EXHIBIT 15


Cambridge Antibody Technology Group plc                 Oxford Glycosciences plc
Milstein Building                                                      The Forum
Granta Park                                                       86 Milton Park
Cambridge                                                               Abingdon
CB1 6GH                                                             Oxfordshire
                                                                        OX14 4RY


22 January 2003

Dear Sirs,

Project Boat

1.    In this letter "Bidder" means Cambridge Antibody Technology Group plc,
      "Target" means Oxford Glycosciences plc, "Party" means either Bidder or
      Target and "Parties" means both of them. Also, in this letter,
      "Transaction" means the proposed combination of Target with Bidder which
      is to be effected by way of a scheme of arrangement substantially on the
      terms and subject to the conditions set out in the attached draft press
      announcement (subject to any modification thereto as may be agreed between
      any director of Bidder and any director of Target, and together with any
      such additional terms and conditions as may be required to comply with the
      requirements of the Listing Rules made by the competent authority under
      the Financial Services and Markets Act 2000 or the rules and regulations
      of London Stock Exchange plc or the City Code on Takeovers and Mergers).

2.    In consideration of their mutual obligations under this letter, the
      Parties agree as follows:

      (a)   the Target shall pay to the Bidder (pound)1,096292, forthwith, in
            the event that:

            (i)   the Target's shareholders fail to pass any shareholder
                  resolution required to implement the Transaction; or

            (ii)  the Target's board of directors fails to recommend or
                  withdraws or modifies its recommendation of the Transaction or
                  fails to take any steps which are necessary to implement the
                  Transaction (including failing to put any shareholders
                  resolutions to the vote or adjourning or permitting the
                  adjournment of any meetings at which such resolutions are to
                  be put);

            except where the provisions of clause 4 of the Transaction Agreement
            between Target and Bidder dated 22 January 2003 (the "Transaction
            Agreement") apply; and

      (b)   the Bidder shall pay to the Target (pound)1,096292, forthwith, in
            the event that:

            (i)   the Bidder's shareholders fail to pass any shareholder
                  resolution required to implement the Transaction; or

            (ii)  the Bidder's board of directors fails to recommend or
                  withdraws or modifies its recommendation of the Transaction or
                  fails to take any steps which are necessary to implement the
                  Transaction (including failing to put any shareholders
                  resolutions to the vote or adjourning or permitting the
                  adjournment of any meetings at which such resolutions are to
                  be put);

      except where the provisions of clause 4 of the Transaction Agreement
      apply.





3.    No delay in exercising or non-exercise of any right, power or remedy
      provided by law or under or in connection with this letter shall impair,
      or otherwise operate as a waiver or release of, that right, power or
      remedy.

4.    If all or any part of any provision of this letter shall be or become
      illegal, invalid or unenforceable in any respect, then the remainder of
      that provision and/or all other provisions of this letter shall remain
      valid and enforceable and the remaining obligations of the parties under
      this letter shall not be affected or impaired.

5.    This letter shall be governed by and construed in accordance with the laws
      of England.

Yours faithfully,


/s/ [ILLEGIBLE]
- ------------------------------------
Director for and on behalf of Cambridge Antibody Technology Group plc



- ------------------------------------
Director for and on behalf of Oxford Glycosciences plc