UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (date of earliest event reported):    April 28, 2006

                      BIOFORCE NANOSCIENCES HOLDINGS, INC.
             ------------------------------------------------------
             (Exact name of registrant as specified in its charter)

            Nevada                      000-51074                76-3078125
- ----------------------------          ------------          -------------------
(State or other jurisdiction          (Commission              (IRS Employer
      of incorporation)               File Number)          Identification No.)

              1615 Golden Aspen Drive, Suite 101, Ames, Iowa 50010
                    (Address of principal executive offices)

Registrant's telephone number, including area code: (515) 233-8333

Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions:

[ ]  Written  communications  pursuant to Rule 425 under the  Securities Act (17
     CFR 230.425)

[ ]  Soliciting  material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
     240.14a-12)

[ ]  Pre-commencement   communications  pursuant  to  Rule  14d-2(b)  under  the
     Exchange Act (17 CFR 240.14d-2(b))

[ ]  Pre-commencement   communications  pursuant  to  Rule  13e-4(c)  under  the
     Exchange Act (17 CFR 240.13e-4(c))





                                    FORM 8-K

Section 4 - Matters Related to Accountants and Financial Statements

Item 4.01  Changes in Registrant's Certifying Accountant

     We  have  terminated  Moore  &  Associates,   Chartered,  Certified  Public
Accountants,  as our  independent  certifying  accountants,  effective April 28,
2006. The termination of our relationship with Moore & Associates, Chartered was
not  presented  to our  board  of  directors.  Moore  &  Associates  became  our
certifiying accountants on October 20, 2005.

     Moore & Associates  audit report to our financial  statements  for the year
ended December 31, 2005, includes a modification expressing substantial doubt as
to our  company's  ability to  continue  as a going  concern  because we had not
established  an ongoing  source of revenues  sufficient  to cover our  operating
costs.  Our ability to continue as a going  concern is  dependent  on  obtaining
adequate capital to fund future operating losses until we become profitable. The
audit  report  contains  no other  adverse  opinion,  disclaimer  of  opinion or
modification as to uncertainty, audit scope or accounting principle.

     In  connection  with its audit  for the 2005  fiscal  year and the  interim
periods until the date of  termination,  there have been no  disagreements  with
Moore  &  Associates  on any  matter  of  accounting  principles  or  practices,
financial  statement  disclosure,  or auditing scope or procedures which, if not
resolved to the  satisfaction of Moore & Associates would have caused it to make
reference to the subject matter of the  disagreement in connection in its report
on the financial statements.

     During our two most recent  fiscal  years and through  April 28, 2006 there
have  been  no  reportable   events  as  set  forth  in  Regulation   S-B,  Item
304(a)(1)(iv).  We have provided Moore & Associates with a copy of this Form 8-K
and requested  that it furnish us with a letter  addressed to the Securities and
Exchange  Commission  stating whether or not Moore & Associates  agrees with the
above  statements.  A copy of the letter provided to us by Moore & Associates in
response to this request is filed as Exhibit 16.1 to this Form 8-K.

     Also on April 28,  2006,  our board of  directors  unanimously  approved  a
resolution  to  engage  Chisholm  Bierwolf  &  Nilson,   LLC,  Certified  Public
Accountants,  to become our new independent certifying  accountants.  During the
two most recent  fiscal years and through  April 28, 2006, we have not consulted
with Chisholm Bierwolf & Nilson regarding:

         (i)  the   application   of   accounting   principles  to  a  specified
         transaction, either completed or proposed, or the type of audit opinion
         that might be  rendered  on our  financial  statements,  and no written
         report or oral  advice was  provided to us by  concluding  there was an
         important factor to be considered by us in reaching a decision as to an
         accounting, auditing or financial reporting issue; or

         (ii) any matter that was the subject of a disagreement, as that term is
         defined  in Item  304(a)(1)(iv)  of  Regulation  S-B  and  the  related
         instructions  thereto,  or a  reportable  event,  as set  forth in Item
         304(a)(1)(iv) of Regulation S-B.

Section 9 - Financial Statements and Exhibits

Item 9.01     Financial Statements and Exhibits

     (c) Exhibits

       Exhibit No.Description

         16.1     Letter regarding change in certifying accountant

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                                   SIGNATURES


     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.


                                     BIOFORCE NANOSCIENCES HOLDINGS, INC.



Date:   August 7, 2006               By         /S/ ERIC HENDERSON
                                        ----------------------------------------
                                          Eric Henderson
                                          Chief Executive Officer



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