EMPLOYMENT AGREEMENT


         This Employment Agreement (the "Agreement") is entered into February 1,
1996  between  SciClone  Pharmaceuticals,  Inc. a California  corporation,  (the
"Company"), and Donald R. Sellers, an individual ("Employee").

         In consideration of the promises and the terms and conditions set forth
in this Agreement, the parties agree as follows:

1.  Position.  During  the  term of this  Agreement,  the  Company  will  employ
Employee,  and Employee  will serve the Company as its  President  and will have
such other  responsibilities,  authority  and titles as may from time to time be
assigned to Employee by the Board of Directors of the Company.

2.  Duties.  Employee  will  have  the  duties  and  responsibilities  generally
associated  with the positions held by Employee and as the Board of Directors of
the Company may from time to time  determine.  Employee  will comply with and be
bound by Company's  operating policies,  procedures,  and practices from time to
time in effect during  Employee's  employment.  Employee  hereby  represents and
warrants that he is free to enter into and fully perform this  Agreement and the
agreements  referred to herein  without  breach of any  agreement or contract to
which he is a party or by which he is bound.

3.       Compensation and Benefits.

         3.1 Base  Salary.  The Company  agrees to pay Employee a base salary of
$400,000.  The base  salary  shall be  payable  as  earned  in  accordance  with
Company's  customary payroll practice.  If this Agreement is renewed pursuant to
Section 4,  Employee's  base salary for future years shall be  negotiated by the
Company and Employee.

         3.2 Cash Bonus.  The Company agrees to pay Employee a bonus of $200,000
upon the full  achievement  of  specified  goals agreed upon by Employee and the
Company.  The bonus shall be payable in accordance with the Company's  customary
bonus payment practices unless otherwise agreed by the Company and Employee.  If
this Agreement is renewed pursuant to Section 5, Employee's future bonus targets
and goals shall be negotiated by the Company and Employee.

         3.3 Cost-of-Living Assistance Payments. The Company (or a subsidiary of
the Company) agrees to continue the cost-of-living  assistance payments Employee
received as Managing  Director,  Pacific Rim  Operations of the Company at their
current level through July 31, 1996.

         3.4 Car  Allowance.  Employee  will receive a car allowance of $850 per
month.

         3.5  Additional  Benefits.  Employee will be eligible to participate in
the Company's employee benefit plans of general  application,  including without
limitation  those plans covering  pension and profit sharing,  stock  purchases,
stock options,  and those plans covering life,  health,





and dental  insurance in accordance  with the rules  established  for individual
participation  in any such plan and applicable  law.  Employee will receive such
other  benefits,  including  vacation,  holidays and sick leave,  as the Company
generally provides to its employees holding similar executive  positions as that
of Employee.

         3.6 Expenses.  The Company will  reimburse  Employee for all reasonable
and necessary  expenses  incurred by Employee in  connection  with the Company's
business,  provided  that such  expenses are in  accordance  with the  Company's
applicable  policy and are properly  documented  and accounted for in accordance
with the requirements of the Internal Revenue Service.

4.       Term and Termination.

         4.1 Term.  This Agreement shall terminate 12 months from the date first
entered into above (the  "Anniversary  Date") unless  renewed by the Company and
Employee.

         4.2  Events of  Termination.  The  Agreement  may  terminated  upon the
occurrence of any one of the following events:

                  (a) The Company's  determination made in good faith that it is
terminating Employee for "cause" (as defined herein) ("Termination for Cause").

                  (b)  The  Company's   determination  that  it  is  terminating
Employee without "cause" (as defined herein), which determination may be made by
the Company at any time at the Company's sole discretion,  for any reason or for
no reason ("Termination Without Cause").

                  (c) The effective date of a written notice sent to the Company
from Employee stating that Employee is electing to terminate his employment with
the Company ("Voluntary Termination").

         4.3  "Cause"  Defined.  For  purposes  of this  Agreement,  "cause" for
Employee's termination will exist at any time after the happening of one or more
of the following events:

                  (a)  Employee's  willful  misconduct  or gross  negligence  in
performance of his duties hereunder,  inducing  Employee's  refusal to comply in
any  material  respect  with the  legal  directives  of the  Company's  Board of
Directors so long as such  directives are not  inconsistent  with the Employee's
position and duties,  and such refusal to comply is not remedied within ten (10)
working days after written notice from Company, which written notice shall state
that failure to remedy such conduct may result in Termination for Cause.

                  (b) Dishonest or fraudulent  conduct,  a deliberate attempt to
do an injury to the Company,  or conduct that materially  discredits the Company
or is materially detrimental to the reputation of the Company.

                  (c) Employee's incurable material breach of any element of the
Company's Proprietary  Information and Inventions  Agreement,  including without
limitation,   Employee's  theft  or  other  misappropriation  of  the  Company's
proprietary information.

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         4.4 "Disability" Defined. For purposes or this Agreement,  "disability"
will mean that the Board of Directors has determined, based on competent medical
evidence,  that the Employee has become  incapable,  mentally or physically,  of
substantially performing his services and discharging his duties hereunder for a
period in excess of six (6) months.

5.       Effect of Termination.

         5.1 Termination for Cause or Voluntary Termination. In the event of any
termination of this Agreement pursuant to Sections 4.2(a) or 4.2(c), the Company
shall pay Employee the compensation and benefits  otherwise  payable to Employee
under  Section 3 through the date of  termination.  Employee's  rights under the
Company's  benefit plans of general  application  shall be determined  under the
provisions of those plans.

         5.2 Termination  Without Cause. In the event of any termination of this
Agreement pursuant to Section 4.2(b), or as a result of a material diminution of
Employee's  duties  and  responsibilities  by the  Company,  or as a  result  of
Employee's death or disability (as defined herein),

                  (a) the  Company  shall  pay  Employee  the  compensation  and
benefits  otherwise  payable to  Employee  under  Section 3 through  the date of
termination,  except that  health-related  benefits  shall continue for one year
beyond the effective date of termination.

                  (b) within seven (7) days of  termination,  Company  shall pay
Employee  a  severance  payment  equal to the sum of one  year of the  Employees
then-current base salary, car allowance and the bonus Employee could have earned
had he  continued  employment  with the Company  through the end of the calendar
year in which termination occurs,

                  (c) the Company shall cause all of the Employee's  outstanding
stock  options  to become  immediately  vested and the  exercise  period of such
options will be extended for a period of one year, provided,  however, that such
extension shall not exceed the original term of such options, and

                  (d)  Employee's  rights under the  Company's  benefit plans of
general application shall be determined under the provisions of those plans.

6.       Miscellaneous.

         6.1 Severability.  If any provision of this Agreement shall be found by
any   arbitrator   or  court  of  competent   jurisdiction   to  be  invalid  or
unenforceable,  then the parties  hereby waive such provision to the extent that
it is found to be invalid or unenforceable and to the extent that to do so would
not deprive one of the parties of the substantial  benefit of its bargain.  Such
provision shall, to the extent allowable by law and the preceding  sentence,  be
modified by such arbitrator or court so that it becomes  enforceable  consistent
with the intent of this  Agreement  and, as  modified,  shall be enforced as any
other provision  hereof,  all the other provisions  continuing in full force and
effect.

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         6.2 No  Waiver.  The  failure  by either  party at any time to  require
performance  or compliance by the other of any of its  obligations or agreements
shall in no way affect the right to require such  performance  or  compliance at
any time  thereafter.  The waiver by either  party of a breach of any  provision
hereof shall not be taken or held to be a waiver of any  preceding or succeeding
breach of such  provision or as a waiver of the provision  itself.  No waiver of
any kind shall be effective or binding, unless it is in writing and is signed by
the party against whom such waiver is sought to be enforced.

         6.3 Assignment. This Agreement and all rights hereunder are personal to
Employee  and may not be  transferred  or assigned by Employee at any time.  The
Company may assign its rights,  together with its obligations hereunder,  to any
parent,  subsidiary,  affiliate or successor,  or in  connection  with any sale,
transfer or other  disposition of all or  substantially  all of its business and
assets,  provided,  however,  that  any  such  assignee  assumes  the  Company's
obligations hereunder.

         6.4  Withholding.  All sums  payable  to  Employee  hereunder  shall be
reduced by all federal, state, local and other withholding and similar taxes and
payments required by applicable law.

         6.5  Amendment.  This Agreement may be amended,  modified,  superseded,
canceled,  renewed or extended only by an agreement in writing  executed by both
parties hereto.

         6.6 Notices. All notices and other communications required or permitted
under this Agreement shall be in writing and hand delivered, sent by telecopier,
sent by certified  first class mail,  postage  pre-paid,  or sent by  nationally
recognized express courier service.  Such notices and other communications shall
be effective upon receipt if hand delivered or sent by telecopier, five (5) days
after mailing if sent by mail, and one (1) day after dispatch if sent by express
courier, to the following addresses, or such other addresses as any party, shall
notify the other parties:

        If to the Company:        SciClone Pharmaceuticals, Inc.
                                  901 Mariners Island Blvd.
                                  San Mateo, CA 94404
                                  Attention:  Chairman of the Board of Directors
                                  Telecopier: (415) 358-3469

        If to Employee:           Donald R. Sellers
                                  c/o SciClone Pharmaceuticals, Inc.
                                  901 Mariners Island Boulevard
                                  San Mateo, CA 94404
                                  Telecopier: (415) 358-3469

         6.7 Binding Nature.  This Agreement shall be binding upon, and inure to
the benefit of, the  successors and personal  representatives  of the respective
parties hereto.

         6.8  Headings.  The  headings  contained  in  this  Agreement  are  for
reference purposes only and shall in no way affect the meaning or interpretation
of this Agreement.  In this 

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Agreement,  the singular includes the plural,  the plural included the singular,
the masculine gender includes both male and female referents,  and the word "or"
is used in the inclusive sense.

         6.9  Counterparts.  This  Agreement  may be  executed  in  two or  more
counterparts,  each of which shall be deemed to be an original but all of which,
taken together, constitute one and the same agreement.

         6.10 Governing  Law. This  Agreement and the rights and  obligations of
the parties  hereto shall be construed in accordance  with the laws of the State
of California, without giving effect to the principles of conflict of laws.


         IN WITNESS  WHEREOF,  the  Company  and  Employee  have  executed  this
Agreement as of the date first above written.

SCICLONE PHARMACEUTICALS, INC.              EMPLOYEE


By: ____________________________            ______________________________
                                            Donald R. Sellers

Name:___________________________


Title:__________________________



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