EXHIBIT 4.2
 
THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE
HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF A DEPOSITARY OR A
NOMINEE OF A DEPOSITARY.  THIS SECURITY IS EXCHANGEABLE FOR SECURITIES
REGISTERED IN THE NAME OF A PERSON OTHER THAN THE DEPOSITARY OR ITS NOMINEE ONLY
IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE AND MAY NOT BE
TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF SUCH DEPOSITARY
OR BY A NOMINEE OF SUCH DEPOSITARY TO SUCH DEPOSITARY OR ANOTHER NOMINEE OF SUCH
DEPOSITARY OR BY SUCH DEPOSITARY OR ANY SUCH NOMINEE TO A SUCCESSOR OF SUCH
DEPOSITARY OR A NOMINEE OR SUCH SUCCESSOR.

Unless this certificate is presented by an authorized representative of The
Depository Trust Company, a New York corporation ("DTC"), to the Company or its
agent for registration of transfer, exchange or payment, and any certificate
issued is registered in the name of Cede & Co. or in such other name as is
requested by an authorized representative of DTC (and any payment is made to
Cede & Co. or to such other entity as is requested by an authorized
representative of DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR
OTHERWISE BY OR TO ANY PERSON IS WRONGFUL inasmuch as the registered owner
hereof, Cede & Co., has an interest herein.



                                                                Principal Amount

                      COLUMBIA/HCA HEALTHCARE CORPORATION           $200,000,000

                     7.50% DEBENTURE DUE NOVEMBER 15, 2095

                               GLOBAL DEBENTURE

                                                                 Cusip 197677AHO


     COLUMBIA/HCA HEALTHCARE CORPORATION, a corporation duly organized and
existing under the laws of the State of Delaware (herein called the "Company",
which term includes any successor corporation under the Indenture hereinafter
referred to), for value received, hereby promises to pay to Cede & Co., as the
nominee of The Depository Trust Company, or registered assigns, the principal
amount of Two Hundred Million Dollars ($200,000,000), on November 15, 2095 (the
"Maturity Date") and to pay interest (computed on the basis of a 360-day year of
twelve 30-day months) on May 15 and November 15 ("Interest Payment Date") in
each year, beginning on May 15, 1996, and at the Maturity Date specified above
on said principal amount, at the rate of 7.50% per annum, from November 15, 1995
until payment of said principal amount has been made or duly provided for.  The
interest so payable on any Interest Payment Date (other than at maturity) will
be paid to the Person in whose name

 
this Global Debenture is registered at the close of business on the last day of
the month immediately preceding the month in which such interest payment is due
(a "Regular Record Date"), next preceding such Interest Payment Date, unless the
Company shall default in the payment of interest due on any such Interest
Payment Date, in which case such defaulted interest shall be paid to the Person
in whose name this Global Debenture is registered at the close of business on a
Special Record Date for the payment of such defaulted interet established by
notice to the registered holders of Debentures not less than ten days preceding
such Special Record Date.  In any case where the date for any payment on the
Debentures is not a Business Day, such payment shall be made on the next
succeeding Business Day.  A Business Day is any day that is not a Saturday or
Sunday and that, in Chicago, Illinois, is not a day on which banking
institutions are generally authorized or required by law or executive order to
close.

     Both principal of and interest on this Global Debenture are payable in
immediately available funds in any coin or currency of the United States of
America, which at the time of payment is legal tender for the payment of public
and private debts.  Payments of principal and interest will be made in Chicago,
Illinois, at the Corporate Trust Office of The First National Bank of Chicago,
or at such other office or agency of the Company as the Company shall designate
pursuant to the Indenture referred to elsewhere herein.

     This Global Debenture is one of a duly authorized issue of debentures,
notes, bonds or other evidences of indebtedness of the Company (hereinafter
called the "Securities"), of the series hereinafter specified, issued or to be
issued under an Indenture dated as of December 15, 1993, as may be amended by
indentures supplemental thereto (hereinafter called the "Indenture"), duly
executed and delivered by the Company to The First National Bank of Chicago, as
trustee (hereinafter called the "Trustee"), to which Indenture reference is
hereby made for a description of the respective rights and duties thereunder of
the Trustee, the Company and the Holders of the Securities.  The Securities may
be issued in one or more series, which different series may be issued in various
aggregate principal amounts, may mature at different times, may bear interest at
different rates, may have different conversion prices (if any), may be subject
to different redemption provisions, may be subject to different sinking,
purchase or analogous funds, may be subject to different covenants and Events of
Default and may otherwise vary as in the Indenture provided.  This Global
Debenture is a Global Security representing the entire principal amount of a
series of Securities designated "7.50% Debentures due November 15, 2095"
(hereincalled the "Debentures") issued under the Indenture.  Unless otherwise
provided herein, all terms used in this Global Debenture, which are defined in
the Indenture shall have the meanings assigned to them in the Indenture.

     The Debentures do not have a sinking fund.

     The Debentures may not be redeemed by the Company prior to maturity.

     In case an Event of Default with respect to the Debentures shall have
occurred and be continuing, the principal hereof may be declared, and upon such
declaration shall become, immediately due and payable, in the manner, with the
effect and subject to the conditions

                                       2

 
provided in the Indenture.  The Indenture provides that such declaration may in
certain events be waived by the Holders of a majority in principal amount of the
Debentures then Outstanding.

     The Indenture permits, with certain exceptions as therein provided, the
amendment thereof and the modification of the rights and obligations of the
Company and the rights of the Holders of the Securities of each series to be
affected under the Indenture at any time by the Company and the Trustee with the
consent of the Holders of not less than a majority in principal amount of the
outstanding Securities of each series to be affected.  It is also provided in
the Indenture that prior to any declaration accelerating the maturity of the
Debentures as a series, the Holders of a majority in aggregate principal amount
of the Securities of such series at the time Outstanding may on behalf of the
Holders of all of the Securities of such series waive any past default with
respect to the Securities of such series under the Indenture and its
consequences, except a default in the payment of the principal of, or interest
on, any of the Securities of such series.

     No reference herein to the Indenture and no provision of this Global
Debenture or of the Indenture (including the Company's right to defease and
discharge the Debentures pursuant to Article Four and Article Fourteen of the
Indenture) shall alter or impair the obligation of the Company, which is
absolute and unconditional, to pay the principal of, and interest on, this
Global Debenture at the place, at the respective times, at the rate and in the
coin or currency herein prescribed.

     This Global Debenture shall be exchangeable for Securities registered in
the names of Persons other than the Depositary or its nominee only if (i) the
Depositary notifies the Company that it is unwilling or unable to continue as
the Depositary or if at any time the Depositary ceases to be registered or in
good standing under the United States Securities Exchange Act of 1934, as
amended, and the Company fails to appoint a successor Depositary within 90 days
after the Company receives such notice or becomes aware of such event, (ii) the
Company executes and delivers to the Trustee a Company Order that this Global
Debenture shall be so exchangeable or (iii) there shall have occurred and be
continuing an Event of Default, or an event which, with the giving of notice or
the lapse of time, or both, would constitute an Event of Default, with respect
to the Debentures.  To the extent that this Global Debenture is exchangeable
pursuant to the preceding sentence, it shall be exchangeable for Debentures
registered in such names as the Depositary shall direct.

     Except as provided in the immediately preceding paragraph, this Global
Debenture may not be transferred except as a whole by the Depositary to a
nominee of such Depositary or by a nominee of such Depositary to such Depositary
or another nominee of such Depositary or by such Depositary or any such nominee
to a successor of such Depositary or a nominee of such successor.

     Prior to due presentment for registration of transfer of this Global
Debenture, the Company, the Trustee and any agent of the Company or the Trustee
may deem and treat the Holder hereof as the absolute owner of this Global
Debenture (whether or not this Global Debenture shall be overdue and
notwithstanding any notation of ownership or other writing hereon), for the
purpose of receiving payment hereof or on account hereof (except as otherwise

                                       3

 
provided in the Indenture), as herein provided, and for all other purposes, and
neither the Company nor the Trustee nor any Paying Agent nor any Security
Registrar shall be affected by any notice to the contrary.  All payments made to
or upon the order of such Holder shall, to the extent of the sum or sums paid,
effectually satisfy and discharge liability for moneys payable on this Global
Debenture.

     None of the Company, the Trustee, any Paying Agent or the Security
Registrar will have any responsibility or liability for any aspect of the
records relating to or payments made on account of beneficial ownership
interests of this Global Debenture or for maintaining, supervising or reviewing
any records relating to such beneficial ownership interests.

     No recourse for the payment of the principal of, or interest on, this
Global Debenture, or for any claims based hereon or otherwise in respect hereof,
and no recourse under or upon any obligation, covenant or agreement of the
Company in the Indenture or any indenture supplemental thereto or in any
Debenture or because of the creation of any indebtedness represented thereby,
shall be had against any incorporator, stockholder, officer or director, as
such, past, present or future, of the  Company, whether by virtue of any
assessment or penalty or otherwise, all such liability being, by the acceptance
hereof and as part of the consideration for the issue hereof, expressly waived
and released.

     Except as otherwise expressly provided in this Global Debenture, this
Global Debenture shall in all respects be entitled to all benefits, and subject
to the same terms and conditions, as definitive registered securities
authenticated and delivered under the Indenture.

     The Indenture and this Global Debenture shall be governed by and construed
in accordance with the laws of the State of New York.

     This Global Debenture shall not be valid or become obligatory for any
purpose until the certificate of authentication hereon shall have been signed by
the Trustee under the Indenture referred to on the reverse hereof.

                                       4

 
     IN WITNESS WHEREOF, the Company has caused this instrument to be duly
executed under its corporate seal.


Dated as of November 27, 1995               COLUMBIA/HCA HEALTHCARE           
                                             CORPORATION                      
                                                                              
                                                                              
TRUSTEE'S CERTIFICATE                       By:_______________________________
OF AUTHENTICATION                           Title:____________________________
                                                                              
This is one of the Securities               Attest:___________________________
of the series designated herein             Title:____________________________
referred to in the within-
mentioned Indenture.

THE FIRST NATIONAL BANK OF CHICAGO,
as Trustee


By:______________________________

                                       5