Exhibit 16.1
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August 28, 1997

Securities and Exchange Commission
450 5th Street, N.W.
Washington, D.C. 20549

Gentlemen,

We have read the statements made by IGI, Inc., (copy attached), which we
understand will be filed with the Commission, pursuant to Item 4 of the revised
Form 8-K, in response to the comment letter received from the commission dated
August 27, 1997. We agree with the statements concerning our Firm in the revised
Form 8-K.

Very truly yours,

Coopers & Lybrand L.L.P.