Exhibit 32.1


                           SECTION 1350 CERTIFICATION


         In connection with the Quarterly Report of Orthofix International N.V.
("Orthofix") on Form 10-Q for the period ended March 31, 2005 (the "Quarterly
Report"), as filed with the Securities and Exchange Commission on the date
hereof, I, Charles W. Federico, Chief Executive Officer, President and Director
of Orthofix, certify, pursuant to 18 U.S.C. Section 1350, that to the best of my
knowledge:

         1. The Quarterly Report fully complies with the requirements of Section
13(a) or 15(d) of the Securities Exchange Act of 1934; and

         2. The information contained in the Quarterly Report fairly presents,
in all material respects, the financial condition and results of operations of
Orthofix.



Dated:  May 4, 2005                         /s/ Charles W. Federico
                                            -----------------------------------
                                            Name:  Charles W. Federico
                                            Title: Chief Executive Officer,
                                                   President and Director