Exhibit 16.1 - Letter re: Change of Certifying Accountant MOORE & ASSOCIATES, CHARTERED ACCOUNTANTS AND ADVISORS PCAOB REGISTERED August 7, 2006 Office of the Chief Accountant Securities and Exchange Commission 100 F Street N.E. Washington, DC 20549 Ladies and Gentlemen: This letter will confirm that we reviewed Item 4.01 of the Form 8-K of BioForce Nanosciences Holdings, Inc. dated August 7, 2006, captioned "Changes in Registrant's Certifying Accountant," and that we agree with the statements made therein as they relate to Moore & Associates, Chartered. We are not in a position to agree or disagree with the statements in Item 4.01 regarding the engagement of Chisholm Bierwolf & Nilson, LLC. We hereby consent to the filing of this letter as an exhibit to the foregoing report on Form 8-K. /S/ Moore & Associates, Chartered - -------------------------------------- Moore & Associates, Chartered Las Vegas, Nevada 2675 S. JONES BLVD. SUITE 109, LAS VEGAS, NEVADA 89146 (702) 253-7511 Fax: (702)253-7501