FORM OF WARRANT - 2003
                                                                     EXHIBIT 4.5

THE SECURITIES  REPRESENTED HEREBY HAVE NOT BEEN REGISTERED UNDER THE SECURITIES
ACT OF 1933 OR APPLICABLE  STATE  SECURITIES  LAWS.  THESE  SECURITIES HAVE BEEN
ACQUIRED FOR INVESTMENT  AND NOT WITH A VIEW TO  DISTRIBUTION  OR RESALE.  THESE
SECURITIES MAY NOT BE OFFERED FOR SALE, SOLD, DELIVERED AFTER SALE, TRANSFERRED,
PLEDGED OR  HYPOTHECATED IN THE ABSENCE OF AN EFFECTIVE  REGISTRATION  STATEMENT
COVERING SUCH SECURITIES UNDER THE ACT AND ANY APPLICABLE STATE SECURITIES LAWS,
UNLESS THE HOLDER SHALL HAVE OBTAINED AN OPINION OF COUNSEL  SATISFACTORY TO THE
COMPANY THAT SUCH REGISTRATION IS NOT REQUIRED.



                  NOT NEGOTIABLE AND RESTRICTED TRANSFERABILITY
                        WARRANT TO PURCHASE COMMON STOCK
                                       OF
                           HEMISPHERx BIOPHARMA, INC.

Date: _________________, 2003                                     No. 03-XX-XX


         Hemispherx  Biopharma,  Inc., a Delaware  corporation  (the "Company"),
hereby  certifies  that, for value received,  ___________________  (the "Warrant
Holder"),  is entitled to subscribe for and purchase up to ______________ shares
of the Company's Common Stock at a price equal to the "Exercise Price",  subject
to the provisions and upon the terms and conditions  hereinafter set forth. This
warrant and related terms were approved by the Board of Directors.

         This  Warrant is subject to all of the terms and  conditions  specified
below.

          1.   Common  Stock.  The Common Stock of  Hemispherx  Biopharma,  Inc.
               which  at  the  date  hereof   consists  of  100  million  shares
               authorized,  each share having a par value of $.001 per share, as
               designated  in the  Company's  Certificate  of  Incorporation  as
               amended from time to time.

          2.   Stock   Purchasable.   The  number  of  shares  of  Common  Stock
               purchasable   upon  the  total   exercise  of  this   Warrant  is
               ________________________ (______________).

          3.   Exercise  Price.  The price at which this Warrant is exercisable,
               unless  such  price is  adjusted  as  described  in Section 7, is
               $_______  per  share,  in lawful  funds of the  United  States of
               America ("Exercise Price").

          4.   Expiration of Warrant. This Warrant shall expire and be no longer
               exercisable  after 5:00 p.m.  Eastern Time on  __________________
               (Expiration Date").

          5.   Exercise of Warrants.  Except for an event of the immediate right
               to exercise as set forth below,  these  warrants may be exercised
               as of September 10, 2003 and thereafter during the remaining term
               of this agreement.  All warrants shall be exercisable immediately
               upon  the  merger  of  the  Company  into  another  entity,   the
               acquisition  of the Company by another  entity or  disposition of
               all or a substantial  portion of the Company's  assets to another
               entity  not  controlled  by  the  Company.  The  purchase  rights
               represented  by this Warrant may be exercised,  as allowed by the
               terms and conditions of this agreement,  in whole or in part (but
               not less than 1,000 share  increments),  by the  Warrantholder or
               its duly authorized  attorney or  representative  at any time and
               from  time  to time  while  this  Warrant  is  exercisable,  upon
               presentation  of this  Warrant  at the  principal  office  of the
               Company,  with the purchase form attached  hereto duly  completed
               and  signed,  and  upon  payment  to the  Company  in  cash or by
               certified check or bank draft of an amount equal to the number of
               shares  being so  purchased  multiplied  by the  Exercise  Price.
               Should  Warrantholder  elect to so surrender  this Warrant,  This
               Warrant shall be terminated  thereafter,  and Warrantholder shall
               have no other rights hereunder.

               If,during the five-year period after
               the date of this Agreement, the
               Company  proposes to register  any of its common  stock (or other
               security  into  which the  common  stock has been  recapitalized,
               converted  or  transformed)  with  the  Securities  and  Exchange
               Commission (other than  registrations  involving only acquisition
               transactions  or benefit  plans),  the Company  will use its best
               efforts to  register,  at its own  expense  (except  for  selling
               commissions)  under the Securities  Act of 1933, as amended,  and
               laws of the various states as may be required, the Stock so as to
               permit the sales of securities issuable upon the exercise of this
               Warrant to be lawful under such laws. The Company shall indemnify
               the  Warrantholder  and  any  transferee  with  respect  to  such
               registration statement.

          6.   Procedures.  The Company agrees that the  Warrantholder  shall be
               deemed the record  owner of the Stock as of the close of business
               on the date on which the Warrant  shall have been  presented  and
               payment  shall  have  been  made  for  the  Stock  as  aforesaid.
               Certificates  for the  shares  of  Stock  so  purchased  shall be
               delivered  to the  Warrantholder  within a reasonable  time,  not
               exceeding  15 days,  after  the  exercise  in full of the  rights
               represented by this Warrant.

               If the Warrant is exercised  in  part  only,  the  Company,  upon
               surrender of this Warrant for  cancellation,  shall deliver a new
               Warrant  evidencing the rights of the  Warrantholder  to purchase
               the  balance of the shares of Stock  which the  Warrantholder  is
               entitled to purchase hereunder.

          7.   Adjustment of Exercise  Price and Number of Warrant  Shares.  The
               number and kind of  securities  purchasable  upon the exercise of
               this  Warrant  and  the  Exercise   Price  shall  be  subject  to
               adjustment  from  time to time  upon the  occurrence  of  certain
               events and in the manner described below.

          (a)  Reorganization,  Consolidation,  Merger,  etc.  In  case  of  any
               capital    reclassification   or   reorganization   or   of   any
               consolidation  or  merger of the  Company  with or into any other
               person,  or any  other  corporate  reorganization  (other  than a
               merger  or  consolidation  in  which  the  Company  shall  be the
               continuing  or surviving  entity and which does not result in any
               change in the Common  Stock) or any sale of all or  substantially
               all of the  assets of the  Company  (any such  transaction  being
               hereinafter  referred to as a  "Reorganization"),  then,  in each
               case,  the  Holder,  on  exercise  hereof  at any time  after the
               consummation  or  effective  date  of  such  Reorganization  (the
               "Effective Date"),  shall receive,  in lieu of the Warrant Shares
               issuable on such exercise prior to the Effective  Date, the stock
               and other securities and property  (including cash) to which such
               Holder would have been  entitled  upon the  Effective  Date as if
               this  Warrant  were fully  vested and Holder had  exercised  this
               Warrant immediately prior thereto.

          (b)  Split, Subdivision or Combination of Common Stock. If the Company
               at any time while this Warrant remains  outstanding  shall split,
               subdivide  or combine the Common  Stock or shall issue a dividend
               on the  Common  Stock  payable  in shares of  Common  Stock,  the
               Exercise Price shall be proportionately  decreased in the case of
               a split, subdivision or stock dividend, and increased in the case
               of a combination.

          (c)  Other Dividends and  Distributions.  If the Company shall make or
               issue,  or shall  fix a  record  date  for the  determination  of
               eligible  holders  entitled  to  receive,  a  dividend  or  other
               distribution  with  respect  to the Common  Stock  payable in (i)
               securities  or  evidences  of  indebtedness  of the Company or of
               other  persons  (other than shares of Common  Stock in which case
               the provisions of paragraph (b) above shall apply) or (ii) assets
               or cash  (excluding  cash dividends paid or payable solely out of
               retained  earnings),  then in each case,  the Holder on  exercise
               hereof at any time  after  the  consummation,  effective  date or
               record  date of such  event,  shall  receive,  in addition to the
               Warrant  Shares (or such other stock or  securities)  issuable on
               such  exercise  prior to such dates the  securities or such other
               assets of the Company to which  Holder  would have been  entitled
               upon such date as if this  Warrant  were fully  vested and Holder
               has exercised this Warrant immediately prior thereto.

          (d)  Adjustment  of Number of  Shares.  Upon  each  adjustment  in the
               Exercise  Price,   the  number  of  Warrant  Shares   purchasable
               hereunder  shall be adjusted,  to the nearest whole share, to the
               product  obtained  by  multiplying  the number of Warrant  Shares
               purchasable  immediately prior to such adjustment in the Exercise
               Price by a  fraction  (i) the  numerator  of  which  shall be the
               Exercise Price immediately prior to such adjustment, and (ii) the
               denominator  of which  shall be the  Exercise  Price  immediately
               after such adjustment.

          (e)  Statements of  Adjustments.  Whenever the Exercise Price shall be
               adjusted as provided in this Section 7, the Company shall prepare
               a statement  showing the facts  requiring such adjustment and the
               Exercise Price that shall be in effect after such adjustment. The
               Company shall cause a copy of such statement to be by first class
               mail, postage prepaid, to the Holder at his/her address appearing
               on the Company's  records.  Where  appropriate,  such copy may be
               given  in  advance  and may be  included  as  part of the  notice
               required to be mailed under the  provisions of subsection  (g) of
               this Section 7.

          (f)  Effectiveness   of  Adjustment.   Adjustment   made  pursuant  to
               subsection (b) (c) and (d) of this Section 7 shall be made on the
               date  such   split,   subdivision,   dividend,   combination   or
               distribution,  as the  case  may be is  made,  and  shall  become
               effective  at the opening of business  on the  business  day next
               following the record date for the  determination  of stockholders
               entitled to such split,  subdivision,  dividend,  combination  or
               distribution.


          (g)  Notices.  In the  event the  Company  shall  propose  to take any
               action of the types  described  in  subsection  (a) (b) or (c) of
               this Section 7, the Company  shall give notice to the Holder,  in
               the manner set forth in  subsection  (e) of this Section 7, which
               notice shall specify the record date, if any, with respect to any
               such  action and the date on which such  action is to take place.
               Such notice shall also set forth such facts with respect  thereto
               as shall be reasonably  necessary to indicate the number, kind or
               class of shares or other  securities  or property  which shall be
               deliverable  to the Holder upon  exercise  hereof  following  the
               occurrence of such action.  In the case of any action which would
               require the fixing of a record date,  such notice  shall,  to the
               extent practicable be given at least 10 days prior to the date so
               fixed,  and in case of all other  action,  such  notice  shall be
               given at  least 10 days  prior  to the  taking  of such  proposed
               action. Failure to give such notice, or any defect therein, shall
               not affect the legality or validity of any such action.

          (h)  Other Adjustments. In case at any time conditions arise by reason
               of action taken by the Company (expressly  excluding the grant of
               stock  options  to  employees  and the  grant of  warrants  at an
               exercise  price not less than  fair  market  value on the date of
               grant),  which in the opinion of its Board of  Directors  are not
               adequately  covered by the other provisions of this Section 7 and
               which would  materially  and  adversely  affect the rights of the
               Holder,  then  the  Board  of  Directors  may  appoint  a firm of
               independent  certified public accountants of recognized  national
               standing (who may be the  accountants  then auditing the books of
               the  Company)  to advise  on the  adjustment  if any,  on a basis
               consistent with the standards established in the other provisions
               of this Section 7,  necessary  with respect to the Exercise Price
               and  number  of  Warrant  Shares,  as  so  to  preserve,  without
               dilution,  the rights of the Holder  hereunder.  Upon  receipt of
               such  report,  the  Board  shall  have  the  power  to  make  the
               adjustments, if any, it deems appropriate.

          8.   Covenants. The Company covenants and agrees that:

          (a)  Reservation  of Stock.  During the period within which the rights
               represented  by the Warrant may be exercised,  the Company shall,
               at all times,  reserve and keep  available,  free from preemptive
               rights out of the aggregate of its authorized but unissued Stock,
               for the purpose of enabling it to satisfy any obligation to issue
               shares of Stock upon the exercise of this Warrant,  the number of
               shares of Stock deliverable upon the exercise of this Warrant. If
               at any time the number of shares of authorized Stock shall not be
               sufficient  to effect the exercise of this  Warrant,  the Company
               shall take such corporate  action as may be necessary to increase
               its  authorized  but  unissued  Stock to such number of shares as
               shall be  sufficient  for such  purpose.  The Company  shall have
               analogous  obligations  with respect to any other  securities  or
               properties issuable upon exercise of this Warrant.


          (b)  No Liens,  etc. All Stock that may be issued upon exercise of the
               rights  represented  by this Warrant  shall,  upon  issuance,  be
               validly  issued,  fully  paid,  nonassessable  and free  from all
               taxes, liens and charges with respect to the issue thereof;

          (c)  Taxes.  All  original  issue taxes  payable  with  respect to the
               issuance of shares upon the exercise of the rights represented by
               this Warrant shall be borne by the Company, but in no event shall
               the Company be responsible or liable for income taxes or transfer
               taxes upon the transfer of any Warrant;

          (d)  No Diminution of Value.  The Company shall not take any action to
               terminate this Warrant or to diminish it in value; and

          (e)  Notice of Events.  The Company shall give prior written notice to
               the  Warrantholder of (i) any tender offer that is being made for
               any of the Company's  stock;  (ii) any offers to holders of Stock
               for  subscription  or  purchase by them of any shares of stock of
               any  class;  (iii) any  capital  reorganization  of the  Company,
               reclassification   of  the   capital   stock   of  the   Company,
               consolidation  or  merger  of the  Company  with or into  another
               corporation,  the sale, lease or transfer of all or substantially
               all  of  the  property  or  assets  of  the  Company  to  another
               corporation   or  the  voluntary  or   involuntary   dissolution,
               liquidation  or winding up of the  Company  and (iv) any event of
               the type  described  in  Section  7 hereof  (all  such  events in
               clauses  (i)-(iv)  above  are  referred  to  as  "Events").  Upon
               becoming  aware of any  pending or  proposed  Event,  the Company
               shall  deliver  notice at least five business days before the day
               of the occurrence of any Event and shall describe the Event,  the
               date it is to take place and when the  holders  of the  Company's
               stock will be entitled to exchange their shares for securities or
               other properties deliverable upon such Event.

          9.   Voting Rights.  Until  exercised,  this Warrant shall not entitle
               the  Warrantholder  to any  voting  rights  or other  rights as a
               stockholder of the Company.

          10.  Transfer   Restrictions.   A   Warrantholder   may  transfer  its
               beneficial interest or any portion thereof in the Warrant only to
               the Warrantholder's  spouse, lineal descendants or ancestors (and
               their  spouses)  or the  trustee  of a trust  for  the  principal
               benefit of such persons.  Any transfer of ownership or control of
               a corporation or other entity which is a  Warrantholder  shall be
               deemed a transfer  of this  Warrant  which must  comply  with the
               terms of this Section 10. In  addition,  neither this Warrant nor
               the  Stock  issuable  upon  the  exercise  hereof  may  be  sold,
               transferred,  pledged or  hypothecated  unless the Company  shall
               have been supplied with evidence  reasonably  satisfactory  to it
               that such  transfer is not  violation  of the  Securities  Act of
               1933, as amended (the "Act"),  and any applicable state laws. The
               Company may place a legend to that effect on this  Warrant or any
               replacement  Warrant and on each certificate  representing shares
               issuable  upon   exercise  of  this   Warrant.   Subject  to  the
               satisfaction  of the aforesaid  condition,  this Warrant shall be
               transferable by the Warrantholder.

               If this Warrant is transferred,in whole or in part,upon surrender
               of this Warrant to the Company, the Company shall deliver to each
               transferee a Warrant  evidencing the rights of such transferee to
               purchase  the number of shares of Stock that such  transferee  is
               entitled to purchase pursuant to such transfer.

          11.  Stockholder  Communications.  Until the exercise or expiration of
               this Warrant,  the Company shall provide each  Warrantholder with
               each and  every  report  or  other  communication  mailed  to the
               stockholders of the Company.

          12.  Lost, Stolen Warrants.  If this Warrant is lost, stolen mutilated
               or destroyed, the Company shall, on such terms as the Company may
               reasonably impose, including a requirement that the Warrantholder
               obtain a bond,  issue a new Warrant of like  denomination,  tenor
               and date.  Any such new  Warrant  shall  constitute  an  original
               contractual  obligation  of  the  Company,  whether  or  not  the
               allegedly lost,  stolen,  mutilated or destroyed Warrant shall be
               at any time enforceable by anyone.

          13.  Provisions of New Warrants.  Any Warrant  issued  pursuant to the
               provisions of Section 14, or upon transfer, exchange, division or
               partial  exercise of this  Warrant or  combination  thereof  with
               another  Warrant or Warrants,  shall set forth each provision set
               forth in Sections 1 through  26,  inclusive,  of this  Warrant as
               each  such  provision  is set  forth  herein,  and  shall be duly
               executed on behalf of the Company by an executive officer.

          14.  Cancellation  of  Warrant.  Upon  surrender  of this  Warrant for
               transfer or exchange or upon the  exercise  hereof,  this Warrant
               shall be  canceled by the  Company,  shall not be reissued by the
               Company,  and,  except  as  provided  in  Section  6 in case of a
               transfer,  no  Warrant  shall be issued in lieu  hereof.  Any new
               Warrant certificate shall be issued promptly but no later than 14
               days after  receipt  of the old  Warrant  certificate,  provided,
               however,  that the  obligation  of the  Company to  transfer  the
               Warrant or issue the shares of Stock  upon the  exercise  of this
               Warrant shall be subject to compliance with Section 10.

          15.  Complete Agreement: Modifications. This Warrant and any documents
               referred  to  herein  or  executed   contemporaneously   herewith
               constitute  the  parties'  entire  agreement  with respect to the
               subject    matter   hereof   and   supersede   all    agreements,
               representations,    warranties,    statements,    promises    and
               understandings,  whether  oral or  written,  with  respect to the
               subject matter hereof.  This Warrant may not be amended,  altered
               or modified except by a writing signed by the parties.

          16.  Cooperation.  Each party  hereto  agrees to  execute  any and all
               further  documents and writings and perform such other reasonable
               actions  which  may  be  or  become  necessary  or  expedient  to
               effectuate and carry out this Warrant.

          17.  Notices.  All notices  under this Warrant shall be in writing and
               shall be delivered by personal  service or telegram,  telecopy or
               certified  mail,  postage  prepaid,  to  such  address  as may be
               designated  from time to time by the  relevant  party,  and which
               will  initially  be as  set  forth  below.  Any  notice  sent  by
               certified  mail will be deemed to have been given  three (3) days
               after the date on which it is mailed.  All other  notices will be
               deemed  given  when  received.  No  objection  may be made to the
               manner of delivery of any notice actually  received in writing by
               an authorized agent of a party.  Notices will be addressed as set
               forth on the last page hereof or to such other  addresses  as the
               party to whom the same is directed will have specified.

          18.  Successor and Assigns. Except as provided herein to the contrary,
               this  Warrant  shall be binding  upon and inure to the benefit of
               the parties, their respective successors and permitted assigns.

          19.  Governing  Law:  Jurisdiction.  This Warrant shall be governed by
               and construed in  accordance  with the internal laws of the State
               of  Delaware  and  without   giving   effect  to  choice  of  law
               provisions.  No  amendment  or  waiver of any  provision  of this
               Warrant, nor a consent to any departure by the Company therefrom,
               shall  in any  event be  effective  unless  the same  shall be in
               writing and signed by the  Company and the Holder,  and then such
               waiver  or  consent  shall  be  effective  only  in the  specific
               instance  and for the  specific  purpose  for  which  given.  The
               captions of this Warrant have been inserted for convenience  only
               and shall have no substantive effect.

          20.  Construction.  No term  or  provision  of the  Warrant  shall  be
               construed so as to require the  commission of any act contrary to
               law, and wherever there is any conflict  between any provision of
               this Warrant and any present or future statute,  law,  ordinance,
               or  regulation  contrary to which the parties have no legal right
               to  contract,  the latter  shall  prevail,  but in such event the
               provision  of this  Warrant so affected  shall be  curtailed  and
               limited  only to the  extent  necessary  to bring it  within  the
               requirements of the law.

          21.  Waivers Strictly  Construed.  With regard to any power, remedy or
               right  provided  herein  or  otherwise  available  to  any  party
               hereunder  (i) no waiver or  extension of time shall be effective
               unless  expressly  contained  in  writing  signed by the  waiving
               party;  and (ii) no alteration,  modification or impairment shall
               be implied by reason of any previous  waiver,  extension of time,
               delay or omission in exercise, or other indulgence.

          22.  Severability.  If one or more of the  provisions  of this Warrant
               shall be held to be  invalid,  illegal  or  unenforceable  in any
               respect,   the  validity,   legality  or  enforceability  of  the
               remainder of this Warrant shall not be affected.


          23.  Headings.  The headings in this  Warrant are  inserted  only as a
               matter of convenience,  and in no way define, limit, or extend or
               interpret  the  scope  of  this  Warrant  or  of  any  particular
               provision.

          24.  Counterparts.  This  Warrant  may be  executed  in  two  or  more
               counterparts,  each of which shall be deemed an original, but all
               of which together shall constitute one or the same instrument.

          25.  Attorney's  Fees.  Should any litigation be commenced  (including
               any proceedings in a bankruptcy court) between the parties hereto
               or their representatives concerning any provision of this Warrant
               or the rights and duties of any person or entity  hereunder,  the
               party  or  parties   prevailing  in  such  proceedings  shall  be
               entitled,  in addition to such other relief as may be granted, to
               the  attorney's  fees and court costs  incurred by reason of such
               litigation.

          26.  No Brokers etc. Fees. Each party hereto represents that it is not
               and will not be obligated  for any  finder's or broker's  fees or
               commissions  in  connection  with this  Warrant or any  agreement
               referred to herein or contemplated  hereby. The Company agrees to
               indemnify and hold harmless the Warrantholder  from any liability
               for any commission or compensation in the nature of a finder's or
               broker's  fee (and the costs and  expenses of  defending  against
               such  liability or asserted  liability)  for which the Company or
               any of its officers,  employees or  representatives is alleged to
               be responsible.

          27.  Other.  These  Warrants  were  granted to the  Warrantholder  for
               services performed on behalf of the Company.





WITNESS the signature of a duly authorized officer.

Dated:  ____________________, 2003

Hemispherx Biopharma, Inc.


By:___________________________________________________________

   -----------------------------------------
  Title

ADDRESS OF COMPANY:

Hemispherx Biopharma, Inc.
One Penn Center
1617 JFK Boulevard
Philadelphia, PA  19103

Telephone         (215) 988-0080
Fax               (215) 988-1739

ADDRESS OF WARRANTHOLDER:


- ------------------------------------


- ------------------------------------





                           HEMISPHERx BIOPHARMA, INC.
                                  PURCHASE FORM
                     To Be Executed Upon Exercise of Warrant
                                  No. 03-XX-XX

The undersigned  Warrantholder  hereby exercises the right to purchase shares of
Stock,  evidenced by the within  Warrant,  according to the terms and conditions
thereof,  and herewith makes payment of the purchase price in full for _________
shares at the exercise price of $______ per share for a total of $_____________.
The undersigned requests that the certificate(s) for such shares shall be issued
in the name and delivered to the address set forth below:

                                    ------------------------------

If said  number of  shares  shall not be all the  shares  purchasable  under the
within  Warrant,  the  Warrantholder  hereby requests that a new Warrant for the
unexercised  portion ( _______ shares) shall be registered in the name delivered
to the address set forth below.


Dated: ________________

                                    NAME OF WARRANTHOLDER


                                    By:  ___________________________




                                    Address:  _________________________

                                    ___________________________________

                                    Employee Identification Number, Social
                                    Security Number or other identifying
                                    number: _________________________