UNITED STATES SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                  SCHEDULE 14A

          Proxy Statement Pursuant to Section 14(a) of the Securities
                              Exchange Act of 1934

Filed by the Registrant [X]

Filed by a Party other than the Registrant [_]

Check the appropriate box:

     [_]  Preliminary Proxy Statement

     [_]  Confidential, For Use of the Commission
          Only (as permitted by Rule 14a-6(e) (2))

     [X]  Definitive Proxy Statement

     [_]  Definitive Additional materials

     [_]  Soliciting Material Pursuant to ss.240.14a-12


                         HUMAN PHEROMONE SCIENCES, INC.
- --------------------------------------------------------------------------------
                (Name of Registrant as Specified in Its Charter)


- --------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if Other Than the Registrant)


Payment of Filing Fee (Check the appropriate box):

     [X]  No fee required.

     [_]  Fee computed on table below per  Exchange  Act Rules  14a-6(i) (1) and
          0-11.


     (1)  Title of each class of securities to which transaction applies:


- --------------------------------------------------------------------------------
     (2)  Aggregate number of securities to which transaction applies:


- --------------------------------------------------------------------------------
     (3) Per unit  price  or other  underlying  value  of  transaction  computed
pursuant to Exchange Act Rule 0-11 (set forth the amount on which the filing fee
is calculated and state how it was determined):


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     (4)  Proposed maximum aggregate value of transaction:


- --------------------------------------------------------------------------------
     (5)  Total fee paid:


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     [_]  Fee paid previously with preliminary materials:

     [_] Check box if any part of the fee is offset as provided by Exchange  Act
Rule 0-11(a) (2) and identify the filing for which the  offsetting  fee was paid
previously.  Identify the previous filing by registration  statement  number, or
the form or schedule and the date of its filing.


     (1)  Amount previously paid:

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     (2)  Form, Schedule or Registration Statement No.:

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     (4)  Date Filed:

- --------------------------------------------------------------------------------


                         HUMAN PHEROMONE SCIENCES, INC.

                    Notice of Annual Meeting of Shareholders
                            to be held June 21, 2006
                      ____________________________________


To the Shareholders of Human Pheromone Sciences, Inc.:


     The  annual  meeting  of  shareholders  (the  "Annual  Meeting")  of  Human
Pheromone Sciences, Inc. (the "Company" or "HPS") will be held at the offices of
Heller Ehrman LLP, 275 Middlefield  Road, Menlo Park,  California 94025, on June
21, 2006, at 10:00 am local time, for the following purposes:


     (1)  To elect four Directors to hold office until the next Annual Meeting;


     (2)  To act upon such  other  business  as may  properly  come  before  the
          meeting.


     These items of business  are more fully  described  in the Proxy  Statement
accompanying this notice.


     Only shareholders of record at the close of business on April 28, 2006, are
entitled to notice of, and to vote at the Annual Meeting and any adjournments or
postponements thereof.


     All  shareholders  are  cordially  invited to attend the meeting in person.
However, to assure your  representation at the meeting,  please mark, sign, date
and return the  enclosed  proxy card as soon as possible in the  postage-prepaid
envelope  enclosed for that purpose.  Any shareholder  attending the meeting may
vote in person even if the shareholder has returned a proxy.



                                       BY ORDER OF THE BOARD OF DIRECTORS



                                               Julian N. Stern, Secretary


San Jose, California
April 24, 2006

================================================================================
WHETHER OR NOT YOU EXPECT TO ATTEND THE ANNUAL  MEETING IN PERSON,  PLEASE  SIGN
AND RETURN THE  ENCLOSED  PROXY AS SOON AS  POSSIBLE  IN THE  ENCLOSED  POSTPAID
ENVELOPE. THANK YOU FOR ACTING PROMPTLY.
================================================================================



                         HUMAN PHEROMONE SCIENCES, INC.
                      84 West Santa Clara Street, Suite 720
                           San Jose, California 95113
                            Telephone: (408) 938-3030
                          _____________________________

                                 PROXY STATEMENT
                          _____________________________


INFORMATION CONCERNING SOLICITATION AND VOTING


     The enclosed  proxy is  solicited on behalf of the Board of Directors  (the
"Board") of Human  Pheromone  Sciences,  Inc.,  a  California  corporation  (the
"Company"). The proxy is solicited for use at the annual meeting of shareholders
(the "Annual Meeting") to be held at 10:00 a.m. local time on June 21, 2006, and
any  adjournments  therof,  at the offices of Heller Ehrman LLP, 275 Middlefield
Road,  Menlo Park,  California  94025.  The approximate date on which this proxy
statement and accompanying  notice and proxy are being mailed to shareholders is
May 10, 2006.


Record Date and Shares Outstanding
- ----------------------------------


     Only shareholders of record at the close of business on April 28, 2006, are
entitled to notice of, and to vote at the Annual Meeting and any adjournments or
postponements  thereof.  At the close of business on that date,  the Company had
outstanding  4,151,954  shares of Common  Stock.  Holders of a  majority  of the
outstanding  shares of common stock of the Company,  either present in person or
by proxy, will constitute a quorum for the transaction of business at the Annual
Meeting.


Revocability of Proxies
- -----------------------


     Any  shareholder  giving  a  proxy  in the  form  accompanying  this  proxy
statement has the power to revoke the proxy prior to its  exercise.  A proxy can
be revoked by an instrument of revocation  delivered prior to the Annual Meeting
to the Secretary of the Company,  by a duly executed  proxy bearing a later date
or time  than the date or time of the  proxy  being  revoked,  or at the  Annual
Meeting  if the  shareholder  is  present  and  elects to vote in  person.  Mere
attendance at the Annual Meeting will not serve to revoke a proxy.


Voting and Solicitation
- -----------------------


     On all matters that come before the Annual Meeting all common  shareholders
are entitled to one vote for each share held.


     In the election of directors, the four persons receiving the highest number
of "FOR"  votes at the  Annual  Meeting  will be  elected.  The  other  proposal
requires the  affirmative  "FOR" vote of a majority of those  shares  present in
person or  represented  by proxy and  entitled  to vote on the  proposal  at the
Annual  Meeting.  If you hold  shares  beneficially  in  street  name and do not
provide  your  broker or  nominee  with  voting  instructions,  your  shares may
constitute  "broker  non-votes."  Generally,  broker non-votes occur on a matter
when a broker is not permitted to vote on that matter without  instructions from
the beneficial owner and instructions are not given. For purposes of determining
the number of shares voting on a particular proposal,  votes cast for or against
a  proposal  and  abstentions  are  counted  as shares  voting,  whereas  broker
non-votes are not counted as shares voting. Accordingly, an abstention will have
the same effect as a vote against the  proposal,  and broker  non-votes can have
the  effect of  preventing  approval  of certain  proposals  where the number of
affirmative  votes,  though a majority of the votes cast,  does not constitute a
majority of the required quorum.

                                      -2-



     The  Company  will  bear  the  entire  cost  of   solicitation,   including
preparation,  assembling and mailing this proxy  statement,  the proxies and any
additional  material which may be furnished to  shareholders.  The Company will,
upon request,  reimburse the reasonable charges and expenses of brokerage houses
or other  nominees  or  fiduciaries  for  forwarding  proxy  materials  to,  and
obtaining authority to execute proxies from beneficial owners for whose accounts
they hold shares of Common Stock.  The original  solicitation of proxies by mail
may be  supplemented  by telephone,  telegram  and/or  personal  solicitation by
directors, officers or employees of the Company. No additional compensation will
be paid for such services.



SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT


     The following table sets forth certain information regarding the beneficial
ownership of the Company's  Common Stock as of April 7, 2006 by: (i) each person
who is known by the Company to own beneficially  more than 5% of the outstanding
shares of Common Stock; (ii) each of the Company's  executive  officers named in
the Summary Compensation Table; (iii) each of the Company's directors;  and (iv)
by all directors and executive  officers as a group.  In computing the number of
shares  beneficially  owned by a person and the  percentage of ownership of that
person,  shares of Common Stock  subject to options held by that person that are
currently  exercisable or exercisable within 60 days of April 7, 2006 are deemed
outstanding. Such shares, however, are not deemed outstanding for the purpose of
computing  the  percentage  ownership of each other  person.  The  percentage of
beneficial ownership is based on 4,151,954 shares of Common Stock outstanding as
of April 7, 2006. Except as otherwise  indicated,  the Company believes that the
beneficial owners of the securities listed below, based on information furnished
by such owners, have sole investment and voting power with respect to the Common
Stock shown as being beneficially owned by them:



       Directors, Nominees, Officers And 5% Stockholders      Shares Beneficially Owned     Percent Of Class
       -------------------------------------------------      -------------------------     ----------------
                                                                                          
   5% Stockholders
   ---------------

       Renovatio Global Funds, L.P. (4)                                                         15.8
                                                                   657,723

       Larry H. Schatz, L.P. ((5))                                                               7.2
                                                                   300,000

   Directors, Nominees, Officers
   -----------------------------

       William P. Horgan ((1))  ((3))                              175,733                       4.1

       Bernard I. Grosser, M.D.((2)) ((3))                                                       5.2
                                                                   218,850

       Helen C. Leong((2)) ((3))                                                                 3.5
                                                                   149,686

       Robert Marx((2)) ((3))                                                                    3.4
                                                                   142,684

       Greg Fredrick ((3))
                                                                         0                       0.0

   All executive officers and directors as                         686,953                      15.1
     a group (5 shareholders)


__________________________

(1)  Includes 118,000 shares issuable on exercise of outstanding options.

(2)  Includes 94,999 shares issuable on exercise of outstanding options.

(3)  Individuals may be contacted at the corporate  offices at 84 W. Santa Clara
     St., Suite 720, San Jose, CA 95113.

(4)  Fund may be contacted at 2221 Old Oakland Road, San Jose, CA 95131.

(5)  Individual may be contacted at 152 W. 57th Street, 31st Floor, New York, NY
     10019.


                                      -3-


PROPOSAL 1 -- ELECTION OF DIRECTORS


     Each of the four  directors  to be elected  will hold office until the next
annual  meeting of the  shareholders  or until a successor  shall be elected and
qualified. The following individuals are proposed for election:


Name                         Age       Position
- ----                         ---       --------
William P. Horgan            58        Chairman of the Board of Directors, Chief
                                       Executive Officer and Director

Bernard I. Grosser, MD       77        Director

Helen C. Leong               78        Director

Robert Marx                  75        Director



     William P. Horgan was  appointed  Chairman  of the Board in  November  1996
after serving as President,  Chief Executive  Officer and Director since January
1994, when he joined the Company.

     Bernard I.  Grosser,  MD has served as a Director  since  March  1992.  Dr.
Grosser is Chairman of the  Department of  Psychiatry at the  University of Utah
and has served in that capacity since 1982. Dr. Grosser has conducted  extensive
research related to hormonal target areas of the brain.

     Helen C. Leong has served as a Director since April 1993. Mrs. Leong is and
has been for more than five years the managing partner of Leong Ventures,  which
makes investments in the areas of biogenetics and health-oriented  technologies.
She is a general partner of CLW Associates, which specializes in real estate and
start-up  businesses  in  consumer  fields.  Mrs.  Leong  is also a  founder  of
Mid-Peninsula  Bank of Palo Alto where she has served as a director  since 1988.
Currently Mrs. Leong is a member of the Mid-Peninsula Bank Strategic Development
Board.

     Robert Marx has served as a Director  since October 1994.  Mr. Marx was the
founder  and  Co-Chief  Executive  Officer  of  Gildamarx  Incorporated,  a firm
specializing in designing and  manufacturing  exercise  apparel and products for
active  lifestyles  from 1979  until the sale of the  company  in 1996.  He is a
former member of the Executive  Committee of the Sports Apparel Products Council
and the Board of Directors of the California Manufacturers  Association,  and is
the Chairman of the Board of Governors for the City of Hope.


     There are no family  relationships among directors or executive officers of
the Company.


Required Vote
- -------------


     The nominee receiving the highest number of affirmative votes of the Common
Stock present or  represented  and entitled to be voted for them will be elected
as directors.


THE BOARD OF DIRECTORS  RECOMMENDS THAT THE SHAREHOLDERS VOTE "FOR" THE ELECTION
OF THE NOMINEES.

                                      -4-


Director Nomination
- -------------------

     Criteria for Board Membership.  In selecting  candidates for appointment or
re-election  to  the  Board,  the  current  Board  of  Directors  considers  the
appropriate balance of experience,  skills and  characteristics  required of the
Board  of  Directors,  and  seeks to  insure  that at  least a  majority  of the
directors  are  independent  under the rules of the Nasdaq  Stock  Market,  that
members  of the  Company's  audit  committee  meet the  financial  literacy  and
sophistication  requirements  under the rules of the Nasdaq  Stock Market and at
least one of them qualifies as an "audit committee  financial  expert" under the
rules of the  Securities  and  Exchange  Commission.  Nominees  for director are
selected  on the  basis of their  depth  and  breadth  of  experience,  industry
knowledge,   integrity,   ability  to  make  independent  analytical  inquiries,
understanding of the Company's business  environment,  and willingness to devote
adequate time to Board duties.

     Stockholder  Nominees.   The  Board  of  Directors  will  consider  written
proposals  from  stockholders  for nominees for director.  Any such  nominations
should be submitted to the Board of Directors  c/o the  Secretary of the Company
and should include the following  information:  (a) all information  relating to
such nominee that is required to be disclosed  pursuant to Regulation  14A under
the Securities  Exchange Act of 1934 (including such person's written consent to
being named in the proxy  statement as a nominee and to serving as a director if
elected);  (b) the names and addresses of the stockholders making the nomination
and the  number  of  shares  of the  Company's  common  stock  which  are  owned
beneficially   and  of  record  by  such   stockholders;   and  (c)  appropriate
biographical information and a statement as to the qualification of the nominee,
and should be submitted in the time frame described in the Bylaws of the Company
and under the caption, "Shareholder Proposals" below.

     Process for  Identifying  and Evaluating  Nominees.  The Board of Directors
believes the company is  well-served by its current  directors.  In the ordinary
course,  absent special  circumstances  or a material change in the criteria for
Board membership,  the nominating  committee will renominate incumbent directors
who  continue to be qualified  for Board  service and are willing to continue as
directors.  If an incumbent  director is not standing for  re-election,  or if a
vacancy on the Board occurs between annual stockholder  meetings,  and the Board
determines  the seat  should be  filled,  the Board of  Directors  will seek out
potential  candidates for Board  appointment who meet the criteria for selection
as a nominee and have the specific  qualities or skills being  sought.  Director
candidates  will be selected  based on input from  members of the Board,  senior
management of the company and, if the Board of Directors  deems  appropriate,  a
third-party  search firm. The Board of Directors will evaluate each  candidate's
qualifications and check relevant references;  in addition, such candidates will
be  interviewed  by at least one  member of the Board of  Directors.  Candidates
meriting serious consideration will meet with all members of the Board. Based on
this  input,  the Board of  Directors  will  evaluate  which of the  prospective
candidates  is  qualified  to serve  as a  director  and  whether  the  Board of
Directors  should  recommend  that this candidate be appointed to fill a current
vacancy on the Board,  or  presented  for the approval of the  stockholders,  as
appropriate.  The Company has never  received a proposal from a  stockholder  to
nominate a director.  Although the Board of  Directors  has not adopted a formal
policy with respect to stockholder nominees, the Board of Directors expects that
the evaluation process for a stockholder nominee would be similar to the process
outlined above.

Board Nominees for the 2006 Annual Meeting.  Each of the nominees listed in this
Proxy Statement are current directors standing for re-election.


Board Compensation
- ------------------


     Directors  currently are not compensated for attending Board meetings,  but
are  reimbursed  for their  reasonable  expenses  incurred  in  attendance.  The
Company's  2003  Non-Employee  Directors'  Stock  Option Plan (the "2003  Plan")
provides for the  automatic  grant of 20,000  shares of Common Stock if a person
who is  neither  an  officer  nor an  employee  of the  Company  and who has not
previously  been a member of the Board is elected or  appointed  director.  Each
such option will become  exercisable at the rate of one-twelfth of the number of
shares covered by the option each month following the grant date, so long as the
individual  is  serving  as a  director,  with full  vesting  over one year.  In
addition,  on the date of the first meeting of the Board  immediately  following
each annual meeting of stockholders  of the Company,  the Company is required to
grant to each non-employee  director a 10-year  Non-Qualified Option to purchase

                                      -5-


20,000  shares of the Company's  Common Stock at an exercise  price equal to the
fair market value of Common Stock on the date of the grant.  These  options will
vest one-twelfth per month after the date of grant, as long as the individual is
serving as a director,  with full vesting over one year.  The exercise  price of
all options  granted  pursuant to the 2003 Plan is the fair market  value of the
Company's  Common  Stock at the time of grant.  A total of  180,000  shares  are
reserved for issuance under the 2003 Plan.


Board Meetings and Committees of the Board
- ------------------------------------------


     The Board of Directors met six times in 2005, the audit committee met three
times  and  the   compensation   committee  held  one  meeting.   Each  director
participated  in at least 85% of the Board and  Committee  meetings  held during
2005.


     Nominating Committee


     The Company  does not have a standing  nominating  committee  due the small
size of the  Board.  Each  of the  current  Board  members  participates  in the
consideration of director nominees.


     Compensation Committee


     The  Compensation  and Stock Option  Committee  of the Board of  Directors,
whose members are Dr. Grosser,  Mrs. Leong and Mr. Marx, held one meeting during
2005, with all director  members in attendance at the meeting.  The Compensation
Committee is responsible for determining salaries, incentives and other forms of
compensation  for  officers and other  employees of the Company and  administers
various benefit plans.


     Audit Committee


     The current  members of the Audit  Committee of the Board of Directors  are
Dr. Grosser,  Mrs. Leong and Mr. Marx. The Board has determined that all members
of the audit committee are  independent  directors under the rules of the Nasdaq
Stock  Market  and  each of them is  able  to read  and  understand  fundamental
financial  statements.  The Board has determined that Mrs. Leong qualifies as an
"audit committee financial expert" as defined by the rules of the Securities and
Exchange  Commission.  The Audit  Committee's  purpose  is to  consult  with the
Company's  independent auditors concerning their audit plans, the results of the
audit,  the Company's  accounting  principles  and the adequacy of the Company's
general accounting controls.


     Communications With Directors


     Stockholders or other interested  parties may communicate with any director
or  committee  of the Board by writing to them c/o  Secretary,  Human  Pheromone
Sciences,  84 W. Santa Clara St., Suite 720, San Jose, CA 95113 or by sending an
e-mail to  secretary@erox.com.  Comments or questions  regarding  the  Company's
accounting, internal controls or auditing matters will be referred to members of
the Audit Committee. Comments or questions regarding the nomination of directors
and other corporate governance matters will be referred to the Board members.


     The Company has a policy of encouraging  all directors to attend the annual
shareholder meetings. All of the directors attended the 2005 annual meeting.


                                      -6-


                          REPORT OF THE AUDIT COMMITTEE


     The Audit Committee of the Board of Directors of Human Pheromone  Sciences,
Inc.  serves as the  representative  of the Board for general  oversight  of the
Company's  financial  accounting  and  reporting  process,  system  of  internal
controls,  audit process,  and process for monitoring  compliance  with laws and
regulations.  Each of the  members of the Audit  Committee  is  independent,  as
defined under the listing  standards of NASDAQ.  The committee  operates under a
written  charter  adopted  by the Board a copy of which was filed  with last the
2004  proxy  statement  as  Exhibit  A. The  Company's  management  has  primary
responsibility  for the system of internal  controls and preparing the Company's
financial  statements and for the Company's  financial  reporting  process.  The
Company's  independent  auditors,  Singer Lewak  Greenbaum & Goldstein  LLP, are
responsible for expressing an opinion on the conformity of the Company's audited
financial  statements to accounting  principles generally accepted in the United
States of America.


     In this context and in  connection  with the audited  financial  statements
contained in the Company's Annual Report on Form 10-KSB, the Audit Committee:

     o    reviewed  and  discussed  the audited  financial  statements  with the
          Company's  management,  including a  discussion  of the quality of the
          accounting principles;

     o    discussed  with Singer Lewak  Greenbaum & Goldstein LLP, the Company's
          independent  auditors,  their  judgment  as  to  the  quality  of  the
          Company's accounting principles, as well as certain matters related to
          the  conduct  of the audit,  as  required  by  Statement  of  Auditing
          Standards No. 61, "Communications with Audit Committees";

     o    met  with  the  independent  auditors,  with  and  without  management
          present,   to  discuss  the  results  of  their   examination,   their
          evaluations  of the  Company's  internal  controls,  and  the  overall
          quality of the Company's financial reporting;

     o    reviewed the written  disclosures  required by  Independence  Standard
          Board Standard No.1, "Independence Discussions with Audit Committees,"
          discussed with the auditors their  independence from the Company,  and
          concluded  that the  non-audit  services  performed  by  Singer  Lewak
          Greenbaum  &  Goldstein  LLP are  compatible  with  maintaining  their
          independence; and

     o    instructed the independent  auditors that the Committee  expects to be
          advised if there are any subjects that require special attention.


     Based  upon the  Audit  Committee's  discussions  with  management  and the
independent   accountants,   and  upon  the  Audit  Committee's  review  of  the
representations  of  management  and  the  independent  accountants,  the  Audit
Committee  recommended  to the Board of  Directors  that the  audited  financial
statements  for the fiscal  year ended  December  31,  2005 be  included  in the
Company's  Annual  Report on Form  10-KSB,  for filing with the  Securities  and
Exchange Commission.


         Audit Committee:

         Bernard I. Grosser, M.D.
         Helen Leong, Chairperson
         Robert Marx


                                      -7-


Principal Accountant Fees and Services


     Singer  Lewak  Greenbaum &  Goldstein  LLP was  retained  as the  Company's
independent  auditors  for the  years  ended  December  31,  2005 and  2004.  In
accordance   with  standard  policy  Singer  Lewak  Greenbaum  &  Goldstein  LLP
periodically change the individuals who are responsible for the Company's audit.

The following  table shows the fees paid or accrued by the Company for the audit
and other services provided by Singer Lewak Greenbaum & Goldstein LLP for fiscal
2005 and 2004.


                                     2005                     2004
                                     ----                     ----
          Audit Fees(1)            $ 64,602                $ 62,997

          Tax Fees(2)              $  8,262                $  8,627

(1)  Audit fees represent fees for professional  services provided in connection
     with the audit of the  Company's  financial  statements  and  review of the
     Company's  quarterly  financial  statement and audit  services  provided in
     connection with other statutory or regulatory filings.

(2)  Tax fees principally represents tax compliance services.


     The audit committee  reviews,  pre-approves the audit and tax fees proposed
by the Singer Lewak Greenbaum & Goldstein LLP in their annual engagement letter.
Singer Lewak  Greenbaum & Goldstein LLP did not provide any services  related to
financial information systems design and implementation during 2005.


     The Company  does not  anticipate  that  representatives  from Singer Lewak
Greenbaum & Goldstein, LLP will be present at the annual meeting.


EXECUTIVE COMPENSATION
- ----------------------


     The following  table sets forth the total  compensation  for 2005, 2004 and
2003 of the Chief Executive Officer and each of the other executive  officers of
the Company whose total salary and bonus for 2005 exceeded  $100,000 (the "Named
Officers").


                                            SUMMARY COMPENSATION TABLE


                                      Annual Compensation      Long-Term Compensation Award
                                      -------------------      ----------------------------
                                                             Restricted
                                                               Stock       Securities Underlying          Other
   Name and Principal Position         Year      Salary        Award             Options (#)          Compensation(A)
   ---------------------------         ----      ------        -----             -----------          ---------------
                                                                                            
William P. Horgan                      2005     $221,500         --                   --                   $ 18,000
Chairman  of  the  Board  and  Chief   2004     $225,250         --                   --                   $ 18,000
Executive Officer                      2003     $214,856      $6,500                  --                   $ 18,000

Gregory S. Fredrick                    2005     $116,000         --                   --                      --
Chief Financial Officer                2004     $121,700         --                   --                      --
                                       2003     $105,450         --                   --                      --

____________________

(A) Mr.  Horgan  receives an automobile  allowance of $18,000 per year,  payable
semimonthly.

                                      -8-


Stock Options Granted in the Fiscal Year Ended December 31, 2005


     No stock  options were  granted to the Named  Officers  during  fiscal year
2005.


Aggregated  Option  Exercises  in Last  Fiscal  Year and Fiscal  Year End Option
Values


     The following table sets forth certain information concerning the number of
unexercised options held as of December 31, 2005 by the Named Officers.

                          Number of Securities
                         Underlying Unexercised          Value of Unexercised
                               Options at              In-the-Money Options at
                            December 31, 2005             December 31, 2005
        Name            Exercisable/Unexercisable     Exercisable/Unexercisable
        ----            -------------------------     -------------------------
                                   (#)                         ($)(1)
                                   ---                         ------

  William P. Horgan            118,000 / 0                    $ 0 / $ 0

_______________________

(1)  Assuming a stock price of $0.20 per share, which was the closing price of a
     Share of Common Stock  reported on the OTC  Bulletin  Board on December 31,
     2005.


EQUITY COMPENSATION PLAN INFORMATION



                                                                                                   Number of remaining
                                          Number of securities                                    available for future
                                            to be issued upon          Weighted-average           issuance under equity
                                               exercise of           exercise price of        compensation plans(excluding
                                          outstanding options,      outstanding options,         securities reflected in
      Equity Compensation Plans            warrants and rights      warrants and rights                column(a))
      -------------------------            -------------------      -------------------                ----------
                                                                                               
Equity compensation plans approved by
security holders                                188,000                    $ 1.03                           --

Equity compensation plans not
approved by security holders                    180,000                    $ 0.38                        120,000




DESCRIPTION OF PLANS NOT APPROVED BY SHAREHOLDERS


     On June 25,  2003 the  Board of  Directors  adopted  the 2003  Non-employee
Directors Stock Option Plan (the "2003 Plan") of Human Pheromone Sciences,  Inc.
A maximum of 300,000  shares of commons  stock may be issued on  exercise of the
Options granted pursuant to the 2003 Plan. The 2003 Plan will expire on June 24,
2010.  This plan replaces the  Directors'  Plan which expired June 13, 2003. The
2003 Plan  provides for annual  grants of options to purchase  20,000  shares of
common  stock to each  non-employee  director at an exercise  price equal to the
fair market value of the stock on the date of the grant.


                                      -9-



SECTION 16(a) BENEFICIAL OWNERSHIP


     Section 16(a) of the Securities Exchange Act of 1934, as amended,  requires
the Company's  directors and executive  officers,  and persons who own more than
10% of the  outstanding  shares of the Company's  Common Stock, to file with the
Securities and Exchange  Commission  initial  reports of ownership  (Form 3) and
changes in ownership of such stock (Forms 4 and 5).


     To the Company's knowledge,  based solely upon review of the copies of such
reports and certain  representations  furnished to it, all Section  16(a) filing
requirements  applicable to its executive  officers and directors  were complied
with during the year ended December 31, 2005.


OTHER BUSINESS


     The Board of  Directors  knows of no business  that will be  presented  for
consideration  at the  Annual  Meeting  other  than as stated  in the  Notice of
Meeting. If, however,  other matters are properly brought before the meeting, it
is the intention of the persons named in the accompanying  form of proxy to vote
the shares  represented  thereby on such matters in  accordance  with their best
judgment.


SHAREHOLDER PROPOSAL


     Under the rules of the Securities and Exchange Commission, shareholders who
wish to submit  proposals  for  inclusion in the Proxy  Statement for the Annual
Meeting of  Shareholders  to be held in 2007 must submit such proposals so as to
be received by the Company at 84 West Santa Clara  Street,  Suite 720, San Jose,
California 95113 not later than January 20, 2007.


                                  BY ORDER OF THE BOARD OF DIRECTORS


                                          Julian N. Stern, Secretary


San Jose, California
April 24, 2006


                                    IMPORTANT


     You are cordially  invited to attend the meeting in person.  Whether or not
you plan to attend the meeting,  you are earnestly  requested to sign and return
the accompanying proxy in the enclosed envelope.


                                      -10-


                                                                      APPENDIX A

                       ANNUAL MEETING OF SHAREHOLDERS OF
                         HUMAN PHEROMONE SCIENCES, INC.
                                 JUNE 21, 2006

                           Please date, sign and mail
                             your proxy card in the
                           envelope provided as soon
                                  as possible.

Please detach along perforated line and mail in the envelope provided.

- --------------------------------------------------------------------------------
THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR" THE ELECTION OF DIRECTORS. PLEASE
SIGN, DATE AND RETURN PROMPTLY IN THE ENCLOSED  ENVELOPE.  PLEASE MARK YOUR VOTE
IN BLUE OR BLACK INK AS SHOWN HERE [X]
- --------------------------------------------------------------------------------

1. To elect four Directors to hold office until the next Annual Meeting;


                                               NOMINEES
[_] FOR ALL NOMINEES                           (_) William P. Horgan
[_] WITHHOLD AUTHORITY                         (_) Bernard I. Grosser, M.D.
    FOR ALL NOMINEES                           (_) Helen C. Leong
[_] FOR ALL EXCEPT                             (_) Robert Marx
    (See instructions below)


INSTRUCTION:
To  withhold  authority  to vote for any  individual  nominee(s),  mark "FOR ALL
EXCEPT" and fill in the circle next to each  nominee  you wish to  withhold,  as
shown here: (*)


2. To act upon such other business as may properly come before the meeting.

These  items of  business  are  more  fully  described  in the  Proxy  Statement
accompanying this notice.

Only  shareholders  of  record at the close of  business  on April 28,  2006 are
entitled to notice of, and to vote at the Annual Meeting and any adjournments or
postponements thereof.

All shareholders are cordially invited to attend the meeting in person. However,
to assure your representation at the meeting, please mark, sign, date and return
the enclosed proxy card as soon as possible in the postage-prepaid envelope
enclosed for that purpose. Any shareholder attending the meeting may vote in
person even if the shareholder has returned a proxy.

WHETHER OR NOT YOU EXPECT TO ATTEND THE ANNUAL MEETING IN PERSON, PLEASE SIGN
AND RETURN THE ENCLOSED PROXY AS SOON AS POSSIBLE IN THE ENCLOSED POSTPAID
ENVELOPE. THAT YOU FOR ACTING PROMPTLY.

- --------------------------------------------------------------------------------
To change the address on your account, please check the box at right
and indicate your new address in the address space above. Please note
that changes to the registered name(s) on the account may not be
submitted via this method. [_]
- --------------------------------------------------------------------------------


Signature of Shareholder [                  ]         Date [               ]

Signature of Shareholder [                  ]         Date [               ]


Note:  Please  sign  exactly as your name or names  appear on this  Proxy.  When
shares are held  jointly,  each holder  should  sign.  When signing as executor,
administrator, attorney, trustee or guardian, please give full title as such. If
the signer is a corporation,  please sign full corporate name by duly authorized
officer,  giving full title as such. If signer is a partnership,  please sign in
partnership name by authorized person.



                         HUMAN PHEROMONE SCIENCES, INC.

               PROXY SOLICITED BY THE BOARD OF DIRECTORS FOR THE
            ANNUAL MEETING OF SHAREHOLDERS TO BE HELD JUNE 21, 2006

     The  annual  meeting  of  shareholders  (the  "Annual  Meeting")  of  Human
Pheromone Sciences, Inc. (the "Company" or "HPS") will be held at the offices of
Heller Ehrman LLP, 275 Middlefield  Road,  Menlo Park,  California,  on June 21,
2006, at 10:00 am local time, for the fillowing purposes:

                (Continued and to be signed on the reverse side)