Exhibit 99.1

                            CERTIFICATION PURSUANT TO
                               18 U.S.C.ss.1350,
                             AS ADOPTED PURSUANT TO
                 SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Annual Report of OraSure Technologies, Inc. (the
"Company") on Form 10-K for the year ended December 31, 2002 as filed with the
Securities and Exchange Commission on the date hereof (the "Report"), I, Michael
J. Gausling, President and Chief Executive Officer of the Company, certify,
pursuant to 18 U.S.C. ss.1350, as adopted pursuant to Section 906 of the
Sarbanes-Oxley Act of 2002, that:

         (1) The Report fully complies with the requirements of Section 13(a) or
15(d) of the Securities Exchange Act of 1934; and

         (2) The information contained in the Report fairly presents, in all
material respects, the financial condition and results of operations of the
Company.


/s/ Michael J. Gausling


Michael J. Gausling
President and Chief Executive Officer

March 31, 2003

A signed original of this written statement required by Section 906 of the
Sarbanes-Oxley Act of 2002 has been provided to OraSure Technologies, Inc. and
will be retained by OraSure Technologies, Inc. and furnished to the Securities
and Exchange Commission or its Staff upon request.