SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

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                                    FORM 8-A

                FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES
                     PURSUANT TO SECTION 12(b) OR (g) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

                               CELGENE CORPORATION
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             (Exact name of registrant as specified in its charter)

               Delaware                                    22-2711928
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(State of incorporation or organization)       (IRS Employer Identification No.)

                  7 Powder Horn Drive, Warren, New Jersey 07059
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                    (Address of principal executive offices)

        Securities to be registered pursuant to Section 12(b) of the Act:

                                      NONE
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        Securities to be registered pursuant to Section 12(g) of the Act:

                          Common Stock Purchase Rights
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                                (Title of Class)

                                                                 
                                                                      







Item 1. Description of Registrant's Securities to be Registered.

        On September 16, 1996, the Board of Directors of Celgene Corporation
(the "Corporation") declared a dividend distribution of one right (a "Right") to
purchase one one-tenth of a share of the Common Stock, $0.01 par value, of the
Corporation (the "Common Shares") for each outstanding share of Common Stock,
payable to the stockholders of record on September 26, 1996 (the "Record Date").
The Board of Directors also authorized and directed the issuance of one Right
with respect to each Common Share issued thereafter until the Distribution Date
(as defined below) and, in certain circumstances, with respect to Common Shares
issued after the Distribution Date. Except as set forth below, each Right, when
it becomes exercisable, entitles the registered holder to purchase from the
Corporation one one-tenth of a Common Share at a price of $100.00 per whole
Common Share (the "Purchase Price"), subject to adjustment. The description and
terms of the Rights are set forth in a Rights Agreement (the "Rights Agreement")
between the Corporation and American Stock Transfer & Trust Company, as Rights
Agent (the "Rights Agent"), dated as of September 16, 1996.

        Initially, the Rights will be attached to all certificates representing
Common Shares then outstanding, and no separate Right Certificates will be
distributed. The Rights will separate from the Common Shares upon the earliest
to occur of (i) a person or group of affiliated or associated persons having
acquired beneficial ownership of 15% or more of the outstanding Common Shares
(except pursuant to a Permitted Offer, as hereinafter defined); or (ii) 10 days
(or such later date as the Board of Directors may determine) following the
commencement of, or announcement of an intention to make, a tender offer or
exchange offer the consummation of which would result in a person or group
becoming an Acquiring Person (as hereinafter defined) (the earliest of such
dates being called the "Distribution Date"). A person or group whose acquisition
of Common Shares causes a Distribution Date pursuant to clause (i) above is an
"Acquiring Person." The date that a person or group becomes an Acquiring Person
is the "Shares Acquisition Date." A person who acquires Common Shares pursuant
to a tender or exchange offer which is for all outstanding Common Shares at a
price and on terms which a majority of the Board of Directors determines (prior
to acquisition) to be adequate and in the best interests of the Corporation and
its stockholders (other than such person, its affiliates and associates) (a
"Permitted Offer") will not be deemed to be an Acquiring Person and such
person's ownership will not constitute a Distribution Date.

        The Rights Agreement provides that, until the Distribution Date, the
Rights will be transferred with and only with the Common Shares. Until the
Distribution Date (or earlier redemption or expiration of the Rights), new
Common Share certificates issued after the Record Date upon the transfer or new
issuance of Common Shares will contain a notation incorporating the Rights
Agreement by reference. Until the Distribution Date (or earlier redemption or
expiration of the Rights), the surrender for transfer of any certificates for
Common Shares outstanding as of the Record Date, even without such notation or a
copy of this Summary of Rights being attached thereto, will also constitute the
transfer of the Rights associated with the Common Shares represented by such
certificate. As soon as practicable

                                                                 
                                                                      







following the Distribution Date, separate certificates evidencing the Rights
("Right Certificates") will be mailed to holders of record of the Common Shares
as of the close of business on the Distribution Date (and to each initial record
holder of certain Common Shares issued after the Distribution Date), and such
separate Right Certificates alone will evidence the Rights.

        The Rights are not exercisable until the Distribution Date, and will
expire at the close of business on September 15, 2006, unless earlier redeemed
by the Corporation as described below.

        In the event that any person becomes an Acquiring Person, each holder of
Rights (other than Rights that have become void as described below) will
thereafter have the right (the "Flip-In Right") to receive, upon exercise of
such Rights, the number of Common Shares (or, in certain circumstances, other
securities of the Corporation) having a value (immediately prior to such
triggering event) equal to two times the aggregate exercise price of such
Rights. The Board, at its option, may exchange each Right (other than those that
have become void as described below) for one Common Share in lieu of the Flip-In
Right, provided no person is the beneficial owner of 50% or more of the Common
Shares at the time of such exchange. Notwithstanding the foregoing, following
the occurrence of the event described above, all Rights that are or (under
certain circumstances specified in the Rights Agreement) were beneficially owned
by any Acquiring Person or any affiliate or associate thereof will be null and
void.

        In the event that, at any time following the Shares Acquisition Date,
(i) the Corporation is acquired in a merger or other business combination
transaction in which the holders of all of the outstanding Common Shares
immediately prior to the consummation of the transaction are not the holders of
all of the surviving corporation's voting power, or (ii) more than 50% of the
Corporation's assets or earning power is sold or transferred, then each holder
of Rights (except Rights which previously have been voided as set forth above)
shall thereafter have the right (the "Flip-Over Right") to receive, upon
exercise of such Rights, common shares of the acquiring company having a value
equal to two times the aggregate exercise price of the Rights; provided,
however, that the Flip Over Right shall not apply to any transaction described
in clause (i) if (x) such transaction is with a person or persons (or a wholly
owned subsidiary of any such person or persons) that acquired Common Shares
pursuant to a Permitted Offer and (y) the price and form of consideration
offered in such transaction is the same as that paid to all holders of Common
Shares whose shares were purchased to the Permitted Offer. The holder of a Right
will continue to have the Flip-Over Right whether or not such holder exercises
or surrenders the Flip-In Right.

        The Purchase Price payable, and the number of Common Shares or other
securities issuable, upon exercise of the Rights are subject to adjustment from
time to time to prevent dilution (i) in the event of a stock dividend on, or a
subdivision, combination or reclassification of, the Common Shares, (ii) upon
the grant to holders of the Common Shares of certain rights or warrants to
subscribe for or purchase Common Shares at a price, or securities convertible
into Common Shares with a conversion price, less than the then current 
                                                                      







market price of the Common Shares, or (iii) upon the distribution to holders of
the Common Shares of evidences of indebtedness or assets (excluding regular
quarterly cash dividends) or of subscription rights or warrants (other than
those referred to above).

        With certain exceptions, no adjustment in the Purchase Price will be
required until cumulative adjustments require an adjustment of at least 1% in
such Purchase Price. No fractional Common Shares will be issued and, in lieu
thereof, an adjustment in cash will be made based on the market price of the
Common Shares on the last trading day prior to the date of exercise.

        At any time prior to the earlier to occur of (i) a person becoming an
Acquiring Person or (ii) the expiration of the Rights, the Corporation may
redeem the Rights in whole, but not in part, at a price of $.01 per Right (the
"Redemption Price"), which redemption shall be effective at such time, on such
basis and with such conditions as the Board of Directors may establish in its
sole discretion. The Corporation may, at its option, pay the Redemption Price in
Common Shares.

        All of the provisions of the Rights Agreement may be amended by the
Board of Directors prior to the Distribution Date. After the Distribution Date,
the provisions of the Rights Agreement may be amended by the Board in order to
cure any ambiguity, defect or inconsistency, to make changes which do not
adversely affect the interests of holders of Rights (excluding the interests of
any Acquiring Person), or, subject to certain limitations, to shorten or
lengthen any time period under the Rights Agreement.

        Until a Right is exercised, the holder thereof, as such, will have no
rights as a stockholder of the Corporation, including, without limitation, the
right to vote or to receive dividends. While the distribution of the Rights will
not be taxable to stockholders of the Corporation, stockholders may, depending
upon the circumstances, recognize taxable income should the Rights become
exercisable or upon the occurrence of certain events thereafter.

        The Rights have certain anti-takeover effects. The Rights will cause
substantial dilution to a person or group that attempts to acquire the Company
on terms not approved by the Board of Directors, except pursuant to an offer
conditioned on a substantial number of Rights being acquired. The Rights should
not interfere with any merger or other business combination approved by the
Board of Directors, as the Rights may be redeemed by the Corporation at $.01 per
Right prior to the time that a person or group has acquired beneficial ownership
of 15% or more of the Common Shares.

        The Rights Agreement, dated as of September 16, 1996, between the
Corporation and American Stock Transfer & Trust Company, as Rights Agent,
specifying the terms of the Rights is attached hereto as an exhibit and is
incorporated herein by reference. The foregoing description of the Rights is
qualified in its entirety by reference to such exhibit.

Item 2. Exhibits.

                                                                 
                                                                      








        1.     Rights Agreement dated as of September 16, 1996 between Celgene
               Corporation and American Stock Transfer & Trust Company, with the
               form of Right Certificate attached as Exhibit A thereto and the
               Summary of Rights to Purchase Shares attached as Exhibit B
               thereto.

                                                                 
                                                                      










                                    SIGNATURE

        Pursuant to the requirement of Section 12 of the Securities Exchange Act
of 1934, the registrant has duly caused this registration statement to be signed
on its behalf by the undersigned, thereunto duly authorized.

Dated:         September 16, 1996

                                            CELGENE CORPORATION

                                     By:      /S/ JOHN W. JACKSON
                                        --------------------------------
                                     Name:   John W. Jackson
                                     Title: Chairman and Chief Executive Officer

                                                                 
                                                                      










                                  EXHIBIT LIST

        1.     Rights Agreement dated as of September 16, 1996 between Celgene
               Corporation and American Stock Transfer & Trust Company, the form
               of Right Certificate as Exhibit A and the Summary of Rights to
               Purchase Shares as Exhibit B.