1 SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-A/A AMENDMENT NO. 1 FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 LIGAND PHARMACEUTICALS INCORPORATED (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER) Delaware 77-0160744 (STATE OF INCORPORATION (I.R.S. EMPLOYER OR ORGANIZATION) IDENTIFICATION NO.) 10275 Science Center Drive 92121 San Diego, California (ZIP CODE) (ADDRESS OF PRINCIPAL EXECUTIVE OFFICES) If this form relates to the If this form relates to the registration of a class of securities registration of a class of pursuant to Section 12(b) of the securities pursuant to Section Exchange Act and is effective 12(g) of the Exchange Act and is pursuant to General Instruction A(c) to become effective pursuant to please check the following box. [ ] General Instruction A(d) please check the following box. [ ] SECURITIES TO BE REGISTERED PURSUANT TO SECTION 12(b) OF THE ACT: TITLE OF EACH NAME OF EACH EXCHANGE ON CLASS TO BE SO WHICH EACH CLASS IS TO BE REGISTERED REGISTERED Not Applicable Not Applicable SECURITIES TO BE REGISTERED PURSUANT TO SECTION 12(g) OF THE ACT: PREFERRED SHARE PURCHASE RIGHTS (TITLE OF CLASS) 2 The undersigned hereby amends Items 1 and 2 of its Registration Statement on Form 8-A, dated September 30, 1996 (the "Registration Statement"), as set forth below. ITEM 1. Description of Registrant's Securities to be Registered. The Board of Directors of Ligand Pharmaceuticals Incorporated, a Delaware corporation (the "Company"), approved an amendment (the "Amendment"), dated as of November 9, 1998, to the Preferred Shares Rights Agreement, dated as of September 13, 1996, by and between the Company and ChaseMellon Shareholder Services, L.L.C. (the successor rights agent to Wells Fargo Bank N.A.), as Rights Agent (the "Rights Agreement"). All capitalized terms used below and not defined herein have the meanings given them in the Rights Agreement. The Amendment provides that neither Elan Corporation, plc, a public limited company organized under the laws of Ireland ("Elan"), nor Elan International Services, Ltd., a Bermuda corporation ("EIS"), nor any affiliates of Elan or EIS shall be deemed to be an Acquiring Person by virtue of (i) their beneficial ownership on or before November 9, 2005 of an aggregate of up to twenty-five percent (25%) of the outstanding capital stock of the Company on a fully diluted basis or (ii) their beneficial ownership after November 9, 2005 of a percentage of the then outstanding Common Shares, equal to the percentage of the then outstanding Common Shares of the Company beneficially owned by Elan, EIS and their respective Affiliates on November 9, 2005, to the extent their beneficial ownership exceeds 20% on such date. In determining whether Elan, EIS or any of their respective Affiliates shall be deemed to be an Acquiring Person, shares of Common Stock that are beneficially owned by such Person and acquired pursuant to the Securities Purchase Agreement, entered into as of November 6, 1998, between the Company, Elan and EIS, as it may be amended or supplemented from time to time (the "Securities Purchase Agreement"), the Development, Licence and Supply Agreement, entered into as of November 9, 1998, between the Company and Elan, as it may be amended or supplemented from time to time (the "License Agreement") and the Stock Purchase Agreement entered into as of September 30, 1998, between the Company and EIS, as it may be amended or supplemented from time to time (the "Stock Purchase Agreement" and collectively with the Securities Purchase Agreement and the License Agreement, the "Elan Agreements"), or upon conversion of the Company's Zero Coupon Convertible Senior Notes due 2008 (the "Notes"), or which are beneficially owned as a result of the ownership of the Notes shall not be counted unless Elan, EIS or their respective Affiliates shall beneficially own additional Shares of Common Stock that are acquired other than pursuant to the Elan Agreements or the Notes. The foregoing description of the Amendment is qualified in its entirety by reference to the full text of the Amendment, which is filed as Exhibit 99.1 hereto and is incorporated herein by reference. ITEM 2. Exhibits. EXHIBIT NUMBER DESCRIPTION - ------ ----------- 99.1 Amendment, dated as of November 9, 1998, between Ligand Pharmaceuticals Incorporated and ChaseMellon Shareholder Services, L.L.C., as Rights Agent. 3 SIGNATURE Pursuant to the requirements of Section 12 of the Securities Exchange Act of 1934, the registrant has duly caused this registration statement to be signed on its behalf by the undersigned, thereto duly authorized. LIGAND PHARMACEUTICALS INCORPORATED Date: November 10, 1998 ---------------------------------- By: /s/ Paul V. Maier ---------------------------------- Paul V. Maier, Senior Vice President, Chief Financial Officer 4 EXHIBIT INDEX EXHIBIT NUMBER DESCRIPTION - ------ ----------- 99.1 Amendment, dated as of November 9, 1998, between Ligand Pharmaceuticals Incorporated and ChaseMellon Shareholder Services, L.L.C., as Rights Agent.