EXHIBIT 21.1

                              List of Subsidiaries


<Table>
<Caption>
Name                                              Jurisdiction of Incorporation
- ----                                              -----------------------------
                                               
Discovery Partners International AG                       Switzerland

ChemRx Advanced Technologies, Inc.                        Delaware

Structural Proteomics, Inc.                               New Jersey

Systems Integration Drug Discovery Company, Inc.          Arizona

Xenometrix, Inc.                                          Delaware

Irori Europe, Ltd.                                        United Kingdom
</Table>