AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 14, 1999
                                                      REGISTRATION NO. 333-81109

================================================================================

                       SECURITIES AND EXCHANGE COMMISSION
================================================================================
                             WASHINGTON, D.C. 20549
                              ____________________

                                 AMENDMENT NO. 2
                                       TO
                                    FORM S-3
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933
                              ____________________
                               NETRIX CORPORATION
                 (Name of Small Business Issuer in its Charter)


           DELAWARE                                   54-1345159
  State or other Jurisdiction            (I.R.S. Employer Identification Number)
of Incorporation or Organization)

                              ____________________
                          13595 DULLES TECHNOLOGY DRIVE
                             HERNDON, VIRGINIA 22071
                                 (703) 742-6000
          (Address and Telephone Number of Principal Executive Offices)
                              ____________________
                                 LYNN C. CHAPMAN
                                    PRESIDENT
                          13595 DULLES TECHNOLOGY DRIVE
                             HERNDON, VIRGINIA 22071
                                 (703) 742-6000
            (Name, Address and Telephone Number of Agent for Service)
                              ____________________
                                 WITH A COPY TO:
                             JAY R. SCHIFFERLI, ESQ.
                            KELLEY DRYE & WARREN LLP
                               TWO STAMFORD PLAZA
                              281 TRESSER BOULEVARD
                           STAMFORD, CONNECTICUT 06901
                                 (203) 324-1400

APPROXIMATE  DATE  OF  COMMENCEMENT OF  PROPOSED SALE TO THE  PUBLIC: As soon as
     practicable after this Registration  Statement  becomes  effective.  If the
     only securities being registered on this Form are being offered pursuant to
     dividend or interest  reinvestment  plans,  please check the following box.
     |_|
If any of  the  securities being registered on this form are to be offered  on a
     delayed or continuous  basis  pursuant to Rule 415 under the Securities Act
     of 1933, other than securities  offered only in connection with dividend or
     interest reinvestment plans, check the following box. |X|

If this  form is  filed  to  register  additional  securities  for  an  offering
     pursuant to Rule 462(b) under the Securities Act, please check the
     following box and list the Securities Act registration statement number of
     the earlier effective registration statement for the same offering. |_|
     ______________
If this form is  a  post-effective amendment filed pursuant to Rule 462(c) under
     the  Securities  Act,  check the following box and list the  Securities Act
     registration   statement  number  of  the  earlier  effective  registration
     statement for the same offering. |_| ___________
If this form is  a  post-effective amendment filed pursuant to Rule 462(d) under
     the  Securities  Act,  check the following box and list the  Securities Act
     registration   statement  number  of  the  earlier  effective  registration
     statement for the same offering. |_| ___________
If delivery  of  the  prospectus  is  expected  to be made pursuant to Rule 434,
please check the following box.  |_|

THE REGISTRANT HEREBY AMENDS THIS  REGISTRATION  STATEMENT ON SUCH DATE OR DATES
AS MAY BE NECESSARY TO DELAY ITS EFFECTIVE DATE UNTIL THE REGISTRANT  SHALL FILE
A FURTHER AMENDMENT WHICH SPECIFICALLY  STATES THAT THIS REGISTRATION  STATEMENT
SHALL  THEREAFTER  BECOME  EFFECTIVE  IN  ACCORDANCE  WITH  SECTION  8(A) OF THE
SECURITIES  ACT OF  1933 OR  UNTIL  THIS  REGISTRATION  STATEMENT  SHALL  BECOME
EFFECTIVE ON SUCH DATE AS THE COMMISSION,  ACTING PURSUANT TO SAID SECTION 8(A),
MAY DETERMINE.
================================================================================






     The information in this  prospectus is not complete and may be changed.  We
may not sell these securities  until the  registration  statement filed with the
Securities and Exchange Commission is effective. This prospectus is not an offer
to  sell  these  securities  and it is not  soliciting  an  offer  to buy  these
securities in any state where the offer or sale is not permitted.






                 SUBJECT TO COMPLETION, DATED SEPTEMBER 14, 1999

PRELIMINARY PROSPECTUS


                               NETRIX CORPORATION


              This prospectus relates to 1,470,660 shares of common stock of
     Netrix Corporation that may be offered for sale by the security holders
     identified on page 7 of this prospectus under the caption "Selling Security
     Holders." We will not receive any proceeds from the sale of the common
     stock by the securityholders.

              Netrix Corporation's common stock is currently traded on the
     Nasdaq National Market under the trading symbol "NTRX." On September 9,
     1999, the last sale price of the common stock on that market was $3-5/16
     per share.


                                  ------------



              INVESTING IN THESE SECURITIES INVOLVES A HIGH DEGREE OF RISK. SEE
     "RISK FACTORS" BEGINNING ON PAGE 2.


                                  ------------



              Neither the Securities and Exchange Commission nor any state
     securities commission has approved or disapproved these securities or
     determined if this prospectus is truthful and complete. Any representation
     to the contrary is a criminal offense.


                                  ------------





               THE DATE OF THIS PROSPECTUS IS SEPTEMBER __, 1999.








         YOU SHOULD RELY ONLY UPON THE INFORMATION IN THIS PROSPECTUS. WE HAVE
NOT, AND THE SELLING SECURITY HOLDERS HAVE NOT, AUTHORIZED ANY OTHER PERSON TO
PROVIDE YOU WITH DIFFERENT INFORMATION. IF ANYONE PROVIDES YOU WITH DIFFERENT OR
INCONSISTENT INFORMATION, YOU SHOULD NOT RELY ON IT. WE ARE NOT, AND THE SELLING
SECURITY HOLDERS ARE NOT, MAKING AN OFFER TO SELL THESE SECURITIES IN ANY
JURISDICTION WHERE THE OFFER OR SALE IS NOT PERMITTED. YOU SHOULD ASSUME THAT
THE INFORMATION APPEARING IN THIS PROSPECTUS IS ACCURATE AS OF THE DATE ON THE
FRONT COVER OF THIS PROSPECTUS ONLY. OUR BUSINESS, FINANCIAL CONDITION, RESULTS
OF OPERATIONS AND PROSPECTS MAY HAVE CHANGED SINCE THAT DATE.


                               NETRIX CORPORATION

         Netrix Corporation is a worldwide provider of voice and data networking
products. Our products are designed to deliver multi-service networks for the
transport of voice and data that enable our customers to provide a wide variety
of voice and data services. We combine patented, switched, compressed voice
technology and advanced networking capabilities to provide networking solutions
that improve network performance and deliver an array of tarrifable network
services.

         Netrix was incorporated in Virginia in October 1985, and reincorporated
in Delaware in March 1987. Our principal executive offices are located at 13595
Dulles Technology Drive, Herndon, Virginia 20717, and our telephone number is
(703) 742-6000.

                                  RISK FACTORS

         This offering involves a high degree of risk. Before investing in these
securities, you should consider carefully the following risk factors, in
addition to the other information contained in this prospectus. Our business and
results of operations could be seriously harmed by any of the following risks.
The trading price of our common stock could decline due to any of these risks,
and you could lose part or all of your investment.

         WE INCURRED NET LOSSES IN EACH OF THE LAST TWO YEARS AND WE CANNOT BE
CERTAIN THAT WE WILL GENERATE SUFFICIENT REVENUES TO AGAIN BECOME PROFITABLE.

         For the years ended December 31, 1998 and 1997, respectively, we
incurred net losses of approximately $6.3 million and $8.6 million. Through June
1999, we have incurred additional losses of approximately $3.8. If we cannot
return to sustained profitability we will be forced to sell all or part of our
business, liquidate or seek to reorganize. We will continue to incur significant
sales and marketing, product development and general and administrative expenses
and, as a result, we will need to generate higher revenues to achieve and
sustain profitability on an annual basis. We expect to increase our revenues
through our new line of network exchange products; however, to date, sales of
network exchange products have not been sufficient to replace the decline in our
mature product sales. Although revenues from network exchange products have
grown in recent quarters, we cannot be certain that we will continue to achieve
revenue growth or realize sufficient revenues to achieve profitability.

         WE MAY REQUIRE ADDITIONAL CAPITAL TO FULLY IMPLEMENT OUR PLAN TO RETURN
TO PROFITABILITY, AND WE CANNOT BE CERTAIN THAT THE NECESSARY FUNDS WILL BE
AVAILABLE.

         Our ability to return to profitability is largely dependent upon our
ability to introduce new products and technologies and expand our sales efforts

                                       2


in new geographic and product markets. These activities require substantial
capital, and if we do not have access to sufficient funds, either from our own
operations or through third party financing, our ability to make these necessary
expenditures will be limited. As described in the preceding paragraph, there can
be no assurance that we will be able to obtain these necessary funds from our
own operations. If we are required to seek third party financing, we cannot
assure you that we will be able to obtain financing on terms favorable to us, or
at all. If we obtain additional funds by selling any of our equity securities,
the percentage ownership of our stockholders will be reduced, stockholders may
experience additional dilution, or the equity securities we issue may have
rights, preferences or privileges senior to the common stock. If adequate funds
are not available to us or available to us on satisfactory terms, we may be
required to limit our product development activities or other operations, or
otherwise modify our business strategy. These actions, if taken, could increase
the difficulties we face in returning to sustained profitability.

         WE RELY TO A LARGE EXTENT ON INDEPENDENT DISTRIBUTION CHANNELS AND THE
LOSS OF A SIGNIFICANT NUMBER OF DISTRIBUTORS COULD ADVERSELY EFFECT US.

         We rely on reseller channels, including distributors and systems
integrators, for a significant portion of our revenues. In particular, in
foreign markets we often have one distributor designated for an entire country,
and that distributor provides local support and service for our products. The
loss of one or more significant resellers could adversely affect our business
both in terms of:

          o    lost revenues;

          o    lost market presence; and

          o    the difficulties we would encounter in servicing customers
               introduced to us by our resellers if we do not have other
               resellers in that geographic area.

         WE ARE EXPOSED TO POTENTIAL DELAYS IN PRODUCT SHIPMENTS BECAUSE WE
CONTRACT OUT OUR PRODUCT MANUFACTURING AND SOME COMPONENTS FOR OUR PRODUCTS ARE
AVAILABLE TO US ONLY FROM A SINGLE SUPPLIER OR A LIMITED NUMBER OF SUPPLIERS.

         It is not economically feasible for us to develop our own product
manufacturing capacity in the foreseeable future. We rely on others to
manufacture our products and product components and this dependence exposes us
to potential interruptions or delays in product delivery. An interruption could
have a short term effect on our revenues and a longer term effect on our ability
to market our products. Currently, we rely on a single contract manufacturer to
assemble and test most of our products. Also, some of the components we use in
our products are available from only one source or a limited number of
suppliers. Although we have been able to obtain our products and these
components to date, our inability to develop alternative sources if and as
required in the future, or to obtain sufficient sole source or limited source
components as required, could result in delays or reductions in product
shipments.

         WE RELY ON A LIMITED NUMBER OF KEY EMPLOYEES, THE LOSS OF ANY OF WHOM
COULD ADVERSELY IMPACT OUR DEVELOPMENT.

         Our success depends to a significant degree upon the continued
contributions of our management, marketing, engineering and technical personnel,
many of whom would be difficult to replace. In addition, as we continue to
develop the network exchange product line and other new products, we will need
to attract and retain additional qualified personnel. There is intense
competition for qualified personnel in our industry, and there can be no
assurance that we will be able to attract and retain the qualified personnel
necessary for the development of our business. Loss of the services of any of
our key employees would be detrimental to our development. We do not have
employment contracts with our key employees and we do not have "key man" life
insurance on any of our officers or directors.


                                       3


         OUR INTELLECTUAL PROPERTY RIGHTS ARE AN IMPORTANT PROTECTION FOR OUR
PRODUCTS, AND WE COULD BE ADVERSELY AFFECTED IF OUR RIGHTS ARE CHALLENGED OR
CIRCUMVENTED BY COMPETITORS.

         Our ability to compete successfully within our industry is dependent in
part upon the patents and nondisclosure agreements that we have obtained, upon
technical measures that we take to protect confidential information and upon
trade secret, copyright and trademark laws that we rely on to establish and
protect our proprietary rights. If any of our proprietary rights are challenged
or circumvented by competitors or other companies are able to market
functionally similar products, systems or processes without infringing our
proprietary rights.

         BECAUSE A PORTION OF OUR REVENUES ARE DERIVED FROM SALES TO THE UNITED
STATES GOVERNMENT, WE COULD BE ADVERSELY AFFECTED BY GOVERNMENTAL RESTRAINTS OR
POLICY CHANGES.

         A portion of our revenues results from sales to the United States
government, primarily through systems integrators. The revenues generated by
this government business, which is spread across numerous agencies and
departments, could be adversely affected by governmental budgetary or fiscal
restraints or changes in governmental policy.

         OUR CERTIFICATE OF INCORPORATION AND BY-LAWS CONTAIN PROVISIONS THAT
COULD DELAY OR PREVENT A CHANGE IN CONTROL.

         Provisions of our certificate of incorporation and by-laws may have the
effect of discouraging, delaying or preventing a take-over attempt that could be
in the best interests of our stockholders. These include provisions that:

          o     separate our board of directors into three classes;

          o     limit the ability of our stockholders to call special
                stockholder meetings;

          o     require advance notice of nominations for directors and
                stockholder proposals to be considered at stockholder meetings;
                and

          o    require a vote greater than two-thirds to remove directors from
               office or amend many of the provisions of our certificate of
               incorporation and by-laws.

         Our board of directors also has the right, without further action of
the stockholders, to issue and fix the terms of preferred stock, which could
have rights senior to the common stock. We are also subject to the "business
combination" provisions of the Delaware General Corporate Law, which imposes
procedures impeding business combinations with "interested stockholders" that
are not approved of by our board of directors.

                                       4





                       WHERE YOU CAN FIND MORE INFORMATION

         We are subject to the informational requirements of the Securities
Exchange Act of 1934. As required by the Securities Exchange Act, we file
reports, proxy statements and other information with the SEC. The reports, proxy
statements and other information can be inspected and copied at the public
reference facilities maintained by the SEC at Judiciary Plaza, 450 Fifth Street,
N.W., Room 1024, Washington, D.C. 20549 and at regional offices of the SEC at
Citicorp Center, 500 West Madison Street, Chicago, Illinois 60661 and at Seven
World Trade Center, 13th Floor, New York, New York 10048. In addition, we are
required to file electronic versions of these documents through the SEC's
Electronic Data Gathering, Analysis and Retrieval System (EDGAR). The SEC
maintains a World Wide Web site at http://www.sec.gov that contains reports,
proxy and information statements and other information regarding registrants
that file electronically with the SEC. Copies of these materials may also be
obtained at prescribed rates from the Public Reference Section of the SEC, 450
Fifth Street, N.W., Judiciary Plaza, Room 1024, Washington, D.C. 20549. The
common stock is quoted on the Nasdaq National Market. Information regarding the
trading of our common stock on the Nasdaq National Market can be obtained from
the Nasdaq National Market, 9801 Washingtonian Boulevard, Gaithersburg, Maryland
20878 ((202) 496-2500).

         We have filed with the SEC a registration statement on Form S-3 under
the Securities Act of 1933 with respect to the securities being offered by this
prospectus. As permitted by the rules and regulations of the SEC, this
prospectus does not contain all the information set forth in the registration
statement. For further information with respect to us and the offer and sale of
the securities, reference is made to the registration statement. Statements
contained in this prospectus concerning the provisions of documents filed with
the registration statement as exhibits are necessarily summaries of those
documents, and each of these statement is qualified by reference to the copy of
the applicable document filed with the SEC. The registration statement may be
inspected without charge at the public reference facilities of the SEC at the
addresses contained in the preceding paragraph and copies of all or any part of
the registration statement may be obtained from the SEC at prescribed rates.

         Pursuant to the rules of the SEC, we are able to "incorporate by
reference" into this document the information that we have on file with the SEC.
This means that we may disclose important information to you by referring you to
other documents. The information incorporated by reference is considered to be
part of this prospectus. In addition, any later information we file with the SEC
and incorporated by reference will update and supersede the information referred
to or contained in this prospectus. We incorporate by reference the documents
listed below and any future filings we make with the SEC under section 13a,
13(c), 14 or 15(d) of the Exchange Act until this offering has been completed:

          o    Our Annual Report on Form 10-K for the year ending December 31,
               1998; and
          o    Our Quarterly Reports on Form 10-Q for the quarters ending
               March 31, 1999 and June 30, 1999.

                                       5


                SPECIAL NOTE REGARDING FORWARD LOOKING STATEMENTS

         Some of the information set forth in this prospectus includes "forward
looking statements" within the meaning of the Private Securities Litigation
Reform Act of 1995. In addition, from time to time, we may publish
"forward-looking statements" within the meaning of Section 27A of the Securities
Act and Section 21E of the Exchange Act or make oral statements that constitute
forward-looking statements. These forward-looking statements may relate to
matters such as anticipated financial performance, future revenues or earnings,
business prospectus, projected ventures, new products, anticipated market
performance and similar matters. The words "budgeted," "anticipate," "project,"
"estimate," "expect," "may," "believe," "potential" and similar statements are
intended to be among the statements that are forward looking statements. Because
these statements reflect the reality of risk and uncertainty that is inherent in
our business, actual results may differ materially from those expressed or
implied by the forward-looking statements. You are cautioned not to place undue
reliance on these forward looking statements, which are made as of the date of
this prospectus.

         The Private Securities Litigation Reform Act of 1995 provides a safe
harbor for forward-looking statements. In order to comply with the terms of the
safe harbor, we caution you that a variety of factors could cause our actual
results to differ materially from the anticipated results or other expectations
expressed in our forward-looking statements. These risks and uncertainties, many
of which are beyond our control, include, but are not limited to those set forth
under the caption "Risk Factors" on page 4 and in our filings with the SEC.

         We undertake no obligation to release publicly any revisions to the
forward looking statements to reflect events or circumstances after the date of
this prospectus or to reflect unanticipated events or developments.

           RECENT ANNOUNCEMENT OF MERGER WITH OPENROUTE NETWORKS, INC.

         On August 26, 1999, we entered into a letter of intent to merge with
OpenROUTE Networks, Inc. OpenROUTE is a public company whose shares are listed
on the Nasdaq National Market under the symbol "OPEN." Under the terms of the
proposed merger, we will be the surviving company, and we will issue shares of
our common stock in exchange for the shares of outstanding OpenROUTE stock.
Also, we will increase our board of directors to nine persons. Of the nine
directors, we will designate five directors, and four will be designated by
OpenROUTE. In its last report filed with the Securities and Exchange Commission,
OpenROUTE reported that it had 15,489,356 shares of common stock outstanding. We
have not yet entered into a binding merger agreement with OpenROUTE.

         We expect to complete the merger by year-end, although there will be a
number of conditions to completing the merger. Among the conditions will be:

             o   approval by our board of directors and the board of directors
                 of OpenROUTE;
             o   approval of the issuance of our common stock by a majority vote
                 of our stockholders;
             o   approval of the merger by a two-thirds vote of OpenROUTE's
                 stockholders; and
             o   passage of all waiting periods under the Hart-Scott-Rodino
                 Antitrust Improvements Act.

We expect the merger agreement will also include representations, warranties and
covenants by each party that are customary for this type of transaction.

                                       6



                                 USE OF PROCEEDS

         We will not receive any proceeds from the sale of common stock by the
selling security holders. If the warrants are exercised, we will receive up to
$208,000, reflecting the total exercise price.


                            SELLING SECURITY HOLDERS

         This prospectus relates to the resale of 1,470,660 shares of common
stock. This common stock is issuable upon the conversion of preferred stock or
the exercise of warrants we have recently issued. The terms of the issuances are
described in this section below under the caption "Sale of the preferred stock
and warrants." The following table sets forth, to our knowledge:

            o    the number of shares of common stock beneficially owned by each
                 selling security holder;

            o    the number of shares of common stock to be offered and sold by
                 the selling security holder; and

            o    the number of shares of common stock and percentage of
                 outstanding shares of common stock to be beneficially owned by
                 the selling security holder after the offer and sale
                 contemplated by this prospectus, assuming that all the shares
                 offered by the selling security holder are in fact sold.

         Unless otherwise indicated, to our knowledge, each person has sole
investment and voting power, if applicable (or shares these powers with his or
her spouse), with respect to the securities set forth in the following table.

         As of September 1, 1999 we had 11,562,906 shares of common stock issued
and outstanding.





                                                                                            Beneficial Ownership
                                                                                           After the Offering (1)
                                                                                       --------------------------------
                                               Number of Shares         Number of
                                              Beneficially Owned        Shares to        Number of
 NAME AND ADDRESS                            Prior to the Offering       be Sold          Shares         Percentage
 ----------------                            ---------------------       -------          ------         ----------
                                                                                              

Charles Ziegler                                    45,455                 45,455              ---           ---
c/o LIT
220 Bush, Suite 580
San Francisco, CA 94104

Donald Abramson                                    67,275                 67,275              ---           ---
220 Bush Street, #545
San Francisco, CA 94104

Downco Holdings, Ltd.                              72,725                 72,725              ---           ---
c/o Robert Goodman
1013 Cove Road
Mamaroneck, NY 10543

Paul Johnson                                       18,185                 18,185              ---           ---
1112 Park Avenue
New York, NY 10128


                                       7




                                                                                         Beneficial Ownership
                                                                                           After the Offering (1)
                                                                                       --------------------------------
                                               Number of Shares         Number of
                                              Beneficially Owned        Shares to        Number of
 NAME AND ADDRESS                            Prior to the Offering       be Sold          Shares         Percentage
 ----------------                            ---------------------       -------          ------         ----------
                                                                                            


Clifford T. Dirkes                                 36,365                 36,365            ---            ---
707 Golfview Road
Morrestown, NJ 08057

SoundShore Opportunity Holding Fund Ltd.           36,365                 36,365            ---            ---
c/o AIG
1281 East Main Street
Stamford, CT 06902

SoundShore Holdings Ltd.                           90,910                 90,910            ---            ---
c/o AIG
1281 East Main Street
Stamford, CT 06902

Triton Capital Investments                         90,910                 90,910            ---          ----
One Sansome, 39th Floor
San Francisco, CA 94104

Hull Overseas, Ltd.                                90,910                 90,910            ---          ---
152 West 57th Street
New York, NY 10019

Richard A. Levy and Susan C. Levy,                109,095                109,095            ---          ---
JTWROS
1258 Linder Avenue
Highland Park, IL 60035

St. Claire International, Ltd.                     36,365                 36,365               ---          ---
c/o Hedge Funds Services (BVI) Ltd.
Box 23
Ellen L. Shelton Building
Road Town, Tortola
British Virgin Islands

Special Situations Fund III, L.P.               1,454,200(2)             109,090       1,294,200            11.0
153 East 53rd Street, 51st Floor
New York, NY 10022

Special Situations Cayman Fund, L.P.            1,454,200(2)              36,365       1,294,200            11.0
153 East 53rd Street, 51st Floor
New York, NY 10022

Special Situations Technology Fund, L.P.        1,454,200(2)              14,545       1,294,200            11.0
153 East 53rd Street, 51st Floor
New York, NY 10022


                                       8




                                                                                         Beneficial Ownership
                                                                                           After the Offering (1)
                                                                                       --------------------------------
                                               Number of Shares         Number of
                                              Beneficially Owned        Shares to        Number of
 NAME AND ADDRESS                            Prior to the Offering       be Sold          Shares         Percentage
 ----------------                            ---------------------       -------          ------         ----------
                                                                                              


RKB Capital, L.P.                                 363,365                363,365               ---          ---
130 West Lake Street
Wayzata, MN 55391


Omicron Partners L.P.                             109,095                109,095               ---          ---
153 East 53rd Street, 48th Floor
New York, NY 10022


Abernathy Group                                   363,340                363,640               ---          ---
20 Exchange Place, 38th Floor
New York, NY 10005


Renwick Securities, Inc.                           57,000                 57,000               ---          ---
50 East 42nd Street, Suite 1306
New York, NY 10017



Coast Business Credit                              50,000                 50,000               ---          ---
a division of Southern Pacific Bank
1212 Wilshire Boulevard, Suite 1400
Los Angeles, California 90025

- ----------------------
* Less than 1 percent



(1)      Beneficial ownership is determined in accordance with the rules and
         regulations of the SEC and generally includes consideration of voting
         or investment power with respect to the securities at issue.
         Information with respect to beneficial ownership is based upon
         information as of September 1, 1999, and assumes that there is
         outstanding an aggregate of 11,562,906 shares of common stock, not
         including treasury shares. Except as otherwise indicated in the
         footnotes below, and subject to community property laws where
         applicable, we believe, based upon information furnished by selling
         security holders, that the persons named in this table have sole voting
         and investment power with respect to all shares of common stock shown
         as beneficially owned by them.

(2)      Based on a Schedule 13G dated February 12, 1999. Special Situation Fund
         III, L.P., Special Situations Cayman Fund, L.P. and Special Situations
         Technology Funds, L.P. are affiliated. Includes a total of 1,294,200
         shares of common stock and 160,000 shares of common stock issuable upon
         conversion of the preferred stock.

SALE OF THE PREFERRED STOCK AND WARRANTS

         During the period ended June 30, 1999, we raised funds through a
private offering of 298,187 shares of our Series A 8% convertible preferred
stock. We did not use an underwriter in the offering, although we did compensate
the persons who introduced us to investors, as described below. We sold the
preferred stock at $13.75 per share, which represented five times the price of
our common stock at the time we committed to undertake the offering. Each share
of preferred stock is convertible into shares of our common stock at a
conversion price of $2.75 per share, which represents five shares of common

                                       9


stock for every share of preferred stock. The conversion price of the preferred
stock will be proportionally adjusted if we undertake a stock split, stock
consolidation or stock dividend with respect to our common stock. This
registration statement provides for the resale of the common stock. Most of this
common stock is subject to limitations on transfer until May 2000. The resale
limitations will be lifted prior to May 2000 as follows:

          o  if the average closing bid price for our stock price is at least
             $3.43 for 10 consecutive trading days, 25% of the common stock
             may be sold;

          o  if the average closing bid price for our stock price is at least
             $4.29 for 10 consecutive trading days, an additional 25% of the
             common stock may be sold;

          o  if the average closing bid price for our stock price is at least
             $5.36 for 10 consecutive trading days, an additional 25% of the
             common stock may be sold; and

          o  if the average closing bid price for our stock price is at least
             $6.71 for 10 consecutive trading days, all remaining shares will
             may be sold.

         As of the date of this prospectus, our stock price has been above $3.42
for 10 consecutive trading days, so a portion of the shares have been released
form this transfer restriction.

         Each share of preferred stock has a liquidation preference equal to its
purchase price, plus accrued and unpaid dividends. Dividends are cumulative from
May 14, 1999, and are payable semi-annually, in arrears, on April 30 and October
31 of each year, commencing October 31, 1999. Dividends are payable in cash or
shares of common stock, at the our election. The preferred stock is redeemable
at our option at any time after the closing bid price for our common stock on
the NASDAQ Stock Market has equaled or exceeded $6.00 for 10 consecutive trading
days. The redemption price is $17.50 per share plus accrued but unpaid dividends
to the date of repurchase.

         We sold the preferred stock directly to the investors. Among the
investors was Special Situations Fund III, L.P., our largest stockholder, and
Special Situations Cayman Fund, L.P. and Special Situations Technology Fund,
L.P., each of whom is affiliated with Special Situations Fund III, L.P. Other
than through their position as a significant stockholder of Netrix, we have no
relationship with Special Situations Fund III, L.P. and its affiliates, and we
have no material relationship with any other purchaser of the preferred stock.

         In connection with the private placement, we received net proceeds of
approximately $4.0 million. We are using these proceeds to fund operations,
severance and other restructuring activities, and marketing and sales
initiatives.

          In connection with the offering of the preferred stock, we paid
compensation to Renwick Securities, Inc., who introduced investors to us. The
compensation was $88,000 in cash and warrants to purchase 32,000 shares of
common stock at $2.75 per share, subject to customary anti-dilution protections.

         Renwick Corporate Finance, which is wholly owned by Renwick Securities,
Inc., provides consulting services to us. In March 1999 we paid to Renwick an
initial retainer of $10,000 in cash and warrants to purchase 25,000 shares of
common stock at varying exercise prices of $3, $5 and $7 per share. We pay a
monthly retainer to Renwick of $12,500 in cash together with warrants to
purchase 3,333 shares of common stock at $3.75 per share. For consulting
services related to the financing represented by the private placement, we
issued to Renwick warrants to purchase 25,000 shares of common stock at varying
exercise prices of $3, $5 and $7 per share.

                                       10


         In April 1999, in connection with obtaining an amendment and waiver of
the minimum tangible net worth covenant  contained in our credit  agreement,  we
issued to Coast Business Credit, a division of Southern Pacific Bank, warrants
to acquire 50,000 shares of common stock.  The warrants are exercisable at $2.00
per share,  and are exercisable  until June 2004.  Other than in its capacity as
our primary lender, we have no relationship with Coast Business Credit.


                            DESCRIPTION OF SECURITIES

         Our authorized capital stock consists of 29,000,000 shares of common
stock, $.05 par value per share, of which 11,562,906 shares are outstanding,
fully paid and non-assessable prior to this offering, and 1,000,000 shares of
preferred stock, par value $.05 per share, none of which are outstanding prior
to this offering. An additional 4,825,000 shares of common stock are reserved
under our stock option plans, and there are currently 3,068,149 options
outstanding. In addition, since December 31, 1998, we have issued warrants to
acquire an aggregate of 349,498 shares of common stock.

PREFERRED STOCK

         Our board of directors is authorized, without further action by the
stockholders, to issue one million shares of preferred stock in one or more
series and to fix the rights, preferences, privileges and restrictions of the
preferred stock they issue, including dividend rights, dividend rates,
conversion rights, voting rights, terms of redemption, redemption prices and
liquidation preferences and the number of shares constituting and the
designation of any series. A majority of the common stock covered by this
prospectus is issuable by us upon conversion of our Series A 8% convertible
preferred stock. We issued this stock in May 1999, and its terms are described
above under the caption "Sale of the preferred stock and warrants" in the
section of this prospectus titled "Selling Stockholders."

         The rights and terms relating to any new series of preferred stock
could adversely affect the voting power or other rights of the holders of common
stock. Also, we issue preferred stock as a method of discouraging, delaying or
preventing a change in control of Netrix.

COMMON STOCK

         The holders of common stock are entitled to one vote for each share
held of record in the election of directors and with respect to all other
matters to be voted on by stockholders. Holders of shares of common stock do not
have cumulative voting rights. Therefore, the holders of more than 50 percent of
the shares voting for the election of directors can elect all of the directors.
The holders of common stock are entitled to receive dividends when, as and if
declared by the Board of Directors out of legally available funds. In the event
of liquidation, dissolution or winding up of Netrix, the holders of common stock
are entitled to share ratably in all assets remaining available for distribution
after payment of liabilities and after provision has been made for each class of
stock, if any, having preference over the common stock. Our common stock does
not provide to the holders any conversion, preemptive or other subscription
rights, and there are no redemption provisions applicable to the common stock.
The rights of the holders of common stock are subject to any rights that may be
fixed for holders of preferred stock, when and if any preferred stock is issued.
All of the shares of common stock currently outstanding are duly authorized,
validly issued, fully paid and non-assessable.



                                       11


WARRANTS

         There are currently outstanding approximately 349,498 warrants to
purchase common stock. Each warrant entitles the registered holder to purchase
one share of our common stock, $.05 par value, at exercise prices ranging from
$2.00 to $10.00 per share, exercisable at various times until June 30, 2004.

TRANSFER AGENT AND REGISTRAR

         The transfer agent and registrar for the common stock is American Stock
Transfer & Trust Company, whose address is 40 Wall Street, New York, New York,
10005, telephone number (212) 936-5100.


                              PLAN OF DISTRIBUTION

         The common stock may be offered and sold from time to time by one or
more of the selling security holders, or by pledgees, donees, transferees or
other successors in interest. No selling security holder is required to offer or
sell any of his common stock. The selling security holders anticipate that, if
and when offered and sold, the common stock will be offered and sold in
transactions effected on the Nasdaq Stock Market at then prevailing market
prices. These transactions could include block transactions. The selling
security holders reserve the right, however, to offer and sell the common stock
on any other national securities exchange on which the common stock is or may
become listed or in the over-the-counter market, in each case at then prevailing
market prices, or in privately negotiated transactions each at a price then to
be negotiated. All offers and sales made on the Nasdaq Stock Market or any other
national securities exchange or in the over-the-counter market will be made
through or to licensed brokers and dealers. No agreements, arrangements or
understandings have been entered into with any broker or dealer, and no brokers
or dealers have been selected, in connection with the offer and sale of the
common stock. All proceeds from the sale of the common stock will be paid
directly to the selling security holders and will not be deposited in an escrow,
trust or other similar arrangement. We will not receive any of the proceeds from
the sales of the common stock by the selling security holders. However, we will
receive proceeds from the exercise of the warrants by the selling security
holders. No discounts, commissions or other compensation will be allowed or paid
by the selling security holders or by us in connection with the offer and sale
of the common stock except that usual and customary brokers' commissions may be
paid by the selling security holders.

         The selling broker may act as agent or may acquire shares of common
stock or interests in common stock as principal or pledgee and may, from time to
time, effect distributions of shares of common stock or interests. If a dealer
is utilized in the sale of common stock in respect of which the prospectus is
delivered, the selling security holders will sell common stock to the dealer as
principal. The dealer may then resell the common stock to the public at varying
prices to be determined by the dealer at the time of resale.

         We and the selling security holders have agreed to indemnify each other
with respect to any liability that results from:

               o   any untrue statement or alleged untrue statement contained
                   in this prospectus; or

               o   any material omission or alleged omission from the
                   registration statement or this prospectus

to the extent the untrue statement or omission was included in the registration
statement or this prospectus in reliance upon information furnished by the
indemnifying party.

         We will pay the legal, accounting and other fees and expenses related
to the offer and sale of the common stock contemplated by this prospectus,
excluding commissions charged by any broker or dealer acting on behalf of a

                                       12


selling security holder. The fees and expenses we will pay are estimated to be
$10,000.


                                  LEGAL MATTERS

         The validity of the common stock offered by this prospectus will be
passed upon for Netrix by Kelley Drye & Warren LLP.


                                     EXPERTS

         The Audited Consolidated Financial Statements and Schedule incorporated
by reference in this prospectus and elsewhere in the registration statement have
been audited by the independent public accountant firm of Arthur Andersen LLP.
These reports are included in this prospectus in reliance upon Arthur Andersen
LLP's accounting and auditing authority and expertise in relation to the
provision of these reports.


                                       13




NO DEALER,  SALES PERSON OR OTHER PERSON HAS
BEEN  AUTHORIZED TO GIVE ANY  INFORMATION OR
TO MAKE ANY  REPRESENTATION NOT CONTAINED IN
THIS PROSPECTUS, AND, IF GIVEN OR MADE, THAT
INFORMATION  OR  REPRESENTATION  MUST NOT BE
RELIED  UPON AS HAVING  BEEN  AUTHORIZED  BY
NETRIX CORPORATION. THIS PROSPECTUS DOES NOT
CONSTITUTE   AN   OFFER   TO   SELL   OR   A
SOLICITATION  OF AN  OFFER TO BUY ANY OF THE          NETRIX CORPORATION
NETRIX   CORPORATION   SECURITIES   IN   ANY
JURISDICTION  TO ANY  PERSON  TO  WHOM IT IS
UNLAWFUL  TO  MAKE  AN  OFFER.  NEITHER  THE
DELIVERY  OF THIS  PROSPECTUS  NOR ANY  SALE              1,470,660
MADE  PURSUANT  TO  THIS  PROSPECTUS  SHALL,              Shares of
UNDER   ANY   CIRCUMSTANCES,    CREATE   ANY             Common Stock
IMPLICATION 1,470,660 THAT THERE HAS BEEN NO
CHANGE IN THE  AFFAIRS  OF NETRIX  SHARES OF
CORPORATION   SINCE   THE   DATE   OF   THIS
PROSPECTUS   OR  THAT   THE   COMMON   STOCK
INFORMATION  CONTAINED IN THIS PROSPECTUS IS
CORRECT  AS OF ANY  TIME  SUBSEQUENT  TO ITS           --------------
DATE.


              ----------------
                                                         PROSPECTUS

                                                        _____________
              TABLE OF CONTENTS

                                          PAGE

Netrix Corporation.........................2
Risk Factors...............................2
Where to Find Additional Information.......5
Special Note Regarding Forward Looking
     Statements............................6

Recent Announcement of Merger with
     OpenROUTE Networks, Inc. .............6

Use of Proceeds............................7       September __, 1999
Selling Security Holders...................7
Description of the Securities..............11
Plan of Distribution.......................12
Legal Matters..............................13
Experts....................................13





                                       14



                                     PART II

                   INFORMATION NOT REQUIRED IN THE PROSPECTUS


ITEM 14.  OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION

         The following table sets forth the estimated expenses to be incurred in
connection with the distribution of the securities being registered. The
expenses will be paid by Netrix Corporation.






                     TYPE OR NATURE OF EXPENSE                               AMOUNT TO BE PAID
                     -------------------------                               -----------------
                                                                       

SEC registration fee............................................                 $1,247.74
Accounting fees and expenses....................................                  5,000.00
Legal fees and expenses.........................................                  1,500.00
Miscellaneous...................................................                  1,000.00
                                                                                 ---------
Total...........................................................                 $8,747.74
                                                                                 =========



ITEM 15.  INDEMNIFICATION OF DIRECTORS AND OFFICERS

         Section 145 of the Delaware General Corporation Law (the "DGCL")
provides that a Delaware corporation may indemnify any person who was or is a
party or is threatened to be made a party to any threatened, pending or
completed action, suit or proceeding, whether civil, criminal, administrative or
investigative (a "proceeding") (other than an action by or in the right of the
corporation) by reason of the fact that he is or was a director, officer,
employee or agent of the corporation, or is or was serving at the request of the
corporation as a director, officer, employee or agent of another corporation,
partnership, joint venture, trust or other enterprise, against expenses
(including attorneys' fees), judgments, fines and amounts paid in settlement
actually and reasonably incurred by him in connection with that action, suit or
proceeding if he acted in good faith and in a manner he reasonably believed to
be in or not opposed to the best interests of the corporation, and, with respect
to any criminal action or proceeding, had no reasonable cause to believe his
conduct was unlawful. A Delaware corporation may indemnify any person under
Section 145 who was, is or is threatened to be made a party to any threatened,
pending or completed action or suit by or in the right of the corporation to
procure judgment in its favor, by reason of such fact as provided in the
preceding sentence, against expenses (including attorneys' fees) actually and
reasonably incurred by him in connection with the defense or settlement of that
action or suit, except that no indemnification shall be made in respect of the
an action or suit if he did not act in good faith and in a manner he reasonably
believed to be in or not opposed to our best interests and unless, and then only
to the extent that, a court of competent jurisdiction shall determine upon
application that he is fairly and reasonably entitled to indemnity for those
expenses as the court shall deem proper. A Delaware corporation must indemnify
any person who was successful on the merits or otherwise in defense of any
action, suit or proceeding or in defense of any claim, issue or matter in any
proceeding, by reason of such fact as provided in the preceding two sentences
against expenses (including attorneys' fees) actually and reasonably incurred by
him in connection the indemnified claim. A Delaware corporation may pay for the
expenses (including attorneys' fees) incurred by an officer or director in
defending a proceeding in advance of the final disposition to repay the amount
advances if it shall ultimately be determined that he is not entitled to be
indemnified by the corporation.

                                      II-1


         Section 102(b)(7) of the DGCL permits a corporation to provide in its
certificate of incorporation that a director shall not be personally liable to
the corporation or its stockholders for monetary damages for a breach of
fiduciary duty as a director, except for liability (i) for any breach of the
director's duty of loyalty to the corporation or its stockholders, (ii) for any
acts or omissions not in good faith or which involve intentional misconduct or a
knowing violation of law, (iii) in respect of certain unlawful dividend payments
or stock redemptions or repurchases, or (iv) for any transaction from which the
director derived an improper personal benefit. The DGCL permits the purchase of
insurance on behalf of directors and officers against any liability asserted
against directors and officers and incurred by them in their capacity as an
officer or director, or arising out of their status as an officer or director,
whether or not the corporation would have the power to indemnify directors and
officers against that liability. We have acquired officers' and directors'
liability insurance of $1 million for members of our Board of Directors and
executive officers.

         At present, there is no pending litigation or other proceeding
involving any of our directors or officers for which indemnification is being
sought, and we are not aware of any threatened litigation that may result in
claims for indemnification by any officer or director.

         Article Eighth of our certificate of incorporation provides that we
will indemnify all persons we are permitted to indemnify under the Delaware
General Corporation Law, and that this indemnification will be to the fullest
extent permitted the Delaware General Corporation Law.

ITEM 16.  EXHIBITS

         The exhibits listed below have been filed as part of this registration
statement.

         4.1*     Amended and restated certificate of incorporation
                  (incorporated into this registration statement by reference to
                  Exhibit 3.1 to Netrix's registration of Form S-1 filed on
                  September 18, 1992, as amended (File No. 33-50464) (the "1992
                  S-1").
         4.2*     Amended and restated by-laws of Netrix (incorporated into this
                  registration statement by reference to Exhibit 3.2 of
                  the 1992 S-1).
         4.3*     Specimen certificate of common stock of the registrant
                  (incorporated into this registration statement by reference to
                  Exhibit 4.2 to the 1992 S-1).
         4.4*     Certificate of designations for the form of Series A 8%
                  convertible preferred stock.
         4.5*     Supplemental certificate of designations for the form of
                  Series A 8% convertible preferred stock (incorporated by
                  reference to Exhibit 4.2 to Netrix's quarterly report on Form
                  10-Q filed on August 16, 1999, Commission file no.
                  0-50464).
         4.6*     Form of Warrant issued to Renwick Securities, Inc.
                  (incorporated by reference to Exhibit 10.3 to Netrix's
                  quarterly report on Form 10-Q filed on August 16, 1999,
                  Commission file no. 0-50464).
         4.7*     Form of Warrant issued to Coast Business Credit (incorporated
                  by reference to Exhibit 10.2 to Netrix's quarterly report on
                  Form 10-Q filed on August 16, 1999, Commission file
                  no. 0-50464).
         4.8      Amendment to Certificate of Incorporation dated
                  August 26, 1999.
         10.1     Memorandum of Understanding between Netrix Corporation and
                  OpenROUTE Networks, Inc.
          5.1**   Opinion on Legality.
         23.1     Consent of Arthur Andersen LLP.
         23.2**   Consent of Kelley Drye & Warren LLP (contained in
                   Exhibit 5.1).
         24**     Power of Attorney (included within signature page).

         --------------------------------
          *  Incorporated by reference.
         **  Filed previously

                                      II-2



ITEM 17.  UNDERTAKINGS

         The undersigned registrant hereby undertakes:

         A.       To file, during any period in which offers or sales are being
                  made, a post-effective amendment of this registration
                  statement:

                  (i)      To include any prospectus required by Section 10(a)
                           (3) of the Securities Act of 1933.
                  (ii)     To include in the prospectus any facts or events
                           arising after the effective date of the registration
                           statement (or most recent post-effective amendment
                           thereof) which, individually or in the aggregate,
                           represent a fundamental change in the information set
                           forth in the registration statement.
                  (iii)    To include any material information with respect to
                           the plan of distribution not previously disclosed in
                           the registration statement or any material change to
                           such information in the registration statement.

         B.       That, for the purposes of determining any liability under the
                  Securities Act of 1933, each such post-effective amendment
                  shall be deemed to be a new registration statement relating to
                  the securities offered therein, and the offering of such
                  securities at that time shall be deemed to be the initial bona
                  fide offering thereof.

         C.       To remove from registration by means of post-effective
                  amendment any of the securities registered which remain unsold
                  at the termination of the offering.

         D.       Insofar as indemnification for liabilities arising under the
                  Securities Act of 1933 may be permitted to directors,
                  officers and controlling persons of the registrant pursuant to
                  any charter provisions, by-laws, contract, arrangements,
                  statute or otherwise, the registrant has been advised that in
                  the opinion of the Securities and Exchange Commission such
                  indemnification is against public policy as expressed in the
                  Act and is, therefore, unenforceable.  In the event that a
                  claim for indemnification against such liabilities (other than
                  the payment by the registrant of expenses incurred or paid by
                  a director, officer or controlling person of the registrant of
                  expenses incurred or paid by a director, officer or
                  controlling person of the registrant in the successful defense
                  of any action, suit, or proceeding) is asserted by such
                  director, officer or controlling person in connection with
                  the securities being registered, the registrant will, unless
                  in the opinion of its counsel the matter has been settled by a
                  controlling precedent, submit to a court of appropriate
                  jurisdiction the question whether such indemnification by it
                  is against public policy as expressed in the Act and will be
                  governed by the final adjudication of such issue.

         E.       Subject to the terms and conditions of Section 15(d) of the
                  Securities Exchange Act of 1934, as amended, Netrix
                  Corporation hereby undertakes to file with the Securities and
                  Exchange Commission such supplementary and periodic
                  information, documents and reports as may be prescribed by any
                  rule or regulation of the Commission heretofore or hereafter
                  duly adopted pursuant to authority conferred in that Section.



                                      11-3





                                   SIGNATURES

         In accordance with the requirements of the Securities Act of 1933, as
amended, Netrix Corporation certifies that it has reasonable grounds to believe
that it meets all of the requirements for filing on Form S-3 and authorizes this
registration statement to be signed on its behalf by the undersigned, in the
City of Herndon, State of Virginia, on September 8, 1999.

                                                 NETRIX CORPORATION

                                                 By: /s/ Steven T. Francesco
                                                    ____________________________
                                                     Steven T. Francesco
                                                     Chief Executive Officer

         In accordance with the requirements of the Securities Act of 1933, this
amendment to the registration statement has been signed by the following persons
in the capacities and on the date indicated.






SIGNATURE                                                         TITLE                                DATE
- ---------                                                         -----                                ----
                                                                               


                                                       Chief Executive Officer and
 /s/ Steven T. Francesco                            Chairman of the Board of Directors          September 8, 1999
- -------------------------------------------            Principal Executive Officer)
Steven T. Francesco


/s/ Lynn C. Chapman                                 President, Chief Operating Officer          September 8, 1999
- -------------------------------------------                and Director
Lynn C. Chapman


/s/ Peter J. Kendrick                           Vice President-Finance and Administration       September 8, 1999
- -------------------------------------------              and Chief Financial Officer
Peter J. Kendrick                               (Principal Financial and Accounting Officer)



                                                                 Director                       September 8, 1999
- -------------------------------------------
Gregory McNulty


/s/ John M. Faccibene*                                           Director                       September 8, 1999
- -------------------------------------------
John M. Faccibene


/s/ Richard Yalen*                                               Director                       September 8, 1999
- -------------------------------------------
Richard Yalen


/s/ Douglas J. Mello*                                            Director                       September 8, 1999
- -------------------------------------------
Douglas J. Mello


* By Steven T. Francesco, attorney-in-fact.



                                      11-4



     ITEM 27. EXHIBITS

              (a) The exhibits listed below have been filed as part of this
                  registration statement.

      EXHIBIT NO.                   DESCRIPTION
      -----------                   -----------


         The exhibits listed below have been filed as part of this registration
statement.

         4.1*     Amended and restated certificate of incorporation
                  (incorporated into this registration statement by reference to
                  Exhibit 3.1 to Netrix's registration of Form S-1 filed on
                  September 18, 1992, as amended (File No. 33-50464) (the "1992
                  S-1").
         4.2*     Amended and restated by-laws of Netrix (incorporated into this
                  registration statement by reference to Exhibit 3.2 of
                  the 1992 S-1).
         4.3*     Specimen Certificate of common stock of the registrant
                  (incorporated into this registration statement by reference to
                  Exhibit 4.2 to the 1992 S-1).
         4.4*     Certificate of designations for the form of Series A 8%
                  convertible preferred stock.
         4.5*     Supplemental certificate of designations for the form of
                  Series A 8% convertible preferred stock (incorporated into
                  this registration statement by reference to Exhibit 4.2 to
                  Netrix's quarterly report on Form 10-Q filed on August 16,
                  1999, Commission file no. 0-50464).
         4.6*     Form of warrant issued to Renwick Securities, Inc.
                  (incorporated into this registration statement by reference to
                  Exhibit 10.3 to Netrix Corporation's quarterly report on Form
                  10-Q filed on August 16, 1999, Commission file no.
                  0-50464).
         4.7*     Form of warrant issued to Coast Business Credit (incorporated
                  into this registration statement by reference to Exhibit 10.2
                  to Netrix's quarterly report on Form 10-Q filed on August 16,
                  1999, Commission file no. 0-50464).
         4.8      Amendment to Certificate of Incorporation dated August 26,
                  1999.
         5.1**    Opinion on Legality.
         10.1     Memorandum of Understanding between Netrix Corporation and
                  OpenROUTE Networks, Inc.
         23.1     Consent of Arthur Andersen LLP.
         23.2**   Consent of Kelley Drye & Warren LLP (contained in
                   Exhibit 5.1).
         24**     Power of attorney (included within signature page).
     ---------------
          *Incorporated by reference
         **Filed previously