SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    Form 8-K


                Current Report Pursuant to Section 13 or 15(d) of
                       The Securities Exchange Act of 1934



      Date of Report (Date of earliest event reported):   September 17, 1997
                                                        --------------------


                            NEOSE TECHNOLOGIES, INC.
             ------------------------------------------------------
             (Exact name of registrant as specified in its charter)



      Delaware                    0-27718                      13-3549286
  ---------------              ------------               -------------------
  (State or other              (Commission                   (IRS Employer
  jurisdiction of              File Number)               Identification No.)
  incorporation)



   102 Witmer Road, Horsham, Pennsylvania                         19044
   --------------------------------------                       ----------
  (Address of principal executive offices)                      (Zip Code)



       Registrant's telephone number, including area code:    (215) 441-5890
                                                          ---------------------



          -------------------------------------------------------------
          (Former name or former address, if changed since last report)



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Item 5.  OTHER EVENTS.

Shareholder Rights Plan.

         On September 17, 1997, the Board of Directors of Neose Technologies,
Inc. (the "Company") declared a dividend distribution of one right (a "Right")
for each outstanding share of Common Stock, $.01 par value ("Common Share"), of
the Company to stockholders of record at the close of business on October 6,
1997. Each Right entitles the registered holder to purchase from the Company a
unit consisting of one one-hundredth of a share (a "Unit") of the Series A
Junior Participating Preferred Stock, $.01 par value ("Preferred Share"), of the
Company, or a combination of securities and assets of equivalent value, at a
purchase price of $150.00 per Unit (the "Purchase Price"), subject to
adjustment. The description and terms of the Rights are set forth in a Rights
Agreement (the "Rights Agreement") between the Company and American Stock
Transfer & Trust Company, as Rights Agent.

         Initially, ownership of the Rights will be evidenced by the Common
Share certificates representing shares then outstanding, and no separate
certificates evidencing the Rights ("Rights Certificates") will be distributed.
The Rights will separate from the Common Shares and a Distribution Date will
occur upon the earlier of (i) 10 days following a public announcement that a
person or group of affiliated or associated persons (an "Acquiring Person") has
acquired, or obtained the right to acquire, beneficial ownership of 15% or more
of the outstanding Common Shares (the "Stock Acquisition Date"), or (ii) the
close of business on such date as may be fixed by the Board of Directors, which
date shall not be more than 65 days following the commencement of a tender offer
or exchange offer that would result in a person or group beneficially owning 15%
or more of the outstanding Common Shares. Until the Distribution Date, (i) the
Rights will be evidenced by the Common Share certificates and will be
transferred with and only with such Common Share certificates, (ii) new Common
Share certificates issued after October 6, 1997 will contain a notation
incorporating the Rights Agreement by reference and (iii) the surrender for
transfer of any certificates for Common Shares outstanding will also constitute
the transfer of the Rights associated with the Common Shares represented by such
certificates.

         The Rights are not exercisable until the Distribution Date and will
expire at the close of business on October 6, 2007, unless earlier redeemed by
the Company as described below or unless a transaction under Section 13(d) of
the Rights Agreement has occurred.

         As soon as practicable after the Distribution Date, Rights Certificates
will be mailed to holders of record of the Common Shares as of the close of
business on the Distribution Date and, thereafter, the separate Rights
Certificates alone will represent the Rights. Except as otherwise determined by
the Board of Directors, and except in connection with the exercise of employee
stock options or stock appreciation rights or under any other benefit plan for
employees or directors or in connection with the exercise of warrants or
conversion of convertible securities, only Common Shares issued after October 6,
1997 and prior to the Distribution Date will be issued with Rights.

         Except in the circumstances described below, after the Distribution
Date each Right will be exercisable for one one-hundredth of a Preferred Share
(a "Preferred Share Fraction"). Each Preferred Share Fraction carries voting and
dividend rights that are intended to produce the equivalent of one Common Share.
The voting and dividend rights of the Preferred Shares are subject to adjustment
in the event of dividends, subdivisions and combinations with respect to the
Common Shares of the Company. In lieu of issuing certificates for Preferred
Share Fractions that are less than an integral multiple of one Preferred Share
(i.e., 100 Preferred Share Fractions), the Company may pay cash representing the
current market value of the Preferred Share Fractions.

         In the event that at any time following the Stock Acquisition Date, (i)
the Company is the surviving corporation in a merger with an Acquiring Person
and its Common Shares remain outstanding, (ii) a Person becomes the beneficial
owner of more than 15% of the then outstanding Common Shares other than pursuant
to a tender offer that provides fair value to all stockholders, (iii) an
Acquiring Person engages in one or more "self-dealing" transactions as set forth
in the Rights Agreement, or (iv) during such time as there is an Acquiring
Person an event occurs that results in such Acquiring Person's ownership
interest being increased by more than 1% (e.g., a reverse stock split), each
holder of a Right will thereafter have the right to receive, upon exercise,
Common Shares (or, in certain circumstances, cash,


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property or other securities of the Company) having a value equal to two times
the exercise price of the Right. In lieu of requiring payment of the Purchase
Price upon exercise of the Rights following any such event, the Company may
permit the holders simply to surrender the Rights, in which event they will be
entitled to receive Common Shares (and other property, as the case may be) with
a value of 50% of what could be purchased by payment of the full Purchase Price.
Notwithstanding any of the foregoing, following the occurrence of any of the
events set forth in clauses (i), (ii), (iii) or (iv) of this paragraph, all
Rights that are, or (under certain circumstances specified in the Rights
Agreement) were, beneficially owned by any Acquiring Person who was involved in
the transaction giving rise to any such event will be null and void. However,
Rights are not exercisable following the occurrence of any of the events set
forth above until such time as the Rights are no longer redeemable by the
Company as set forth below.

         For example, at an exercise price of $150.00 per Right, each Right not
otherwise voided following an event set forth in the preceding paragraph would
entitle its holder to purchase $300.00 worth of Common Shares (or other
consideration, as noted above) for $150.00. Assuming that the Common Shares had
a per share value of $50.00 at such time, the holder of each valid Right would
be entitled to purchase six Common Shares for $150.00. Alternatively, the
Company could permit the holder to surrender each Right in exchange for stock or
cash equivalent to three Common Shares (with a value of $150.00) without the
payment of any consideration other than the surrender of the Right.

         In the event that at any time following the Stock Acquisition Date, (i)
the Company is acquired in a merger or other business combination transaction in
which the Company is not the surviving corporation (other than a merger that is
described in, or that follows a tender offer or exchange offer described in, the
second preceding paragraph), or (ii) 50% or more of the Company's assets or
earning power is sold or transferred, each holder of a Right (except Rights that
previously have been voided as set forth above) shall thereafter have the right
to receive, upon exercise, common shares of the acquiring company having a value
equal to two times the exercise price of the Right. Again, provision is made to
permit surrender of the Rights in exchange for one-half of the value otherwise
purchasable. The events set forth in this paragraph and in the second preceding
paragraph are referred to as the "Triggering Events."

         The Purchase Price payable, and the number of Units of Preferred Shares
or other securities or property issuable upon exercise of the Rights are subject
to adjustment from time to time to prevent dilution (i) in the event of a stock
dividend on, or a subdivision, combination or reclassification of, the Preferred
Shares, (ii) if holders of the Preferred Shares are granted certain rights or
warrants to subscribe for Preferred Shares or convertible securities at less
than the current market price of the Preferred Shares, or (iii) upon the
distribution to holders of the Preferred Shares of evidences of indebtedness or
assets (excluding dividends out of retained earnings of the Company as specified
in Section 1(a) of the Certificate of Designations establishing and designating
the Preferred Shares) or of subscription rights or warrants (other than those
referred to above).

         With certain exceptions, no adjustment in the Purchase Price will be
required until cumulative adjustments amount to at least 1% of the Purchase
Price. No fractional Units will be issued and, in lieu thereof, an adjustment in
cash will be made based on the market price of the Preferred Shares on the last
trading date prior to the date of exercise.

         At any time until ten days following the Stock Acquisition Date, the
Company may redeem the Rights in whole, but not in part, at a price of $.01 per
Right. That ten-day redemption period may be extended by the Board of Directors
so long as the Rights are still redeemable. Under certain circumstances set
forth in the Rights Agreement, the decision to redeem will require the
concurrence of a majority of the Continuing Directors. Immediately upon the
action of the Board of Directors ordering redemption of the Rights, with, where
required, the concurrence of the Continuing Directors, the Rights will terminate
and the only right of the holders of Rights will be to receive the $.01
redemption price.

         The term "Continuing Directors" means any member of the Board of
Directors of the Company who was a member of the Board prior to the date of the
Rights Agreement, and any person who is subsequently elected to the Board if
such person is recommended or approved by a majority of the Continuing
Directors, but shall not include an Acquiring Person, or an affiliate or
associate of an Acquiring Person, or any representative of the foregoing
entities.


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         Until a Right is exercised, the holder thereof, as such, will have no
rights as a stockholder of the Company, including, without limitation, the right
to vote or to receive dividends. Although the distribution of the Rights will
not be taxable to stockholders or to the Company, stockholders may, depending
upon the circumstances, recognize taxable income in the event that the Rights
become exercisable for Preferred Shares (or other consideration) of the Company
or for common shares of the acquiring company as set forth above.

         Other than those provisions relating to the principal economic terms of
the Rights, any of the provisions of the Rights Agreement may be amended by the
Board of Directors of the Company prior to the Distribution Date. After the
Distribution Date, the provisions of the Rights Agreement may be amended by the
Board (in certain circumstances, with the concurrence of the Continuing
Directors) in order to cure any ambiguity, to make changes that do not adversely
affect the interests of holders of Rights (excluding the interests of any
Acquiring Person), or to shorten or lengthen any time period under the Rights
Agreement, provided, however, that no amendment to adjust the time period
governing redemption shall be made at such time as the Rights are not
redeemable.

         The foregoing summary description of the Rights does not purport to be
complete and is qualified in its entirety by reference to the Rights Agreement.


Item 7.  FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS.

         (a)    Financial Statements of Businesses Acquired:  None

         (b)    Pro Forma Financial Information:  None

         (c)    Exhibits:  Reference is made to the Exhibit Index annexed hereto
                and made a part hereof.


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                                   SIGNATURES


         Pursuant to the requirements of the Securities Exchange Act of 1934,
the Registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.

                                      NEOSE TECHNOLOGIES, INC.



                                      By: /s/ Stephen A. Roth
                                          -------------------------------------
                                          Stephen A. Roth
                                          Chairman and Chief Executive Officer


Dated:  October 1, 1997






                                  EXHIBIT INDEX


Exhibit

   3.1   Second Amended and Restated Certificate of Incorporation of Neose 
         Technologies, Inc. (Exhibit 3.2)(1)

   3.2*  Certificate of Designations establishing and designating the Series A
         Junior Participating Preferred Stock.

   3.3*  Amended and Restated By-Laws of Neose Technologies, Inc.

   4.1*  Rights Agreement, dated as of September 26, 1997, between Neose 
         Technologies, Inc. and American Stock Transfer & Trust Company, as 
         Rights Agent.

  99.1*  Press release, dated September 19, 1997.

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*        Filed herewith.

(1)      Filed as an Exhibit to Neose Technologies, Inc.'s Registration
         Statement on Form S-1 (Reg. No. 33-80693) filed with the Securities and
         Exchange Commission on December 21, 1995, as amended.