SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K/A |X| ANNUAL REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE ACT 1934 FOR THE FISCAL YEAR ENDED SEPTEMBER 30, 1995 or |_| TRANSITION REPORT PURSUANT TO SECTION 13 OR 15 (d) OF THE SECURITIES EXCHANGE OF 1934 FOR THE TRANSITION PERIOD FROM ______ to _______ Commission File No. 0-18728 INTERNEURON PHARMACEUTICALS, INC. --------------------------------- (Exact name of registrant as specified in its charter) DELAWARE 043047911 - - -------- --------- (State or other jurisdiction of (I.R.S. Employer Identification incorporation or organization) Number) ONE LEDGEMONT CENTER, 99 HAYDEN AVENUE, LEXINGTON, MA 02173 - - ----------------------------------------------------- ----- (Address of principal executive offices) (Zip Code) Registrant's telephone number, including area code: (617) 861-8444 Securities registered pursuant to Section 12(b) of the Act: None Securities registered pursuant to Section 12(g) of the Act: Common Stock, $.001 par value Redeemable Class B Warrants Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding twelve (12) months (or for such shorter period that the registrant was required to file such report(s)), and (2) has been subject to the filing requirements for the past ninety (90) days. YES X NO Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein, and will not be contained, to the best of registrant's knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K or any amendment to this Form 10-K [X]. The aggregate market value of the voting stock (excluding preferred stock convertible into and having voting rights on certain matters equivalent to 622,221 shares of common stock) held by non-affiliates of the registrant was approximately $285 million, based on the last sales price of the Common Stock as of December 18, 1995. As of December 18, 1995, 33,683,690 shares of Common Stock, $.001 par value, of the registrant were issued and outstanding. DOCUMENTS INCORPORATED BY REFERENCE See Part III hereof with respect to incorporation by reference from the registrant's definitive proxy statement to be filed pursuant to Regulation 14A under the Securities Exchange Act of 1934 and the Exhibit Index hereto. C:\BTPM_NY_\46\0044680.01 1 PART IV 14. EXHIBITS, FINANCIAL STATEMENTS SCHEDULES AND REPORTS ON FORM 8-K (a) 1. Financial Statements An index to Consolidated Financial Statements appears on page F-1 2. Schedules All financial statement schedules are omitted because they are not applicable, not required under the instructions or all the information required is set forth in the financial statements or notes thereto. 3. Exhibits 3.4 - Restated Certificate of Incorporation of Registrant (17) 3.5 - By-Laws of Registrant (1) 4.2 - Form of Warrant Agreement (1) 4.4 - Certificate of Designation establishing Series C Preferred Stock (17) 4.5 - Warrant issued to Elan Corporation, plc (19) 4.6 - Form of Registrant Warrant issued in subsidiary private placement (25) 4.7 - Form of Registrant Warrant to be issued to Paramount Capital, Inc., D.H. Blair & Co., Inc. or designees (25) 10.5 (a) - Consultant and Non-competition Agreement between the Registrant, Richard Wurtman, M.D. 10.5 (b) - Consultant and Non-competition Agreement between InterNutria, Inc. and Judith Wurtman, Ph.D. 10.6 - Assignment of Invention and Agreement between Richard Wurtman, M.D., Judith Wurtman and the Registrant (1) 10.7 - Management Agreement between the Registrant and Lindsay Rosenwald, M.D. (1) 10.9(a) - Restated and Amended 1989 Stock Option Plan (7) 10.10 - Form of Indemnification Agreement (1) 10.11 - Restated Amendment to MIT Option Agreement (1) 10.12(a) - Patent and Know-How License Agreement between the Registrant and Les Laboratoires Servier ("Servier") dated February 7, 1990 ("License Agreement") (1) 10.12(b) - Revised Appendix A to License Agreement (1) 10.12(c) - Amendment Agreement between Registrant and Servier, Orsem and Oril, Produits Chimiques dated November 19,1992(3)(12) 10.12(d) - Amendment Agreement dated April 28, 1993 between Registrant and Servier (16) C:\BTPM_NY_\46\0044680.01 2 10.12 (e) - Consent and Amendment Agreement among Servier, American Home Products Corp. and Registrant. 10.13 - Trademark License Agreement between the Registrant and Orsem dated February 7, 1990 (1) 10.14 - Supply Agreement between the Registrant and Oril Products Chimiques dated February 7, 1990 (1)(3) 10.15(a) - Form of Indemnification Agreement between the Registrant and Alexander M. Haig, Jr. (1) 10.16 - Assignment of Invention by Richard Wurtman, M.D. (1) 10.18 - Option Agreement between the Registrant and Alexander M. Haig, Jr. (1) 10.19 - Option Agreement between the Registrant and Fountainhead Holdings (Bermuda) Ltd. (1) 10.22(a) - License Agreement dated January 15, 1993, as amended, between the Registrant and Group Ferrer (3)(16) 10.25 - License Agreement between the Registrant and the Massachusetts Institute of Technology (4) 10.27 - License Agreement dated July 1, 1991 between Whitby Research, Inc. and the Registrant (6) 10.28 - Letter Agreement between the Registrant and Bobby W. Sandage, Jr., Ph.D. (7) 10.29 - Amended Lease dated December 12, 1991 for Registrant's offices in Lexington, Massachusetts (7) 10.29(a) - First Amendment to Lease dated as of October 14, 1994 between Registrant and Ledgemont Realty Trust (25) 10.30 - License Agreement dated January 1, 1992 between the Trustees of Princeton University and the Registrant(3)(8) 10.31 - Research Agreement dated as of July 1, 1991 between the Registrant and the Trustees of Princeton University (3 (8) 10.32 - Consulting Agreement dated as of July 1, 1991 between the Registrant and Daniel Kahne, Ph.D. (3)(8) 10.33 - License Agreement dated January 28, 1992 between Ohio University, The Castle Group, Inc. and Scimark Corporation (assigned to Progenitor, Inc.) (3)(8) 10.34 - Sponsored Research Agreement between Scimark Corporation (assigned to Progenitor, Inc.) and Ohio University (3)(8) 10.34(a) - Letter Amendment between Progenitor, Inc. and Ohio University (18) 10.35 - Technology License Contract dated December 18, 1991 between the Registrant and the Mayo Foundation for Medical Education and Research (3) (8) 10.36 - Exclusive License Agreement dated February 24, 1992 between the Registrant and Purdue Research Foundation (9) 10.37 - License Agreement dated as of February 15, 1992 between the Registrant and Massachusetts Institute of Technology (9) 10.38 - Employment Agreement between Progenitor, Inc. and Glenn Cooper, M.D. dated September 3, 1992 (13) C:\BTPM_NY_\46\0044680.01 3 10.39 - Employment Agreement between Transcell Technologies, Inc. and Elizabeth Tallet dated November 11, 1992 and Guarantee by Registrant (13) 10.40 - Patent and Know-How Sublicense and Supply Agreement between Registrant and American Cyanamid Company dated November 19, 1992 (3)(12) 10.41 - Equity Investment Agreement between Registrant and American Cyanamid Company dated November 19, 1992 (12) 10.42 - Trademark License Agreement between Registrant and American Cyanamid Company dated November 19, 1992 (12) 10.43 - Consent Agreement between Registrant and Servier dated November 19,1992 (12) 10.44 - Patent and Know-How License Agreement between Registrant and Veryfine Products, Inc. dated October 29, 1992 (3) (14) 10.44(a) - Termination Letter to Registrant from Veryfine Products, Inc., dated October 30, 1995. 10.45 - Agreement between Registrant and Parexel International Corporation dated October 22, 1992 (as of July 21, 1992) (3) (14) 10.46 - License Agreement dated February 9, 1993 between the Registrant and Massachusetts Institute of Technology (3) (15) 10.47 - Sublease between Enichem America and Transcell Technologies, Inc. including guarantee by the Registrant (15) 10.48 - Employment Agreement dated May 21, 1993 between the Registrant and Glenn L. Cooper, M.D., as amended (17) 10.49 - License Agreement between Registrant and Elan Corporation, plc dated September 9, 1993 (3)(18) 10.50 - License Agreement between Transcell Technologies, Inc. and Princeton University dated October 14, 1993 (3)(18) 10.51 - Letter Agreement between the Registrant and Mark S. Butler (18) 10.52 - License Agreement dated February 18, 1994 between Registrant and Rhone-Poulenc Rorer, S.A. (20) 10.54 - Form of Purchase Agreement dated as of February 24, 1994 (20) 10.54(a) - Form of Amendment to Purchase Agreement (20) 10.55 - Patent License Agreement between Registrant and Massachusetts Institute of Technology dated March 1, 1994 (20) 10.56 - License Agreement between Progenitor, Inc. and Albert Einstein College of Medicine of Yeshiva University dated as of February 1,1994 (20) 10.57 - Employment Letter dated February 28, 1994 between the Registrant and Thomas F. Farb (21) 10.58 - Master Equipment Lease including Schedules and Exhibits between Phoenix Leasing and Registrant (agreements for Transcell and Progenitor are substantially identical), with form of continuing guarantee for each of Transcell and Progenitor (22) 10.59 - Exhibit D to Agreement between Registrant and Parexel International Corporation dated as of March 15, 1994. (3)(22) C:\BTPM_NY_\46\0044680.01 4 10.60(a) - Acquisition Agreement dated as of May 13, 1994 among the Registrant, Intercardia, Inc., Cardiovascular Pharmacology Engineering Consultants, Inc. (CPEC), Myocor, Inc. and the sellers named therein (23) 10.60(b) - Amendment dated June 15, 1994 to the Acquisition Agreement (23) 10.60(c) - Form of Consulting Agreement between Intercardia, Inc., CPEC and Myocor, Inc.(23) 10.61 - License Agreement dated December 6, 1991 between Bristol- Myers Squibb and CPEC, as amended (3)(23) 10.61(a) - Letter Agreement dated November 18, 1994 between CPEC and Bristol-Myers Squibb (25) 10.62 - Lease Agreement between Thomas R. Eggers and Progenitor, Inc. dated as of November 1994 with Registrant guaranty (25) 10.63 - Form of Stock Purchase Agreement dated December 15, 1994 (25) 10.64 - Form of Investor Rights Agreement among Progenitor, Transcell, Registrant and each investor in the subsidiary private placement (25) 10.64(a) - Form of Investor Rights Agreement among Intercardia, the Registrant and each investor in the Intercardia private placement (25) 10.65 - 1994 Long-Term Incentive Plan (25) 10.66 - Guarantee by Lindsay A. Rosenwald, M.D. to Registrant (25) 10.67 - Employment Agreement between Intercardia and Clayton I. Duncan with Registrant guarantee (25) 10.67(a) - Amendment to Employment Agreement between Intercardia, Inc. and Clayton I. Duncan (27) 10.68 - Interneuron Pharmaceuticals, Inc. 1995 Employee Stock Purchase Plan, as amended (27) 10.69 - Office Lease, dated April 24, 1995 between Intercardia, Inc. and Highwoods/Forsyth Limited Partnership, with Registrant Guaranty (27) 10.70 - Letter Agreement, dated March 31, 1995 between Progenitor, Inc. and Chiron Corporation (3) (28) 10.70(a) - License and Collaboration Agreement by and between Progenitor, Inc., and Chrion Corporation dated March 31, 1995 (3) (30) 10.71 - Securities Purchase Agreement dated June 2, 1995 between the Registrant and Reliance Insurance Company, including Warrant and exhibits (29) 10.72 - Sponsored Research and License Agreement dated as of May 1, 1995 between Progenitor and Novo Nordisk (3) (30) 10.73 - Form of Stock Purchase Agreement dated as of June 28, 1995 (31) 10.74 - Securities Purchase Agreement dated as of August 16, 1995 between the Registrant and BT Holdings (New York), Inc., including Warrant issued to Momint (nominee of BT Holdings) (32) 10.75 - Stock Purchase Agreement dated as August 23, 1995 between the Registrant and Paresco, Inc. (32) 10.76 - Stock Purchase Agreement dated as of September 15, 1995 between the Registrant and Silverton International Fund Limited (32) C:\BTPM_NY_\46\0044680.01 5 10.77 - Subscription Agreement dated September 21, 1995, as of August 31, 1995, including Registration Rights Agreement between Registrant and GFL Advantage Fund Limited. (32) 10.78 - Contract Manufacturing Agreement dated November 20,1995 between Registrant and Boehringer Ingelheim Pharmaceuticals, Inc. (3) 10.79 - Development and Marketing Collaboration and License Agreement between Astra Merck, Inc., Intercardia, Inc. and CPEC, Inc., dated December 4, 1995. (33) 10.80 - Intercompany Services Agreement between Registrant and Intercardia, Inc. (33) 10.81 - Asset Purchase Agreement dated November 14, 1995 among Registrant, InterNutria, Inc., and Walden Laboratories, Inc. 19 - Letter to Stockholders dated May 18, 1994 (24). 20 - News Release dated August 10, 1994 including Rule 135(c) notice (21) 21 - Subsidiaries of the Registrant 23 - Consent of Coopers & Lybrand L.L.P. 27 - Financial Data Schedule - - --------------------------- (1) Incorporated by reference to the Registrant's registration statement on Form S-1 (File No. 33- 32408) declared effective on March 8, 1990. (3) Confidential Treatment requested for a portion of this Exhibit. (4) Incorporated by reference to the Registrant's Annual Report on Form 10-K for the year ended September 30, 1990. (6) Incorporated by reference to the Registrant's Quarterly report on Form 10-Q for the nine months ended June 30, 1991. (7) Incorporated by reference to Post-Effective Amendment No. 2 to the Registrant's registration statement on Form S-1 (File No. 33-32408) filed December 18, 1991. (8) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the three months ended December 31, 1991. (9) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the three months ended March 31, 1992. (10) Incorporated by reference to Post-Effective Amendment No. 3 to the Registrant's registration statement on Form S-1 (File No. 33-32408) filed July 12, 1992. (11) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the three months ended June 30, 1992. (12) Incorporated by reference to the Registrant's Form 8-K dated November 30, 1992. (13) Incorporated by reference to Post-Effective Amendment No. 5 to the Registrant's Registration Statement on Form S-1 (File No. 33-32408) filed on December 21, 1992. (14) Incorporated by reference to the Registrant's Annual Report on Form 10-K for the fiscal year ended September 30, 1992. C:\BTPM_NY_\46\0044680.01 6 (15) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the three months ended December 31, 1992 (16) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the six months ended March 31, 1993 (17) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the nine months ended June 30, 1993 (18) Incorporated by reference to the Registrant's Annual Report on Form 10-K for the fiscal year ended September 30, 1993 (19) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the three months ended December 31, 1993. (20) Incorporated by reference to the Registrant's Registration Statement on Form S-3 or Amendment No. 1 (File no. 33-75826) (21) Incorporated by reference to the Registrant's Form 8-K dated March 31, 1994 (22) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the six months ended March 31, 1994 (23) Incorporated by reference to the Registrant's Form 8-K dated June 20, 1994 (24) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the nine months ended June 30, 1994 (25) Incorporated by reference to the Registrant's Annual Report on Form 10-K for the fiscal year ended September 30, 1994 (26) Incorporated by reference to Registrant's Quarterly Report on Form 10-Q for the three months ended December 31, 1994 (27) Incorporated by reference to the Registrant's Quarterly Report on From 10-Q for the six months ended March 31, 1995 (28) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q/A for the six months ended March 31, 1995 (29) Incorporated by reference to the Registrant's Quarterly Report on Form 8-K dated June 2, 1995 (30) Incorporated by reference to the Registrant's Quarterly Report on Form 8-K dated May 16, 1995; Exhibit 10.70 (a) supersedes Exhibit 10.70. (31) Incorporated by reference to Registrant's Quarterly Report on Form 10-Q for the nine months ended June 30, 1995. (32) Incorporated by referring to Registrant's Report on Form 8-K dated August 16, 1995. (33) Incorporated by reference to Registration Statement filed on Form S-1 (No. 33-80219) by Intercardia, Inc. on December 8, 1995. (b) Reports on Form 8-K The Company filed reports on Form 8-K dated August 16, 1995 and September 28, 1995. C:\BTPM_NY_\46\0044680.01 7 SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. INTERNEURON PHARMACEUTICALS, INC. /s/ Glenn L. Cooper ---------------------------------- Glenn L. Cooper, M.D. President and Chief Executive Officer Dated: March 13, 1996 C:\BTPM_NY_\46\0044680.01 8 EXHIBIT INDEX 3.4 - Restated Certificate of Incorporation of Registrant (17) 3.5 - By-Laws of Registrant (1) 4.2 - Form of Warrant Agreement (1) 4.4 - Certificate of Designation establishing Series C Preferred Stock (17) 4.5 - Warrant issued to Elan Corporation, plc (19) 4.6 - Form of Registrant Warrant issued in subsidiary private placement (25) 4.7 - Form of Registrant Warrant to be issued to Paramount Capital, Inc., D.H. Blair & Co., Inc. or designees (25) 10.5 (a) - Consultant and Non-competition Agreement between the Registrant, Richard Wurtman, M.D. 10.5 (b) - Consultant and Non-competition Agreement between InterNutria, Inc. and Judith Wurtman, Ph.D. 10.6 - Assignment of Invention and Agreement between Richard Wurtman, M.D., Judith Wurtman and the Registrant (1) 10.7 - Management Agreement between the Registrant and Lindsay Rosenwald, M.D. (1) 10.9(a) - Restated and Amended 1989 Stock Option Plan (7) 10.10 - Form of Indemnification Agreement (1) 10.11 - Restated Amendment to MIT Option Agreement (1) 10.12(a) - Patent and Know-How License Agreement between the Registrant and Les Laboratoires Servier ("Servier") dated February 7, 1990 ("License Agreement") (1) 10.12(b) - Revised Appendix A to License Agreement (1) 10.12(c) - Amendment Agreement between Registrant and Servier, Orsem and Oril, Produits Chimiques dated November 19,1992(3)(12) 10.12(d) - Amendment Agreement dated April 28, 1993 between Registrant and Servier (16) 10.12 (e) - Consent and Amendment Agreement among Servier, American Home - Products Corp. and Registrant. 10.13 - Trademark License Agreement between the Registrant and Orsem dated February 7, 1990 (1) 10.14 - Supply Agreement between the Registrant and Oril Products Chimiques dated February 7, 1990 (1)(3) 10.15(a) - Form of Indemnification Agreement between the Registrant and Alexander M. Haig, Jr. (1) 10.16 - Assignment of Invention by Richard Wurtman, M.D. (1) 10.18 - Option Agreement between the Registrant and Alexander M. Haig, Jr. (1) 10.19 - Option Agreement between the Registrant and Fountainhead Holdings (Bermuda) Ltd. (1) 10.22(a) - License Agreement dated January 15, 1993, as amended, between the Registrant and Group Ferrer (3)(16) C:\BTPM_NY_\46\0044680.01 1 10.25 - License Agreement between the Registrant and the Massachusetts Institute of Technology (4) 10.27 - License Agreement dated July 1, 1991 between Whitby Research, Inc. and the Registrant (6) 10.28 - Letter Agreement between the Registrant and Bobby W. Sandage, Jr., Ph.D. (7) 10.29 - Amended Lease dated December 12, 1991 for Registrant's offices in Lexington, Massachusetts (7) 10.29(a) - First Amendment to Lease dated as of October 14, 1994 between Registrant and Ledgemont Realty Trust (25) 10.30 - License Agreement dated January 1, 1992 between the Trustees of Princeton University and the Registrant (3)(8) 10.31 - Research Agreement dated as of July 1, 1991 between the Registrant and the Trustees of Princeton University (3)(8) 10.32 - Consulting Agreement dated as of July 1, 1991 between the Registrant and Daniel Kahne, Ph.D. (3)(8) 10.33 - License Agreement dated January 28, 1992 between Ohio University, The Castle Group, Inc. and Scimark Corporation (assigned to Progenitor, Inc.) (3)(8) 10.34 - Sponsored Research Agreement between Scimark Corporation (assigned to Progenitor, Inc.) and Ohio University (3)(8) 10.34(a) - Letter Amendment between Progenitor, Inc. and Ohio University (18) 10.35 - Technology License Contract dated December 18, 1991 between the Registrant and the Mayo Foundation for Medical Education and Research (3) (8) 10.36 - Exclusive License Agreement dated February 24, 1992 between the Registrant and Purdue Research Foundation (9) 10.37 - License Agreement dated as of February 15, 1992 between the Registrant and Massachusetts Institute of Technology (9) 10.38 - Employment Agreement between Progenitor, Inc. and Glenn Cooper, M.D. dated September 3, 1992 (13) 10.39 - Employment Agreement between Transcell Technologies, Inc. and Elizabeth Tallet dated November 11, 1992 and Guarantee by Registrant (13) 10.40 - Patent and Know-How Sublicense and Supply Agreement between Registrant and American Cyanamid Company dated November 19, 1992 (3)(12) 10.41 - Equity Investment Agreement between Registrant and American Cyanamid Company dated November 19, 1992 (12) 10.42 - Trademark License Agreement between Registrant and American Cyanamid Company dated November 19, 1992 (12) 10.43 - Consent Agreement between Registrant and Servier dated November 19,1992 (12) 10.44 - Patent and Know-How License Agreement between Registrant \ and Veryfine Products, Inc. dated October 29, 1992 (3) (14) 10.44(a) - Termination Letter to Registrant from Veryfine Products, Inc., dated October 30, 1995. 10.45 - Agreement between Registrant and Parexel International Corporation dated October 22, 1992 (as of July 21, 1992) (3) (14) C:\BTPM_NY_\46\0044680.01 2 10.46 - License Agreement dated February 9, 1993 between the Registrant and Massachusetts Institute of Technology (3)(15) 10.47 - Sublease between Enichem America and Transcell Technologies, Inc. including guarantee by the Registrant (15) 10.48 - Employment Agreement dated May 21, 1993 between the Registrant and Glenn L. Cooper, M.D., as amended (17) 10.49 - License Agreement between Registrant and Elan Corporation, plc dated September 9, 1993 (3)(18) 10.50 - License Agreement between Transcell Technologies, Inc. and Princeton University dated October 14, 1993 (3)(18) 10.51 - Letter Agreement between the Registrant and Mark S. Butler (18) 10.52 - License Agreement dated February 18, 1994 between Registrant and Rhone-Poulenc Rorer, S.A. (20) 10.54 - Form of Purchase Agreement dated as of February 24, 1994 (20) 10.54(a) - Form of Amendment to Purchase Agreement (20) 10.55 - Patent License Agreement between Registrant and Massachusetts Institute of Technology dated March 1, 1994 (20) 10.56 - License Agreement between Progenitor, Inc. and Albert Einstein College of Medicine of Yeshiva University dated as of February 1,1994 (20) 10.57 - Employment Letter dated February 28, 1994 between the Registrant and Thomas F. Farb (21) 10.58 - Master Equipment Lease including Schedules and Exhibits between Phoenix Leasing and Registrant (agreements for Transcell and Progenitor are substantially identical), with form of continuing guarantee for each of Transcell and Progenitor (22) 10.59 - Exhibit D to Agreement between Registrant and Parexel International Corporation dated as of March 15, 1994. (3)(22) 10.60(a) - Acquisition Agreement dated as of May 13, 1994 among the Registrant, Intercardia, Inc., Cardiovascular Pharmacology Engineering Consultants, Inc. (CPEC), Myocor, Inc. and the sellers named therein (23) 10.60(b) - Amendment dated June 15, 1994 to the Acquisition Agreement (23) 10.60(c) - Form of Consulting Agreement between Intercardia, Inc., CPEC and Myocor, Inc.(23) 10.61 - License Agreement dated December 6, 1991 between Bristol- Myers Squibb and CPEC, as amended (3)(23) 10.61(a) - Letter Agreement dated November 18, 1994 between CPEC and Bristol-Myers Squibb (25) 10.62 - Lease Agreement between Thomas R. Eggers and Progenitor, Inc. dated as of November 1994 with Registrant guaranty (25) 10.63 - Form of Stock Purchase Agreement dated December 15, 1994 (25) 10.64 - Form of Investor Rights Agreement among Progenitor, Transcell, Registrant and each investor in the subsidiary private placement (25) 10.64(a) - Form of Investor Rights Agreement among Intercardia, the Registrant and each investor in the Intercardia private placement (25) C:\BTPM_NY_\46\0044680.01 3 10.65 - 1994 Long-Term Incentive Plan (25) 10.66 - Guarantee by Lindsay A. Rosenwald, M.D. to Registrant (25) 10.67 - Employment Agreement between Intercardia and Clayton I. Duncan with Registrant guarantee (25) 10.67(a) - Amendment to Employment Agreement between Intercardia, Inc. and Clayton I. Duncan (27) 10.68 - Interneuron Pharmaceuticals, Inc. 1995 Employee Stock Purchase Plan, as amended (27) 10.69 - Office Lease, dated April 24, 1995 between Intercardia, Inc. and Highwoods/Forsyth Limited Partnership, with Registrant Guaranty (27) 10.70 - Letter Agreement, dated March 31, 1995 between Progenitor, Inc. and Chiron Corporation (3) (28) 10.70 (a) - License and Collaboration Agreement by and between Progenitor, Inc., and Chrion Corporation dated March 31, 1995 (3) (30) 10.71 - Securities Purchase Agreement dated June 2, 1995 between the Registrant and Reliance Insurance Company, including Warrant and exhibits (29) 10.72 - Sponsored Research and License Agreement dated as of May 1, 1995 between Progenitor and Novo Nordisk (3) (30) 10.73 - Form of Stock Purchase Agreement dated as of June 28, 1995 (31) 10.74 - Securities Purchase Agreement dated as of August 16, 1995 between the Registrant and BT Holdings (New York), Inc., including Warrant issued to Momint (nominee of BT Holdings) (32) 10.75 - Stock Purchase Agreement dated as August 23, 1995 between the Registrant and Paresco, Inc. (32) 10.76 - Stock Purchase Agreement dated as of September 15, 1995 between the Registrant and Silverton International Fund Limited (32) 10.77 - Subscription Agreement dated September 21, 1995, as of August 31, 1995, including Registration Rights Agreement between Registrant and GFL Advantage Fund Limited. (32) 10.78 - Contract Manufacturing Agreement dated November 20,1995 between Registrant and Boehringer Ingelheim Pharmaceuticals, Inc. (3) 10.79 - Development and Marketing Collaboration and License Agreement between Astra Merck, Inc., Intercardia, Inc. and CPEC, Inc., dated December 4, 1995. (33) 10.80 - Intercompany Services Agreement between Registrant and Intercardia, Inc. (33) 10.81 - Asset Purchase Agreement dated November 14, 1995 among Registrant, InterNutria, Inc., and Walden Laboratories, Inc. 19 - Letter to Stockholders dated May 18, 1994 (24). 20 - News Release dated August 10, 1994 including Rule 135(c) notice (21) 21 - Subsidiaries of the Registrant 23 - Consent of Coopers & Lybrand L.L.P. 27 - Financial Data Schedule C:\BTPM_NY_\46\0044680.01 4 - - --------------------------- (1) Incorporated by reference to the Registrant's registration statement on Form S-1 (File No. 33- 32408) declared effective on March 8, 1990. (3) Confidential Treatment requested for a portion of this Exhibit. (4) Incorporated by reference to the Registrant's Annual Report on Form 10-K for the year ended September 30, 1990. (6) Incorporated by reference to the Registrant's Quarterly report on Form 10-Q for the nine months ended June 30, 1991. (7) Incorporated by reference to Post-Effective Amendment No. 2 to the Registrant's registration statement on Form S-1 (File No. 33-32408) filed December 18, 1991. (8) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the three months ended December 31, 1991. (9) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the three months ended March 31, 1992. (10) Incorporated by reference to Post-Effective Amendment No. 3 to the Registrant's registration statement on Form S-1 (File No. 33-32408) filed July 12, 1992. (11) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the three months ended June 30, 1992. (12) Incorporated by reference to the Registrant's Form 8-K dated November 30, 1992. (13) Incorporated by reference to Post-Effective Amendment No. 5 to the Registrant's Registration Statement on Form S-1 (File No. 33-32408) filed on December 21, 1992. (14) Incorporated by reference to the Registrant's Annual Report on Form 10-K for the fiscal year ended September 30, 1992. (15) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the three months ended December 31, 1992 (16) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the six months ended March 31, 1993 (17) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the nine months ended June 30, 1993 (18) Incorporated by reference to the Registrant's Annual Report on Form 10-K for the fiscal year ended September 30, 1993 (19) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the three months ended December 31, 1993. (20) Incorporated by reference to the Registrant's Registration Statement on Form S-3 or Amendment No. 1 (File no. 33-75826) (21) Incorporated by reference to the Registrant's Form 8-K dated March 31, 1994 (22) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the six months ended March 31, 1994 (23) Incorporated by reference to the Registrant's Form 8-K dated June 20, 1994 (24) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the nine months ended June 30, 1994 (25) Incorporated by reference to the Registrant's Annual Report on Form 10-K for the fiscal year ended September 30, 1994 C:\BTPM_NY_\46\0044680.01 5 (26) Incorporated by reference to Registrant's Quarterly Report on Form 10-Q for the three months ended December 31, 1994 (27) Incorporated by reference to the Registrant's Quarterly Report on From 10-Q for the six months ended March 31, 1995 (28) Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q/A for the six months ended March 31, 1995 (29) Incorporated by reference to the Registrant's Quarterly Report on Form 8-K dated June 2, 1995 (30) Incorporated by reference to the Registrant's Quarterly Report on Form 8-K dated May 16, 1995; Exhibit 10.70 (a) supersedes Exhibit 10.70. (31) Incorporated by reference to Registrant's Quarterly Report on Form 10-Q for the nine months ended June 30, 1995. (32) Incorporated by referring to Registrant's Report on Form 8-K dated August 16, 1995. (33) Incorporated by reference to Registration Statement filed on Form S-1 (No. 33-80219) by Intercardia, Inc. on December 8, 1995. C:\BTPM_NY_\46\0044680.01 6