EXHIBIT 23


              CONSENT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS


We consent to the incorporation by reference in the Registration Statement (Form
S-8 No. 33-43981 and Form S-8 No. 33-63456) pertaining to the Stock Option Plans
of U.S. Bioscience, Inc., the Registration Statement (Form S-3 No. 33-77376) and
related prospectus of U.S. Bioscience, Inc. for the registration of 1,096,634
shares of its common stock issuable upon exercise of certain warrants issued
pursuant to the January 19, 1995 settlement of certain class-action suits and
derivative litigations brought against U.S. Bioscience, Inc and the Registration
Statement (Form S-3 No. 33-00077) and related prospectus of U.S. Bioscience,
Inc. for the registration of 8,142,578 shares of its common stock issuable in
connection with the December 1995 private placement, of our report dated
February 16, 1996, with respect to the consolidated financial statements of U.S.
Bioscience, Inc. included in this Annual Report (Form 10-K) for the year ended
December 31, 1995.



                                                               ERNST & YOUNG LLP

Philadelphia, Pennsylvania
March 20, 1996