CHOLESTECH LOGO
November 14, 1996



Andrea J. Tiller

Dear Andrea:

I know I speak  for our  Board of  Directors,  as well as the  entire  team,  in
extending  our  invitation  to join  Cholestech on December 2, 1996, as our Vice
President of Finance and Chief Financial  Officer. I would like to formalize our
discussions  about  cash  compensation, benefits,  and  equity  opportunity,  as
follows:

CASH COMPENSATION

     o   Salary  of  $125,000  base  per  annum  to be  reviewed  each  February
         beginning 1998.
     o   You will  participate  in the Management  Incentive  Program when it is
         established.
     o   You will be given an  six-month  severance  package,  effective 90 days
         after your start date.

BENEFITS

Participation in Cholestech Associates' benefits package which includes:


     o   Medical and dental plan
     o   Life insurance at one time your annual salary
     o   Long-term disability
     o   Sixteen (16) days of Personal Time Off (PTO) the first year.
     o   Ten (10) paid holidays per year.
     o   Participation in Cholestech's 401(k) Retirement Savings Plan

Information  regarding  these  programs and other  Company  benefits  along with
guidelines  concerning  employment  are  contained in the  Cholestech  Associate
package, which is issued at the time employment commences.

EQUITY

     Incentive  Stock Options for 60,000 shares of common stock to be granted at
     the next  meeting of our Board of  Directors.  The stock  price will be the
     closing  price on the NASDAQ as of that date.  After one year of employment
     you will be eligible to exercise 25% of your incentive stock option shares,
     and  thereafter  an  additional  6.25% of the shares per  quarter  over the
     second through fourth years of employment.

All  new   Associates  are  required  to  sign  an   "Employment,   Confidential
Information,  Invention Assignment,  and Arbitration  Agreement" prepared by our
attorneys  as  a  condition  of  employment.  Review  the  enclosed  Employment,
Confidential Information,  Invention Assignment, and Arbitration Agreement form.
Please  wait to  sign  this  agreement  in the  presence  of a  Cholestech  Vice
President or Human Resource Personnel.

                             CHOLESTECH CORPORATION
                           3347 INVESTMENT BOULEVARD
                             HAYWARD, CA 94545-3808
                       (510) 732-7200 FAX (510) 732-7227


Andrea J. Tiller
November 14, 1996
Page Two

Andrea, we are exited at the prospect of having you join us as Vice President of
Finance  and  Chief  Financial  Officer.  Please  feel  free to call me with any
questions or comments you might have about the offer and to discuss.

I look  forward  to  working  with you and  having  you as a key  member  of the
Cholestech senior management team.

Best regards,                                 Accepted by:


/s/ Warren E. Pinckert II                      /s/ Andrea J. Tiller
- --------------------------------------        ---------------------------------
Warren E. Pinckert II                         Andrea J. Tiller
President and Chief Executive Officer

                                                  11/15/96
                                              ---------------------------------
                                              Date

cc:   Jack Castello
      Terry Thomas

Enclosure:   Employment, Confidential Information, Invention Assignment,
               and Arbitration Agreement.