Exhibit 16.1 TOURVILLE, SIMPSON & CASKEY, L.L.P. CERTIFIED PUBLIC ACCOUNTANTS POST OFFICE BOX 1769 COLUMBIA, SOUTH CAROLINA 29202 TELEPHONE (803) 252-3000 FAX (803) 252-2226 WILLIAM E. TOURVILLE, CPA MEMBER AICPA SEC AND HARRIET S. SIMPSON, CPA, CISA, CDP PRIVATE COMPANIES R. JASON CASKEY, CPA PRACTICE SECTIONS TIMOTHY R. ALFORD, CPA W. CLAYTON HESLOP, CPA TIMOTHY S. VOGEL, CPA January 2, 2003 Securities and Exchange Commission 450 Fifth Street, N. W. Washington, D. C. 20549 Re: Regional Bankshares, Inc. Ladies and Gentlemen: As of the date of this letter, we resigned as auditors for Regional Bankshares, Inc. We have read Item 4 of the Form 8-K of Regional Bankshares, Inc dated January 2, 2003 and to be filed with the Securities and Exchange Commission and agree with statements concerning our firm contained therein. Very Truly Yours, s/Tourville, Simpson and Caskey, LLP Tourville, Simpson and Caskey, LLP