. . . EXHIBIT 3.1 [BRITISH COLUMBIA LOGO] MINISTRY OF FINANCE MAILING ADDRESS: LOCATION: Corporate and Personal PO BOX 9431 Stn Prov Govt 2nd Floor - 940 Blanshard St Property Registries Victoria BC V8W 9V3 Victoria BC 250 356-8626 www.corporateonline.gov.bc.ca ================================================================================ NOTICE OF ARTICLES CERTIFIED COPY Of a Document filed BUSINESS CORPORATIONS ACT with the Province of British Columbia Registrar of Companies /s/ J S Powell J S Powell November 19, 2004 This Notice of Articles was issued by the Registrar on: November 19, 2004 10:17 AM Pacific Time Incorporation Number: C0709000 Recognition Date and Time: Continued into British Columbia on November 19, 2004 10:17 AM Pacific Time NOTICE OF ARTICLES NAME OF COMPANY: ASPREVA PHARMACEUTICALS CORPORATION REGISTERED OFFICE INFORMATION MAILING ADDRESS: DELIVERY ADDRESS: 25TH FLOOR, TORONTO-DOMINION BANK TOWER 25TH FLOOR, 700 WEST GEORGIA STREET P.O. BOX 10026, 700 WEST GEORGIA STREET VANCOUVER BC V7Y 1B3 VANCOUVER BC V7Y 1B3 RECORDS OFFICE INFORMATION MAILING ADDRESS: DELIVERY ADDRESS: 25TH FLOOR, TORONTO-DOMINION BANK TOWER 25TH FLOOR, 700 WEST GEORGIA STREET P.O. BOX 10026, 700 WEST GEORGIA STREET VANCOUVER BC V7Y 1B3 VANCOUVER BC V7Y 1B3 C0709000 Page: 1 of 3 DIRECTOR INFORMATION LAST NAME, FIRST NAME MIDDLE NAME: Hunt, Ronald MAILING ADDRESS: DELIVERY ADDRESS: 11 MADISON AVENUE, 26TH FLOOR 11 MADISON AVENUE, 26TH FLOOR NEW YORK NY 10010 NEW YORK NY 10010 UNITED STATES UNITED STATES LAST NAME, FIRST NAME MIDDLE NAME: Hayden, Dr. Michael MAILING ADDRESS: DELIVERY ADDRESS: 4484 WEST 7TH AVENUE 4484 WEST 7TH AVENUE VANCOUVER BC V6R 1W9 VANCOUVER BC V6R 1W9 LAST NAME, FIRST NAME MIDDLE NAME: Hall, Noel MAILING ADDRESS: DELIVERY ADDRESS: 5077 CORDOVA BAY ROAD 5077 CORDOVA BAY ROAD VICTORIA BC V8Y 2K1 VICTORIA BC V8Y 2K1 LAST NAME, FIRST NAME MIDDLE NAME: Glickman, Richard MAILING ADDRESS: DELIVERY ADDRESS: 2377 TRYON ROAD 2377 TRYON ROAD SIDNEY BC V8L 5H8 SIDNEY BC V8L 5H8 LAST NAME, FIRST NAME MIDDLE NAME: MacKay-Dunn, R. Hector MAILING ADDRESS: DELIVERY ADDRESS: 1606 LAURIER AVENUE 1606 LAURIER AVENUE VANCOUVER BC V6J 2Y4 VANCOUVER BC V6J 2Y4 C0709000 Page: 2 of 3 LAST NAME, FIRST NAME MIDDLE NAME: Oronsky, Arnold MAILING ADDRESS: DELIVERY ADDRESS: 2710 SANDHILL ROAD, 2ND FLOOR 2710 SANDHILL ROAD, 2ND FLOOR MENLO PARK CA 94025 MENLO PARK CA 94025 UNITED STATES UNITED STATES AUTHORIZED SHARE STRUCTURE 1 . No Maximum Common Shares Without Par Value With Special Rights or Restrictions attached 2. No Maximum Preferred Shares Without Par Value With Special Rights or Restrictions attached 1) 9,873,204 Series A, Preferred Special Rights or Restrictions are attached C0709000 Page: 3 of 3 [BRITISH COLUMBIA LOGO] MINISTRY OF FINANCE Mailing Address: APPLICATION TO CORRECT Corporate and Personal PO Box 9431 Stn Prov Govt THE CORPORATE REGISTER Property Registries Victoria BC V8W 9V3 FORM 47 www.fin.gov.bc.ca/registries Location: 2nd Floor - 940 Blanshard Street Victoria BC Telephone: 250 356-8626 INSTRUCTIONS: PLEASE TYPE OR PRINT CLEARLY IN BLOCK LETTERS AND FREEDOM OF INFORMATION AND PROTECTION OF ENSURE THAT THE FORM IS SIGNED AND DATED IN INK. PRIVACY ACT (FIPPA): The personal information requested on this form is made The Application to Correct the Corporate Register available to the public under the form is to be used to correct some types of authority of the Business Corporations information in a record that was filed with the Act. Questions about how the FIPPA applies registrar. to this personal information can be directed to the Administrative Assistant FUTURE EFFECTIVE DATES: If a record has a future of the Corporate and Personal Property effective date and an error is found before the Registries at 250 356-1198, PO Box 9431 specified date and time of the filing, the record Stn Prov Govt, Victoria BC V8W 9V3. must be withdrawn, corrected and re-filed. Please visit our Web site at www.fin.gov.bc.ca/registries or OFFICE USE ONLY - DO NOT WRITE IN THIS AREA phone 250 356-8626 for information on how to file these notices. ITEM B Enter the name exactly as shown on the Certificate of Incorporation, Registration, Amalgamation, Continuation, or Change of Name. ITEM C Indicate the record to be amended and the date and time that record was filed. Enter the reason for the amendment including what the record stated at the time of filing. For example: Notice of Change of Directors, filed November 23, 2004, Director's name spelled incorrectly - John Smith should have read John Smythe. ITEM D If the applicant is a corporation or firm, enter the full name of the corporation or firm. ITEM E The applicant must be an authorized signing authority for the company. If the applicant is a corporation or firm, this form must be signed by an authorized signing authority for that corporation or firm. FILING FEE: $20.00 Submit this form with a cheque or money order made payable to the Minister of Finance, or provide the registry with authorization to debit the fee from your BC OnLine Deposit Account. Please pay in Canadian dollars or in the equivalent amount of US funds. - -------------------------------------------------------------------------------- A INCORPORATION/REGISTRATION NUMBER OF CORPORATION C-0709000 - -------------------------------------------------------------------------------- B NAME OF CORPORATION ASPREVA PHARMACEUTICALS CORPORATION - -------------------------------------------------------------------------------- C RECORD TO BE AMENDED Name of Record to be Amended: Continuation Application YYYY / MM / DD Filed Date: 2004 / 11 / 19 and Time 10:17 [X]a.m. or [ ]p.m. Pacific Time Reason for Amendment: - -------------------------------------------------------------------------------- D FULL NAME OF APPLICANT LAST NAME FIRST NAME MIDDLE NAME CORPORATION OR FIRM NAME ASPREVA PHARMACEUTICALS CORPORATION - -------------------------------------------------------------------------------- E CERTIFIED CORRECT - I have read this form and found it to be correct. NAME OF APPLICANT SIGNATURE OF APPLICANT DATE SIGNED R. Hector MacKay-Dunn, /s/ R. HECTOR MACKAY-DUNN YYYY / MM / DD Corporation Secretary 2004 / 12 / 02 - -------------------------------------------------------------------------------- SCHEDULE "A" TO FORM 47 - APPLICATION TO CORRECT THE CORPORATE REGISTER OF ASPREVA PHARMACEUTICALS CORPORATION (C-0709000) (THE "COMPANY") On November 19, 2004 at 10:17 am the Company filed a Continuation Application which contained incorrect information as to the directors of the Company at the time of continuance. Namely, that R. Hector MacKay-Dunn was inadvertently included as a director of the Company; however, he resigned as a director of the Company effective September 30, 2004 and should not have been included. In addition, Kirk Calhoun, George Milne and William Hunter were appointed directors of the Company effective September 30, 2004 and their respective names and addresses were inadvertently omitted from the Continuation Application at the time of filing. Consequently, the Company hereby wishes to amend the director information stated in the Continuation Application by: (a) removing R. Hector MacKay-Dunn as a director of the Company, and (b) adding the following directors: (i) Kirk Calhoun, 201 Ocean Ave B1004, Santa Monica, CA 90402 (ii) Dr. George Milne, PO Box 473, 4049 Shore Lane, Boca Grande, FL 33921 (iii) Dr. William Hunter, 1618 Station Street, Vancouver, BC V6A 1B6 Following the above-noted amendment, the directors of the Company at the time of filing the Continuation Application are as set out in Appendix 1 attached hereto and the Company requests that you correct your Corporate Register to reflect same. APPENDIX 1 TO SCHEDULE "A" OF FORM 47 - APPLICATION TO CORRECT THE CORPORATE REGISTER OF ASPREVA PHARMACEUTICALS CORPORATION (C-0709000) (THE "COMPANY") LIST OF DIRECTORS FULL NAME RESIDENTIAL ADDRESS - ------------------- ----------------------------- Richard M. Glickman 2377 Tryon Road Sidney, BC V8L 5H8 Noel Hall 5077 Cordova Bay Road Victoria, BC V8Y 2K1 Dr. Michael Hayden 4484 West 7th Avenue Vancouver, BC V6R 1W9 Ronald M. Hunt 11 Madison Avenue 26th Floor New York, New York, USA 10010 Arnold Oronsky 2710 Sand Hill Road 2nd Floor Menlo Park, CA, USA 94025 Kirk Calhoun 201 Ocean Ave B1004 Santa Monica, CA, USA 90402 Dr. George Milne 30 Bishops Bay Drive Niantic, CT, USA 06357-2755 Dr. William Hunter 1618 Station Street Vancouver, BC V6A 1B6