Exhibit 16.1 TOURVILLE, SIMPSON & CASKEY, L.L.P. CERTIFIED PUBLIC ACCOUNTANTS POST OFFICE BOX 1769 COLUMBIA, SOUTH CAROLINA 29202 TELEPHONE (803) 252-3000 FAX (803) 252-2226 WILLIAM E. TOURVILLE, CPA MEMBER AICPA SEC AND HARRIET S. SIMPSON, CPA, CISA, CDP PRIVATE COMPANIES R. JASON CASKEY, CPA PRACTICE SECTIONS TIMOTHY R. ALFORD, CPA W. CLAYTON HESLOP, CPA TIMOTHY S. VOGEL, CPA February 4, 2003 Securities and Exchange Commission 450 Fifth Street, N. W. Washington, D. C. 20549 Re: Regional Bankshares, Inc. Ladies and Gentlemen: We have read Item 4 of Amendment No. 1 to the Form 8-K of Regional Bankshares, Inc., dated January 2,2003, to be filed with the Securities and Exchange Commission and agree with statements concerning our firm contained therein. Very Truly Yours, s/Tourville, Simpson and Caskey, LLP Tourville, Simpson and Caskey, LLP