EX-99.906CERT

Section 906 Certifications


                CERTIFICATION PURSUANT TO 18 U.S.C SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002


John V. Murphy, Principal Executive Officer, and Brian W. Wixted, Principal
Financial Officer, of Oppenheimer Series Fund, Inc. (the "Registrant"), each
certify to the best of his knowledge that:

1. The Registrant's  periodic report on Form N-CSR for the period ended April
   30,  2006 (the "Form  N-CSR")  fully  complies  with the  requirements  of
   Section 15(d) of the Securities Exchange Act of 1934, as amended; and

2. The  information  contained  in the Form  N-CSR  fairly  presents,  in all
   material  respects,  the financial  condition and results of operations of
   the Registrant.  This  certification  is being furnished to the Commission
   solely  pursuant  to 18 U.S.C.  ss. 1350 and is not being filed as part of
   the Form N-CSR filed with the Commission.


Principal Executive Officer             Principal Financial Officer

Oppenheimer Series Fund, Inc.           Oppenheimer Series Fund, Inc.


/s/ JOHN V. MURPHY                      /s/ BRIAN W. WIXTED
- ----------------------------             ----------------------------
John V. Murphy                          Brian W. Wixted

Date: June 15, 2006                     Date: June 15, 2006