preferred  Shares  are  to be  redeemed,  shall  also  specify  the
proportion of shares which are to be redeemed.

    (c) If any such notice of  redemption  shall have been duly given and if, on
or before the Redemption  Date specified  therein,  all funds necessary for such
redemption shall have been set aside by the Corporation, separate and apart from
its other funds,  in trust for the pro rata benefit of the holders of the shares
so called for  redemption,  so as to be and continue to be  available  therefor,
then,  notwithstanding  that any certificate for shares so called for redemption
shall not have  been  surrendered  for  cancellation,  al  shares so called  for
redemption  shall no longer be deemed  outstanding  on and after the  Redemption
Date,  and the right to receive  dividends  thereon  and all other  rights  with
respect  to such  shares  shall  forthwith  on such  Redemption  Date  cease and
terminate,  except only the right of the  holders  thereof to receive the amount
payable on redemption, without interest.

    (d) From and after the giving of the notice of redemption, holders of Series
A Preferred  Stock  shall  continue to have the  conversion  rights  provided in
Section 6, which rights shall continue in effect until the Redemption Date.

    (e) Shares of Series A Preferred  Stock which have been redeemed,  purchased
or  otherwise  acquired by the  Corporation  shall be canceled  and shall not be
subject to re-issuance by the Corporation for any purpose.

9.     General.

    (a) The  corporation  shall  not  amend,  alter or repeal  the  preferences,
special  rights or other powers of the Series A Preferred  Stock so as to affect
adversely  the  Series  A  Preferred  Stock,  without  the  written  consent  or
affirmative vote of the holders of a majority of the then outstanding  shares of
Series A Preferred Stock,  given in writing or by vote at a meeting,  consenting
or  voting  (as the  case may be)  separately  as a class,  in  accordance  with
applicable  law.  For this  purpose,  without  limiting  the  generality  of the
foregoing,  the  authorization of any shares of capital stock with preference or
priority  over the Series A  Preferred  Stock as to the right to receive  either
dividends or amounts  distributable upon liquidation,  dissolution or winding up
of the  Corporation  shall be deemed to affect  adversely the Series A Preferred
Stock,  and the  authorization  of any shares of capital  stock on a parity with
Series A Preferred Stock as to the right to receive either  dividends or amounts
disbributable  upon  liquidation,  dissolution or winding up of the  Corporation
shall not be deemed to affect adversely the Series A Preferred Stock.

    (b) The  number of  authorized  shares of  Series A  Preferred  Stock may be
increased  (but  only for the  purpose  of  providing  a  sufficient  number  of
authorized Preferred Shares of the payment of dividends on outstanding Preferred
Shares) or decreased  (but not below the number of shares then  outstanding)  by
the directors of the Corporation.

    (c) Any of the rights of the holders of Series A  Preferred  Stock set forth
herein may be waived by the affirmative vote of the holders of a majority of the
shares of Series A Preferred Stock then outstanding.

    (d) Fractional  shares of Series A Preferred Stock may be issued as required
in  connection  with the payment of dividends  or transfers of Preferred  Shares
among holders.

                                       10


10.    Notices.

    (a) Any  notices  required  to be given to any holder of Series A  Preferred
Stock shall be deemed  properly  given if deposited  in the United  States mail,
postage  prepaid,  or sent by  facsimile  or by  overnight  or express  delivery
service,  followed  by  duplicate  notice via United  States  first  class mail,
postage prepaid,  and addressed to the holder of record at such holder's address
appearing at the books of the Corporation.

(b) In case:

    i.  of any capital  reorganization of the Corporation,  any reclassification
        of the capital stock of the Corporation,  any consolidation or merger of
        the Corporation with or into another  corporation,  or any conveyance of
        all or  substantially  all of the assets of the  Corporation  to another
        corporation; or

    ii. of any voluntary or involuntary  dissolution,  liquidation or winding up
        of the Corporation; or

    iii.any other event  specified in this  Certificate  requiring the taking of
        such a record.

    Then,  and in each such  case,  the  Corporation  shall  mail or cause to be
mailed to each holder a notice specifying, as the case may be, the date on which
a record is to be taken for the foregoing purposes and providing the information
reasonably  required in order enable to holders of record of Preferred Shares to
exercise the rights conferred by this Certificate of Designation.

    THIRD: The  reclassification  of authorized but unissued shares as set forth
in this Certificate of Designation  does not increase the authorized  capital of
the Corporation or the aggregate par value thereof.

    IN  WITNESS  WHEREOF,   the  Corporation  has  caused  this  Certificate  of
Designation for its Series A 10% Convertible Preferred Stock to be duly executed
by its President  and by its  Secretary,  respectively,  this 15th day of August
2000.

     CELSION (DELAWARE) CORPORATION

     By:   /S/SPENCER J. VOLK
           ----------------------------------------
              Spencer J. Volk
              President and Chief Executive Officer

     By:  /S/JOHN MON
          -----------
             John Mon, Secretary

                                       11



                                                                       EXHIBIT A

                         CELSION (DELAWARE) CORPORATION

        NOTICE OF CONVERSION OF SERIES A 10% CONVERTIBLE PREFERRED STOCK

(To be  Executed  by the  Registered  Holder in order to  Convert  the  Series A
Preferred Stock)

    The undersigned  Holder hereby  irrevocably  elects to convert ___ shares of
Series A Preferred Stock,  represented by stock certificate No(s). ________ (the
"Preferred Stock  Certificates") into shares of common stock ("Common Stock") of
Celsion Corporation  according to the conditions set forth in the Certificate of
Designation  for Series a Preferred  Stock,  as of the date  written  below.  If
shares are to be issued in the name of a person other than the undersigned,  the
undersigned  will pay all transfer  taxes  payable  with respect  thereto and is
delivering herewith such certificates.  No fee will be charged to the Holder for
any  conversion,  except  for  transfer  taxes,  if  any.  A copy of each of the
Preferred Stock Certificates being converted is attached hereto.

     Date of Submission:______________________

     Number of Share of Series A 10% Convertible
     Preferred Stock to be Converted:____________

     Name of Holder:________________________

     By:___________________________________

     Title:__________________________________

     Address:_______________________________

     Social Security or

     Federal Taxpayer ID No:__________________

IMPORTANT

    No shares of  Common  Stock  will be  issued  until  the  original  Series A
Preferred Stock Certificates(s) to be converted and the Notice of Conversion are
received by the Company.  The Holder shall fax, or otherwise  deliver, a copy of
this completed and fully executed Notice of Conversion to the Corporation at the
office of the  Corporation or such other location  designated by the Corporation
and shall  deliver,  at the same time,  the  original  Series A Preferred  Stock
Certificate(s)  representing the Series A Preferred Stock being converted,  duly
endorsed for transfer.

                                       12