UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                   FORM 8-K/A

                                 CURRENT REPORT

     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (date of earliest event reported):    November 14, 2006

                      BIOFORCE NANOSCIENCES HOLDINGS, INC.
             ------------------------------------------------------
             (Exact name of registrant as specified in its charter)

          Nevada                   000-51074                 74-3078125
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(State or other jurisdiction      (Commission             (IRS Employer
      of incorporation)            File Number)          Identification No.)

              1615 Golden Aspen Drive, Suite 101, Ames, Iowa 50010
                    (Address of principal executive offices)

Registrant's telephone number, including area code: (515) 233-8333


Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions:


[ ]  Written  communications  pursuant to Rule 425 under the  Securities Act (17
     CFR 230.425)

[ ]  Soliciting  material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
     240.14a-12)

[ ]  Pre-commencement   communications  pursuant  to  Rule  14d-2(b)  under  the
     Exchange Act (17 CFR 240.14d-2(b))

[ ]  Pre-commencement   communications  pursuant  to  Rule  13e-4(c)  under  the
     Exchange Act (17 CFR 240.13e-4(c))









                                   FORM 8-K/A

Explanatory Note

     On November 14, 2006, we filed a Form 8-K/A discussing the  restatement of
certain financial  statements as of December 31, 2005 and March 31, 2006 and for
the  three-month  periods ended March 31, 2005 and 2006. We attached as Exhibits
to that Form 8-K/A the restated financial statements of our subsidiary, BioForce
Nanosciences, Inc., for the years ended December 31, 2005 and 2004.

     This amendment to the Form 8-K/A is being filed to include Item 4.02 as set
forth below.

Section 4 - Matters Related to Accountants and Financial Statements

Item 4.02      Non-Reliance  on  Previously  Issued  Financial  Statements  or a
               Related Audit Report or Completed Interim Review.
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     On September 20, 2006, we received  correspondence  from the Securities and
Exchange  Commission  ("SEC")  dated  September 14, 2006. In that letter the SEC
raised  questions  about  the  method we used to  record  beneficial  conversion
features of certain debt that we had outstanding as of December 31, 2005.  After
appropriate research, we concluded that our accounting for this item had been in
error.  Accordingly,  the Form 10-QSB we originally filed for the fiscal quarter
ended March 31, 2006,  and the amended Form 10-QSB for the fiscal  quarter ended
March 31, 2006 we filed on August 7, 2006,  should no longer be relied upon.  We
filed an amended  Quarterly  Report on Form 10-QSB for the fiscal  quarter ended
March 31, 2006 on November 9, 2006 to reflect the proper accounting treatment.

     On  February  28,  2007,  we  learned  as a part of  conducting  accounting
procedures  for the year ended  December  31, 2006 that we had not  recorded our
liability  for accrued  vacation  pay for staff as of  December  31, 2005 in the
amount of $66,295. Accordingly, our financial statements as of December 31, 2005
and for the year ended  December  31, 2005 as  reflected  in our  amended  Forms
10-QSB for the three  months  ended March 31, 2006 and for the six months  ended
June 30, 2006,  and in our Form 10-QSB for the nine months ended  September  30,
2006,  should no  longer be relied  upon.  We will  present  restated  financial
statements  for the year ended  December 31, 2005 as a part of our upcoming Form
10-KSB filing for the year ended December 31, 2006. The restatement will reflect
a net loss for the year ended  December 31, 2005 of  $2,092,488  rather than the
previously  reported loss of  $2,026,193,  total  liabilities as of December 31,
2005 of $1,330,755  rather than the  previously  reported  total  liabilities of
$1,264,460,  and total  stockholders'  equity as of December 31, 2005 of $91,427
rather than the previously reported total stockholders' equity of $157,722.

     We have discussed the matters  disclosed in this Current Report on Form 8-K
with our independent registered public accounting firm.

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                                   SIGNATURES


     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.


                                    BioForce Nanosciences Holdings, Inc.



Date:  March 14, 2007               By:     S/ ERIC HENDERSON
                                       -----------------------------------------
                                                 Eric Henderson, Ph.D.
                                                 Chief Executive Officer




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